Effects of Bifidobacterium lactis HN019 and prebiotic oligosaccharide added to milk on iron status, anemia, and growth among children 1 to 4 years old

Journal of Pediatric Gastroenterology and Nutrition

Volumn 51, Issue 3, 2010, Pages 341-346

  Sazawal, Sunil ^a   Dhingra, Usha ^a   Hiremath, Girish ^a   Sarkar, Archana ^b   Dhingra, Pratibha ^b   Dutta, Arup ^a   Menon, Venugopal P ^b   Black, Robert E ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b ANNAMALAI UNIVERSITY   (India)

Author keywords

anemia; compliance; fortification; growth; iron status; probiotics

Indexed keywords

OLIGOSACCHARIDE; PREBIOTIC AGENT; PROBIOTIC AGENT;

ANEMIA; ARTICLE; BIFIDOBACTERIUM ANIMALIS; BODY HEIGHT; BODY WEIGHT; CHILD; CLINICAL TRIAL; COLONY FORMING UNIT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; FEMALE; GROWTH CURVE; HEMATOLOGY; HUMAN; IRON DEFICIENCY; IRON STORAGE; MAJOR CLINICAL STUDY; MALE; MILK; PRESCHOOL CHILD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; WEIGHT GAIN;

ANEMIA, IRON-DEFICIENCY; ANIMALS; BIFIDOBACTERIUM; CHILD, PRESCHOOL; DOUBLE-BLIND METHOD; FERRITINS; FOOD, FORTIFIED; GROWTH; HUMANS; INFANT; MILK; MULTIVARIATE ANALYSIS; OLIGOSACCHARIDES; PREBIOTICS; PROBIOTICS; URBAN HEALTH; WEIGHT GAIN;

BIFIDOBACTERIUM ANIMALIS SUBSP. LACTIS;

EID: 77956450903     PISSN: 02772116     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPG.0b013e3181d98e45     Document Type: Article

References (47)

