Near Infrared-Guided Smart Nanocarriers for MicroRNA-Controlled Release of Doxorubicin/siRNA with Intracellular ATP as Fuel

ACS Nano

Volumn 10, Issue 3, 2016, Pages 3637-3647

  Zhang, Penghui ^a   Wang, Chen ^a   Zhao, Jingjing ^a   Xiao, Anqi ^a   Shen, Qi ^a   Li, Linting ^a   Li, Jianxin ^a   Zhang, Junfeng ^a   Min, Qianhao ^a   Chen, Jiangning ^a   Chen, Hong Yuan ^a   Zhu, Jun Jie ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

aptamer; DNA nanomachine; drug delivery; microRNA; smart nanocarriers

Indexed keywords

CARDIOVASCULAR SYSTEM; CELL CULTURE; CELL DEATH; CHEMOTHERAPY; CYTOLOGY; DISEASE CONTROL; DNA; DRUG DELIVERY; FUNCTIONAL POLYMERS; GENE ENCODING; GENE EXPRESSION; GENE THERAPY; GENES; IRRADIATION; MOLECULAR BIOLOGY; NANORODS; NANOSTRUCTURED MATERIALS; NANOTECHNOLOGY; POLYMERS; RNA; TUMORS;

APTAMERS; CASCADE AMPLIFICATION; DNA NANOMACHINE; MICRORNAS; NANO-CARRIERS; PHOTO-THERMAL CONVERSIONS; RECEPTOR-MEDIATED ENDOCYTOSIS; TEMPERATURE-SENSITIVE POLYMERS;

INFRARED DEVICES;

ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC ANTIBIOTIC; DELAYED RELEASE FORMULATION; DNA; DOXORUBICIN; MICRORNA; SMALL INTERFERING RNA;

ANIMAL; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG DELIVERY SYSTEM; FEMALE; FLUORESCENCE IMAGING; HUMAN; METABOLISM; MOUSE; NEOPLASMS; NIH 3T3 CELL LINE; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE, TUMOR; DELAYED-ACTION PREPARATIONS; DNA; DOXORUBICIN; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; MICE; MICE, NUDE; MICRORNAS; NEOPLASMS; NIH 3T3 CELLS; OPTICAL IMAGING; RNA, SMALL INTERFERING;

EID: 84961891792     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.5b08145     Document Type: Article

References (47)

