-
1
-
-
0024841814
-
Major histocompatibility complex structure and function
-
Altmann DM, Trowsdale J. Major histocompatibility complex structure and function. Curr Opin Immunol 1989; 2:93-98
-
(1989)
Curr Opin Immunol
, vol.2
, pp. 93-98
-
-
Altmann, D.M.1
Trowsdale, J.2
-
2
-
-
20544460101
-
HLA associated genetic predisposition to autoimmune diseases: Genes involved and possible mechanisms
-
Thorsby E, Lie BA HLA associated genetic predisposition to autoimmune diseases: Genes involved and possible mechanisms. Transpl Immunol 2005; 14: 175-182
-
(2005)
Transpl Immunol
, vol.14
, pp. 175-182
-
-
Thorsby, E.1
Lie, B.A.2
-
4
-
-
0023252262
-
HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus
-
Todd JA, Bell JI, McDevitt HO HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature 1987; 329: 599-604
-
(1987)
Nature
, vol.329
, pp. 599-604
-
-
Todd, J.A.1
Bell, J.I.2
McDevitt, H.O.3
-
5
-
-
0025331496
-
Analysis of HLA-DQ genotypes and susceptibility in insulin-dependent diabetes mellitus
-
Baisch JM, Weeks T, Giles R., Hoover M, Stastny P, Capra JD Analysis of HLA-DQ genotypes and susceptibility in insulin-dependent diabetes mellitus. N Engl J Med 1990; 322:1836-1841
-
(1990)
N Engl J Med
, vol.322
, pp. 1836-1841
-
-
Baisch, J.M.1
Weeks, T.2
Giles, R.3
Hoover, M.4
Stastny, P.5
Capra, J.D.6
-
6
-
-
0001657878
-
Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: A family study
-
Morel PA, Dorman JS, Todd J.A., McDevitt HO, Trucco M. Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study. Proc Natl Acad Sci U S A 1988; 85:8111-8115
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 8111-8115
-
-
Morel, P.A.1
Dorman, J.S.2
Todd, J.A.3
McDevitt, H.O.4
Trucco, M.5
-
7
-
-
0033311161
-
∗0602 allele in unaffected, islet cell antibody-positive first degree relatives and in rare patients with type 1 diabetes
-
∗0602 allele in unaffected, islet cell antibody-positive first degree relatives and in rare patients with type 1 diabetes. J Clin Endocrinol Metab 1999; 84:1722-1778
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 1722-1778
-
-
Pugliese, A.1
Kawasaki, E.2
Zeller, M.3
-
9
-
-
0001330676
-
HLA class II associations in insulin-dependent diabetes mellitus among blacks, caucasians, and Japanese
-
Japan, 6-13 November Tsuji K, Aizawa M, Sasazuki T, Eds. Eds. Oxford University Press
-
Rønningen KS, Spurkland A, Tait BD, et al. HLA class II associations in insulin-dependent diabetes mellitus among Blacks, Caucasians, and Japanese. In HLA 1991: Proceedings of the Eleventh International Histocompatibility Workshop and Conference Held in Yokohoma, Japan, 6-13 November, 1991. Tsuji K, Aizawa M, Sasazuki T, Eds. Eds. Oxford University Press, 1993, p. 713-722
-
(1991)
HLA 1991: Proceedings of the Eleventh International Histocompatibility Workshop and Conference Held in Yokohoma
, pp. 713-722
-
-
Rønningen, K.S.1
Spurkland, A.2
Tait, B.D.3
-
10
-
-
0031463302
-
Genetic protection from insulin-dependent diabetes mellitus
-
Pugliese A. Genetic protection from insulin-dependent diabetes mellitus. Diabetes Nutr Metab 1997; 10:169-179
-
(1997)
Diabetes Nutr Metab
, vol.10
, pp. 169-179
-
-
Pugliese, A.1
-
11
-
-
0026647948
-
An explanation for the neutral effect of DR2 on IDDM susceptibility in Central Italy
-
Sorrentino R, De Grazia U, Buzzetti R, et al An explanation for the neutral effect of DR2 on IDDM susceptibility in central Italy. Diabetes 1992; 41:904-908
-
(1992)
Diabetes
, vol.41
, pp. 904-908
-
-
Sorrentino, R.1
De Grazia, U.2
Buzzetti, R.3
-
12
-
-
0026004701
-
A new HLA-DR2 extended haplotype is involved in insulin-dependent diabetes mellitus susceptibility
-
