Microbiota manipulation for weight change

Microbial Pathogenesis

Volumn 106, Issue , 2017, Pages 146-161

  Dror, Tal ^a   Dickstein, Yaakov ^b   Dubourg, Grégory ^c,d   Paul, Mical ^a,b  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b Infectious Diseases Unit   (Israel)

^c TIMONE HOSPITAL   (France)

^d INSERM   (France)

Author keywords

Antibiotics; Meta analysis; Prebiotics; Probiotics; Synbiotics; Systematic review; Weight

Indexed keywords

ANTIBIOTIC AGENT; AZITHROMYCIN; FRUCTOSE OLIGOSACCHARIDE; PLACEBO; PREBIOTIC AGENT; PROBIOTIC AGENT; SYNBIOTIC AGENT; ANTIINFECTIVE AGENT;

AGE DISTRIBUTION; ANTIBIOTIC THERAPY; BODY MASS; BODY WEIGHT MANAGEMENT; BRONCHIECTASIS; CYSTIC FIBROSIS; DIET SUPPLEMENTATION; HUMAN; INTESTINE FLORA; LACTOBACILLUS; LUNG DISEASE; META ANALYSIS; MICROBIAL COMMUNITY; NONHUMAN; OUTCOME ASSESSMENT; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SYSTEMATIC REVIEW; TREATMENT DURATION; TREATMENT OUTCOME; WEIGHT CHANGE; WEIGHT GAIN; ADOLESCENT; ADULT; CHILD; DRUG EFFECTS; INFANT; LUNG DISEASES; META ANALYSIS (TOPIC); MICROBIOLOGY; OBESITY; PLACEBO EFFECT; PRESCHOOL CHILD; WEIGHT REDUCTION;

ADOLESCENT; ADULT; ANTI-BACTERIAL AGENTS; AZITHROMYCIN; BRONCHIECTASIS; CHILD; CHILD, PRESCHOOL; GASTROINTESTINAL MICROBIOME; HUMANS; INFANT; LACTOBACILLUS; LUNG DISEASES; META-ANALYSIS AS TOPIC; OBESITY; PLACEBO EFFECT; PREBIOTICS; PROBIOTICS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SYNBIOTICS; WEIGHT GAIN; WEIGHT LOSS;

EID: 84961771375     PISSN: 08824010     EISSN: 10961208     Source Type: Journal    
DOI: 10.1016/j.micpath.2016.01.002     Document Type: Review

References (111)

1. [1] Fanaro, S., Jelinek, J., Stahl, B., Boehm, G., Kock, R., Vigi, V., Acidic oligosaccharides from pectin hydrolysate as new component for infant formulae: effect on intestinal flora, stool characteristics, and pH. J. Pediatr. Gastroenterol. Nutr. 41:2 (2005), 186–190.
2. [2] Wood AJJ, M.D., Yanovski, S.Z., Yanovski, Jack A., Obesity. N. Engl. J. Med. 346:8 (2002), 591–660.
3. [3] Speliotes, E.K., Willer, C.J., Berndt, S.I., Monda, K.L., Thorleifsson, G., Jackson, A.U., et al. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat. Genet. 42:11 (2010), 937–948.
4. [4] Xia, Q., Grant, S.F., The genetics of human obesity. Ann. N. Y. Acad. Sci. 1281 (2013), 178–190.
5. [5] Tuomi, T., Santoro, N., Caprio, S., Cai, M., Weng, J., Groop, L., The many faces of diabetes: a disease with increasing heterogeneity. Lancet 383:9922 (2014), 1084–1094.
6. [6] Frayling, T.M., Timpson, N.J., Weedon, M.N., Zeggini, E., Freathy, R.M., Lindgren, C.M., et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 316:5826 (2007), 889–894.
7. [7] Loos, R.J., Lindgren, C.M., Li, S., Wheeler, E., Zhao, J.H., Prokopenko, I., et al. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat. Genet. 40:6 (2008), 768–775.
8. [8] Thorleifsson, G., Walters, G.B., Gudbjartsson, D.F., Steinthorsdottir, V., Sulem, P., Helgadottir, A., et al. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat. Genet. 41:1 (2009), 18–24.
9. [9] Cecil, J.E., Tavendale, R., Watt, P., Hetherington, M.M., Palmer, C.N., An obesity-associated FTO gene variant and increased energy intake in children. N. Engl. J. Med. 359:24 (2008), 2558–2566.