1. Leung, S. J.; Romanowski, M. NIR-Activated Content Release from Plasmon Resonant Liposomes for Probing Single-Cell Responses ACS Nano 2012, 6, 9383-9391 10.1021/nn304434a
2. Hong, B. J.; Chipre, A. J.; Nguyen, S. T. Acid-Degradable Polymer-Caged Lipoplex (PCL) Platform for siRNA Delivery: Facile Cellular Triggered Release of siRNA J. Am. Chem. Soc. 2013, 135, 17655-17658 10.1021/ja404491r
3. Li, W.; Wang, J.; Ren, J.; Qu, X. Near-Infrared- and pH-Responsive System for Reversible Cell Adhesion Using Graphene/Gold Nanorods Functionalized with i-motif DNA Angew. Chem., Int. Ed. 2013, 52, 6726-6730 10.1002/anie.201302048
4. Nam, J.; La, W.-G.; Hwang, S.; Ha, Y. S.; Park, N.; Won, N.; Jung, S.; Bhang, S. H.; Ma, Y.-J.; Cho, Y.-M. et al. pH-Responsive Assembly of Gold Nanoparticles and "Spatiotemporally Concerted" Drug Release for Synergistic Cancer Therapy ACS Nano 2013, 7, 3388-3402 10.1021/nn400223a
5. Zhang, Z.; Balogh, D.; Wang, F.; Sung, S. Y.; Nechushtai, R.; Willner, I. Biocatalytic Release of an Anticancer Drug from Nucleic-Acids-Capped Mesoporous SiO2 Using DNA or Molecular Biomarkers as Triggering Stimuli ACS Nano 2013, 7, 8455-8468 10.1021/nn403772j
6. Tarn, D.; Ashley, C. E.; Xue, M.; Carnes, E. C.; Zink, J. I.; Brinker, C. J. Mesoporous Silica Nanoparticle Nanocarriers: Biofunctionality and Biocompatibility Acc. Chem. Res. 2013, 46, 792-801 10.1021/ar3000986
7. Zhang, Z.; Wang, J.; Nie, X.; Wen, T.; Ji, Y.; Wu, X.; Zhao, Y.; Chen, C. Near Infrared Laser-Induced Targeted Cancer Therapy Using Thermoresponsive Polymer Encapsulated Gold Nanorods J. Am. Chem. Soc. 2014, 136, 7317-7326 10.1021/ja412735p
8. Dai, Y.; Xiao, H.; Liu, J.; Yuan, Q.; Ma, P. A.; Yang, D.; Li, C.; Cheng, Z.; Hou, Z.; Yang, P. et al. In Vivo Multimodality Imaging and Cancer Therapy by Near-Infrared Light-Triggered Trans-Platinum Pro-Drug-Conjugated Upconverison Nanoparticles J. Am. Chem. Soc. 2013, 135, 18920-18929 10.1021/ja410028q
9. Nair, M.; Guduru, R.; Liang, P.; Hong, J.; Sagar, V.; Khizroev, S. Externally Controlled on-Demand Release of Anti-HIV Drug Using Magneto-Electric Nanoparticles as Carriers Nat. Commun. 2013, 4, 1707 10.1038/ncomms2717
10. Liang, X.; Gao, J.; Jiang, L.; Luo, J.; Jing, L.; Li, X.; Jin, Y.; Dai, Z. Nanohybrid Liposomal Cerasomes with Good Physiological Stability and Rapid Temperature Responsiveness for High Intensity Focused Ultrasound Triggered Local Chemotherapy of Cancer ACS Nano 2015, 9, 1280-1293 10.1021/nn507482w
11. Ling, D.; Park, W.; Park, S.-j.; Lu, Y.; Kim, K. S.; Hackett, M. J.; Kim, B. H.; Yim, H.; Jeon, Y. S.; Na, K. et al. Multifunctional Tumor pH-Sensitive Self-Assembled Nanoparticles for Bimodal Imaging and Treatment of Resistant Heterogeneous Tumors J. Am. Chem. Soc. 2014, 136, 5647-5655 10.1021/ja4108287
12. Stephen, Z. R.; Kievit, F. M.; Veiseh, O.; Chiarelli, P. A.; Fang, C.; Wang, K.; Hatzinger, S. J.; Ellenbogen, R. G.; Silber, J. R.; Zhang, M. Redox-Responsive Magnetic Nanoparticle for Targeted Convection-Enhanced Delivery of O6-Benzylguanine to Brain Tumors ACS Nano 2014, 8, 10383-10395 10.1021/nn503735w
13. Zhang, J.; Yuan, Z. F.; Wang, Y.; Chen, W. H.; Luo, G. F.; Cheng, S. X.; Zhuo, R. X.; Zhang, X. Z. Multifunctional Envelope-Type Mesoporous Silica Nanoparticles for Tumor-Triggered Targeting Drug Delivery J. Am. Chem. Soc. 2013, 135, 5068-5073 10.1021/ja312004m
14. Mo, R.; Jiang, T.; DiSanto, R.; Tai, W.; Gu, Z. ATP-Triggered Anticancer Drug Delivery Nat. Commun. 2014, 5, 3364 10.1038/ncomms4364
