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Volumn 283, Issue 1827, 2016, Pages

Adaptive tolerance to a pathogenic fungus drives major histocompatibility complex evolution in natural amphibian populations

Author keywords

Adaptation; Amphibian; Batrachochytrium dendrobatidis; Chytridiomycosis; Immunogenetics; Major histocompatibility complex

Indexed keywords

ADAPTATION; ALLELE; AMPHIBIAN; DISEASE RESISTANCE; EVOLUTIONARY BIOLOGY; FUNGAL DISEASE; FUNGUS; IMMUNITY; MAJOR HISTOCOMPATIBILITY COMPLEX; PATHOGEN; SELECTION; SURVIVAL; TOLERANCE;

EID: 84961653065     PISSN: 09628452     EISSN: 14712954     Source Type: Journal    
DOI: 10.1098/rspb.2015.3115     Document Type: Article
Times cited : (104)

References (74)
  • 1
    • 0034695526 scopus 로고    scopus 로고
    • Emerging infectious diseases of wildlife-threats to biodiversity and human health
    • Daszak P, Cunningham AA, Hyatt AD. 2000 Emerging infectious diseases of wildlife-threats to biodiversity and human health. Science 287, 443-449. (doi:10.1126/science.287.5452.443)
    • (2000) Science , vol.287 , pp. 443-449
    • Daszak, P.1    Cunningham, A.A.2    Hyatt, A.D.3
  • 3
    • 13144266734 scopus 로고    scopus 로고
    • Chytridiomycosis causes amphibian mortality associated with population declines in the rain forests of Australia and Central America
    • Berger L et al. 1998 Chytridiomycosis causes amphibian mortality associated with population declines in the rain forests of Australia and Central America. Proc. Natl Acad. Sci. USA 95, 9031-9036. (doi:10.1073/pnas.95.15.9031)
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 9031-9036
    • Berger, L.1
  • 7
    • 77953093820 scopus 로고    scopus 로고
    • Dynamics of an emerging disease drive large-scale amphibian population extinctions
    • Vredenburg VT, Briggs CJ, Tunstall TS, Knapp RA. 2010 Dynamics of an emerging disease drive large-scale amphibian population extinctions. Proc. Natl Acad. Sci. USA 107, 9689-9694. (doi:10.1073/pnas.0914111107)
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 9689-9694
    • Vredenburg, V.T.1    Briggs, C.J.2    Tunstall, T.S.3    Knapp, R.A.4
  • 8
    • 79954460452 scopus 로고    scopus 로고
    • Integrating species traits with extrinsic threats: Closing the gap between predicting and preventing species declines
    • Murray KA, Rosauer D, McCallum H, Skerratt LF. 2011 Integrating species traits with extrinsic threats: closing the gap between predicting and preventing species declines. Proc. R. Soc. B 278, 1515-1523. (doi:10.1098/rspb.2010.1872)
    • (2011) Proc. R. Soc. B , vol.278 , pp. 1515-1523
    • Murray, K.A.1    Rosauer, D.2    McCallum, H.3    Skerratt, L.F.4
  • 9
    • 78650936448 scopus 로고    scopus 로고
    • Modelling the future distribution of the amphibian chytrid fungus: The influence of climate and human-associated factors
    • Rohr JR, Halstead NT, Raffel TR. 2011 Modelling the future distribution of the amphibian chytrid fungus: the influence of climate and human-associated factors. J. Appl. Ecol. 48, 174-176. (doi:10.1111/j.1365-2664.2010.01891.x)
    • (2011) J. Appl. Ecol , vol.48 , pp. 174-176
    • Rohr, J.R.1    Halstead, N.T.2    Raffel, T.R.3
  • 10
    • 80053629821 scopus 로고    scopus 로고
    • A dilution effect in the emerging amphibian pathogen Batrachochytrium dendrobatidis
    • 326
    • Searle CL, Biga LM, Spatafora JW, Blaustein AR. 2011 A dilution effect in the emerging amphibian pathogen Batrachochytrium dendrobatidis. Proc. Natl Acad. Sci. USA 108, 16 322-16 326. (doi:10.1073/pnas.1108490108)
