Age-associated cognitive decline

British Medical Bulletin

Volumn 92, Issue 1, 2009, Pages 135-152

  Deary, Ian J ^a   Corley, Janie ^a   Gow, Alan J ^a   Harris, Sarah E ^a   Houlihan, Lorna M ^a   Marioni, Riccardo E ^a   Penke, Lars ^a   Rafnsson, Snorri B ^a   Starr, John M ^a,b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b Royal Victoria Hospital Edinburgh   (United Kingdom)

Author keywords

Ageing; Cardiovascular; Cognition; Genetics; Inflammation; Intelligence; Memory

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ARACHIDIC ACID; ASCORBIC ACID; BETA CAROTENE; CYANOCOBALAMIN; DOCOSAHEXAENOIC ACID; FISH OIL; FLAVONOID; FOLIC ACID; OMEGA 3 FATTY ACID; PYRIDOXINE; VITAMIN B GROUP;

ACUTE HEART INFARCTION; ADULTHOOD; AGING; ALERTNESS; ALZHEIMER DISEASE; ARTERY DISEASE; BRAIN; BRAIN ATHEROSCLEROSIS; BRAIN INFARCTION; CARDIOVASCULAR DISEASE; COGNITION; COGNITIVE DEFECT; DEMENTIA; DIET; DIET THERAPY; DIFFUSION TENSOR IMAGING; DISEASE SEVERITY; EFFECT SIZE; ENCEPHALITIS; GENETIC ANALYSIS; GENETICS; HERITABILITY; HUMAN; IN VIVO STUDY; INTELLIGENCE; ISCHEMIC HEART DISEASE; LIFESTYLE; LIFESTYLE MODIFICATION; MEMORY; MENTAL CAPACITY; MENTAL DETERIORATION; MENTAL FUNCTION; MINI MENTAL STATE EXAMINATION; NEUROBIOLOGY; NEUROIMAGING; NEUROPROTECTION; NUCLEAR MAGNETIC RESONANCE IMAGING; NUTRITION; PHENOTYPE; PREVALENCE; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SENESCENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING;

AGING; CARDIOVASCULAR DISEASES; COGNITION; COGNITION DISORDERS; DIET; HEALTH STATUS; HUMANS; LIFE STYLE; RISK FACTORS;

EID: 72049126415     PISSN: 00071420     EISSN: 14718391     Source Type: Journal    
DOI: 10.1093/bmb/ldp033     Document Type: Review

References (49)

