Linking MedDRA®-Coded Clinical Phenotypes to Biological Mechanisms by the Ontology of Adverse Events: A Pilot Study on Tyrosine Kinase Inhibitors

Drug Safety

Volumn 39, Issue 7, 2016, Pages 697-707

  Sarntivijai, Sirarat ^a,b   Zhang, Shelley ^b   Jagannathan, Desikan G ^b   Zaman, Shadia ^a   Burkhart, Keith K ^a   Omenn, Gilbert S ^b,c,d   He, Yongqun ^b,d   Athey, Brian D ^b,d   Abernethy, Darrell R ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF MICHIGAN SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CETUXIMAB; DASATINIB; IMATINIB; LAPATINIB; MONOCLONAL ANTIBODY; PROTEIN TYROSINE KINASE INHIBITOR; TRASTUZUMAB; PROTEIN KINASE INHIBITOR;

ADVERSE DRUG REACTION; ARTICLE; CARDIOTOXICITY; CONCEPT MAPPING; CONGESTIVE HEART FAILURE; DISEASE CLASSIFICATION; DRUG SAFETY; DRUG SURVEILLANCE PROGRAM; FOOD AND ADMINISTRATION ADVERSE EVENT REPORTING SYSTEM; FOOD AND DRUG ADMINISTRATION; HEART FAILURE; HEART VENTRICLE FUNCTION; HUMAN; MARKUP LANGUAGE; MEDICAL DICTIONARY FOR REGULATORY ACTIVITIES; PILOT STUDY; PLEURA EFFUSION; PRIORITY JOURNAL; UNITED STATES;

ADVERSE DRUG REACTION REPORTING SYSTEMS; ANTIBODIES, MONOCLONAL; HUMANS; PILOT PROJECTS; PROTEIN KINASE INHIBITORS; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 84961839097     PISSN: 01145916     EISSN: 11791942     Source Type: Journal    
DOI: 10.1007/s40264-016-0414-0     Document Type: Article

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