10. [10] Larson, N.I., Wall, M.M., Story, M.T., Neumark-Sztainer, D.R., Home/family, peer, school, and neighborhood correlates of obesity in adolescents. Obes. (Silver Spring) 21:9 (2013), 1858–1869.
11. [11] Ussar, S., Griffin, N.W., Bezy, O., Fujisaka, S., Vienberg, S., Softic, S., et al. Interactions between gut microbiota, host genetics and diet modulate the predisposition to obesity and metabolic syndrome. Cell Metab. 22:3 (2015), 516–530.
12. [12] Tagliabue, A., Elli, M., The role of gut microbiota in human obesity: recent findings and future perspectives. Nutr. Metab. Cardiovasc Dis. 23:3 (2013), 160–168.
13. [13] Tehrani, A.B., Nezami, B.G., Gewirtz, A., Srinivasan, S., Obesity and its associated disease: a role for microbiota?. Neurogastroenterol. Motil. 24:4 (2012), 305–311.
14. [14] Backhed, F., Ding, H., Wang, H., Hooper, L.V., Koh, G.Y., Nagy, A., et al. The gut microbiota as an environemental factor that regulates fat storage. Proc. Natl. Acad. Sci. U. S. A. 101:44 (2004), 15718–15723.
15. [15] Ley, R.E., Turnbaugh, P.J., Klein, S., Gordon, J.I., Microbial ecology: human gut microbes associated with obesity. Nature 444:7122 (2006), 1022–1023.
16. [16] Jumpertz, R., Le, D.S., Turnbaugh, P.J., Trinidad, C., Bogardus, C., Gordon, J.I., et al. Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans. Am. J. Clin. Nutr. 94:1 (2011), 58–65.
17. [17] Turnbaugh, P.J., Ley, R.E., Mahowald, M.A., Magrini, V., Mardis, E.R., Gordon, J.I., An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 444:7122 (2006), 1027–1031.
18. [18] Turnbaugh, P.J., Hamady, M., Yatsunenko, T., Cantarel, B.L., Duncan, A., Ley, R.E., et al. A core gut microbiome in obese and lean twins. Nature 457:7228 (2009), 480–484.
19. [19] Macfarlane, S., Macfarlane, G.T., Cummings, J.H., Review article: prebiotics in the gastrointestinal tract. Aliment. Pharmacol. Ther. 24:5 (2006), 701–714.
20. [20] Thomas, L.V., Ockhuizen, T., Suzuki, K., Exploring the influence of the gut microbiota and probiotics on health: a symposium report. Br. J. Nutr. 112:Suppl. 1 (2014), S1–S18.
21. [21] Le Barz, M., Anhe, F.F., Varin, T.V., Desjardins, Y., Levy, E., Roy, D., et al. Probiotics as complementary treatment for metabolic disorders. Diabetes Metab. J. 39:4 (2015), 291–303.
22. [22] Hur, K.Y., Lee, M.S., Gut microbiota and metabolic disorders. Diabetes Metab. J. 39:3 (2015), 198–203.
23. [23] Yoo, S.R., Kim, Y.J., Park, D.Y., Jung, U.J., Jeon, S.M., Ahn, Y.T., et al. Probiotics L. plantarum and L. curvatus in combination alter hepatic lipid metabolism and suppress diet-induced obesity. Obes. (Silver Spring) 21:12 (2013), 2571–2578.
24. [24] Yadav, H., Lee, J.H., Lloyd, J., Walter, P., Rane, S.G., Beneficial metabolic effects of a probiotic via butyrate-induced GLP-1 hormone secretion. J. Biol. Chem. 288:35 (2013), 25088–25097.
25. [25] Bindels, L.B., Neyrinck, A.M., Salazar, N., Taminiau, B., Druart, C., Muccioli, G.G., et al. Non digestible oligosaccharides modulate the gut microbiota to control the development of leukemia and associated cachexia in mice. PLoS One, 10(6), 2015, e0131009.
26. [26] Kerac, M., Bunn, J., Seal, A., Thindwa, M., Tomkins, A., Sadler, K., et al. Probiotics and prebiotics for severe acute malnutrition (PRONUT study): a double-blind efficacy randomised controlled trial in Malawi. Lancet 374:9684 (2009), 136–144.