15. Di Leva, G.; Garofalo, M.; Croce, C. M. MicroRNAs in Cancer Annu. Rev. Pathol.: Mech. Dis. 2014, 9, 287-314 10.1146/annurev-pathol-012513-104715
16. Bartel, D. P. MicroRNAs: Genomics, Biogenesis, Mechanism, and Function Cell 2004, 116, 281-297 10.1016/S0092-8674(04)00045-5
17. Zhang, P.; Cheng, F.; Zhou, R.; Cao, J.; Li, J.; Burda, C.; Min, Q.; Zhu, J.-J. DNA-Hybrid-Gated Multifunctional Mesoporous Silica Nanocarriers for Dual-Targeted and MicroRNA-Responsive Controlled Drug Delivery Angew. Chem., Int. Ed. 2014, 53, 2371-2375 10.1002/anie.201308920
18. Dong, H.; Lei, J.; Ding, L.; Wen, Y.; Ju, H.; Zhang, X. MicroRNA: Function, Detection, and Bioanalysis Chem. Rev. 2013, 113, 6207-6233 10.1021/cr300362f
19. Zhang, P.; He, Z.; Wang, C.; Chen, J.; Zhao, J.; Zhu, X.; Li, C.-Z.; Min, Q.; Zhu, J.-J. In Situ Amplification of Intracellular MicroRNA with MNAzyme Nanodevices for Multiplexed Imaging, Logic Operation, and Controlled Drug Release ACS Nano 2015, 9, 789-798 10.1021/nn506309d
20. Prusty, D. K.; Kwak, M.; Wildeman, J.; Herrmann, A. Modular Assembly of a Pd Catalyst within a DNA Scaffold for the Amplified Colorimetric and Fluorimetric Detection of Nucleic Acids Angew. Chem., Int. Ed. 2012, 51, 11894-11898 10.1002/anie.201206006
21. Liu, G.; Wan, Y.; Gau, V.; Zhang, J.; Wang, L.; Song, S.; Fan, C. An Enzyme-Based E-DNA Sensor for Sequence-Specific Detection of Femtomolar DNA Targets J. Am. Chem. Soc. 2008, 130, 6820-6825 10.1021/ja800554t
22. Liu, S.; Wang, C.; Zhang, C.; Wang, Y.; Tang, B. Label-Free and Ultrasensitive Electrochemical Detection of Nucleic Acids Based on Autocatalytic and Exonuclease III-Assisted Target Recycling Strategy Anal. Chem. 2013, 85, 2282-2288 10.1021/ac303225p
23. Freeman, R.; Liu, X.; Willner, I. Amplified Multiplexed Analysis of DNA by the Exonuclease III-Catalyzed Regeneration of the Target DNA in the Presence of Functionalized Semiconductor Quantum Dots Nano Lett. 2011, 11, 4456-4461 10.1021/nl202761g
24. Wang, F.; Liu, X.; Willner, I. DNA Switches: From Principles to Applications Angew. Chem., Int. Ed. 2015, 54, 1098-1129 10.1002/anie.201404652
25. Tang, W.; Wang, H.; Wang, D.; Zhao, Y.; Li, N.; Liu, F. DNA Tetraplexes-Based Toehold Activation for Controllable DNA Strand Displacement Reactions J. Am. Chem. Soc. 2013, 135, 13628-13631 10.1021/ja406053b
26. Gottesman, M. M. Mechanisms of Cancer Drug Resistance Annu. Rev. Med. 2002, 53, 615-627 10.1146/annurev.med.53.082901.103929
27. Creixell, M.; Peppas, N. A. Co-Delivery of siRNA and Therapeutic Agents Using Nanocarriers to Overcome Cancer Resistance Nano Today 2012, 7, 367-379 10.1016/j.nantod.2012.06.013
28. Williford, J.-M.; Wu, J.; Ren, Y.; Archang, M. M.; Leong, K. W.; Mao, H.-Q. Recent Advances in Nanoparticle-Mediated siRNA Delivery Annu. Rev. Biomed. Eng. 2014, 16, 347-370 10.1146/annurev-bioeng-071813-105119
29. Kanasty, R.; Dorkin, J. R.; Vegas, A.; Anderson, D. Delivery Materials for siRNA Therapeutics Nat. Mater. 2013, 12, 967-977 10.1038/nmat3765
30. Yang, X.-Z.; Du, J.-Z.; Dou, S.; Mao, C.-Q.; Long, H.-Y.; Wang, J. Sheddable Ternary Nanoparticles for Tumor Acidity-Targeted siRNA Delivery ACS Nano 2012, 6, 771-781 10.1021/nn204240b
31. Hatakeyama, H.; Akita, H.; Ito, E.; Hayashi, Y.; Oishi, M.; Nagasaki, Y.; Danev, R.; Nagayama, K.; Kaji, N.; Kikuchi, H. et al. Systemic Delivery of siRNA to Tumors Using a Lipid Nanoparticle Containing a Tumor-Specific Cleavable PEG-Lipid Biomaterials 2011, 32, 4306-4316 10.1016/j.biomaterials.2011.02.045