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , Issue.16 , pp. 322-416
    • Searle, C.L.1    Biga, L.M.2    Spatafora, J.W.3    Blaustein, A.R.4
  • 11
    • 80053627099 scopus 로고    scopus 로고
    • MHC genotypes associate with resistance to a frog-killing fungus
    • 710
    • Savage AE, Zamudio KR. 2011 MHC genotypes associate with resistance to a frog-killing fungus. Proc. Natl Acad. Sci. USA 108, 16 705-16 710. (doi:10.1073/pnas.1106893108)
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , Issue.16 , pp. 705-716
    • Savage, A.E.1    Zamudio, K.R.2
  • 12
    • 79955797813 scopus 로고    scopus 로고
    • Larval fitness and immunogenetic diversity in chytrid-infected and uninfected natterjack toad (Bufo calamita) populations. Conserv
    • May S, Zeisset I, Beebee TJC. 2011 Larval fitness and immunogenetic diversity in chytrid-infected and uninfected natterjack toad (Bufo calamita) populations. Conserv. Genet. 12, 805-811. (doi:10.1007/s10592-011-0187-z)
    • (2011) Genet , vol.12 , pp. 805-811
    • May, S.1    Zeisset, I.2    Beebee, T.J.C.3
  • 13
    • 84885727508 scopus 로고    scopus 로고
    • The invasive chytrid fungus of amphibians paralyzes lymphocyte responses
    • Fites JS et al. 2013 The invasive chytrid fungus of amphibians paralyzes lymphocyte responses. Science 342, 366-369. (doi:10.1126/science.1243316)
    • (2013) Science , vol.342 , pp. 366-369
    • Fites, J.S.1
  • 14
    • 84904194204 scopus 로고    scopus 로고
    • Amphibians acquire resistance to live and dead fungus overcoming fungal immunosuppression
    • McMahon TA et al. 2014 Amphibians acquire resistance to live and dead fungus overcoming fungal immunosuppression. Nature 511, 224-227. (doi:10.1038/nature13491)
    • (2014) Nature , vol.511 , pp. 224-227
    • McMahon, T.A.1
  • 15
    • 84942380023 scopus 로고    scopus 로고
    • Susceptibility of amphibians to chytridiomycosis is associated with MHC class II conformation
    • Bataille A et al. 2015 Susceptibility of amphibians to chytridiomycosis is associated with MHC class II conformation. Proc. R. Soc. B 282, 20143127. (doi:10.1098/rspb.2014.3127)
    • (2015) Proc. R. Soc. B , vol.282
    • Bataille, A.1
  • 16
    • 79957630332 scopus 로고    scopus 로고
    • Disease dynamics vary spatially and temporally in a North American amphibian
    • Savage AE, Sredl MJ, Zamudio KR. 2011 Disease dynamics vary spatially and temporally in a North American amphibian. Biol. Conserv. 144, 1910-1915. (doi:10.1016/j.biocon.2011.03.018)
    • (2011) Biol. Conserv , vol.144 , pp. 1910-1915
    • Savage, A.E.1    Sredl, M.J.2    Zamudio, K.R.3
  • 17
    • 84931827625 scopus 로고    scopus 로고
    • Linking genetic and environmental factors in amphibian disease risk
    • Savage AE, Becker CG, Zamudio KR. 2015 Linking genetic and environmental factors in amphibian disease risk. Evol. Appl. 8, 560-572. (doi:10.1111/eva.12264)
    • (2015) Evol. Appl , vol.8 , pp. 560-572
    • Savage, A.E.1    Becker, C.G.2    Zamudio, K.R.3
  • 18
    • 56249089381 scopus 로고    scopus 로고
    • Evaluating the links between climate, disease spread, and amphibian declines
    • 441
    • Rohr JR, Raffela TR, Romansica JM, McCallum H, Hudson PJ. 2008 Evaluating the links between climate, disease spread, and amphibian declines. Proc. Natl Acad. Sci. USA 105, 17 436-17 441. (doi:10.1073/pnas.0806368105)
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , Issue.17 , pp. 436-517
    • Rohr, J.R.1    Raffela, T.R.2    Romansica, J.M.3    McCallum, H.4    Hudson, P.J.5
  • 20
    • 0034712862 scopus 로고    scopus 로고