27. [27] Underwood, M.A., Salzman, N.H., Bennett, S.H., Barman, M., Mills, D.A., Marcobal, A., et al. A randomized placebo-controlled comparison of 2 prebiotic/probiotic combinations in preterm infants: impact on weight gain, intestinal microbiota, and fecal short-chain fatty acids. J. Pediatr. Gastroenterol. Nutr. 48:2 (2009), 216–225.
28. [28] Silva, M.R., Dias, G., Ferreira, C.L., Franceschini, S.C., Costa, N.M., Growth of preschool children was improved when fed an iron-fortified fermented milk beverage supplemented with Lactobacillus acidophilus. Nutr. Res. 28:4 (2008), 226–232.
29. [29] Firmansyah, A., Dwipoerwantoro, P.G., Kadim, M., Alatas, S., Conus, N., Lestarina, L., et al. Improved growth of toddlers fed a milk containing synbiotics. Asia Pac J. Clin. Nutr. 20:1 (2011), 69–76.
30. [30] Hays, S., Jacquot, A., Gauthier, H., Kempf, C., Beissel, A., Pidoux, O., Probiotics and growth in preterm infants: a randomized controlled trial. PREMAPRO Study Clin. Nutr., 2015 Jul 16, 10.1016/j.clnu.2015.06.006 pii:S0261-5614(15)00180-6. (Epub ahead of print).
31. [31] Liber, A., Szajewska, H., Effect of oligofructose supplementation on body weight in overweight and obese children: a randomised, double-blind, placebo-controlled trial. Br. J. Nutr. 112:12 (2014), 2068–2074.
32. [32] Panigrahi, P., Parida, S., Pradhan, L., Mohapatra, S.S., Misra, P.R., Johnson, J.A., et al. Long-term colonization of a Lactobacillus plantarum synbiotic preparation in the neonatal gut. J. Pediatr. Gastroenterol. Nutr. 47:1 (2008), 45–53.
33. [33] Keeney, K.M., Yurist-Doutsch, S., Arrieta, M.C., Finlay, B.B., Effects of antibiotics on human microbiota and subsequent disease. Annu. Rev. Microbiol. 68 (2014), 217–235.
34. [34] Stiksrud, B., Nowak, P., Nwosu, F.C., Kvale, D., Thalme, A., Sonnerborg, A., et al. Reduced levels of D-dimer and changes in Gut Microbiota composition after probiotic intervention in HIV-Infected individuals on stable ART. J. Acquir Immune Defic. Syndr. 70:4 (2015), 329–337.
35. [35] d'Ettorre, G., Ceccarelli, G., Giustini, N., Serafino, S., Calantone, N., De Girolamo, G., et al. Probiotics reduce inflammation in antiretroviral treated, HIV-infected individuals: results of the “Probio-HIV” clinical trial. PLoS One, 10(9), 2015, e0137200.
36. [36] Maldonado-Lobon, J.A., Gil-Campos, M., Maldonado, J., Lopez-Huertas, E., Flores-Rojas, K., Valero, A.D., et al. Long-term safety of early consumption of Lactobacillus fermentum CECT5716: a 3-year follow-up of a randomized controlled trial. Pharmacol. Res. 95–96 (2015), 12–19.
37. [37] Inostroza, J., Haschke, F., Steenhout, P., Grathwohl, D., Nelson, S.E., Ziegler, E.E., Low-protein formula slows weight gain in infants of overweight mothers. J. Pediatr. Gastroenterol. Nutr. 59:1 (2014), 70–77.
38. [38] Agerholm-Larsen, L., Raben, A., Haulrik, N., Hansen, A.S., Manders, M., Astrup, A., Effect of 8 week intake of probiotic milk products on risk factors for cardiovascular diseases. Eur. J. Clin. Nutr. 54:4 (2000), 288–297.
39. [39] Chang, B.J., Park, S.U., Jang, Y.S., Ko, S.H., Joo, N.M., Kim, S.I., et al. Effect of functional yogurt NY-YP901 in improving the trait of metabolic syndrome. Eur. J. Clin. Nutr. 65:11 (2011), 1250–1255.
40. [40] Doria, E., Buonocore, D., Michelotti, A., Nobile, V., Marzatico, F., Evaluation of a phyto-supplement efficacy as adjuvant in reducing body weight and fat mass in overweight women. Curr. Top. Nutraceutical Res., 11(1/2), 2013, 21.
