Vitamin D receptor gene polymorphisms and susceptibility to type 1 diabetes in Crete, Greece

Clinical Immunology

Volumn 133, Issue 2, 2009, Pages 276-281

  Panierakis, Charalambos ^a   Goulielmos, George ^a   Mamoulakis, Dimitris ^a   Petraki, Eleni ^a   Papavasiliou, Efstathios ^a   Galanakis, Emmanouil ^a  

^a UNIVERSITY OF CRETE   (Greece)

Author keywords

Crete; Genetic susceptibility; Single nucleotide polymorphism; Type 1 diabetes; Vitamin D receptor

Indexed keywords

VITAMIN D RECEPTOR;

ALLELE; APA1 GENE; ARTICLE; BSML GENE; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; FEMALE; FOKL GENE; GENE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; GREECE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RECEPTOR GENE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK REDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; TAQ1 GENE; VDR GENE;

CHILD; DIABETES MELLITUS, TYPE 1; FEMALE; GENE FREQUENCY; GENOTYPE; GREECE; HAPLOTYPES; HUMANS; MALE; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; PREVALENCE; RECEPTORS, CALCITRIOL;

EID: 70349770528     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2009.08.004     Document Type: Article

References (39)

1. Uitterlinden A.G., Fang Y., Van Meurs J.B., Pols H.A., and Van Leeuwen J.P. Genetics and biology of vitamin D receptor polymorphisms. Gene 338 (2004) 143-156
2. Mathieu C., Waer M., Laureys J., Rutgeerts O., and Bouillon R. Prevention of autoimmune diabetes in NOD mice by 1,25 dihydroxyvitamin D3. Diabetologia 37 (1994) 552-558
3. The EURODIAB Substudy 2 Study Group. Vitamin D supplement in early childhood and risk for Type I (insulin-dependent) diabetes mellitus. Diabetologia 42 (1999) 51-54
4. Hypponen E., Laara E., Reunanen A., Jarvelin M.R., and Virtanen S.M. Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study. Lancet 358 (2001) 1500-1503
5. Fronczak C.M., Baron A.E., and Chase H.P. In utero dietary exposures and risk of islet autoimmunity in children. Diabetes Care 26 (2003) 3237-3242
6. Valdivielso J.M., and Fernandez E. Vitamin D receptor polymorphisms and diseases. Clin. Chim. Acta 371 (2006) 1-12
7. McDermott M.F., Ramachandran A., and Ogunkolade B.W. Allelic variation in the vitamin D receptor influences susceptibility to IDDM in Indian Asians. Diabetologia 40 (1997) 971-975
8. Motohashi Y., Yamada S., and Yanagawa T. Vitamin D receptor gene polymorphism affects onset pattern of type 1 diabetes. J. Clin. Endocrinol. Metab. 88 (2003) 3137-3140
9. Turpeinen H., Hermann R., and Vaara S. Vitamin D receptor polymorphisms: no association with type 1 diabetes in the Finnish population. Eur. J. Endocrinol. 149 (2003) 591-596
10. Lemos M.C., Fagulha A., Coutinho E., Gomes L., Bastos M., Barros L., Carrilho F., Geraldes E., Regateiro F.J., and Carvalheiro M. Lack of association of vitamin D receptor gene polymorphisms with susceptibility to type 1 diabetes mellitus in the Portuguese population. Hum. Immunol. 69 (2008) 134-138
11. Ban Y., Taniyama M., and Yanagawa T. Vitamin D receptor initiation codon polymorphism influences genetic susceptibility to type 1 diabetes mellitus in the Japanese population. BMC Med. Genet. 2 (2001) 7
12. Ponsonby A.L., Pezic A., Ellis J., Morley R., Cameron F., Carlin J., and Dwyer T. Variation in associations between allelic variants of the vitamin D receptor gene and onset of type 1 diabetes mellitus by ambient winter ultraviolet radiation levels: a meta-regression analysis. Am. J. Epidemiol. 168 (2008) 358-365
13. Mamoulakis D., Galanakis E., Bicouvarakis S., Paraskakis E., and Sbyrakis S. Epidemiology of childhood type I diabetes in Crete, 1990-2001. Acta Paediatr. 92 (2003) 737-739
14. Tzima N., Pitsavos C., Panagiotakos D.B., Skoumas J., Zampelas A., Chrysohoou C., and Stefanadis C. Mediterranean diet and insulin sensitivity, lipid profile and blood pressure levels, in overweight and obese people; the Attica study. Lipids Health Dis. 6 (2007) 22
15. Challa A., Ntourntoufi A., Cholevas V., Bitsori M., Galanakis E., and Andronikou S. Breastfeeding and vitamin D status in Greece during the first 6 months of life. Eur. J. Pediatr. 164 (2005) 724-729
16. American Diabetes Association. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 26 Suppl. 1 (2003) S5-S20
17. Guo S.W., Magnuson V.L., and Schiller J.J. Meta-analysis of vitamin D receptor polymorphisms and type 1 diabetes: a HuGE review of genetic association studies. Am. J. Epidemiol. 164 (2006) 711-724
18. Gyorffy B., Vasarhelyi B., and Krikovszky D. Gender-specific association of vitamin D receptor polymorphism combinations with type 1 diabetes mellitus. Eur. J. Endocrinol. 147 (2002) 803-808