    • Primitive synteny of vertebrate major histocompatibility complex class I and class II genes
    • Ohta Y, Okamura K, McKinney E, Bartl S, Hashimoto K, Flajnik MF. 2000 Primitive synteny of vertebrate major histocompatibility complex class I and class II genes. Proc. Natl Acad. Sci. USA 97, 4712-4717. (doi:10.1073/pnas.97.9.4712)
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 4712-4717
    • Ohta, Y.1    Okamura, K.2    McKinney, E.3    Bartl, S.4    Hashimoto, K.5    Flajnik, M.F.6
  • 21
    • 33645290018 scopus 로고    scopus 로고
    • MHC class II proteins and disease: A structural perspective
    • Jones EY, Fugger L, Strominger JL, Siebold C. 2006 MHC class II proteins and disease: a structural perspective. Nat. Rev. Immunol. 6, 271-282. (doi: 10.1038/nri1805)
    • (2006) Nat. Rev. Immunol , vol.6 , pp. 271-282
    • Jones, E.Y.1    Fugger, L.2    Strominger, J.L.3    Siebold, C.4
  • 22
    • 0037884727 scopus 로고    scopus 로고
    • MHC studies in nonmodel vertebrates: What have we learned about natural selection in 15 years
    • Bernatchez L, Landry C. 2003 MHC studies in nonmodel vertebrates: what have we learned about natural selection in 15 years? J. Evol. Biol. 16, 363-377. (doi:10.1046/j.1420-9101.2003.00531.x)
    • (2003) J. Evol. Biol , vol.16 , pp. 363-377
    • Bernatchez, L.1    Landry, C.2
  • 23
    • 10344227722 scopus 로고    scopus 로고
    • An update of the HLA genomic region, locus information and disease associations: 2004
    • Shiina T, Inoko H, Kulski JK. 2004 An update of the HLA genomic region, locus information and disease associations: 2004. Tissue Ant. 64, 631-649. (doi:10.1111/j.1399-0039.2004.00327.x)
    • (2004) Tissue Ant , vol.64 , pp. 631-649
    • Shiina, T.1    Inoko, H.2    Kulski, J.K.3
  • 25
    • 0023653851 scopus 로고
    • Class discrimination in the world of immunology
    • Bevan MJ. 1987 Class discrimination in the world of immunology. Nature 325, 192-194. (doi:10.1038/325192b0)
    • (1987) Nature , vol.325 , pp. 192-194
    • Bevan, M.J.1
  • 26
    • 0040771786 scopus 로고
    • Nucleotide substitution at major histocompatibility complex class II loci: Evidence for overdominant selection
    • Hughes AL, Nei M. 1989 Nucleotide substitution at major histocompatibility complex class II loci: evidence for overdominant selection. Proc. Natl Acad. Sci. USA 86, 948-962. (doi:10.1073/pnas.86.3.958)
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 948-962
    • Hughes, A.L.1    Nei, M.2
  • 27
    • 0016842119 scopus 로고
    • Enhanced immunological surveillance in mice heterozygous at the H-2 gene complex
    • Doherty P, Zinkernagel R. 1975 Enhanced immunological surveillance in mice heterozygous at the H-2 gene complex. Nature 256, 50-52. (doi:10.1038/256050a0)
    • (1975) Nature , vol.256 , pp. 50-52
    • Doherty, P.1    Zinkernagel, R.2
  • 28
    • 84865350067 scopus 로고    scopus 로고
    • Evidence for directional selection at a novel major histocompatibility class I marker in wild common frogs (Rana temporaria) exposed to a viral pathogen (Ranavirus)
    • Teacher AGF, Garner TWJ, Nichols RA. 2009 Evidence for directional selection at a novel major histocompatibility class I marker in wild common frogs (Rana temporaria) exposed to a viral pathogen (Ranavirus). PLoS ONE 4, e4616. (doi:10.1371/journal.pone.0004616)
    • (2009) Plos ONE , vol.4
    • Teacher, A.1    Garner, T.2    Nichols, R.A.3
  • 29
    • 60149105525 scopus 로고    scopus 로고
    • Balancing and directional selection at exon-2 of the MHC DQB1 locus among populations of odontocete cetaceans
