Fluorescence Monitoring of the Oxidative Repair of DNA Alkylation Damage by ALKBH3, a Prostate Cancer Marker

Journal of the American Chemical Society

Volumn 138, Issue 11, 2016, Pages 3647-3650

  Beharry, Andrew A ^a   Lacoste, Sandrine ^b   O'Connor, Timothy R ^b   Kool, Eric T ^a  

^a STANFORD UNIVERSITY   (United States)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIAGNOSIS; DISEASES; ENZYMES; FLUORESCENCE; PROBES; QUENCHING; REPAIR; UROLOGY;

DIAGNOSTIC MARKERS; DNA ALKYLATIONS; ENZYME INHIBITORS; ENZYME SUBSTRATES; FLUORESCENCE QUENCHING; FLUOROGENIC PROBES; MEASUREMENTS OF; PROSTATE CANCERS;

ENZYME ACTIVITY;

1 METHYLADENINE; ADENINE; ALKBH3 ENZYME; ALKYL GROUP; DEOXYADENOSINE DERIVATIVE; ENZYME; PERYLENE; PYRENE; UNCLASSIFIED DRUG; 1-METHYLADENINE; ALKBH3 PROTEIN, HUMAN; ALKYLATING AGENT; ALPHA KETOGLUTARATE DEPENDENT DIOXYGENASE ALKB HOMOLOG 3; FLUORESCENT DYE; TUMOR MARKER;

ABSORPTION; ANIMAL CELL; ARTICLE; CYTOSOL; DNA ALKYLATION; DNA DAMAGE; EMBRYO; ENZYME ACTIVITY; FLOW CYTOMETRY; FLUORESCENCE; GENETIC BACKGROUND; IN VITRO STUDY; INHIBITION CONSTANT; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MICROSCOPY; MOUSE; NONHUMAN; PH; QUANTUM YIELD; SYNTHESIS; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; ENZYMOLOGY; GENETICS; HUMAN; KINETICS; MALE; METABOLISM; OXIDATION REDUCTION REACTION; PROSTATIC NEOPLASMS; SPECTROFLUOROMETRY;

ADENINE; ALKB HOMOLOG 3, ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE; ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; BIOMARKERS, TUMOR; DNA DAMAGE; FLUORESCENT DYES; HUMANS; KINETICS; MALE; MICE; OXIDATION-REDUCTION; PROSTATIC NEOPLASMS; SPECTROMETRY, FLUORESCENCE;

EID: 84962050627     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.6b00986     Document Type: Article

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