메뉴 건너뛰기




Volumn 6, Issue , 2016, Pages

Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import

Author keywords

[No Author keywords available]

Indexed keywords

CORE PROTEIN; MX1 PROTEIN, HUMAN; MYXOVIRUS RESISTANCE PROTEIN; NP PROTEIN, INFLUENZA A VIRUS; RNA BINDING PROTEIN;

EID: 84961806329     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep23138     Document Type: Article
Times cited : (152)

References (55)
  • 1
    • 84902494505 scopus 로고    scopus 로고
    • Influenza viruses en route from birds to man
    • Klenk, H. D. Influenza viruses en route from birds to man. Cell Host Microbe 15, 653-654 (2014).
    • (2014) Cell Host Microbe , vol.15 , pp. 653-654
    • Klenk, H.D.1
  • 2
    • 84898625116 scopus 로고    scopus 로고
    • Peering into the crystal ball: Influenza pandemics and vaccine efficacy
    • Miller, M. S., Palese, P. Peering into the crystal ball: influenza pandemics and vaccine efficacy. Cell 157, 294-299 (2014).
    • (2014) Cell , vol.157 , pp. 294-299
    • Miller, M.S.1    Palese, P.2
  • 3
    • 0036645752 scopus 로고    scopus 로고
    • The continued pandemic threat posed by avian influenza viruses in Hong Kong
    • Hatta, M., Kawaoka, Y. The continued pandemic threat posed by avian influenza viruses in Hong Kong. Trends Microbiol. 10, 340-344 (2002).
    • (2002) Trends Microbiol. , vol.10 , pp. 340-344
    • Hatta, M.1    Kawaoka, Y.2
  • 5
    • 84939979344 scopus 로고    scopus 로고
    • Transmission of influenza A viruses
    • Neumann, G., Kawaoka, Y. Transmission of influenza A viruses. Virology 479-480, 234-246 (2015).
    • (2015) Virology , vol.479-480 , pp. 234-246
    • Neumann, G.1    Kawaoka, Y.2
  • 6
    • 84880366045 scopus 로고    scopus 로고
    • Adaptation of avian influenza A virus polymerase in mammals to overcome the host species barrier
    • Manz, B., Schwemmle, M., Brunotte, L. Adaptation of avian influenza A virus polymerase in mammals to overcome the host species barrier. J. Virol. 87, 7200-7209 (2013).
    • (2013) J. Virol. , vol.87 , pp. 7200-7209
    • Manz, B.1    Schwemmle, M.2    Brunotte, L.3
  • 8
    • 84898662125 scopus 로고    scopus 로고
    • Identification, characterization, and natural selection of mutations driving airborne transmission of A/H5N1 virus
    • Linster, M. et al. Identification, characterization, and natural selection of mutations driving airborne transmission of A/H5N1 virus. Cell 157, 329-339 (2014).
    • (2014) Cell , vol.157 , pp. 329-339
    • Linster, M.1
  • 9
    • 0030748536 scopus 로고    scopus 로고
    • Avian influenza A viruses differ from human viruses by recognition of sialyloligosaccharides and gangliosides and by a higher conservation of the HA receptor-binding site
    • Matrosovich, M. N. et al. Avian influenza A viruses differ from human viruses by recognition of sialyloligosaccharides and gangliosides and by a higher conservation of the HA receptor-binding site. Virology 233, 224-234 (1997).
    • (1997) Virology , vol.233 , pp. 224-234
    • Matrosovich, M.N.1
  • 10
    • 84862618108 scopus 로고    scopus 로고
    • Airborne transmission of influenza A/H5N1 virus between ferrets
    • Herfst, S. et al. Airborne transmission of influenza A/H5N1 virus between ferrets. Science 336, 1534-1541 (2012).
    • (2012) Science , vol.336 , pp. 1534-1541
    • Herfst, S.1
  • 11
    • 84861394598 scopus 로고    scopus 로고
    • Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets
    • Imai, M. et al. Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets. Nature 486, 420-428 (2012).
