메뉴 건너뛰기




Volumn 26, Issue 6, 2016, Pages 485-492

New medications for heart failure

Author keywords

Funny channel; Heart failure therapies; Ivabradine; Neprilysin; Sacubitril valsartan

Indexed keywords

IVABRADINE; MEMBRANE METALLOENDOPEPTIDASE; SACUBITRIL PLUS VALSARTAN; AMINOBUTYRIC ACID DERIVATIVE; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANTIARRHYTHMIC AGENT; BENZAZEPINE DERIVATIVE; CYCLIC NUCLEOTIDE GATED CHANNEL; PROTEINASE INHIBITOR; TETRAZOLE DERIVATIVE;

EID: 84962106603     PISSN: 10501738     EISSN: 18732615     Source Type: Journal    
DOI: 10.1016/j.tcm.2016.02.008     Document Type: Review
Times cited : (22)

References (40)
  • 1
    • 84872054233 scopus 로고    scopus 로고
    • AHA statistical update. Heart disease and stroke statistics—2013 update. A report from the American Heart Association
    • [1] Go, A.S., Mozaffarian, D., Roger, V.L., Benjamin, E.J., Berry, J.D., Borden, W.B., et al. AHA statistical update. Heart disease and stroke statistics—2013 update. A report from the American Heart Association. Circulation 127 (2013), e6–e245.
    • (2013) Circulation , vol.127 , pp. e6-e245
    • Go, A.S.1    Mozaffarian, D.2    Roger, V.L.3    Benjamin, E.J.4    Berry, J.D.5    Borden, W.B.6
  • 2
    • 79952444246 scopus 로고    scopus 로고
    • AHA policy statement. Forecasting the future of cardiovascular disease in the United States. A policy statement from the American Heart Association
    • [2] Heidenreich, P.A., Trogdon, J.G., Khavjou, O.A., Butler, J., Dracup, K., Ezekowitz, M.D., et al. AHA policy statement. Forecasting the future of cardiovascular disease in the United States. A policy statement from the American Heart Association. Circulation 123 (2011), 933–944.
    • (2011) Circulation , vol.123 , pp. 933-944
    • Heidenreich, P.A.1    Trogdon, J.G.2    Khavjou, O.A.3    Butler, J.4    Dracup, K.5    Ezekowitz, M.D.6
  • 3
    • 0033549290 scopus 로고    scopus 로고
    • Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in-Congestive Heart Failure (MERIT-HF)
    • [3] MERIT-HF Study Group, Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in-Congestive Heart Failure (MERIT-HF). Lancet 353 (1999), 2001–2007.
    • (1999) Lancet , vol.353 , pp. 2001-2007
    • MERIT-HF Study Group1
  • 4
    • 0037159310 scopus 로고    scopus 로고
    • Effect of carvedilol on the morbidity of patients with severe chronic heart failure: results of the Carvedilol Prospective Randomized Cumulative Survical (COPERNICUS) study
    • [4] Packer, M., Fowler, M.B., Roecker, E.B., Coats, A.J.S., Katus, H.A., Krum, H., et al. Effect of carvedilol on the morbidity of patients with severe chronic heart failure: results of the Carvedilol Prospective Randomized Cumulative Survical (COPERNICUS) study. Circulation 106 (2002), 2194–2199.
    • (2002) Circulation , vol.106 , pp. 2194-2199
    • Packer, M.1    Fowler, M.B.2    Roecker, E.B.3    Coats, A.J.S.4    Katus, H.A.5    Krum, H.6
  • 5
    • 85019316271 scopus 로고
    • Effects of enalapril on mortality in severe congestive heart failure
    • [5] The Consensus Trial Study Group, Effects of enalapril on mortality in severe congestive heart failure. N Engl J Med 316 (1987), 1429–1435.
