The tip of the four N-terminal α-helices of Clostridium sordellii lethal toxin contains the interaction site with membrane phosphatidylserine facilitating small GTPases glucosylation

Toxins

Volumn 8, Issue 4, 2016, Pages

  Chavez, Carolina Varela ^a   Haustant, Georges Michel ^a   Baron, Bruno ^a   England, Patrick ^a   Chenal, Alexandre ^a   Pauillac, Serge ^a   Blondel, Arnaud ^a   Popoff, Michel Robert ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

C. sordellii lethal toxin; Clostridium difficile; Clostridium sordellii; Large clostridial glucosylating toxin; Phosphatidylserine; Ras

Indexed keywords

CLOSTRIDIUM SORDELLII LETHAL TOXIN; CLOSTRIDIUM TOXIN; GUANOSINE TRIPHOSPHATASE; PHOSPHATIDYLSERINE; RAC PROTEIN; RAS PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; BACTERIAL TOXIN; LETHAL TOXIN LT, CLOSTRIDIUM SORDELLII; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN BINDING;

ALPHA HELIX; ANIMAL CELL; ARTICLE; BACTERIUM MUTANT; BINDING SITE; CELL PROLIFERATION; CELL VIABILITY; CIRCULAR DICHROISM; CONTROLLED STUDY; ELECTROPORATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIFLUORESCENCE MICROSCOPY; GLYCOSYLATION; HUMAN; HUMAN CELL; INVERSE POLYMERASE CHAIN REACTION; NONHUMAN; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN LOCALIZATION; CELL MEMBRANE; CHEMISTRY; GENETICS; HELA CELL LINE; METABOLISM;

BACTERIAL TOXINS; BINDING SITES; CELL MEMBRANE; GLYCOSYLATION; HELA CELLS; HUMANS; MONOMERIC GTP-BINDING PROTEINS; PHOSPHATIDYLSERINES; PROTEIN BINDING;

EID: 84961671414     PISSN: None     EISSN: 20726651     Source Type: Journal    
DOI: 10.3390/toxins8040090     Document Type: Article

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