19. Chang T.J., Lei H.H., and Yeh J.I. Vitamin D receptor gene polymorphisms influence susceptibility to type 1 diabetes mellitus in the Taiwanese population. Clin. Endocrinol. (Oxf) 52 (2000) 575-580
20. Pani M.A., Knapp M., and Donner H. Vitamin D receptor allele combinations influence genetic susceptibility to type 1 diabetes in Germans. Diabetes 49 (2000) 504-507
21. Fassbender W.J., Goertz B., and Weismuller K. VDR gene polymorphisms are overrepresented in German patients with type 1 diabetes compared to healthy controls without effect on biochemical parameters of bone metabolism. Horm. Metab. Res. 34 (2002) 330-337
22. Ramos-Lopez E., Jansen T., and Ivaskevicius V. Protection from type 1 diabetes by vitamin D receptor haplotypes. Ann. N.Y. Acad. Sci. 1079 (2006) 327-334
23. Yokota I., Satomura S., and Kitamura S. Association between vitamin D receptor genotype and age of onset in juvenile Japanese patients with type 1 diabetes. Diabetes Care 25 (2002) 1244
24. Skrabic V., Zemunik T., Situm M., and Terzic J. Vitamin D receptor polymorphism and susceptibility to type 1 diabetes in the Dalmatian population. Diabetes Res. Clin. Pract. 59 (2003) 31-35
25. Zemunik T., Skrabic V., and Boraska V. FokI polymorphism, vitamin D receptor, and interleukin-1 receptor haplotypes are associated with type 1 diabetes in the Dalmatian population. J. Mol. Diagn. 7 (2005) 600-604
26. Audi L., Marti G., and Esteban C. VDR gene polymorphism at exon 2 start codon (FokI) may have influenced Type 1 diabetes mellitus susceptibility in two Spanish populations. Diabet. Med. 21 (2004) 393-394
27. Garcia D., Angel B., and Carrasco E. VDR polymorphisms influence the immune response in type 1 diabetic children from Santiago, Chile. Diabetes Res. Clin. Pract. 77 (2007) 134-140
28. Ogunkolade B.W., Boucher B.J., Prahl J.M., Bustin S.A., Burrin J.M., Noonan K., North B.V., Mannan N., McDermott M.F., DeLuca H.F., and Hitman G.A. Vitamin D receptor (VDR) mRNA and VDR protein levels in relation to vitamin D status, insulin secretory capacity, and VDR genotype in Bangladeshi Asians. Diabetes 51 (2002) 2294-2300
29. Guja C., Marshall S., and Welsh K. The study of CTLA-4 and vitamin D receptor polymorphisms in the Romanian type 1 diabetes population. J. Cell Mol. Med. 6 (2002) 75-81
30. Angel B., Santos J.L., Carrasco E., Albala C., and Pérez-Bravo F. Vitamin D receptor polymorphism and susceptibility to type 1 diabetes in Chilean subjects: a case-parent study. Eur. J. Epidemiol. 19 (2004) 1085-1087
31. Bianco M.G., Minicucci L., and Calevo M.G. Vitamin D receptor polymorphisms: are they really associated with type 1 diabetes. Eur. J. Endocrinol. 151 (2004) 641-642
32. San-Pedro J.I., Bilbao J.R., and Perez de Nanclares G. Heterogeneity of vitamin D receptor gene association with celiac disease and type 1 diabetes mellitus. Autoimmunity 38 (2005) 439-444
33. Nejentsev S., Cooper J.D., and Godfrey L. Analysis of the vitamin D receptor gene sequence variants in type 1 diabetes. Diabetes 53 (2004) 2709-2712
34. Jurutka P.W., Remus L.S., Whitfield G.K., Thompson P.D., Hsieh J.C., Zitzer H., Tavakkoli P., Galligan M.A., Dang H.T., Haussler C.A., and Haussler M.R. The polymorphic N terminus in human vitamin D receptor isoforms influences transcriptional activity by modulating interaction with transcription factor IIB. Mol. Endocrinol. 14 (2000) 401-420
35. Obi-Tabot E.T., Tian X.Q., Chen T.C., and Holick M.F. A human skin equivalent model that mimics the photoproduction of vitamin D3 in human skin. In Vitro Cell Dev. Biol. Anim. 36 (2000) 201-204
36. van Etten E., Verlinden L., Giulietti A., Ramos-Lopez E., Branisteanu D.D., Ferreira G.B., Overbergh L., Verstuyf A., Bouillon R., Roep B.O., Badenhoop K., and Mathieu C. The vitamin D receptor gene FokI polymorphism: functional impact on the immune system. Eur. J. Immunol. 37 (2007) 395-405
37. Shimada A., Kanazawa Y., Motohashi Y., Yamada S., Maruyama T., Ikegami H., Awata T., Kawasaki E., Kobayashi T., Nakanishi K., Kawabata Y., Kurihara S., Uga M., and Tanaka S. Japanese Study Group on Type 1 Diabetes Genetics, Evidence for association between vitamin D receptor BsmI polymorphism and type 1 diabetes in Japanese. J. Autoimmun. 30 (2008) 207-211
38. Penna G., and Adorini L. 1 Alpha, 25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation. J. Immunol. 164 (2000) 2405-2411
39. Panierakis C., Goulielmos G., Mamoulakis D., Maraki S., Papavasiliou E., and Galanakis E. Staphylococcus aureus nasal carriage might be associated with vitamin D receptor polymorphisms in type 1 diabetes. Int. J. Infect Dis. (2009 May 1) [Electronic publication ahead of print]