    • (2012) Nature , vol.486 , pp. 420-428
    • Imai, M.1
  • 12
    • 0035823083 scopus 로고    scopus 로고
    • Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses
    • Hatta, M., Gao, P., Halfmann, P., Kawaoka, Y. Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses. Science 293, 1840-1842 (2001).
    • (2001) Science , vol.293 , pp. 1840-1842
    • Hatta, M.1    Gao, P.2    Halfmann, P.3    Kawaoka, Y.4
  • 13
    • 78751622104 scopus 로고    scopus 로고
    • Differential use of importin-alpha isoforms governs cell tropism and host adaptation of influenza virus
    • Gabriel, G. et al. Differential use of importin-alpha isoforms governs cell tropism and host adaptation of influenza virus. Nat. Commun. 2, 156 (2011).
    • (2011) Nat. Commun. , vol.2 , pp. 156
    • Gabriel, G.1
  • 14
    • 33744938909 scopus 로고    scopus 로고
    • Properties and dissemination of H5N1 viruses isolated during an influenza outbreak in migratory waterfowl in western China
    • Chen, H. et al. Properties and dissemination of H5N1 viruses isolated during an influenza outbreak in migratory waterfowl in western China. J. Virol. 80, 5976-5983 (2006).
    • (2006) J. Virol. , vol.80 , pp. 5976-5983
    • Chen, H.1
  • 16
    • 84867399426 scopus 로고    scopus 로고
    • A cross-species view on viruses
    • Sawyer, S. L., Elde, N. C. A cross-species view on viruses. Curr. Opin. Virol. 2, 561-568 (2012).
    • (2012) Curr. Opin. Virol. , vol.2 , pp. 561-568
    • Sawyer, S.L.1    Elde, N.C.2
  • 17
    • 84862777209 scopus 로고    scopus 로고
    • IFITM3 restricts the morbidity and mortality associated with influenza
    • Everitt, A. R. et al. IFITM3 restricts the morbidity and mortality associated with influenza. Nature 484, 519-523 (2012).
    • (2012) Nature , vol.484 , pp. 519-523
    • Everitt, A.R.1
  • 18
    • 84866740475 scopus 로고    scopus 로고
    • Evolutionary conflicts between viruses and restriction factors shape immunity
    • Duggal, N. K., Emerman, M. Evolutionary conflicts between viruses and restriction factors shape immunity. Nat. Rev. Immunol. 12, 687-695 (2012).
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 687-695
    • Duggal, N.K.1    Emerman, M.2
  • 19
    • 84882883270 scopus 로고    scopus 로고
    • An evolutionary perspective on the broad antiviral specificity of MxA
    • Mitchell, P. S., Emerman, M., Malik, H. S. An evolutionary perspective on the broad antiviral specificity of MxA. Curr. Opin. Microbiol. 16, 493-499 (2013).
    • (2013) Curr. Opin. Microbiol. , vol.16 , pp. 493-499
    • Mitchell, P.S.1    Emerman, M.2    Malik, H.S.3
  • 20
    • 84871484827 scopus 로고    scopus 로고
    • The broad-spectrum antiviral functions of IFIT and IFITM proteins
    • Diamond, M. S., Farzan, M. The broad-spectrum antiviral functions of IFIT and IFITM proteins. Nat. Rev. Immunol. 13, 46-57 (2013).
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 46-57
    • Diamond, M.S.1    Farzan, M.2
  • 21
    • 84925410974 scopus 로고    scopus 로고
    • Mx GTPases: Dynamin-like antiviral machines of innate immunity
    • Haller, O., Staeheli, P., Schwemmle, M., Kochs, G. Mx GTPases: dynamin-like antiviral machines of innate immunity. Trends Microbiol. 23, 154-163 (2015).
    • (2015) Trends Microbiol. , vol.23 , pp. 154-163
    • Haller, O.1    Staeheli, P.2    Schwemmle, M.3    Kochs, G.4
  • 22
    • 84886953102 scopus 로고    scopus 로고
    • Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection
    • Goujon, C. et al. Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection. Nature 502, 559-562 (2013).
