Viral serine palmitoyltransferase induces metabolic switch in sphingolipid biosynthesis and is required for infection of a marine alga

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 13, 2016, Pages E1907-E1916

  Ziv, Carmit ^a   Malitsky, Sergey ^a   Othman, Alaa ^b,c   Ben Dor, Shifra ^a   Wei, Yu ^b   Zheng, Shuning ^a   Aharoni, Asaph ^a   Hornemann, Thorsten ^b   Vardi, Assaf ^a   Karl, David M ^d  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c UNIVERSITY OF LÜBECK   (Germany)

^d UNIVERSITY OF HAWAII   (United States)

Author keywords

Algal blooms; Emiliania huxelyi; Marine viruses; Serine palmitoyltransferase; Sphingolipids

Indexed keywords

CARBON; COENZYME A; GLYCOSPHINGOLIPID; SERINE PALMITOYLTRANSFERASE; SPHINGOLIPID; THERMOZYMOCIDIN; DNA VIRUS; VIRAL PROTEIN;

ALGA; ALGAL BLOOM; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; DOUBLE-STRANDED DNA VIRUS; EMILIANIA HUXLEYI; ENZYME ACTIVITY; ENZYME SPECIFICITY; GENE EXPRESSION; HOST PATHOGEN INTERACTION; MARINE SPECIES; METABOLISM; MICROSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEA; UPREGULATION; VIRUS GENOME; VIRUS INFECTION; VIRUS RELEASE; VIRUS REPLICATION; CHEMISTRY; EUTROPHICATION; GENE EXPRESSION REGULATION; GENETICS; HAPTOPHYTA; HYDROXYLATION; PATHOGENICITY; PLANT DISEASE; VIROLOGY;

DNA VIRUSES; EUTROPHICATION; GENE EXPRESSION REGULATION, VIRAL; GLYCOSPHINGOLIPIDS; HAPTOPHYTA; HOST-PATHOGEN INTERACTIONS; HYDROXYLATION; PLANT DISEASES; SERINE C-PALMITOYLTRANSFERASE; SPHINGOLIPIDS; VIRAL PROTEINS;

EID: 84962113317     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1523168113     Document Type: Article

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