The vitamin D receptor (VDR) gene rs11568820 variant is associated with type 2 diabetes and impaired insulin secretion in Italian adult subjects, and associates with increased cardio-metabolic risk in children

Nutrition, Metabolism and Cardiovascular Diseases

Volumn 26, Issue 5, 2016, Pages 407-413

  Sentinelli, F ^a   Bertoccini, L ^a   Barchetta, I ^c   Capoccia, D ^a   Incani, M ^b   Pani, M G ^b   Loche, S ^d   Angelico, F ^c   Arca, M ^c   Morini, S ^e   Manconi, E ^b   Lenzi, A ^a   Cossu, E ^b   Leonetti, F ^a   Baroni, M G ^a,b   Cavallo, M G ^c  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF CAGLIARI   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d Osp Regionale per le Microcitemie   (Italy)

^e UNIVERSITY CAMPUS BIO MEDICO   (Italy)

Author keywords

Insulin secretion; Insulin sensitivity; SNP; VDR gene

Indexed keywords

GLUCOSE; INSULIN; VITAMIN D; VITAMIN D RECEPTOR; BIOLOGICAL MARKER; CALCITRIOL RECEPTOR; GLUCOSE BLOOD LEVEL; VDR PROTEIN, HUMAN;

ARTICLE; CARDIOMETABOLIC RISK; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE; GENETIC VARIABILITY; GENOTYPE; HUMAN; INSULIN RELEASE; INSULIN RESISTANCE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; VDR GENE; ADOLESCENT; ADULT; BLOOD; CASE CONTROL STUDY; CHI SQUARE DISTRIBUTION; CHILD; CROSS-SECTIONAL STUDY; DIABETES MELLITUS, TYPE 2; GENE FREQUENCY; GENETIC ASSOCIATION STUDY; GENETIC PREDISPOSITION; GENETICS; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; HETEROZYGOTE; HOMOZYGOTE; ITALY; METABOLIC SYNDROME X; METABOLISM; MIDDLE AGED; ODDS RATIO; ONSET AGE; PEDIATRIC OBESITY; PHENOTYPE; RISK FACTOR; SECRETION (PROCESS); STATISTICAL MODEL;

ADOLESCENT; ADULT; AGE OF ONSET; BIOMARKERS; BLOOD GLUCOSE; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; CHILD; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GLUCOSE TOLERANCE TEST; HETEROZYGOTE; HOMOZYGOTE; HUMANS; INSULIN; INSULIN RESISTANCE; ITALY; LINEAR MODELS; LOGISTIC MODELS; MALE; METABOLIC SYNDROME X; MIDDLE AGED; ODDS RATIO; PEDIATRIC OBESITY; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, CALCITRIOL; RISK FACTORS;

EID: 84961955689     PISSN: 09394753     EISSN: 15903729     Source Type: Journal    
DOI: 10.1016/j.numecd.2016.02.004     Document Type: Article

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