The inflammatory markers CRP, IL-6, and IL-10 are associated with cognitive function-data from the Berlin Aging Study II

Neurobiology of Aging

Volumn 38, Issue , 2016, Pages 112-117

  Tegeler, Christina ^a   O'Sullivan, Julie Lorraine ^a   Bucholtz, Nina ^a   Goldeck, David ^b   Pawelec, Graham ^b   Steinhagen Thiessen, Elisabeth ^a   Demuth, Ilja ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

C reactive protein; Cognitive function; Cytokine; Executive function; Inflammation; Memory

Indexed keywords

C REACTIVE PROTEIN; INTERLEUKIN 10; INTERLEUKIN 6; AUTACOID;

ADULT; AGED; ARTICLE; COGNITION; CONTROLLED STUDY; DRUG TARGETING; EPISODIC MEMORY; EXECUTIVE FUNCTION; FEMALE; HUMAN; INFLAMMATION; INNATE IMMUNITY; MALE; NEUROPSYCHOLOGICAL TEST; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; VERBAL MEMORY; BLOOD; MIDDLE AGED; PHYSIOLOGY; STATISTICAL MODEL; VERY ELDERLY;

AGED; AGED, 80 AND OVER; C-REACTIVE PROTEIN; COGNITION; EXECUTIVE FUNCTION; FEMALE; HUMANS; IMMUNITY, INNATE; INFLAMMATION MEDIATORS; INTERLEUKIN-10; INTERLEUKIN-6; LINEAR MODELS; MALE; MIDDLE AGED;

EID: 84962215876     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2015.10.039     Document Type: Article

References (39)