41. [41] Fathi, Y., Faghih, S., Zibaeenezhad, M.J., Tabatabaei, S.H., Kefir drink leads to a similar weight loss, compared with milk, in a dairy-rich non-energy-restricted diet in overweight or obese premenopausal women: a randomized controlled trial. Eur. J. Nutr., 2015 Feb 5 (Epub ahead of print).
42. [42] Hariri, M., Salehi, R., Feizi, A., Mirlohi, M., Kamali, S., Ghiasvand, R., The effect of probiotic soy milk and soy milk on anthropometric measures and blood pressure in patients with type II diabetes mellitus: a randomized double-blind clinical trial. ARYA Atheroscler. 11:Suppl. 1 (2015), 74–80.
43. [43] Hulston, C.J., Churnside, A.A., Venables, M.C., Probiotic supplementation prevents high-fat, overfeeding-induced insulin resistance in human subjects. Br. J. Nutr. 113:4 (2015), 596–602.
44. [44] Jung, S.P., Lee, K.M., Kang, J.H., Yun, S.I., Park, H.O., Moon, Y., et al. Effect of Lactobacillus gasseri BNR17 on overweight and obese adults: a randomized, double-blind clinical trial. Korean J. Fam. Med. 34:2 (2013), 80–89.
45. [45] Kadooka, Y., Sato, M., Ogawa, A., Miyoshi, M., Uenishi, H., Ogawa, H., et al. Effect of Lactobacillus gasseri SBT2055 in fermented milk on abdominal adiposity in adults in a randomised controlled trial. Br. J. Nutr. 110:9 (2013), 1696–1703.
46. [46] Kadooka, Y., Sato, M., Imaizumi, K., Ogawa, A., Ikuyama, K., Akai, Y., et al. Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial. Eur. J. Clin. Nutr. 64:6 (2010), 636–643.
47. [47] Lee, S.J., Bose, S., Seo, J.G., Chung, W.S., Lim, C.Y., Kim, H., The effects of co-administration of probiotics with herbal medicine on obesity, metabolic endotoxemia and dysbiosis: a randomized double-blind controlled clinical trial. Clin. Nutr. 33:6 (2014), 973–981.
48. [48] Lane, J.A., Murray, L.J., Harvey, I.M., Donovan, J.L., Nair, P., Harvey, R.F., Randomised clinical trial: Helicobacter pylori eradication is associated with a significantly increased body mass index in a placebo-controlled study. Aliment. Pharmacol. Ther. 33:8 (2011), 922–929.
49. [49] Sharafedtinov, K.K., Plotnikova, O.A., Alexeeva, R.I., Sentsova, T.B., Songisepp, E., Stsepetova, J., et al. Hypocaloric diet supplemented with probiotic cheese improves body mass index and blood pressure indices of obese hypertensive patients–a randomized double-blind placebo-controlled pilot study. Nutr. J., 12, 2013, 138.
50. [50] Clement, A., Tamalet, A., Leroux, E., Ravilly, S., Fauroux, B., Jais, J.P., Long term effects of azithromycin in patients with cystic fibrosis: a double blind, placebo controlled trial. Thorax 61:10 (2006), 895–902.
51. [51] Surono, I.S., Koestomo, F.P., Novitasari, N., Zakaria, F.R., Yulianasari, Koesnandar, Novel probiotic Enterococcus faecium IS-27526 supplementation increased total salivary sIgA level and bodyweight of pre-school children: a pilot study. Anaerobe 17:6 (2011), 496–500.
52. [52] Alisi, A., Bedogni, G., Baviera, G., Giorgio, V., Porro, E., Paris, C., et al. Randomised clinical trial: the beneficial effects of VSL#3 in obese children with non-alcoholic steatohepatitis. Aliment. Pharmacol. Ther. 39:11 (2014), 1276–1285.
53. [53] Saiman, L., Anstead, M., Mayer-Hamblett, N., Lands, L.C., Kloster, M., Hocevar-Trnka, J., et al. Effect of azithromycin on pulmonary function in patients with cystic fibrosis uninfected with Pseudomonas aeruginosa: a randomized controlled trial. JAMA 303:17 (2010), 1707–1715.
54. [54] Saiman, L., Marshall, B.C., Mayer-Hamblett, N., Burns, J.L., Quittner, A.L., Cibene, D.A., et al. Azithromycin in patients with cystic fibrosis chronically infected with Pseudomonas aeruginosa: a randomized controlled trial. JAMA 290:13 (2003), 1749–1756.