Carcassi C, Trucco G, Trucco M., Contu L. A new HLA-DR2 extended haplotype is involved in insulin-dependent diabetes mellitus susceptibility. Hum Immunol 1991; 31:159-164
-
(1991)
Hum Immunol
, vol.31
, pp. 159-164
-
-
Carcassi, C.1
Trucco, G.2
Trucco, M.3
Contu, L.4
-
13
-
-
0026554696
-
Extensive study of DRB, DQA, and DQB gene polymorphism in 23 DR2-positive, insulin-dependent diabetes mellitus patients
-
Zeliszewski D, Tiercy JM, Boitard C, et al Extensive study of DRB, DQA, and DQB gene polymorphism in 23 DR2-positive, insulin-dependent diabetes mellitus patients. Hum Immunol 1992; 33:140-147
-
(1992)
Hum Immunol
, vol.33
, pp. 140-147
-
-
Zeliszewski, D.1
Tiercy, J.M.2
Boitard, C.3
-
14
-
-
0025898544
-
Implication of specific DQB1 alleles in genetic susceptibility and resistance by identification of IDDM siblings with novel HLA-DQB1 allele and unusual DR2 and DR1 haplotypes
-
Erlich HA, Griffith RL, Bugawan T.L., Ziegler R., Alper C, Eisenbarth G. Implication of specific DQB1 alleles in genetic susceptibility and resistance by identification of IDDM siblings with novel HLA-DQB1 allele and unusual DR2 and DR1 haplotypes. Diabetes 1991; 40:478-481
-
(1991)
Diabetes
, vol.40
, pp. 478-481
-
-
Erlich, H.A.1
Griffith, R.L.2
Bugawan, T.L.3
Ziegler, R.4
Alper, C.5
Eisenbarth, G.6
-
15
-
-
0031033610
-
Molecular modelling of HLA-DQ suggests a mechanism of resistance in type 1 diabetes
-
Hoover ML, Marta RT Molecular modelling of HLA-DQ suggests a mechanism of resistance in type 1 diabetes. Scand J Immunol 1997; 45:193-202
-
(1997)
Scand J Immunol
, vol.45
, pp. 193-202
-
-
Hoover, M.L.1
Marta, R.T.2
-
16
-
-
0028989040
-
∗0602 is associated with dominant protection from diabetes Even among islet cell antibody-positive first-degree relatives of patients with IDDM
-
∗0602 is associated with dominant protection from diabetes even among islet cell antibody-positive first-degree relatives of patients with IDDM. Diabetes 1995; 44:608-613
-
(1995)
Diabetes
, vol.44
, pp. 608-613
-
-
Pugliese, A.1
Gianani, R.2
Moromisato, R.3
-
19
-
-
33646456759
-
Specific human Leukocyte antigen DQ influence on expression of antiislet autoantibodies and progression to type 1 diabetes
-
Redondo MJ, Babu S, Zeidler A., et al.; Diabetes Prevention Trial Type 1 Study Group. Specific human leukocyte antigen DQ influence on expression of antiislet autoantibodies and progression to type 1 diabetes. J Clin Endocrinol Metab 2006; 91:1705-1713
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 1705-1713
-
-
Redondo, M.J.1
Babu, S.2
Zeidler, A.3
-
20
-
-
61549136296
-
The TrialNet natural history study of the development of type 1 diabetes: Objectives, design, and initial results
-
Mahon JL, Sosenko JM, Rafkin-Mervis L, et al.; TrialNet Natural History Committee; Type 1 Diabetes TrialNet Study Group. The TrialNet Natural History Study of the Development of Type 1 Diabetes: objectives, design, and initial results. Pediatr Diabetes 2009; 10:97-104
-
(2009)
Pediatr Diabetes
, vol.10
, pp. 97-104
-
-
Mahon, J.L.1
Sosenko, J.M.2
Rafkin-Mervis, L.3
-
21
-
-
84926338262
-
Classification and diagnosis of diabetes, sec. 2. In standards of medical care in diabetes - 2015
-
American Diabetes Association. Classification and diagnosis of diabetes, Sec. 2. In Standards of Medical Care in Diabetes - 2015. Diabetes Care 2015; 38(Suppl. 1):S8-S16
-
(2015)
Diabetes Care
, vol.38
, pp. S8-S16
-
-
-
22
-
-
84958651977
-
The development and utility of a novel scale that quantifies the glycemic progression toward type 1 diabetes over 6 months
-
Sosenko JM, Skyler JS, Beam C.A., et al.; Type 1 Diabetes TrialNet and Diabetes Prevention Trial-Type 1 Study Groups. The development and utility of a novel scale that quantifies the glycemic progression toward type 1 diabetes over 6 months. Diabetes Care 2015; 38:940-942