32. Perche, F.; Biswas, S.; Wang, T.; Zhu, L.; Torchilin, V. P. Hypoxia-Targeted siRNA Delivery Angew. Chem., Int. Ed. 2014, 53, 3362-3366 10.1002/anie.201308368
33. Zhang, K.; Zhu, X.; Jia, F.; Auyeung, E.; Mirkin, C. A. Temperature-Activated Nucleic Acid Nanostructures J. Am. Chem. Soc. 2013, 135, 14102-14105 10.1021/ja408465t
34. Barhoumi, A.; Wang, W.; Zurakowski, D.; Langer, R. S.; Kohane, D. S. Photothermally Targeted Thermosensitive Polymer-Masked Nanoparticles Nano Lett. 2014, 14, 3697-3701 10.1021/nl403733z
35. Morlieras, J.; Dufort, S.; Sancey, L.; Truillet, C.; Mignot, A.; Rossetti, F.; Dentamaro, M.; Laurent, S.; Vander Elst, L.; Muller, R. N. et al. Functionalization of Small Rigid Platforms with Cyclic RGD Peptides for Targeting Tumors Overexpressing αvβ3-Integrins Bioconjugate Chem. 2013, 24, 1584-1597 10.1021/bc4002097
36. Biswas, S.; Kinbara, K.; Niwa, T.; Taguchi, H.; Ishii, N.; Watanabe, S.; Miyata, K.; Kataoka, K.; Aida, T. Biomolecular Robotics for Chemomechanically Driven Guest Delivery Fuelled by Intracellular ATP Nat. Chem. 2013, 5, 613-620 10.1038/nchem.1681
37. Wang, F.; Lu, C.-H.; Willner, I. From Cascaded Catalytic Nucleic Acids to Enzyme-DNA Nanostructures: Controlling Reactivity, Sensing, Logic Operations, and Assembly of Complex Structures Chem. Rev. 2014, 114, 2881-2941 10.1021/cr400354z
38. Zhou, T.; Chen, P.; Niu, L.; Jin, J.; Liang, D.; Li, Z.; Yang, Z.; Liu, D. pH-Responsive Size-Tunable Self-Assembled DNA Dendrimers Angew. Chem., Int. Ed. 2012, 51, 11271-11274 10.1002/anie.201205862
39. Xiao, Z.; Ji, C.; Shi, J.; Pridgen, E. M.; Frieder, J.; Wu, J.; Farokhzad, O. C. DNA Self-Assembly of Targeted Near-Infrared-Responsive Gold Nanoparticles for Cancer Thermo-Chemotherapy Angew. Chem., Int. Ed. 2012, 51, 11853-11857 10.1002/anie.201204018
40. Sun, T.-M.; Du, J.-Z.; Yao, Y.-D.; Mao, C.-Q.; Dou, S.; Huang, S.-Y.; Zhang, P.-Z.; Leong, K. W.; Song, E.-W.; Wang, J. Simultaneous Delivery of siRNA and Paclitaxel via a "Two-in-One" Micelleplex Promotes Synergistic Tumor Suppression ACS Nano 2011, 5, 1483-1494 10.1021/nn103349h
41. Huschka, R.; Barhoumi, A.; Liu, Q.; Roth, J. A.; Ji, L.; Halas, N. J. Gene Silencing by Gold Nanoshell- Mediated Delivery and Laser-Triggered Release of Antisense Oligonucleotide and siRNA ACS Nano 2012, 6, 7681-7691 10.1021/nn301135w
42. Chou, T.-C. Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method Cancer Res. 2010, 70, 440-446 10.1158/0008-5472.CAN-09-1947
43. Ye, Y.; Chen, X. Integrin Targeting for Tumor Optical Imaging Theranostics 2011, 1, 102-126 10.7150/thno/v01p0102
44. Achilefu, S.; Bloch, S.; Markiewicz, M. A.; Zhong, T.; Ye, Y.; Dorshow, R. B.; Chance, B.; Liang, K. Synergistic Effects of Light-Emitting Probes and Peptides for Targeting and Monitoring Integrin Expression Proc. Natl. Acad. Sci. U. S. A. 2005, 102, 7976-7981 10.1073/pnas.0503500102
45. Hölig, P.; Bach, M.; Völkel, T.; Nahde, T.; Hoffmann, S.; Müller, R.; Kontermann, R. E. Novel RGD Lipopeptides for the Targeting of Liposomes to Integrin-Expressing Endothelial and Melanoma Cells Protein Eng., Des. Sel. 2004, 17, 433-441 10.1093/protein/gzh055
46. Krichevsky, A. M.; Gabriely, G. miR-21: A Small Multi-Faceted RNA J. Cell. Mol. Med. 2009, 13, 39-53 10.1111/j.1582-4934.2008.00556.x
47. Pei, H.; Zuo, X.; Zhu, D.; Huang, Q.; Fan, C. Functional DNA Nanostructures for Theranostic Applications Acc. Chem. Res. 2014, 47, 550-559 10.1021/ar400195t