    • (1987) N Engl J Med , vol.316 , pp. 1429-1435
    • The Consensus Trial Study Group1
  • 6
    • 0025913812 scopus 로고
    • Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure
    • [6] The SOLVD Investigators, Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. N Engl J Med 325 (1991), 293–302.
    • (1991) N Engl J Med , vol.325 , pp. 293-302
    • The SOLVD Investigators1
  • 7
    • 0033517302 scopus 로고    scopus 로고
    • The effects of spironolactone on morbidity and mortality in patients with severe heart failure
    • [7] Pitt, B., Zannad, F., Remme, W.J., Cody, R., Castaigne, A., Perez, A., et al. The effects of spironolactone on morbidity and mortality in patients with severe heart failure. N Engl J Med 341 (1999), 709–717.
    • (1999) N Engl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3    Cody, R.4    Castaigne, A.5    Perez, A.6
  • 8
    • 77956612624 scopus 로고    scopus 로고
    • Ivabradine and Outcomes in Chronic Heart Failure (SHIFT): a randomised placebo-controlled study
    • [8] Swedberg, K., Komajda, M., Bohm, M., Borer, J.S., Ford, I., Dubost-Brama, A., et al. Ivabradine and Outcomes in Chronic Heart Failure (SHIFT): a randomised placebo-controlled study. Lancet 376 (2010), 875–885.
    • (2010) Lancet , vol.376 , pp. 875-885
    • Swedberg, K.1    Komajda, M.2    Bohm, M.3    Borer, J.S.4    Ford, I.5    Dubost-Brama, A.6
  • 10
    • 77954056940 scopus 로고    scopus 로고
    • Renin–angiotensin–aldosterone system blockade for cardiovascular disease: current status
    • [10] Ma, T.K.W., Kam, K.K.H., Yan, B.P., Lam, Y., Renin–angiotensin–aldosterone system blockade for cardiovascular disease: current status. Br J Pharmacol 160 (2010), 1273–1292.
    • (2010) Br J Pharmacol , vol.160 , pp. 1273-1292
    • Ma, T.K.W.1    Kam, K.K.H.2    Yan, B.P.3    Lam, Y.4
  • 11
    • 84883565348 scopus 로고    scopus 로고
    • Adrenergic nervous sytem in heart failure: pathophysiology and therapy
    • [11] Lymperopoulous, A., Rengo, G., Koch, W.J., Adrenergic nervous sytem in heart failure: pathophysiology and therapy. Circ Res 113 (2013), 739–753.
    • (2013) Circ Res , vol.113 , pp. 739-753
    • Lymperopoulous, A.1    Rengo, G.2    Koch, W.J.3
  • 12
    • 0025770138 scopus 로고
    • A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure
    • [12] Cohn, J.N., Johnson, G., Ziesche, S., Cobb, F., Francis, G., Tristani, F., et al. A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure. N Engl J Med 325 (1991), 303–310.
    • (1991) N Engl J Med , vol.325 , pp. 303-310
    • Cohn, J.N.1    Johnson, G.2    Ziesche, S.3    Cobb, F.4    Francis, G.5    Tristani, F.6
  • 13
    • 84875444327 scopus 로고    scopus 로고
    • Incremental cost-effectiveness of guideline-directed medical therapies for heart failure
    • [13] Banka, G., Heidenreich, P.A., Fonarow, G.C., Incremental cost-effectiveness of guideline-directed medical therapies for heart failure. J Am Coll Cardiol 61 (2013), 1440–1446.
    • (2013) J Am Coll Cardiol , vol.61 , pp. 1440-1446
    • Banka, G.1    Heidenreich, P.A.2    Fonarow, G.C.3
  • 14
    • 84920538388 scopus 로고    scopus 로고
    • Long-term cardiovascular risks associated with an elevated heart rate: the Framingham heart study
    • [14] Ho, J.F., Larson, M.G., Ghorbani, A., Cheng, S., Coglianese, E.E., Vasan, R.S., et al. Long-term cardiovascular risks associated with an elevated heart rate: the Framingham heart study. J Am Heart Assoc, 3, 2014, e000668.