55. [55] Valery, P.C., Morris, P.S., Byrnes, C.A., Grimwood, K., Torzillo, P.J., Bauert, P.A., et al. Long-term azithromycin for indigenous children with non-cystic-fibrosis bronchiectasis or chronic suppurative lung disease (Bronchiectasis Intervention Study): a multicentre, double-blind, randomised controlled trial. Lancet Respir. Med. 1:8 (2013), 610–620.
56. [56] Abrams, S.A., Griffin, I.J., Hawthorne, K.M., Ellis, K.J., Effect of prebiotic supplementation and calcium intake on body mass index. J. Pediatr. 151:3 (2007), 293–298.
57. [57] Safavi, M., Farajian, S., Kelishadi, R., Mirlohi, M., Hashemipour, M., The effects of synbiotic supplementation on some cardio-metabolic risk factors in overweight and obese children: a randomized triple-masked controlled trial. Int. J. Food Sci. Nutr. 64:6 (2013), 687–693.
58. [58] Gibson, R.A., Barclay, D., Marshall, H., Moulin, J., Maire, J.C., Makrides, M., Safety of supplementing infant formula with long-chain polyunsaturated fatty acids and Bifidobacterium lactis in term infants: a randomised controlled trial. Br. J. Nutr. 101:11 (2009), 1706–1713.
59. [59] Hol, J., van Leer, E.H., Elink Schuurman, B.E., de Ruiter, L.F., Samsom, J.N., Hop, W., et al. The acquisition of tolerance toward cow's milk through probiotic supplementation: a randomized, controlled trial. J. Allergy Clin. Immunol. 121:6 (2008), 1448–1454.
60. [60] Dupont, C., Hol, J., Nieuwenhuis, E.E., Cow's milk allergy modified by E, lactobacilli study g. An extensively hydrolysed casein-based formula for infants with cows' milk protein allergy: tolerance/hypo-allergenicity and growth catch-up. Br. J. Nutr. 113:7 (2015), 1102–1112.
61. [61] Nopchinda, S., Varavithya, W., Phuapradit, P., Sangchai, R., Suthutvoravut, U., Chantraruksa, V., et al. Effect of bifidobacterium Bb12 with or without Streptococcus thermophilus supplemented formula on nutritional status. J. Med. Assoc. Thai 85:Suppl. 4 (2002), S1225–S1231.
62. [62] Puccio, G., Cajozzo, C., Meli, F., Rochat, F., Grathwohl, D., Steenhout, P., Clinical evaluation of a new starter formula for infants containing live Bifidobacterium longum BL999 and prebiotics. Nutrition 23:1 (2007), 1–8.
63. [63] Savino, F., Cordisco, L., Tarasco, V., Palumeri, E., Calabrese, R., Oggero, R., et al. Lactobacillus reuteri DSM 17938 in infantile colic: a randomized, double-blind, placebo-controlled trial. Pediatrics, 126(3), 2010 e526–33.
64. [64] Vajro, P., Mandato, C., Licenziati, M.R., Franzese, A., Vitale, D.F., Lenta, S., et al. Effects of Lactobacillus rhamnosus strain GG in pediatric obesity-related liver disease. J. Pediatr. Gastroenterol. Nutr. 52:6 (2011), 740–743.
65. [65] Vendt, N., Grunberg, H., Tuure, T., Malminiemi, O., Wuolijoki, E., Tillmann, V., et al. Growth during the first 6 months of life in infants using formula enriched with Lactobacillus rhamnosus GG: double-blind, randomized trial. J. Hum. Nutr. Diet. 19:1 (2006), 51–58.
66. [66] Vlieger, A.M., Robroch, A., van Buuren, S., Kiers, J., Rijkers, G., Benninga, M.A., et al. Tolerance and safety of Lactobacillus paracasei ssp. paracasei in combination with Bifidobacterium animalis ssp. lactis in a prebiotic-containing infant formula: a randomised controlled trial. Br. J. Nutr. 102:6 (2009), 869–875.
67. [67] Chorell, E., Karlsson Videhult, F., Hernell, O., Antti, H., West, C.E., Impact of probiotic feeding during weaning on the serum lipid profile and plasma metabolome in infants. Br. J. Nutr. 110:1 (2013), 116–126.