1. Brayne C (2007) The elephant in the room: healthy brains in later life, epidemiology and public health. Nat Rev Neurosci, 8, 233-239.
2. Gow J, Gilhooly M (2003) Risk Factors for Dementia and Cognitive Decline. Glasgow: NHS Health Scotland.
3. House of Lords (2005) Ageing: scientific aspects. London: The Stationery Office.
4. Stern PC, Carstensen LL (2000) The Aging Mind. Washington, DC: National Academy Press.
5. Hendrie HC, Albert MS, Butters MA et al. (2006) The NIH Cognitive and Emotional Health Project: report of the Critical Evaluation Study Committee. Alzheimers Dement, 2, 12-32.
6. Foresight Mental Capital and Wellbeing Project (2008) Final Project Report. London: The Government Office for Science.
7. Deary IJ, Whalley LJ, Starr JM (2009) A Lifetime of Intelligence: Follow-up Studies of the Scottish mental Surveys of 1932 and 1947. Washington, DC: American Psychological Association.
8. Hedden T, Gabrieli JDE (2004) Insights into the ageing mind: a view from cognitive neuro-science. Nat Rev Neurosci, 5, 87-96.
9. Park DC, Reuter-Lorenz P (2009) The adaptive brain: aging and neurocognitive scaffolding. Annu Rev Psychol, 60, 173-196.
10. Wilson RS, Beckett LA, Barnes LL et al. (2002) Individual differences in rates of change in cognitive abilities of older persons. Psychol Aging, 17, 179-193.
11. Der G, Deary IJ (2006) Reaction time age changes and sex differences in adulthood. Results from a large, population based study: the UK Health and Lifestyle Survey. Psychol Aging, 21, 62-73.
12. Salthouse TA (2009) When does age-related cognitive decline begin? Neurobiol Aging, 30, 507-514.
13. MRC CFAS. (2001) Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales. Lancet, 357, 169-175.
14. Starr JM, Deary IJ, Macintyre S (2003) Associations with successful ageing in the Healthy Old People in Edinburgh cohort: being well, fit and healthy. Aging Clin Exp Res, 15, 336-342.
15. Deary IJ, Whalley LJ, Batty GD, Starr JM (2006) Physical fitness and lifetime cognitive change. Neurology, 67, 1195-1200.
16. Starr JM, Taylor MD, Hart CL et al. (2004) Childhood mental ability and blood pressure at midlife: linking the Scottish Mental Survey 1932 and the Midspan studies. J Hypertens, 22, 893-898.
17. Deary IJ, Wright AF, Harris SE, Whalley LJ, Starr JM (2004) Searching for genetic influences on normal cognitive ageing. Trends Cogn Sci, 8, 178-184.
18. Deary IJ, Johnson W, Houlihan LM (2009) Genetic foundations of human intelligence. Human Genetics, 126, 215-232.
19. Small BJ, Rosnick CB, Fratiglioni L, Backman L (2004) Apolipoprotein E and cognitive performance: a meta-analysis. Psychol Aging, 19, 592-600.
20. Wisdom NM, Callahan JL, Hawkins KA (in press) The effects of apolipoprotien E on non-impaired cognitive functioning: a meta-analysis. Neurobiol Aging.
21. Houlihan LM, Harris SE, Luciano M et al. (2009) Replication study of candidate genes for cognitive abilities: the Lothian Birth Cohort 1936. Genes Brain Behav, 8, 238-247.
22. Mullen SA, Crompton DE, Carney PW, Helbig I, Berkovic SF (2009) A neurologist's guide to genome-wide association studies. Neurology, 72, 558-565.
23. Waldstein SR, Snow J, Muldoon MF, Katzel LI (2001) Neuropsychological consequences of cardiovascular disease. In Tarter RE, Butters M, Beers SR (eds) Medical Neuropsychology, 2nd ed. New York: Kluwer Academic/Plenum Publishers.
24. Brown GG, Eyler Zorilla LT (2001) Neuropsychological aspects of stroke. In Waldstein SR, Elias MF (eds) Neuropsychology of Cardiovascular Disease. New Jersey: Lawrence Erlbaum Associates.
25. Hochstenbach J, Mulder T, van Limbeek J, Donders R, Schoonderwaldt H (1998) Cognitive decline following stroke: a comprehensive study of cognitive decline following stroke. J Clin Exp Neuropsychol, 20, 503-517.
26. Rafnsson SB, Deary IJ, Fowkes FGR (2009) Peripheral arterial disease and cognitive function. Vasc Med, 14, 51-61.
27. Rafnsson SB, Deary IJ, Smith FB, Whiteman MC, Fowkes FGR (2007) Cardiovascular diseases and decline in cognitive function in an elderly community population: the Edinburgh Artery Study. Psychosom Med, 69, 425-434.
28. Schram MT, Euser SM, de Craen AJM et al. (2007) Systemic Markers of Inflammation and Cognitive Decline in Old Age. J Am Geriatr Soc, 55, 708-716.
29. Weuve J, Ridker PM, Cook NR, Buring JE, Grodstein F (2006) High-sensitivity C-reactive protein and cognitive function in older women. Epidemiology, 17, 183-189.
30. Lowe GDO (2001) Is sticky blood a treatable determinant of cognitive decline and of dementia? Age Ageing, 30, 101-103.
31. Luciano M, Marioni RE, Gow AJ, Starr JM, Deary IJ (in press) Reverse causation in the association between C-reactive protein and fibrinogen levels and cognitive abilities in an ageing sample. Psychosom Med, 71, 404-409.
32. McGurn B, Starr JM, Topfer JA et al. (2004) Pronunciation of irregular words is preserved in dementia, validating premorbid IQ estimation. Neurology, 62, 1184-1186.
33. Raz N, Rodrigue KM (2006) Differential aging of the brain: patterns, cognitive correlates and modifiers. Neurosci Biobehav Rev, 30, 730-748.
34. Sullivan EV, Pfefferbaum A (2006) Diffusion tensor imaging and aging. Neurosci Biobehav Rev, 30, 749-761.
35. Whalley LJ, Deary IJ, Appleton CL, Starr JM (2004) Cognitive reserve and the neurobiology of cognitive aging. Ageing Res Rev, 3, 369-382.
36. Frisoni GB, Galluzzi S, Pantoni L, Filippi M (2007) The effect of white matter lesions on cognition in the elderly: small but detectable. Nat Clin Pract Neurol, 3, 620-627.
37. Ordovas JM (2008) Nutrition and cognitive health. In Foresight Mental Capital and Wellbeing Project. Final Project Report. London: The Government Office for Science.
38. Van Dyk K, Sano M (2007) The impact of nutrition on cognition in the elderly. Neurochem Res, 32, 893-904.
39. Gómez-Pinilla F (2008) Brain foods: the effects of nutrients on brain function. Nat Rev Neurosci, 9, 568-578.
40. Parrott MD, Greenwood CE (2007) Dietary influences on cognitive function with aging: from high-fat diets to healthful eating. Ann NY Acad Sci, 1114, 389-397.
41. Whalley LJ, Deary IJ, Starr JM et al. (2008) Omega 3 fatty acid erythrocyte membrane content, APOE E4 and cognitive variation: an observational follow-up study in late adulthood. Am J Clin Nutr, 87, 449-454.
42. Ganguli M, Vander Bilt J, Saxton JA, Shen C, Dodge HH (2005) Alcohol consumption and cognitive function in late life: a longitudinal community study. Neurology, 65, 1210-1217.
43. Nooyens ACJ, van Gelder BM, Verschuren M (2008) Smoking and cognitive decline among middle-aged men and women: the Doetinchem Cohort Study. Am J Public Health, 98, 2244-2250.
44. Fratiglioni L, Paillard-Borg S, Winblad B (2004) An active and socially integrated lifestyle in late life might protect against dementia. Lancet Neurol, 3, 343-353.
45. Kramer AF, Bherer L, Colcombe SJ, Dong W, Greenough WT (2004) Environmental influences on cognitive and brain plasticity during aging. J Gerontol, 59A, 940-957.
46. Richards M, Deary IJ (2005) A life course approach to cognitive reserve: a model for cognitive aging and development? Ann Neurol, 58, 617-622.
47. Papp KV, Walsh SJ, Snyder PJ (2009) Immediate and delayed effects of cognitive interventions in healthy elderly: a review of current literature and future directions. Alzheimers Dement, 5, 50-60.
48. Haworth CM, Wright MJ, Luciano M et al. (in press) The heritability of general cognitive ability increases linearly from childhood to young adulthood. Mol Psychiatry.
49. Poduslo SE, Huang R, Spiro A (in press) A genome screen of successful aging without cognitive decline identifies LRP1B by haplotype analysis. Am J Med Genet B Neuropsychiatr Genet.