Plasmodium yoelii infection of BALB/c mice results in expansion rather than induction of CD4 + Foxp3 + regulatory T cells

Immunology

Volumn 148, Issue 2, 2016, Pages 197-205

  Abel, Simone ^a   Ueffing, Kristina ^a   Tatura, Roman ^a   Hutzler, Marina ^a   Hose, Matthias ^a   Matuschewski, Kai ^b   Kehrmann, Jan ^a   Westendorf, Astrid M ^a   Buer, Jan ^a   Hansen, Wiebke ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

Author keywords

Parasitic protozoan; Regulatory T cells; Rodent

Indexed keywords

CD4 ANTIGEN; NEUROPILIN 1; T LYMPHOCYTE RECEPTOR BETA CHAIN; TRANSCRIPTION FACTOR FOXP3; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; CELL EXPANSION; CELL POPULATION; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; HISTONE DEMETHYLATION; IMMUNE RESPONSE; MOUSE; NONHUMAN; PLASMODIUM YOELII; PLASMODIUM YOELII INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN METHYLATION; REGULATORY T LYMPHOCYTE; ANIMAL; BAGG ALBINO MOUSE; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; DNA METHYLATION; GENETICS; HUMAN; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MALARIA; METABOLISM;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; DNA METHYLATION; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; LYMPHOCYTE ACTIVATION; MALARIA; MICE; MICE, INBRED BALB C; NEUROPILIN-1; PLASMODIUM YOELII; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTES, REGULATORY;

EID: 84961770648     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12602     Document Type: Article

References (34)

1. Maizels R. Regulation of the immune system in metazoan parasite infections. Novartis Found Symp 2007; 281:192-204.
2. + regulatory T cells in mice infected with the filarial parasite Brugia malayi. J Immunol 2008; 181:6456-66.
3. + regulatory T cells induced by chronic retroviral infection. Proc Natl Acad Sci U S A 2001; 98:9226-30.
4. + ) in the antrum and cardia are associated with higher H. pylori colonization and increased gene expression of TGF-β1. Helicobacter 2008; 13:295-303.
5. + regulatory T cells correlates with more rapid parasite growth in human malaria infection. Immunity 2005; 23:287-96.
6. Minigo G, Woodberry T, Piera KA, Salwati E, Tjitra E, Kenangalem E, Price RN et al. Parasite-dependent expansion of TNF receptor II-positive regulatory T cells with enhanced suppressive activity in adults with severe malaria. PLoS Pathog 2009; 5:e1000402.
7. + regulatory T cells and limited effect of T cell-derived IL-10 on pathogen clearance during Plasmodium yoelii infection. J Immunol 2012; 188:5467-77.
8. Apostolou I, von Boehmer H. In vivo instruction of suppressor commitment in naive T cells. J Exp Med 2004; 199:1401-8.
9. Bruder D, Westendorf AM, Hansen W, Prettin S, Gruber AD, Qian Y, von Boehmer H et al. On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes. Diabetes 2005; 54:3395-401.
10. Hansen W, Westendorf AM, Reinwald S, Bruder D, Deppenmeier S, Groebe L, Probst-Kepper M et al. Chronic antigen stimulation in vivo induces a distinct population of antigen-specific Foxp3 CD25 regulatory T cells. J Immunol 2007; 179:8059-68.
11. Apostolou I, Sarukhan A, Klein L, von Boehmer H. Origin of regulatory T cells with known specificity for antigen. Nat Immunol 2002; 3:756-63.
12. + regulatory T cell repertoire formation shaped by differential presentation of peptides from a self-antigen. J Immunol 2008; 180:2149-57.
13. + regulatory T cells: more of the same or a division of labor? Immunity 2009; 30:626-35.
14. + T regulatory cells. J Immunol 2010; 184:3433-41.
15. Akimova T, Beier UH, Wang L, Levine MH, Hancock WW. Helios expression is a marker of T cell activation and proliferation. PLoS ONE 2011; 6:e24226.
16. + regulatory T cells. J Immunol 2012; 188:976-80.
17. + T reg cells. J Exp Med 2012; 209:1723-42, S1.
18. Yadav M, Louvet C, Davini D, Gardner JM, Martinez-Llordella M, Bailey-Bucktrout S, Anthony BA et al. Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo. J Exp Med 2012; 209:1713-9.
19. Bruder D, Probst-Kepper M, Westendorf AM, Geffers R, Beissert S, Loser K, von Boehmer H et al. Neuropilin-1: a surface marker of regulatory T cells. Eur J Immunol 2004; 34:623-30.
20. Floess S, Freyer J, Siewert C, Baron U, Olek S, Polansky J, Schlawe K et al. Epigenetic control of the foxp3 locus in regulatory T cells. PLoS Biol 2007; 5:e38.
21. Huehn J, Polansky JK, Hamann A. Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage? Nat Rev Immunol 2009; 9:83-9.
22. Polansky JK, Kretschmer K, Freyer J, Floess S, Garbe A, Baron U, Olek S et al. DNA methylation controls Foxp3 gene expression. Eur J Immunol 2008; 38:1654-63.
23. + regulatory T cells for early and late phase of murine sepsis. Immunology 2015; 146:144-56.
24. Greenwood BM, Oduloju AJ, Platts-Mills TA. Partial characterization of a malaria mitogen. Trans R Soc Trop Med Hyg 1979; 73:178-82.
25. Toker A, Engelbert D, Garg G, Polansky JK, Floess S, Miyao T, Baron U et al. Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus. J Immunol 2013; 190:3180-8.
26. + T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells. Immunity 2012; 36:262-75.
27. Petzold C, Steinbronn N, Gereke M, Strasser RH, Sparwasser T, Bruder D, Geffers R et al. Fluorochrome-based definition of naturally occurring Foxp3 regulatory T cells of intra- and extrathymic origin. Eur J Immunol 2014; 44:3632-45.
28. Pied S, Voegtle D, Marussig M, Renia L, Miltgen F, Mazier D, Cazenave PA. Evidence for superantigenic activity during murine malaria infection. Int Immunol 1997; 9:17-25.
29. Swardson CJ, Wassom DL, Avery AC. Plasmodium yoelii: resistance to disease is linked to the mtv-7 locus in BALB/c mice. Exp Parasitol 1997; 86:102-9.
30. Loizon S, Boeuf P, Tetteh JK, Goka B, Obeng-Adjei G, Kurtzhals JA, Rogier C et al. Vβ profiles in African children with acute cerebral or uncomplicated malaria: very focused changes among a remarkable global stability. Microbes Infect 2007; 9:1252-9.
31. Couper KN, Blount DG, Wilson MS, Hafalla JC, Belkaid Y, Kamanaka M, Flavell RA et al. IL-10 from CD4CD25Foxp3CD127 adaptive regulatory T cells modulates parasite clearance and pathology during malaria infection. PLoS Pathog 2008; 4:e1000004.
32. + natural regulatory T cells during retrovirus infection. J Immunol 2013; 190:5485-95.
33. Punkosdy GA, Blain M, Glass DD, Lozano MM, O'Mara L, Dudley JP, Ahmed R et al. Regulatory T-cell expansion during chronic viral infection is dependent on endogenous retroviral superantigens. Proc Natl Acad Sci U S A 2011; 108:3677-82.
34. Singh K, Hjort M, Thorvaldson L, Sandler S. Concomitant analysis of Helios and Neuropilin-1 as a marker to detect thymic derived regulatory T cells in naive mice. Sci Rep 2015; 5:7767.