1. Ahmadi-Abhari S., Luben R.N., Wareham N.J., Khaw K.T. Distribution and determinants of C-reactive protein in the older adult population: European Prospective Investigation into Cancer-Norfolk study. Eur. J. Clin. Invest. 2013, 43:899-911.
2. Bertram L., BockenhoffA., Demuth I., Duzel S., Eckardt R., Li S.C., Lindenberger U., Pawelec G., Siedler T., Wagner G.G., Steinhagen-Thiessen E. Cohort profile: the Berlin Aging Study II (BASE-II). Int. J. Epidemiol. 2014, 43:703-712.
3. Bettcher B.M., Wilheim R., Rigby T., Green R., Miller J.W., Racine C.A., Yaffe K., Miller B.L., Kramer J.H. C-reactive protein is related to memory and medial temporal brain volume in older adults. Brain Behav. Immun. 2012, 26:103-108.
4. Carlson M.C., Xue Q.L., Zhou J., Fried L.P. Executive decline and dysfunction precedes declines in memory: the Women's Health and Aging Study II. J. Gerontol. A Biol. Sci. Med. Sci. 2009, 64:110-117.
5. Cevenini E., Monti D., Franceschi C. Inflamm-ageing. Curr. Opin. Clin. Nutr. Metab. Care 2013, 16:14-20.
6. Chan R.C., Shum D., Toulopoulou T., Chen E.Y. Assessment of executive functions: review of instruments and identification of critical issues. Arch. Clin. Neuropsychol. 2008, 23:201-216.
7. Chung C.C., Pimentel D., Jor'dan A.J., Hao Y., Milberg W., Novak V. Inflammation-associated declines in cerebral vasoreactivity and cognition in type 2 diabetes. Neurology 2015, 85:450-458.
8. Deary I.J., Corley J., Gow A.J., Harris S.E., Houlihan L.M., Marioni R.E., Penke L., Rafnsson S.B., Starr J.M. Age-associated cognitive decline. Br. Med. Bull 2009, 92:135-152.
9. Dik M.G., Jonker C., Comijs H.C., Deeg D.J., Kok A., Yaffe K., Penninx B.W. Contribution of metabolic syndrome components to cognition in older individuals. Diabetes Care 2007, 30:2655-2660.
10. Festa A., D'Agostino R., Howard G., Mykkanen L., Tracy R.P., Haffner S.M. Chronic subclinical inflammation as part of the insulin resistance syndrome: the Insulin Resistance Atherosclerosis Study (IRAS). Circulation 2000, 102:42-47.
11. Field A.P. Discovering Statistics Using SPSS 2005, Sage Publications, London. second ed.
12. Hoth K.F., Haley A.P., Gunstad J., Paul R.H., Poppas A., Jefferson A.L., Tate D.F., Ono M., Jerskey B.A., Cohen R.A. Elevated C-reactive protein is related to cognitive decline in older adults with cardiovascular disease. J. Am. Geriatr. Soc. 2008, 56:1898-1903.
13. Knopman D., Boland L.L., Mosley T., Howard G., Liao D., Szklo M., McGovern P., Folsom A.R. Cardiovascular risk factors and cognitive decline in middle-aged adults. Neurology 2001, 56:42-48. Atherosclerosis Risk in Communities (ARIC) Study Investigators.
14. Komulainen P., Lakka T.A., Kivipelto M., Hassinen M., Penttila I.M., Helkala E.L., Gylling H., Nissinen A., Rauramaa R. Serum high sensitivity C-reactive protein and cognitive function in elderly women. Age Ageing 2007, 36:443-448.
15. Kuo H.K., Yen C.J., Chang C.H., Kuo C.K., Chen J.H., Sorond F. Relation of C-reactive protein to stroke, cognitive disorders, and depression in the general population: systematic review and meta-analysis. Lancet Neurol. 2005, 4:371-380.
16. Lezak M.D., Howieson D.B., Loring D.W. Neuropsychological Assessment 2004, Oxford university press, New York. fourth ed.
17. Lim A., Krajina K., Marsland A.L. Peripheral inflammation and cognitive aging. Mod. Trends Pharmacopsychiatri. 2013, 28:175-187.
18. Marsland A.L., Gianaros P.J., Abramowitch S.M., Manuck S.B., Hariri A.R. Interleukin-6 covaries inversely with hippocampal grey matter volume in middle-aged adults. Biol. Psychiatry 2008, 64:484-490.
19. Marsland A.L., Gianaros P.J., Kuan D.C., Sheu L.K., Krajina K., Manuck S.B. Brain morphology links systemic inflammation to cognitive function in midlife adults. Brain Behav. Immun. 2015, 48:195-204.
20. Marsland A.L., Petersen K.L., Sathanoori R., Muldoon M.F., Neumann S.A., Ryan C., Flory J.D., Manuck S.B. Interleukin-6 covaries inversely with cognitive performance among middle-aged community volunteers. Psychosom Med. 2006, 68:895-903.
21. Miller A.A., Spencer S.J. Obesity and neuroinflammation: a pathway to cognitive impairment. Brain Behav. Immun. 2014, 42:10-21.
22. Mooijaart S.P., Sattar N., Trompet S., Lucke J., Stott D.J., Ford I., Ford I., Jukema J.W., Westendorp R.G., de Craen A.J. Circulating interleukin-6 concentration and cognitive decline in old age: the PROSPER study. J. Intern. Med. 2013, 274:77-85. PROSPER Study Group.
23. Morrisette-Thomas V., Cohen A.A., Fulop T., Riesco E., Legault V., Li Q., Milot E.1, Dusseault-Bélanger F., Ferrucci L. Inflamm-aging does not simply reflect increases in pro-inflammatory markers. Mech. Ageing Dev. 2014, 139:49-57.
24. Myers G.L., Rifai N., Tracy R.P., Roberts W.L., Alexander R.W., Biasucci L.M., Catravas J.D., Cole T.G., Cooper G.R., Khan B.V., Kimberly M.M., Stein E.A., Taubert K.A., Warnick G.R., Waymack P.P. CDC/AHA Workshop on Markers of Inflammation and Cardiovascular Disease: Application to Clinical and Public Health Practice: report from the laboratory science discussion group. Circulation 2004, 110:e545-549. CDC, AHA.
25. Pawelec G., Goldeck D., Derhovanessian E. Inflammation, ageing and chronic disease. Curr. Opin. Immunol. 2014, 29:23-28.
26. RadloffL.S. The CES-D scale a self-report depression scale for research in the general population. Appl. Psychol. Meas. 1977, 1:385-401.
27. Salthouse T.A. Relations between cognitive abilities and measures of executive functioning. Neuropsychology 2005, 19:532-545.
28. Satizabal C.L., Zhu Y.C., Mazoyer B., Dufouil C., Tzourio C. Circulating IL-6 and CRP are associated with MRI findings in the elderly: the 3C-Dijon Study. Neurology 2012, 78:720-727.
29. Schram M.T., Euser S.M., de Craen A.J., Witteman J.C., Frolich M., Hofman A., Jolles J., Breteler M.M., Westendorp R.G. Systemic markers of inflammation and cognitive decline in old age. J. Am. Geriatr. Soc. 2007, 55:708-716.
30. Simen A.A., Bordner K.A., Martin M.P., Moy L.A., Barry L.C. Cognitive dysfunction with aging and the role of inflammation. Ther. Adv. Chronic Dis. 2011, 2:175-195.
31. Spira D., Buchmann N., Nikolov J., Demuth I., Steinhagen-Thiessen E., Eckardt R., Norman K. Association of low lean mass with frailty and physical performance: a comparison between two operational definitions of sarcopenia-data from the Berlin Aging Study II (BASE-II). J. Gerontol. A Biol. Sci. Med. Sci. 2015, 70:779-784.
32. Stolp H.B., Dziegielewska K.M. Review: role of developmental inflammation and blood-brain barrier dysfunction in neurodevelopmental and neurodegenerative diseases. Neuropathol. Appl. Neurobiol. 2009, 35:132-146.
33. Strauss E., Sherman E.M.S., Spreen O. A Compendium of Neuropsychological Tests: Administration, Norms, and Commentary 2006, Oxford University Press, New York. third ed.
34. Tewes U. HAWIE-R: Hamburger Wechsler Intelligenztest für Erwachsene 1991, Revision, Bern.
35. Weaver J.D., Huang M.H., Albert M., Harris T., Rowe J.W., Seeman T.E. Interleukin-6 and risk of cognitive decline: MacArthur studies of successful aging. Neurology 2002, 59:371-378.
36. Wersching H., Duning T., Lohmann H., Mohammadi S., Stehling C., Fobker M., Conty M., Minnerup J., Ringelstein E.B., Berger K., Deppe M., Knecht S. Serum C-reactive protein is linked to cerebral microstructural integrity and cognitive function. Neurology 2010, 74:1022-1029.
37. Wilson C.J., Finch C.E., Cohen H.J. Cytokines and cognition-the case for a head-to-toe inflammatory paradigm. J. Am. Geriatr. Soc. 2002, 50:2041-2056.
38. Windham B.G., Simpson B.N., Lirette S., Bridges J., Bielak L., Peyser P.A., Kullo I., Turner S., Griswold M.E., Mosley T.H. Associations between inflammation and cognitive function in African Americans and European Americans. J. Am. Geriatr. Soc. 2014, 62:2303-2310.
39. Yaffe K., Kanaya A., Lindquist K., Simonsick E.M., Harris T., Shorr R.I., Tylavsky F.A., Newman A.B. The metabolic syndrome, inflammation, and risk of cognitive decline. JAMA 2004, 292:2237-2242.