    • (2013) Nature , vol.502 , pp. 559-562
    • Goujon, C.1
  • 23
    • 84886949134 scopus 로고    scopus 로고
    • MX2 is an interferon-induced inhibitor of HIV-1 infection
    • Kane, M. et al. MX2 is an interferon-induced inhibitor of HIV-1 infection. Nature 502, 563-566 (2013).
    • (2013) Nature , vol.502 , pp. 563-566
    • Kane, M.1
  • 24
    • 84908690206 scopus 로고    scopus 로고
    • MxB binds to the HIV-1 core and prevents the uncoating process of HIV-1
    • Fricke, T. et al. MxB binds to the HIV-1 core and prevents the uncoating process of HIV-1. Retrovirology 11, 68 (2014).
    • (2014) Retrovirology , vol.11 , pp. 68
    • Fricke, T.1
  • 25
    • 84904684665 scopus 로고    scopus 로고
    • Host and viral determinants of Mx2 antiretroviral activity
    • Busnadiego, I. et al. Host and viral determinants of Mx2 antiretroviral activity. J. Virol. 88, 7738-7752 (2014).
    • (2014) J. Virol. , vol.88 , pp. 7738-7752
    • Busnadiego, I.1
  • 26
    • 0027296520 scopus 로고
    • No enhanced influenza virus resistance of murine and avian cells expressing cloned duck Mx protein
    • Bazzigher, L., Schwarz, A., Staeheli, P. No enhanced influenza virus resistance of murine and avian cells expressing cloned duck Mx protein. Virology 195, 100-112 (1993).
    • (1993) Virology , vol.195 , pp. 100-112
    • Bazzigher, L.1    Schwarz, A.2    Staeheli, P.3
  • 27
    • 0028937519 scopus 로고
    • The interferon-induced Mx protein of chickens lacks antiviral activity
    • Bernasconi, D., Schultz, U., Staeheli, P. The interferon-induced Mx protein of chickens lacks antiviral activity. J. Interferon Cytokine Res. 15, 47-53 (1995).
    • (1995) J. Interferon Cytokine Res. , vol.15 , pp. 47-53
    • Bernasconi, D.1    Schultz, U.2    Staeheli, P.3
  • 28
    • 84890476408 scopus 로고    scopus 로고
    • Mx proteins: Antiviral gatekeepers that restrain the uninvited
    • Verhelst, J., Hulpiau, P., Saelens, X. Mx proteins: antiviral gatekeepers that restrain the uninvited. Microbiol. Mol. Biol. Rev. 77, 551-566 (2013).
    • (2013) Microbiol. Mol. Biol. Rev. , vol.77 , pp. 551-566
    • Verhelst, J.1    Hulpiau, P.2    Saelens, X.3
  • 29
    • 84887131870 scopus 로고    scopus 로고
    • The human interferon-induced MxA protein inhibits early stages of influenza A virus infection by retaining the incoming viral genome in the cytoplasm
    • Xiao, H., Killip, M. J., Staeheli, P., Randall, R. E., Jackson, D. The human interferon-induced MxA protein inhibits early stages of influenza A virus infection by retaining the incoming viral genome in the cytoplasm. J. Virol. 87, 13053-13058 (2013).
    • (2013) J. Virol. , vol.87 , pp. 13053-13058
    • Xiao, H.1    Killip, M.J.2    Staeheli, P.3    Randall, R.E.4    Jackson, D.5
  • 30
    • 79961202011 scopus 로고    scopus 로고
    • The viral nucleoprotein determines Mx sensitivity of influenza A viruses
    • Zimmermann, P., Manz, B., Haller, O., Schwemmle, M., Kochs, G. The viral nucleoprotein determines Mx sensitivity of influenza A viruses. J. Virol. 85, 8133-8140 (2011).