68. [68] West, C.E., Gothefors, L., Granstrom, M., Kayhty, H., Hammarstrom, M.L., Hernell, O., Effects of feeding probiotics during weaning on infections and antibody responses to diphtheria, tetanus and Hib vaccines. Pediatr. Allergy Immunol. 19:1 (2008), 53–60.
69. [69] Urban, M.F., Bolton, K.D., Mokhachane, M., Mphahlele, R.M., Bomela, H.N., Monahang, L., et al. Growth of infants born to HIV-infected women when fed a biologically acidified starter formula with and without probiotics. S Afr. J. Clin. Nutr. 21:1 (2008), 28–32.
70. [70] Cooper, P.A.B.K.D., Mokhachane, M., Velaphi, S.C., Mphahlele, R.M., Bomela, H.N., Monaheng, L., Roux, P., Haschke-Becher, E., Growth of infants born to HIV-positive mothers fed a whey-adapted acidifed starter formula with prebiotics and nucleotides. S. Afr. J. Clin. Nutr. 23:2 (2010), 90–95.
71. [71] Piemontese, P., Gianni, M.L., Braegger, C.P., Chirico, G., Gruber, C., Riedler, J., et al. Tolerance and safety evaluation in a large cohort of healthy infants fed an innovative prebiotic formula: a randomized controlled trial. PLoS One, 6(11), 2011, e28010.
72. [72] Schmelzle, H., Wirth, S., Skopnik, H., Radke, M., Knol, J., Bockler, H.M., et al. Randomized double-blind study of the nutritional efficacy and bifidogenicity of a new infant formula containing partially hydrolyzed protein, a high beta-palmitic acid level, and nondigestible oligosaccharides. J. Pediatr. Gastroenterol. Nutr. 36:3 (2003), 343–351.
73. [73] Ziegler, E., Vanderhoof, J.A., Petschow, B., Mitmesser, S.H., Stolz, S.I., Harris, C.L., et al. Term infants fed formula supplemented with selected blends of prebiotics grow normally and have soft stools similar to those reported for breast-fed infants. J. Pediatr. Gastroenterol. Nutr. 44:3 (2007), 359–364.
74. [74] Ahanchian, H., Nouri, Z., Jafari, S.A., Moghiman, T., Amirian, M.H., Ezzati, A., et al. Synbiotics in children with Cow's milk allergy: a randomized controlled trial. Iran. J. Pediatr. 24:1 (2014), 29–34.
75. [75] Roze, J.C., Barbarot, S., Butel, M.J., Kapel, N., Waligora-Dupriet, A.J., De Montgolfier, I., et al. An alpha-lactalbumin-enriched and symbiotic-supplemented v. a standard infant formula: a multicentre, double-blind, randomised trial. Br. J. Nutr. 107:11 (2012), 1616–1622.
76. [76] Sazawal, S., Dhingra, U., Hiremath, G., Sarkar, A., Dhingra, P., Dutta, A., et al. Effects of Bifidobacterium lactis HN019 and prebiotic oligosaccharide added to milk on iron status, anemia, and growth among children 1 to 4 years old. J. Pediatr. Gastroenterol. Nutr. 51:3 (2010), 341–346.
77. [77] Dupont, C., Rivero, M., Grillon, C., Belaroussi, N., Kalindjian, A., Marin, V., Alpha-lactalbumin-enriched and probiotic-supplemented infant formula in infants with colic: growth and gastrointestinal tolerance. Eur. J. Clin. Nutr. 64:7 (2010), 765–767.
78. [78] Dewulf, E.M., Cani, P.D., Claus, S.P., Fuentes, S., Puylaert, P.G., Neyrinck, A.M., et al. Insight into the prebiotic concept: lessons from an exploratory, double blind intervention study with inulin-type fructans in obese women. Gut 62:8 (2013), 1112–1121.
79. [79] Zarrati, M., Salehi, E., Nourijelyani, K., Mofid, V., Zadeh, M.J., Najafi, F., et al. Effects of probiotic yogurt on fat distribution and gene expression of proinflammatory factors in peripheral blood mononuclear cells in overweight and obese people with or without weight-loss diet. J. Am. Coll. Nutr. 33:6 (2014), 417–425.