    • (2014) J Am Heart Assoc , vol.3 , pp. e000668
    • Ho, J.F.1    Larson, M.G.2    Ghorbani, A.3    Cheng, S.4    Coglianese, E.E.5    Vasan, R.S.6
  • 15
    • 79960152080 scopus 로고    scopus 로고
    • Resting cardiac energy metabolism is inversely associated with heart rate in healthy young men
    • [15] Fragasso, G., De Cobelli, F., Spoladore, R., Esposito, Salerno, A., Calori, G., et al. Resting cardiac energy metabolism is inversely associated with heart rate in healthy young men. Am Heart J 162 (2011), 136–141.
    • (2011) Am Heart J , vol.162 , pp. 136-141
    • Fragasso, G.1    De Cobelli, F.2    Spoladore, R.3    Esposito4    Salerno, A.5    Calori, G.6
  • 16
    • 84959099950 scopus 로고    scopus 로고
    • Heart rate or beta-blocker dose? Association with outcomes in ambulatory heart failure patients with systolic dysfunction: results from the HF-ACITON trial
    • [16] Fiuzat, M., Wojdyla, D., PIna, I., Adams, K., Whellan, D., O'Connor, C.M., Heart rate or beta-blocker dose? Association with outcomes in ambulatory heart failure patients with systolic dysfunction: results from the HF-ACITON trial. J Am Coll Cardiol Heart Fail 4 (2016), 109–115.
    • (2016) J Am Coll Cardiol Heart Fail , vol.4 , pp. 109-115
    • Fiuzat, M.1    Wojdyla, D.2    PIna, I.3    Adams, K.4    Whellan, D.5    O'Connor, C.M.6
  • 17
    • 3142776467 scopus 로고    scopus 로고
    • Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol or Metoprolol European Trial (COMET): randomised controlled trial
    • [17] Poole-Wilson, P.A., Swedberg, K., Cleland, J.G.F., Di Lenarda, A., et al. Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol or Metoprolol European Trial (COMET): randomised controlled trial. Lancet 362 (2003), 7–13.
    • (2003) Lancet , vol.362 , pp. 7-13
    • Poole-Wilson, P.A.1    Swedberg, K.2    Cleland, J.G.F.3    Di Lenarda, A.4
  • 18
    • 66649100010 scopus 로고    scopus 로고
    • Meta-analysis: β-blocker dose, heart rate reduction, and death in patients with heart failure
    • [18] McAlister, F.A., Wiebe, N., Ezekowtiz, J.A., Leung, A.A., Armstrong, PW, Meta-analysis: β-blocker dose, heart rate reduction, and death in patients with heart failure. Ann Intern Med 150 (2009), 784–794.
    • (2009) Ann Intern Med , vol.150 , pp. 784-794
    • McAlister, F.A.1    Wiebe, N.2    Ezekowtiz, J.A.3    Leung, A.A.4    Armstrong, P.W.5
  • 19
    • 70350513886 scopus 로고    scopus 로고
    • The sympathetic nervous system in heart failure: physiology, pathophysiology, and clinical implications
    • [19] Triposkiadis, F., Karayannis, G., Giamouzis, G., Skoularigis, J., Louridas, G., Butler, J., The sympathetic nervous system in heart failure: physiology, pathophysiology, and clinical implications. J Am Coll Cardiol 54 (2009), 1747–1762.
    • (2009) J Am Coll Cardiol , vol.54 , pp. 1747-1762
    • Triposkiadis, F.1    Karayannis, G.2    Giamouzis, G.3    Skoularigis, J.4    Louridas, G.5    Butler, J.6
  • 20
    • 77649123846 scopus 로고    scopus 로고
    • The role of the funny current in pacemaker activity
    • [20] DiFrancesco, D., The role of the funny current in pacemaker activity. Circ Res 106 (2010), 434–446.