    • (2011) J. Virol. , vol.85 , pp. 8133-8140
    • Zimmermann, P.1    Manz, B.2    Haller, O.3    Schwemmle, M.4    Kochs, G.5
  • 31
    • 0026729086 scopus 로고
    • Overexpression of the influenza virus polymerase can titrate out inhibition by the murine Mx1 protein
    • Huang, T., Pavlovic, J., Staeheli, P., Krystal, M. Overexpression of the influenza virus polymerase can titrate out inhibition by the murine Mx1 protein. J. Virol. 66, 4154-4160 (1992).
    • (1992) J. Virol. , vol.66 , pp. 4154-4160
    • Huang, T.1    Pavlovic, J.2    Staeheli, P.3    Krystal, M.4
  • 32
    • 41149143074 scopus 로고    scopus 로고
    • Influenza A virus strains differ in sensitivity to the antiviral action of Mx-GTPase
    • Dittmann, J. et al. Influenza A virus strains differ in sensitivity to the antiviral action of Mx-GTPase. J. Virol. 82, 3624-3631 (2008).
    • (2008) J. Virol. , vol.82 , pp. 3624-3631
    • Dittmann, J.1
  • 33
    • 84875985517 scopus 로고    scopus 로고
    • Pandemic influenza A viruses escape from restriction by human MxA through adaptive mutations in the nucleoprotein
    • Manz, B. et al. Pandemic influenza A viruses escape from restriction by human MxA through adaptive mutations in the nucleoprotein. PLoS Pathog. 9, e1003279 (2013).
    • (2013) PLoS Pathog. , vol.9 , pp. e1003279
    • Manz, B.1
  • 34
    • 77954972018 scopus 로고    scopus 로고
    • A polymorphism in the hemagglutinin of the human isolate of a highly pathogenic H5N1 influenza virus determines organ tropism in mice
    • Manz, B., Matrosovich, M., Bovin, N., Schwemmle, M. A polymorphism in the hemagglutinin of the human isolate of a highly pathogenic H5N1 influenza virus determines organ tropism in mice. J. Virol. 84, 8316-8321 (2010).
    • (2010) J. Virol. , vol.84 , pp. 8316-8321
    • Manz, B.1    Matrosovich, M.2    Bovin, N.3    Schwemmle, M.4
  • 35
    • 50549103325 scopus 로고    scopus 로고
    • Positive selection at the receptor-binding site of haemagglutinin H5 in viral sequences derived from human tissues
    • Kongchanagul, A. et al. Positive selection at the receptor-binding site of haemagglutinin H5 in viral sequences derived from human tissues. J. Gen. Virol. 89, 1805-1810 (2008).
    • (2008) J. Gen. Virol. , vol.89 , pp. 1805-1810
    • Kongchanagul, A.1
  • 36
    • 29444438899 scopus 로고    scopus 로고
    • The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host
    • Gabriel, G. et al. The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host. Proc. Natl. Acad. Sci. USA 102, 18590-18595 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 18590-18595
    • Gabriel, G.1
  • 37
    • 4143153932 scopus 로고    scopus 로고
    • Model suggesting that replication of influenza virus is regulated by stabilization of replicative intermediates
    • Vreede, F. T., Jung, T. E., Brownlee, G. G. Model suggesting that replication of influenza virus is regulated by stabilization of replicative intermediates. J. Virol. 78, 9568-9572 (2004).
    • (2004) J. Virol. , vol.78 , pp. 9568-9572
    • Vreede, F.T.1    Jung, T.E.2    Brownlee, G.G.3
  • 38
    • 14544270958 scopus 로고    scopus 로고
    • An unconventional NLS is critical for the nuclear import of the influenza A virus nucleoprotein and ribonucleoprotein
    • Cros, J. F., Garcia-Sastre, A., Palese, P. An unconventional NLS is critical for the nuclear import of the influenza A virus nucleoprotein and ribonucleoprotein. Traffic 6, 205-213 (2005).
    • (2005) Traffic , vol.6 , pp. 205-213
    • Cros, J.F.1    Garcia-Sastre, A.2    Palese, P.3
  • 39
    • 84870250746 scopus 로고    scopus 로고
    • Nuclear import of the influenza A virus transcriptional machinery
    • Hutchinson, E. C., Fodor, E. Nuclear import of the influenza A virus transcriptional machinery. Vaccine 30, 7353-7358 (2012).