-
(2015)
Diabetes Care
, vol.38
, pp. 940-942
-
-
Sosenko, J.M.1
Skyler, J.S.2
Beam, C.A.3
-
23
-
-
77649244995
-
Trends of earlier and later responses of C-peptide to oral glucose challenges with progression to type 1 diabetes in diabetes prevention trial-type 1 participants
-
Sosenko JM, Palmer JP, Rafkin L.E., et al.; Diabetes Prevention Trial-Type 1 Study Group. Trends of earlier and later responses of C-peptide to oral glucose challenges with progression to type 1 diabetes in Diabetes Prevention Trial-Type 1 participants. Diabetes Care 2010; 33:620-625
-
(2010)
Diabetes Care
, vol.33
, pp. 620-625
-
-
Sosenko, J.M.1
Palmer, J.P.2
Rafkin, L.E.3
-
24
-
-
77954949830
-
Harmonization of glutamic acid decarboxylase and islet antigen-2 autoantibody assays for national institute of diabetes and digestive and kidney diseases consortia
-
Bonifacio E, Yu L, Williams A.K., et al. Harmonization of glutamic acid decarboxylase and islet antigen-2 autoantibody assays for National Institute of Diabetes and Digestive and Kidney Diseases consortia. J Clin Endocrinol Metab 2010; 95:3360-3367
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 3360-3367
-
-
Bonifacio, E.1
Yu, L.2
Williams, A.K.3
-
25
-
-
84856689949
-
Development of autoantibodies in the TrialNet natural history study
-
Vehik K, Beam CA, Mahon J.L., et al.; TrialNet Natural History Study Group. Development of autoantibodies in the TrialNet Natural History Study. Diabetes Care 2011; 34:1897-1901
-
(2011)
Diabetes Care
, vol.34
, pp. 1897-1901
-
-
Vehik, K.1
Beam, C.A.2
Mahon, J.L.3
-
26
-
-
36749011882
-
The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes
-
Wenzlau JM, Juhl K, Yu L., et al. The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes. Proc Natl Acad Sci U S A 2007; 104:17040-17045
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 17040-17045
-
-
Wenzlau, J.M.1
Juhl, K.2
Yu, L.3
-
27
-
-
84891821090
-
GAD65 autoantibodies detected by electrochemiluminescence assay identify high risk for type 1 diabetes
-
Miao D, Guyer KM, Dong F, et al GAD65 autoantibodies detected by electrochemiluminescence assay identify high risk for type 1 diabetes. Diabetes 2013; 62:4174-4178
-
(2013)
Diabetes
, vol.62
, pp. 4174-4178
-
-
Miao, D.1
Guyer, K.M.2
Dong, F.3
-
28
-
-
84886055195
-
Proinsulin/insulin autoantibodies measured with electrochemiluminescent assay are the earliest indicator of prediabetic islet autoimmunity
-
Yu L, Dong F, Miao D., Fouts AR, Wenzlau JM, Steck AK. Proinsulin/insulin autoantibodies measured with electrochemiluminescent assay are the earliest indicator of prediabetic islet autoimmunity. Diabetes Care 2013; 36:2266-2270
-
(2013)
Diabetes Care
, vol.36
, pp. 2266-2270
-
-
Yu, L.1
Dong, F.2
Miao, D.3
Fouts, A.R.4
Wenzlau, J.M.5
Steck, A.K.6
-
29
-
-
84922463345
-
Electrochemiluminescence assays for insulin and glutamic acid decarboxylase autoantibodies improve prediction of type 1 diabetes risk
-
Miao D, Steck AK, Zhang L, et al; Type 1 Diabetes TrialNet Study Group. Electrochemiluminescence assays for insulin and glutamic acid decarboxylase autoantibodies improve prediction of type 1 diabetes risk. Diabetes Technol Ther 2015; 17:119-127
-
(2015)
Diabetes Technol Ther
, vol.17
, pp. 119-127
-
-
Miao, D.1
Steck, A.K.2
Zhang, L.3
-
31
-
-
34547605312
-
T-cell responses to islet antigens improves detection of autoimmune diabetes and identifies patients with more severe beta-cell lesions in phenotypic type 2 diabetes
-
Goel A, Chiu H, Felton J., Palmer JP, Brooks-Worrell B. T-cell responses to islet antigens improves detection of autoimmune diabetes and identifies patients with more severe beta-cell lesions in phenotypic type 2 diabetes. Diabetes 2007; 56:2110-2115