    • (2010) Circ Res , vol.106 , pp. 434-446
    • DiFrancesco, D.1
  • 21
    • 22744450757 scopus 로고    scopus 로고
    • f current and its inhibition by heart rate-reducing agents
    • f current and its inhibition by heart rate-reducing agents. Curr Med Res Opin 21 (2005), 1115–1122.
    • (2005) Curr Med Res Opin , vol.21 , pp. 1115-1122
    • DiFrancesco, D.1
  • 22
    • 50649109186 scopus 로고    scopus 로고
    • BEAUTIFUL Investigators. Ivabradine for Patients With Stable Coronary Artery Disease and Left-Ventricular Systolic Dysfunction (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial
    • [22] Fox, K., Ford, I., Steg, P.G., Tendera, M., Ferrari, R., BEAUTIFUL Investigators. Ivabradine for Patients With Stable Coronary Artery Disease and Left-Ventricular Systolic Dysfunction (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial. Lancet 372 (2008), 807–816.
    • (2008) Lancet , vol.372 , pp. 807-816
    • Fox, K.1    Ford, I.2    Steg, P.G.3    Tendera, M.4    Ferrari, R.5
  • 23
    • 84885845957 scopus 로고    scopus 로고
    • 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines
    • [23] Yancy, C.W., Jessup, M., Bozkurt, B., Butler, J., Casey, D.E., Drazner, M.H., et al. 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines. Circulation 128 (2013), e240–e327.
    • (2013) Circulation , vol.128 , pp. e240-e327
    • Yancy, C.W.1    Jessup, M.2    Bozkurt, B.3    Butler, J.4    Casey, D.E.5    Drazner, M.H.6
  • 24
    • 84861527957 scopus 로고    scopus 로고
    • Effects on outcomes of heart rate reduction by ivabradine in patients with congestive heart failure: is there an influence of beta-blocker dose?
    • [24] Swedberg, K., Komajda, M., Bohm, M., Borer, J., Robertson, M., Tavazzi, L., et al. Effects on outcomes of heart rate reduction by ivabradine in patients with congestive heart failure: is there an influence of beta-blocker dose?. J Am Coll Cardiol 59 (2012), 1938–1945.
    • (2012) J Am Coll Cardiol , vol.59 , pp. 1938-1945
    • Swedberg, K.1    Komajda, M.2    Bohm, M.3    Borer, J.4    Robertson, M.5    Tavazzi, L.6
  • 25
    • 77956618692 scopus 로고    scopus 로고
    • Heart rate as a risk factor in chronic heart failure (SHIFT): the association between heart rate and outcomes in a randomised placebo-controlled trial
    • [25] Bohm, M., Swedberg, K., Komajda, M., Borer, J.S., Ford, I., Dubost-Brama, A., et al. Heart rate as a risk factor in chronic heart failure (SHIFT): the association between heart rate and outcomes in a randomised placebo-controlled trial. Lancet 376 (2010), 886–894.
    • (2010) Lancet , vol.376 , pp. 886-894
    • Bohm, M.1    Swedberg, K.2    Komajda, M.3    Borer, J.S.4    Ford, I.5    Dubost-Brama, A.6
  • 26
    • 84907424112 scopus 로고    scopus 로고
    • Ivabradine in stable coronary artery disease without clinical heart failure
    • [26] Fox, K., Ford, I., Steg, P.G., Tardif, J., et al. Ivabradine in stable coronary artery disease without clinical heart failure. N Engl J Med 371 (2014), 1091–1099.