    • (2012) Vaccine , vol.30 , pp. 7353-7358
    • Hutchinson, E.C.1    Fodor, E.2
  • 40
    • 0026070664 scopus 로고
    • Transport of incoming influenza virus nucleocapsids into the nucleus
    • Martin, K., Helenius, A. Transport of incoming influenza virus nucleocapsids into the nucleus. J. Virol. 65, 232-244 (1991).
    • (1991) J. Virol. , vol.65 , pp. 232-244
    • Martin, K.1    Helenius, A.2
  • 41
    • 0029130751 scopus 로고
    • Nuclear import of influenza virus RNA can be mediated by viral nucleoprotein and transport factors required for protein import
    • O'Neill, R. E., Jaskunas, R., Blobel, G., Palese, P., Moroianu, J. Nuclear import of influenza virus RNA can be mediated by viral nucleoprotein and transport factors required for protein import. J. Biol. Chem. 270, 22701-22704 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 22701-22704
    • O'Neill, R.E.1    Jaskunas, R.2    Blobel, G.3    Palese, P.4    Moroianu, J.5
  • 42
    • 34250363900 scopus 로고    scopus 로고
    • Nuclear import of influenza A viral ribonucleoprotein complexes is mediated by two nuclear localization sequences on viral nucleoprotein
    • Wu, W. W., Sun, Y. H., Pante, N. Nuclear import of influenza A viral ribonucleoprotein complexes is mediated by two nuclear localization sequences on viral nucleoprotein. Virol. J. 4, 49 (2007).
    • (2007) Virol. J. , vol.4 , pp. 49
    • Wu, W.W.1    Sun, Y.H.2    Pante, N.3
  • 43
    • 68549085409 scopus 로고    scopus 로고
    • Importins and beyond: Non-conventional nuclear transport mechanisms
    • Wagstaff, K. M., Jans, D. A. Importins and beyond: non-conventional nuclear transport mechanisms. Traffic 10, 1188-1198 (2009).
    • (2009) Traffic , vol.10 , pp. 1188-1198
    • Wagstaff, K.M.1    Jans, D.A.2
  • 44
    • 79551629667 scopus 로고    scopus 로고
    • Dual nuclear import mechanisms of sex determining factor SRY: Intracellular Ca2+ as a switch
    • Kaur, G., Jans, D. A. Dual nuclear import mechanisms of sex determining factor SRY: intracellular Ca2+ as a switch. FASEB J. 25, 665-675 (2011).
    • (2011) FASEB J. , vol.25 , pp. 665-675
    • Kaur, G.1    Jans, D.A.2
  • 45
    • 79951975187 scopus 로고    scopus 로고
    • An AlphaScreen(R)-based assay for high-throughput screening for specific inhibitors of nuclear import
    • Wagstaff, K. M., Rawlinson, S. M., Hearps, A. C., Jans, D. A. An AlphaScreen(R)-based assay for high-throughput screening for specific inhibitors of nuclear import. J. Biomol. Screen 16, 192-200 (2011).
    • (2011) J. Biomol. Screen , vol.16 , pp. 192-200
    • Wagstaff, K.M.1    Rawlinson, S.M.2    Hearps, A.C.3    Jans, D.A.4
  • 46
    • 84884542325 scopus 로고    scopus 로고
    • Nuclear localization of dengue virus (DENV) 1-4 non-structural protein 5; Protection against all 4 DENV serotypes by the inhibitor Ivermectin
    • Tay, M. Y. et al. Nuclear localization of dengue virus (DENV) 1-4 non-structural protein 5; protection against all 4 DENV serotypes by the inhibitor Ivermectin. Antiviral Res. 99, 301-306 (2013).
    • (2013) Antiviral Res. , vol.99 , pp. 301-306
    • Tay, M.Y.1
  • 47
    • 84860153620 scopus 로고    scopus 로고
    • Ivermectin is a specific inhibitor of importin alpha/betamediated nuclear import able to inhibit replication of HIV-1 and dengue virus
    • Wagstaff, K. M., Sivakumaran, H., Heaton, S. M., Harrich, D., Jans, D. A. Ivermectin is a specific inhibitor of importin alpha/betamediated nuclear import able to inhibit replication of HIV-1 and dengue virus. Biochem. J. 443, 851-856 (2012).
