High-Content Analysis of Sequential Events during the Early Phase of Influenza A Virus Infection

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Banerjee, Indranil ^a,b   Yamauchi, Yohei ^a   Helenius, Ari ^a   Horvath, Peter ^a  

^a ETH ZURICH   (Switzerland)

^b FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BINDING ASSAY; CONFORMATIONAL TRANSITION; CONTENT ANALYSIS; CONTROLLED STUDY; DISEASE COURSE; EARLY INFECTION; ENDOCYTOSIS; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IMAGE PROCESSING; INFLUENZA A; INFLUENZA VIRUS A H3N2; MEMBRANE BINDING; MEMBRANE FUSION; NONHUMAN; PROTEIN SYNTHESIS; VIRUS ATTACHMENT; VIRUS DETECTION; VIRUS ENTRY; VIRUS ENVELOPE; VIRUS PARTICLE; VIRUS STRAIN; VIRUS TRANSCRIPTION;

ACIDS; ACTIVE TRANSPORT, CELL NUCLEUS; CAPSID; CELL LINE, TUMOR; CELL MEMBRANE; CELL NUCLEUS; ENDOCYTOSIS; HOST-PATHOGEN INTERACTIONS; HUMANS; IMAGING, THREE-DIMENSIONAL; INFLUENZA A VIRUS; INFLUENZA, HUMAN; MEMBRANE FUSION; NUCLEOPROTEINS; PROTEIN BIOSYNTHESIS; STATISTICS AS TOPIC; TIME FACTORS; VIRUS INTERNALIZATION;

EID: 84880076973     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0068450     Document Type: Article

References (22)

1. Matlin KS, Reggio H, Helenius A, Simons K, (1981) Infectious entry pathway of influenza virus in a canine kidney cell line. J Cell Biol 91: 601-613.
2. de Vries E, Tscherne DM, Wienholts MJ, Cobos-Jimenez V, Scholte F, et al. (2011) Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an alternative entry pathway. PLoS Pathog 7: e1001329.
3. White J, Kartenbeck J, Helenius A, (1982) Membrane fusion activity of influenza virus. EMBO J 1: 217-222.
4. Lakadamyali M, Rust MJ, Zhuang X, (2004) Endocytosis of influenza viruses. Microbes Infect 6: 929-936.
5. Stertz S, Shaw ML, (2011) Uncovering the global host cell requirements for influenza virus replication via RNAi screening. Microbes Infect 13: 516-525.
6. Doms RW, Helenius A, White J, (1985) Membrane fusion activity of the influenza virus hemagglutinin. The low pH-induced conformational change. J Biol Chem 260: 2973-2981.
7. Daniels PS, Jeffries S, Yates P, Schild GC, Rogers GN, et al. (1987) The receptor-binding and membrane-fusion properties of influenza virus variants selected using anti-haemagglutinin monoclonal antibodies. EMBO J 6: 1459-1465.
8. Yamauchi Y, Boukari H, Banerjee I, Sbalzarini IF, Horvath P, et al. (2011) Histone deacetylase 8 is required for centrosome cohesion and influenza A virus entry. PLoS Pathog 7: e1002316.
9. Webster RG, Brown LE, Jackson DC, (1983) Changes in the antigenicity of the hemagglutinin molecule of H3 influenza virus at acidic pH. Virology 126: 587-599.
10. Sakai T, Ohuchi M, Imai M, Mizuno T, Kawasaki K, et al. (2006) Dual wavelength imaging allows analysis of membrane fusion of influenza virus inside cells. J Virol 80: 2013-2018.
11. Martin K, Helenius A, (1991) Transport of incoming influenza virus nucleocapsids into the nucleus. J Virol 65: 232-244.
12. Horvath P, Wild T, Kutay U, Csucs G, (2011) Machine Learning Improves the Precision and Robustness of High-Content Screens: Using Nonlinear Multiparametric Methods to Analyze Screening Results. J Biomol Screen 16: 1059-1067.
13. Jones TR, Kang IH, Wheeler DB, Lindquist RA, Papallo A, et al. (2008) CellProfiler Analyst: data exploration and analysis software for complex image-based screens. BMC Bioinformatics 9: 482.
14. Zhang JH, Chung TD, Oldenburg KR, (1999) A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays. J Biomol Screen 4: 1087-0571.
15. Olivo-Marin J-C, (2002) Extraction of spots in biological images using multiscale products. Pattern Recognition 35: 1989-1996.
16. Carpenter AE, Jones TR, Lamprecht MR, Clarke C, Kang IH, et al. (2006) CellProfiler: image analysis software for identifying and quantifying cell phenotypes. Genome Biol 7: R100.
17. Witten I, Frank E (2005) Data Mining: Practical Machine Learning Tools and Techniques: Morgan Kaufmann.
18. Brass AL, Huang IC, Benita Y, John SP, Krishnan MN, et al. (2009) The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus. Cell 139: 1243-1254.
19. Karlas A, Machuy N, Shin Y, Pleissner KP, Artarini A, et al. (2010) Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication. Nature 463: 818-822.
20. Hao L, Sakurai A, Watanabe T, Sorensen E, Nidom CA, et al. (2008) Drosophila RNAi screen identifies host genes important for influenza virus replication. Nature 454: 890-893.
21. Huotari J, Meyer-Schaller N, Hubner M, Stauffer S, Katheder N, et al. (2012) Cullin-3 regulates late endosome maturation. Proc Natl Acad Sci U S A 109: 823-828.
22. Fawcett T, (2006) An introduction to ROC analysis. Pattern Recogn Lett 27: 861-874.