80. [80] Savard, P., Lamarche, B., Paradis, M.E., Thiboutot, H., Laurin, E., Roy, D., Impact of Bifidobacterium animalis subsp. lactis BB-12 and, Lactobacillus acidophilus LA-5-containing yoghurt, on fecal bacterial counts of healthy adults. Int. J. Food Microbiol. 149:1 (2011), 50–57.
81. [81] Woodard, G.A., Encarnacion, B., Downey, J.R., Peraza, J., Chong, K., Hernandez-Boussard, T., et al. Probiotics improve outcomes after Roux-en-Y gastric bypass surgery: a prospective randomized trial. J. Gastrointest. Surg. 13:7 (2009), 1198–1204.
82. [82] Sanchez, M., Darimont, C., Drapeau, V., Emady-Azar, S., Lepage, M., Rezzonico, E., et al. Effect of Lactobacillus rhamnosus CGMCC1.3724 supplementation on weight loss and maintenance in obese men and women. Br. J. Nutr. 111:8 (2014), 1507–1519.
83. [83] Agustina, R., Kok, F.J., van de Rest, O., Fahmida, U., Firmansyah, A., Lukito, W., et al. Randomized trial of probiotics and calcium on diarrhea and respiratory tract infections in Indonesian children. Pediatrics, 129(5), 2012 e1155–64.
84. [84] Agustina, R.B.-O.I., Lukito, W., Fahmida, U., van de Rest, O., Mb, Zimmermann, Firmansyah, A., Wulanti, R., Albers, R., van den heuvel, E.G., Kok, F.J., Probiotics Lactobacillus reuteri DSM 17938 and Lactobacillus casei CRL 431 modestly increase growth, but not iron and zinc status, among Indonesian children aged 1-6 years. J. Nutr. 143:7 (2013), 1184–1193.
85. [85] Gil-Campos, M., Lopez, M.A., Rodriguez-Benitez, M.V., Romero, J., Roncero, I., Linares, M.D., et al. Lactobacillus fermentum CECT 5716 is safe and well tolerated in infants of 1-6 months of age: a randomized controlled trial. Pharmacol. Res. 65:2 (2012), 231–238.
86. [86] De Micco, I., Mandatao, C., Licenziati, M.R., Vitale, D.F., Veropalumbo, C., Maddaluno, S., et al. A new possible therapeutic strategy in obesity related liver disease: preliminary data with lactobacillus rhamnosus strain GG. 18th National Congress SIGENP Padua Italy, vol. 43, 2011 S397–S8.
87. [87] Mitra, M., Adarsh, E., Narang, A., Agrawal, R., Vaidya, U., Ganguly, S., Safety and tlerance of infant formula contianing probiotics in India: a multicenter randomized controlled trial. 24th European Congress of Perinatal Medicine Florece Italy, vol. 27, 2014, 346.
88. [88] Mugambi, M.N., Musekiwa, A., Lombard, M., Young, T., Blaauw, R., Synbiotics, probiotics or prebiotics in infant formula for full term infants: a systematic review. Nutr. J., 11, 2012, 81.
89. [89] Park, S., Bae, J.H., Probiotics for weight loss: a systematic review and meta-analysis. Nutr. Res. 35:7 (2015), 566–575.
90. [90] Rao, S., Srinivasjois, R., Patole, S., Prebiotic supplementation in full-term neonates: a systematic review of randomized controlled trials. Arch. Pediatr. Adolesc. Med. 163:8 (2009), 755–764.
91. [91] Kaminski, M., Bechmann, I., Pohland, M., Kiwit, J., Nitsch, R., Glumm, J., Migration of monocytes after intracerebral injection at entorhinal cortex lesion site. J. Leukoc. Biol. 92:1 (2012), 31–39.
92. [92] Gough, E.K., Moodie, E.M.M., Prendergast, A.J., Johnson, S.M.A., Humphrey, J.H., Stoltzfus, Rea, The impact of antibiotics on growth in children in low and middle income countries: systematic reivew and meta-analysis of randomised controlled trials. BMJ, 2014, 348.
93. [93] Abely, M., Jubin, V., Bessaci-Kabouya, K., Chiron, R., Bui, S., Fayon, M., National consensus regarding azithromycin use in cystic fibrosis. Rev. Mal. Respir. 32:6 (2015), 557–565.
94. [94] Guzman, M.A., Scrimshaw, N.S., Monroe, R.J., Growth and development of Central American children. I. Growth responses of rural Guatemalan school children to daily administration of penicillin and aureomycin. Am. J. Clin. Nutr. 6:4 (1958), 430–438.