1. Black RE, Allen LH, Bhutta ZA, et al. Maternal and child undernutrition: global and regional exposures and health consequences. Lancet 2008;371:243-60.
2. World Bank Report. India's Undernourished Children: A Call for Reform and Action. Washington, DC: The International Bank for Reconstruction and Development/The World Bank; 2005.
3. Marjan ZM, Taib MNM, Lin KG, et al. Socioeconomic determinants of nutritional status of children in rural peninsular Malaysia. Asia Pac J Clin Nutr 1998;7:307-10.
4. Solis B, Samartin S, Gomez S, et al. Probiotics as a help in children suffering from malnutrition and diarrhoea. Eur J Clin Nutr 2002;56(Suppl 3):S57-9.
5. Yip R. Prevention and control of iron deficiency: policy and strategy issues. J Nutr 2002;132 (Suppl 4):802S-5S.
6. Lozoff B. Iron deficiency and child development. Food Nutr Bull 2007;28(Suppl 4):S560-71.
7. Zlotkin SH, Christofides AL, Hyder SM, et al. Controlling iron deficiency anemia through the use of home-fortified complementary foods. Indian J Pediatr 2004;71:1015-9.
8. Zlotkin S, Arthur P, Schauer C, et al. Home-fortification with iron and zinc sprinkles or iron sprinkles alone successfully treats anemia in infants and young children. J Nutr 2003;133:1075-80.
9. Fischer WC, Kordas K, Stoltzfus RJ, et al. Interactive effects of iron and zinc on biochemical and functional outcomes in supplementation trials. Am J Clin Nutr 2005;82:5-12.
10. Bhandari N, Bahl R, Taneja S. Effect of micronutrient supplementation on linear growth of children. Br J Nutr 2001;85 (Suppl 2):S131-7.
11. Bhandari N, Mazumder S, Bahl R, et al. An educational intervention to promote appropriate complementary feeding practices and physical growth in infants and young children in rural Haryana, India. J Nutr 2004;134:2342-8.
12. Sandstrom B. Micronutrient interactions: effects on absorption and bioavailability. Br J Nutr 2001;85 (Suppl 2):S181-5.
13. Szajewska H, Mrukowicz JZ. Use of probiotics in children with acute diarrhea. Paediatr Drugs 2005;7:111-22.
14. Sazawal S, Hiremath G, Dhingra U, et al. Efficacy of probiotics in prevention of acute diarrhoea: a meta-analysis of masked, randomised, placebo-controlled trials. Lancet Infect Dis 2006;6:374-82.
15. Guandalini S. Probiotics for children with diarrhea: an update. J Clin Gastroenterol 2008;42 (Suppl 2):S53-7.
16. Roberfroid MB. Prebiotics: preferential substrates for specific germs? Am J Clin Nutr 2001;73 (Suppl 2):406S-9S.
17. Saran S, Gopalan S, Krishna TP. Use of fermented foods to combat stunting and failure to thrive. Nutrition 2002;18:393-6.
18. Nopchinda S, Varavithya W, Phuapradit P, et al. Effect of bifidobacterium Bb12 with or without Streptococcus thermophilus supplemented formula on nutritional status. J Med Assoc Thai 2002;85(Suppl 4):S1225-31.
19. Sanders ME. Summary of probiotic activities of Bifidobacterium lactis HN019. J Clin Gastroenterol 2006;40:776-83.
20. Sazawal S, Dhingra U, Hiremath G, et al. Probiotic-prebiotic fortified milk in prevention of morbidities among children: community-based, randomized, double-blind, controlled trial. PLOS One. In press.
21. Sazawal S, Dhingra U, Dhingra P, et al. Effects of fortified milk on morbidity in young children in north India: community based, randomised, double masked placebo controlled trial. BMJ 2007;334:140.
22. Migita M, Fukunaga Y, Yamamoto M. The measurement of zinc protoporphyrin for iron deficiency anemia by hematofluorometer in children. Nippon Ika Daigaku Zasshi 1993;60:105-11.
23. Flowers CH, Kuizon M, Beard JL, et al. A serum ferritin assay for prevalence studies of iron deficiency. Am J Hematol 1986;23:141-51.
24. Flowers CH, Sikikne BS, Covell AM, et al. The clinical measurement of serum transferrin receptor. J Lab Clin Med 1989;144:368-77.
25. WHO Multicentre Growth Reference Study Group.WHOChild Growth Standards: length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: methods and development. http://www.who.int/ childgrowth/publications/en. Accessed May 1, 2009.
26. Joint World Health Organization/Centers for Disease Control and Prevention. Technical Consultation on the Assessment of Iron Status at the Population Level. Geneva: World Health Organization; 2004.
27. Lozoff B, Corapci F, Burden MJ, et al. Preschool-aged children with iron deficiency anemia show altered affect and behavior. J Nutr 2007;137:683-9.
28. Gill HS, Rutherfurd KJ, Prasad J, et al. Enhancement of natural and acquired immunity by Lactobacillus rhamnosus (HN001), Lactobacillus acidophilus (HN017) and Bifidobacterium lactis (HN019). Br J Nutr 2000;83:167-76.
29. Shu Q, Qu F, Gill HS. Probiotic treatment using Bifidobacterium lactis HN019 reduces weanling diarrhea associated with rotavirus and Escherichia coli infection in a piglet model. J Pediatr Gastroenterol Nutr 2001;33:171-7.
30. Shu Q, Gill HS. A dietary probiotic (Bifidobacterium lactis HN019) reduces the severity of Escherichia coli O157:H7 infection in mice. Med Microbiol Immunol 2001;189:147-52.
31. Arunachalam K, Gill HS, Chandra RK. Enhancement of natural immune function by dietary consumption of Bifidobacterium lactis (HN019). Eur J Clin Nutr 2000;54:263-7.
32. Chiang BL, Sheih YH,Wang LH, et al. Enhancing immunity by dietary consumption of a probiotic lactic acid bacterium (Bifidobacterium lactis HN019): optimization and definition of cellular immune responses. Eur J Clin Nutr 2000;54:849-55.
33. Gill HS, Rutherfurd KJ, Cross ML, et al. Enhancement of immunity in the elderly by dietary supplementation with the probiotic Bifidobacterium lactis HN019. Am J Clin Nutr 2001;74:833-9.
34. Branca F, Rossi L. The role of fermented milk in complementary feeding of young children: lessons from transition countries. Eur J Clin Nutr 2002;56(Suppl 4):S16-20.
35. Bezkorovainy A. Probiotics: determinants of survival and growth in the gut. Am J Clin Nutr 2001;73:399S-405S.
36. Vendt N, Grünberg H, Tuure T, et al. Growth during the first 6 months of life in infants using formula enriched with Lactobacillus rhamnosus GG: double-blind, randomized trial. J Hum Nutr Diet 2006;19:51-8.
37. Dewan P, Kaur I, Chattopadhya D, et al. A pilot study on the effects of curd (dahi) and leaf protein concentrate in children with protein energy malnutrition (PEM). Indian J Med Res 2007;126:199-203.
38. Silva MR, Dias G, Ferreira CL, et al. Growth of preschool children was improved when fed an iron-fortified fermented milk beverage supplemented with Lactobacillus acidophilus. Nutr Res 2008;28:226-32.
39. Schrezenmeir J, Heller K, McCue M, et al. Benefits of oral supplementation with and without synbiotics in young children with acute bacterial infections. Clin Pediatr (Phila) 2004;43:239-49.
40. Salvini F, Granieri L, Gemmellaro L, et al. Probiotics, prebiotics and child health: where are we going? J Int Med Res 2004;32:97-108.
41. Saavedra JM, Abi-Hanna A, Moore N, et al. Long-term consumption of infant formulas containing live probiotic bacteria: tolerance and safety. Am J Clin Nutr 2004;79:261-7.
42. Scholz-Ahrens KE, Ade P, Marten B, et al. Prebiotics, probiotics, and synbiotics affect mineral absorption, bone mineral content, and bone structure. J Nutr 2007;137(3 Suppl 2):838S-46S.
43. Kaila M, Isolauri E, Saxelin M, et al. Viableversus inactivatedlactobacillus strain GG in acute rotavirus diarrhoea. Arch Dis Child 1995;72:51-3.
44. Mohammad MA, Molloy A, Scott J, et al. Plasma cobalamin and folate and their metabolic markers methylmalonic acid and total homocysteine among Egyptian children before and after nutritional supplementation with the probiotic bacteria Lactobacillus acidophilus in yoghurt matrix. Int J Food Sci Nutr 2006;57:470-80.
45. Saavedra JM, Tschernia A. Human studies with probiotics and prebiotics: clinical implications. Br J Nutr 2002;87 (Suppl 2):S241-6.
46. Fooks LJ, Gibson GR. Probiotics as modulators of the gut flora. Br J Nutr 2002;88 (Suppl 1):S39-49.
47. Oda T, Kadooka Y, Hashiba H. Effect of Lactobacillus acidophilus on iron bioavailability in rats. J Nutr Sci Vitaminol 1994;40:613-6.