    • (2014) N Engl J Med , vol.371 , pp. 1091-1099
    • Fox, K.1    Ford, I.2    Steg, P.G.3    Tardif, J.4
  • 27
    • 80054742115 scopus 로고    scopus 로고
    • Effects of selective heart rate reduction with ivabradine on left ventricular remodeling and function: results from the SHIFT echocardiography substudy
    • [27] Tardif, J., O'Meara, E., Komajda, M., Bohm, M., Borer, J.S., Ford, I., et al. Effects of selective heart rate reduction with ivabradine on left ventricular remodeling and function: results from the SHIFT echocardiography substudy. Eur Heart J 32 (2011), 2507–2515.
    • (2011) Eur Heart J , vol.32 , pp. 2507-2515
    • Tardif, J.1    O'Meara, E.2    Komajda, M.3    Bohm, M.4    Borer, J.S.5    Ford, I.6
  • 28
    • 80054070561 scopus 로고    scopus 로고
    • Heart rate reduction with ivabradine and health related quality of life in patients with chronic heart failure: results from the SHIFT study
    • [28] Ekman, I., Chassany, O., Komajda, M., Bohm, M., Borer, J.S., Ford, I., et al. Heart rate reduction with ivabradine and health related quality of life in patients with chronic heart failure: results from the SHIFT study. Eur Heart J 32 (2011), 2395–2404.
    • (2011) Eur Heart J , vol.32 , pp. 2395-2404
    • Ekman, I.1    Chassany, O.2    Komajda, M.3    Bohm, M.4    Borer, J.S.5    Ford, I.6
  • 30
    • 3042813668 scopus 로고    scopus 로고
    • Implications of the natriuretic peptide system in the pathogenesis of heart failure: diagnostic and therapeutic importance
    • [30] Abassi, Z., Karram, T., Ellaham, S., Winaver, J., Hoffman, A., Implications of the natriuretic peptide system in the pathogenesis of heart failure: diagnostic and therapeutic importance. Pharmacol Ther 102 (2004), 223–241.
    • (2004) Pharmacol Ther , vol.102 , pp. 223-241
    • Abassi, Z.1    Karram, T.2    Ellaham, S.3    Winaver, J.4    Hoffman, A.5
  • 31
    • 0031777423 scopus 로고    scopus 로고
    • Function effects of endogenous bradykinin in congestive heart failure
    • [31] Cheng, C., Onishi, K., Ohte, N., Suzuki, M., Little, W., Function effects of endogenous bradykinin in congestive heart failure. J Am Coll Cardiol 31 (1998), 1679–1686.
    • (1998) J Am Coll Cardiol , vol.31 , pp. 1679-1686
    • Cheng, C.1    Onishi, K.2    Ohte, N.3    Suzuki, M.4    Little, W.5
  • 32
    • 0037143601 scopus 로고    scopus 로고
    • Comparison of omapatrilat and enalapril in patients with chronic heart failure: the Ompapatrilat Versus Enalapril Randomized Trial of Utility in Reducing Events (OVERTURE)
    • [32] Packer, M., Califf, R.M., Konstam, M.A., Krum, H., McMurray, J.J., Roleau, J., et al. Comparison of omapatrilat and enalapril in patients with chronic heart failure: the Ompapatrilat Versus Enalapril Randomized Trial of Utility in Reducing Events (OVERTURE). Circulation 106 (2002), 920–926.
    • (2002) Circulation , vol.106 , pp. 920-926
    • Packer, M.1    Califf, R.M.2    Konstam, M.A.3    Krum, H.4    McMurray, J.J.5    Roleau, J.6
  • 33
    • 1642452758 scopus 로고    scopus 로고
    • Omapatrilat and enalapril in patients with hypertension: the Omapatrilat Cardiovascular Treatment vs. Enalapril (OCTAVE) trial
    • [33] Kostis, J.B., Packer, M., Black, H.R., Schmieder, R., Henry, D., Levy, E., Omapatrilat and enalapril in patients with hypertension: the Omapatrilat Cardiovascular Treatment vs. Enalapril (OCTAVE) trial. Am J Hypertens 17 (2004), 103–111.