-
(2007)
Diabetes
, vol.56
, pp. 2110-2115
-
-
Goel, A.1
Chiu, H.2
Felton, J.3
Palmer, J.P.4
Brooks-Worrell, B.5
-
32
-
-
44349193971
-
A risk score for type 1 diabetes derived from autoantibodypositive participants in the diabetes prevention trial-type 1
-
Sosenko JM, Krischer JP, Palmer J.P., et al.; Diabetes Prevention Trial-Type 1 Study Group. A risk score for type 1 diabetes derived from autoantibodypositive participants in the Diabetes Prevention Trial-Type 1. Diabetes Care 2008; 31:528-533
-
(2008)
Diabetes Care
, vol.31
, pp. 528-533
-
-
Sosenko, J.M.1
Krischer, J.P.2
Palmer, J.P.3
-
33
-
-
84861761425
-
Zinc transporter-8 autoantibodies improve prediction of type 1 diabetes in relatives positive for the standard biochemical autoantibodies
-
Yu L, Boulware DC, Beam C.A., et al.; Type 1 Diabetes TrialNet Study Group. Zinc transporter-8 autoantibodies improve prediction of type 1 diabetes in relatives positive for the standard biochemical autoantibodies. Diabetes Care 2012; 35:1213-1218
-
(2012)
Diabetes Care
, vol.35
, pp. 1213-1218
-
-
Yu, L.1
Boulware, D.C.2
Beam, C.A.3
-
34
-
-
84879114358
-
Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children
-
Ziegler AG, Rewers M, Simell O., et al. Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children. JAMA 2013; 309: 2473-2479
-
(2013)
JAMA
, vol.309
, pp. 2473-2479
-
-
Ziegler, A.G.1
Rewers, M.2
Simell, O.3
-
35
-
-
84947344265
-
Reactivity to N-terminally truncated GAD65(96-585) identifies GAD autoantibodies that are more closely associated with diabetes progression in relatives of patients with type 1 diabetes
-
Williams AJ, Lampasona V, Wyatt R., et al. Reactivity to N-terminally truncated GAD65(96-585) identifies GAD autoantibodies that are more closely associated with diabetes progression in relatives of patients with type 1 diabetes. Diabetes 2015; 64:3247-3252
-
(2015)
Diabetes
, vol.64
, pp. 3247-3252
-
-
Williams, A.J.1
Lampasona, V.2
Wyatt, R.3
-
36
-
-
84962919786
-
Detection of antibodies directed to the N-terminal region of GAD is dependent on assay format and contributes to differences in the specificity of GAD autoantibody assays for type 1 diabetes
-
Williams AJ, Lampasona V, Schlosser M., et al.; Participating Laboratories. Detection of antibodies directed to the N-terminal region of GAD is dependent on assay format and contributes to differences in the specificity of GAD autoantibody assays for type 1 diabetes. Diabetes 2015; 64:3239-3246
-
(2015)
Diabetes
, vol.64
, pp. 3239-3246
-
-
Participating Laboratories1
Williams, A.J.2
Lampasona, V.3
Schlosser, M.4
-
37
-
-
28444477379
-
∗0602 haplotype associated with attenuated protection from type 1 diabetes mellitus
-
∗0602 haplotype associated with attenuated protection from type 1 diabetes mellitus. Diabetologia 2005; 48:2540-2543
-
(2005)
Diabetologia
, vol.48
, pp. 2540-2543
-
-
Valdes, A.M.1
Thomson, G.2
Graham, J.3
-
38
-
-
67651021231
-
Overadjustment bias and unnecessary adjustment in epidemiologic studies
-
Schisterman EF, Cole SR, Platt RW Overadjustment bias and unnecessary adjustment in epidemiologic studies. Epidemiology 2009; 20:488-495
-
(2009)
Epidemiology
, vol.20
, pp. 488-495
-
-
Schisterman, E.F.1
Cole, S.R.2
Platt, R.W.3
-
39
-
-
84872716878
-
The multiple origins of type 1 diabetes
-
Pugliese A. The multiple origins of type 1 diabetes. Diabet Med 2013; 30: 135-146
-
(2013)
Diabet Med
, vol.30
, pp. 135-146
-
-
Pugliese, A.1
-
40
-
-
0030779118
-
A mechanism for the major histocompatibility complex-linked resistance to autoimmunity
-