95. [95] Macdougall, L.G., The effect of aureomycin on undernourished African children. J. Trop. Pediatr. (1967) 3:2 (1957), 74–81.
96. [96] Trehan, I., Goldbach, H.S., LaGrone, L.N., Meuli, G.J., Wang, R.J., Maleta, K.M., et al. Antibiotics as part of the management of severe acute malnutrition. N. Engl. J. Med. 368:5 (2013), 425–435.
97. [97] Garrett, W.S., Kwashiorkor and the gut microbiota. N. Engl. J. Med. 368:18 (2013), 1746–1747.
98. [98] Cortopassi, G.A., Wilson, A.C., Recent origin of the P lysozyme gene in mice. Nucleic Acids Res., 18(7), 1990, 1911.
99. [99] Angelakis, E., Million, M., Kankoe, S., Lagier, J.C., Armougom, F., Giorgi, R., et al. Abnormal weight gain and gut microbiota modifications are side effects of long-term doxycycline and hydroxychloroquine treatment. Antimicrob. Agents Chemother. 58:6 (2014), 3342–3347.
100. [100] Million, M., Thuny, F., Angelakis, E., Casalta, J.P., Giorgi, R., Habib, G., et al. Lactobacillus reuteri and Escherichia coli in the human gut microbiota may predict weight gain associated with vancomycin treatment. Nutr. Diabetes, 3, 2013, e87.
101. [101] Park, D.Y., Ahn, Y.T., Park, S.H., Huh, C.S., Yoo, S.R., Yu, R., et al. Supplementation of Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032 in diet-induced obese mice is associated with gut microbial changes and reduction in obesity. PLoS One, 8(3), 2013, e59470.
102. [102] Zhou, T., Schneider, K.E., Li, X.Z., Development of biocontrol agents from food microbial isolates for controlling post-harvest peach brown rot caused by Monilinia fructicola. Int. J. Food Microbiol. 126:1–2 (2008), 180–185.
103. [103] Armougom, F., Henry, M., Vialettes, B., Raccah, D., Raoult, D., Monitoring bacterial community of human gut microbiota reveals an increase in Lactobacillus in obese patients and Methanogens in anorexic patients. PLoS One, 4(9), 2009, e7125.
104. [104] Santacruz, A., Collado, M.C., Garcia-Valdes, L., Segura, M.T., Martin-Lagos, J.A., Anjos, T., et al. Gut microbiota composition is associated with body weight, weight gain and biochemical parameters in pregnant women. Br. J. Nutr. 104:1 (2010), 83–92.
105. [105] Kalliomaki, M., Collado, M.C., Salminen, S., Isolauri, E., Early differences in fecal microbiota composition in children may predict overweight. Am. J. Clin. Nutr. 87:3 (2008), 534–538.
106. [106] Collado, M.C., Isolauri, E., Laitinen, K., Salminen, S., Distinct composition of gut microbiota during pregnancy in overweight and normal-weight women. Am. J. Clin. Nutr. 88:4 (2008), 894–899.
107. [107] Million, M., Angelakis, E., Paul, M., Armougom, F., Leibovici, L., Raoult, D., Comparative meta-analysis of the effect of Lactobacillus species on weight gain in humans and animals. Microb. Pathog. 53:2 (2012), 100–108.
108. [108] Moya-Perez, A., Romo-Vaquero, M., Tomas-Barberan, F., Sanz, Y., Garcia-Conesa, M.T., Hepatic molecular responses to Bifidobacterium pseudocatenulatum CECT 7765 in a mouse model of diet-induced obesity. Nutr. Metab. Cardiovasc Dis. 24:1 (2014), 57–64.
109. [109] Cani, P.D., Amar, J., Iglesias, M.A., Poggi, M., Knauf, C., Bastelica, D., et al. Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes 56:7 (2007), 1761–1772.
110. [110] Amar, J., Chabo, C., Waget, A., Klopp, P., Vachoux, C., Bermudez-Humaran, L.G., et al. Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment. EMBO Mol. Med. 3:9 (2011), 559–572.
111. [111] Festi, D., Schiumerini, R., Eusebi, L.H., Marasco, G., Taddia, M., Colecchia, A., Gut microbiota and metabolic syndrome. World J. Gastroenterol. 20:43 (2014), 16079–16094.