    • (2012) Biochem. J. , vol.443 , pp. 851-856
    • Wagstaff, K.M.1    Sivakumaran, H.2    Heaton, S.M.3    Harrich, D.4    Jans, D.A.5
  • 48
    • 84905663615 scopus 로고    scopus 로고
    • A nuclear transport inhibitor that modulates the unfolded protein response and provides in vivo protection against lethal dengue virus infection
    • Fraser, J. E. et al. A nuclear transport inhibitor that modulates the unfolded protein response and provides in vivo protection against lethal dengue virus infection. J. Infect. Dis. 210, 1780-1791 (2014).
    • (2014) J. Infect. Dis. , vol.210 , pp. 1780-1791
    • Fraser, J.E.1
  • 49
    • 84864029737 scopus 로고    scopus 로고
    • Nuclear trafficking of proteins from RNA viruses: Potential target for antivirals?
    • Caly, L., Wagstaff, K. M., Jans, D. A. Nuclear trafficking of proteins from RNA viruses: potential target for antivirals? Antiviral Res 95, 202-206 (2012).
    • (2012) Antiviral Res , vol.95 , pp. 202-206
    • Caly, L.1    Wagstaff, K.M.2    Jans, D.A.3
  • 50
    • 84897537106 scopus 로고    scopus 로고
    • Identification of amino acid changes that may have been critical for the genesis of A(H7N9) influenza viruses
    • Neumann, G., Macken, C. A., Kawaoka, Y. Identification of amino acid changes that may have been critical for the genesis of A(H7N9) influenza viruses. J. Virol. 88, 4877-4896 (2014).
    • (2014) J. Virol. , vol.88 , pp. 4877-4896
    • Neumann, G.1    MacKen, C.A.2    Kawaoka, Y.3
  • 51
    • 84921658489 scopus 로고    scopus 로고
    • The nucleoprotein of newly emerged H7N9 influenza A virus harbors a unique motif conferring resistance to antiviral human MxA
    • Riegger, D. et al. The nucleoprotein of newly emerged H7N9 influenza A virus harbors a unique motif conferring resistance to antiviral human MxA. J. Virol. 89, 2241-2252 (2015).
    • (2015) J. Virol. , vol.89 , pp. 2241-2252
    • Riegger, D.1
  • 52
    • 84904791696 scopus 로고    scopus 로고
    • An infectious bat-derived chimeric influenza virus harbouring the entry machinery of an influenza A virus
    • Juozapaitis, M. et al. An infectious bat-derived chimeric influenza virus harbouring the entry machinery of an influenza A virus. Nat. Commun. 5, 4448 (2014).
    • (2014) Nat. Commun. , vol.5 , pp. 4448
    • Juozapaitis, M.1
  • 53
  • 54
    • 84871007119 scopus 로고    scopus 로고
    • Adaptive mutations in NEP compensate for defective H5N1 RNA replication in cultured human cells
    • Manz, B., Brunotte, L., Reuther, P., Schwemmle, M. Adaptive mutations in NEP compensate for defective H5N1 RNA replication in cultured human cells. Nat. Commun. 3, 802 (2012).
    • (2012) Nat. Commun. , vol.3 , pp. 802
    • Manz, B.1    Brunotte, L.2    Reuther, P.3    Schwemmle, M.4
  • 55
    • 84880076973 scopus 로고    scopus 로고
    • High-content analysis of sequential events during the early phase of influenza A virus infection
    • Banerjee, I., Yamauchi, Y., Helenius, A., Horvath, P. High-content analysis of sequential events during the early phase of influenza A virus infection. PLoS One 8, e68450 (2013).
    • (2013) PLoS One , vol.8 , pp. e68450
    • Banerjee, I.1    Yamauchi, Y.2    Helenius, A.3    Horvath, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.