Schmidt D, Verdaguer J, Averill N., Santamaria P. A mechanism for the major histocompatibility complex-linked resistance to autoimmunity. J Exp Med 1997; 186:1059-1075
-
(1997)
J Exp Med
, vol.186
, pp. 1059-1075
-
-
Schmidt, D.1
Verdaguer, J.2
Averill, N.3
Santamaria, P.4
-
41
-
-
80052276617
-
Functional consequences of HLA-DQ8 homozygosity versus heterozygosity for islet autoimmunity in type 1 diabetes
-
Eerligh P, van Lummel M, Zaldumbide A, et al Functional consequences of HLA-DQ8 homozygosity versus heterozygosity for islet autoimmunity in type 1 diabetes. Genes Immun 2011; 12:415-427
-
(2011)
Genes Immun
, vol.12
, pp. 415-427
-
-
Eerligh, P.1
Van Lummel, M.2
Zaldumbide, A.3
-
42
-
-
0027441931
-
Determinant capture as a possible mechanism of protection afforded by major histocompatibility complex class II molecules in autoimmune disease
-
Deng H, Apple R, Clare-Salzler M, et al. Determinant capture as a possible mechanism of protection afforded by major histocompatibility complex class II molecules in autoimmune disease. J Exp Med 1993; 178: 1675-1680
-
(1993)
J Exp Med
, vol.178
, pp. 1675-1680
-
-
Deng, H.1
Apple, R.2
Clare-Salzler, M.3
-
43
-
-
0036128080
-
Mutational analysis of critical residues determining antigen presentation and activation of HLA-DQ0602 restricted T-cell clones
-
Reichstetter S, Papadopoulos GK, Moustakas A.K., et al. Mutational analysis of critical residues determining antigen presentation and activation of HLA-DQ0602 restricted T-cell clones. Hum Immunol 2002; 63:185-193
-
(2002)
Hum Immunol
, vol.63
, pp. 185-193
-
-
Reichstetter, S.1
Papadopoulos, G.K.2
Moustakas, A.K.3
-
44
-
-
0032030625
-
∗0602, the class II MHC molecule associated with dominant protection in insulin-dependent diabetes mellitus
-
∗0602, the class II MHC molecule associated with dominant protection in insulin-dependent diabetes mellitus. J Immunol 1998; 160:2365-2373
-
(1998)
J Immunol
, vol.160
, pp. 2365-2373
-
-
Ettinger, R.A.1
Kwok, W.W.2
-
45
-
-
0032835668
-
Identification of peptides from autoantigens GAD65 and IA-2 that bind to HLA class II molecules predisposing to or protecting from type 1 diabetes
-
Harfouch-Hammoud E., Walk T, Otto H., et al. Identification of peptides from autoantigens GAD65 and IA-2 that bind to HLA class II molecules predisposing to or protecting from type 1 diabetes. Diabetes 1999; 48:1937-1947
-
(1999)
Diabetes
, vol.48
, pp. 1937-1947
-
-
Harfouch-Hammoud, E.1
Walk, T.2
Otto, H.3
-
46
-
-
0038632181
-
Promiscuous binding of proinsulin peptides to type 1 diabetes-permissive and - Protective HLA class II molecules
-
Astill TP, Ellis RJ, Arif S, Tree T.I., Peakman M. Promiscuous binding of proinsulin peptides to type 1 diabetes-permissive and - protective HLA class II molecules. Diabetologia 2003; 46:496-503
-
(2003)
Diabetologia
, vol.46
, pp. 496-503
-
-
Astill, T.P.1
Ellis, R.J.2
Arif, S.3
Tree, T.I.4
Peakman, M.5
-
47
-
-
84920381515
-
Cell-surface MHC density profiling reveals instability of autoimmunity-associated HLA
-
Miyadera H, Ohashi J, Lernmark Å, Kitamura T, Tokunaga K. Cell-surface MHC density profiling reveals instability of autoimmunity-associated HLA. J Clin Invest 2015; 125:275-291
-
(2015)
J Clin Invest
, vol.125
, pp. 275-291
-
-
Miyadera, H.1
Ohashi, J.2
Lernmark, A.3
Kitamura, T.4
Tokunaga, K.5
-
48
-
-
84962430639
-
Staging presymptomatic type 1 diabetes: A scientific statement of JDRF, the endocrine society, and the American diabetes association
-
Insel RA, Dunne JL, Atkinson M.A., et al. Staging presymptomatic type 1 diabetes: a scientific statement of JDRF, the Endocrine Society, and the American Diabetes Association. Diabetes Care 2015; 38:1964-1974
-
(2015)
Diabetes Care
, vol.38
, pp. 1964-1974
-
-
Insel, R.A.1
Dunne, J.L.2
Atkinson, M.A.3
|