    • (2004) Am J Hypertens , vol.17 , pp. 103-111
    • Kostis, J.B.1    Packer, M.2    Black, H.R.3    Schmieder, R.4    Henry, D.5    Levy, E.6
  • 34
    • 77956817833 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of LCZ696, a novel dual-acting angiotensin receptor-neprilysin inhibitor (ARNi)
    • [34] Gu, J., Noe, A., Chandra, P., Al-Fayoumi, S., Lingueros-Saylan, M., Sarangapani, R., et al. Pharmacokinetics and pharmacodynamics of LCZ696, a novel dual-acting angiotensin receptor-neprilysin inhibitor (ARNi). J Clin Pharmacol 50 (2010), 401–414.
    • (2010) J Clin Pharmacol , vol.50 , pp. 401-414
    • Gu, J.1    Noe, A.2    Chandra, P.3    Al-Fayoumi, S.4    Lingueros-Saylan, M.5    Sarangapani, R.6
  • 36
    • 0035818884 scopus 로고    scopus 로고
    • A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure
    • [36] Cohn, J.N., Tognoni, G., for the Valsartan Heart Failure Trial Investigators, A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. N Engl J Med 345 (2001), 1667–1675.
    • (2001) N Engl J Med , vol.345 , pp. 1667-1675
    • Cohn, J.N.1    Tognoni, G.2    for the Valsartan Heart Failure Trial Investigators3
  • 37
    • 2642616191 scopus 로고    scopus 로고
    • Run-in periods in randomized trials: implications for the application of results in clinical practice
    • [37] Pablos-Mendez, A., Barr, G., Shea, A., Run-in periods in randomized trials: implications for the application of results in clinical practice. J Am Med Assoc 279 (1998), 222–225.
    • (1998) J Am Med Assoc , vol.279 , pp. 222-225
    • Pablos-Mendez, A.1    Barr, G.2    Shea, A.3
  • 38
    • 84924243546 scopus 로고    scopus 로고
    • Angiotensin receptor neprilysin inhibition compared with enalapril on the risk of clinical progression in surviving patients with heart failure
    • [38] Packer, M., McMurray, J.J., Desai, A.S., Gong, J., Lefkowitz, M.P., Rizkala, A.R., et al. Angiotensin receptor neprilysin inhibition compared with enalapril on the risk of clinical progression in surviving patients with heart failure. Circulation 131 (2005), 54–61.
    • (2005) Circulation , vol.131 , pp. 54-61
    • Packer, M.1    McMurray, J.J.2    Desai, A.S.3    Gong, J.4    Lefkowitz, M.P.5    Rizkala, A.R.6
  • 39
    • 1242295182 scopus 로고    scopus 로고
    • Predischarge B-type natriuretic peptide assay for identifying patients at high risk of re-admission after decompensated heart failure
    • [39] Logeart, D., Thabut, G., Jourdain, P., Chavelas, C., Beyne, P., Beauvais, F., et al. Predischarge B-type natriuretic peptide assay for identifying patients at high risk of re-admission after decompensated heart failure. J Am Coll Cardiol 43 (2004), 635–641.
    • (2004) J Am Coll Cardiol , vol.43 , pp. 635-641
    • Logeart, D.1    Thabut, G.2    Jourdain, P.3    Chavelas, C.4    Beyne, P.5    Beauvais, F.6
  • 40
    • 84867745957 scopus 로고    scopus 로고
    • The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double-blind randomized controlled trial
    • [40] Solomon, S.D., Zile, M., Pieske, B., Voors, A., Shah, A., Kraigher-Krainer, E., et al. The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double-blind randomized controlled trial. Lancet 380 (2012), 1387–1395.
    • (2012) Lancet , vol.380 , pp. 1387-1395
    • Solomon, S.D.1    Zile, M.2    Pieske, B.3    Voors, A.4    Shah, A.5    Kraigher-Krainer, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.