    • Vassilakos D, Natoli A, Dahlheim M, Hoelzel AR. 2009 Balancing and directional selection at exon-2 of the MHC DQB1 locus among populations of odontocete cetaceans. Mol. Biol. Evol. 26, 681-689. (doi:10.1093/molbev/msn296)
    • (2009) Mol. Biol. Evol , vol.26 , pp. 681-689
    • Vassilakos, D.1    Natoli, A.2    Dahlheim, M.3    Hoelzel, A.R.4
  • 30
    • 0027065953 scopus 로고
    • Parasites and sex: Catching the Red Queen
    • Ladle R. 1992 Parasites and sex: catching the Red Queen. Trends Ecol. Evol. 7, 405-408. (doi:10.1016/0169-5347(92)90021-3)
    • (1992) Trends Ecol. Evol , vol.7 , pp. 405-408
    • Ladle, R.1
  • 31
    • 0014029675 scopus 로고
    • Maintenance of histocompatibility polymorphisms
    • Clarke B, Kirby D. 1966 Maintenance of histocompatibility polymorphisms. Nature 211, 999-1000. (doi:10.1038/211999a0)
    • (1966) Nature , vol.211 , pp. 999-1000
    • Clarke, B.1    Kirby, D.2
  • 32
    • 0034744361 scopus 로고    scopus 로고
    • How selection shapes variation of the human major histocompatibility complex: A review
    • Meyer D, Thomson G. 2001 How selection shapes variation of the human major histocompatibility complex: a review. Ann. Hum. Genet. 65, 1-26. (doi:10.1046/j.1469-1809.2001.6510001.x)
    • (2001) Ann. Hum. Genet , vol.65 , pp. 1-26
    • Meyer, D.1    Thomson, G.2
  • 33
    • 0031918872 scopus 로고    scopus 로고
    • The immunogenetics of human infectious diseases
    • Hill AVS. 1998 The immunogenetics of human infectious diseases. Ann. Rev. Immunol. 16, 593-617. (doi:10.1146/annurev.immunol.16.1.593)
    • (1998) Ann. Rev. Immunol , vol.16 , pp. 593-617
    • Hill, A.V.S.1
  • 34
    • 0036807185 scopus 로고    scopus 로고
    • Pathogen resistance and genetic variation at MHC loci
    • Hedrick P. 2002 Pathogen resistance and genetic variation at MHC loci. Evolution 56, 1902-1908. (doi:10.1111/j.0014-3820.2002.tb00116.x)
    • (2002) Evolution , vol.56 , pp. 1902-1908
    • Hedrick, P.1
  • 35
    • 0022388317 scopus 로고
    • Xenopus MHC class II molecules. I. Identification and structural characterization
    • Kaufman JF, Flajnik MF, Du Pasquier L, Riegert P. 1985 Xenopus MHC class II molecules. I. Identification and structural characterization. J. Immunol. 134, 3248-3257.
    • (1985) J. Immunol , vol.134 , pp. 3248-3257
    • Kaufman, J.F.1    Flajnik, M.F.2    Du Pasquier, L.3    Riegert, P.4
  • 36
    • 0025195139 scopus 로고
    • The major histocompatibility complex of frogs
    • Flajnik MF, Du Pasquier L. 1990 The major histocompatibility complex of frogs. Immunol. Rev. 113, 47-63. (doi:10.1111/j.1600-065X.1990.tb00036.x)
    • (1990) Immunol. Rev , vol.113 , pp. 47-63
    • Flajnik, M.F.1    Du Pasquier, L.2
  • 37
    • 33644840190 scopus 로고    scopus 로고
    • Ancestral organization of the MHC revealed in the amphibian Xenopus
    • Ohta Y, Goetz W, Hossain MZ, Nonaka M, Flajnik MF. 2006 Ancestral organization of the MHC revealed in the amphibian Xenopus. J. Immunol. 176, 3674-3685. (doi:10.4049/jimmunol.176.6.3674)
    • (2006) J. Immunol , vol.176 , pp. 3674-3685
    • Ohta, Y.1    Goetz, W.2    Hossain, M.Z.3    Nonaka, M.4    Flajnik, M.F.5
  • 38
    • 0030992493 scopus 로고    scopus 로고
    • Major histocompatibility complex gene mapping in the amphibian Xenopus implies a primordial organization
    • Nonaka M, Namikawa C, Kato Y, Sasaki M, Salter-Cid L, Flajnik MF. 1997 Major histocompatibility complex gene mapping in the amphibian Xenopus implies a primordial organization. Proc. Natl Acad. Sci. USA 94, 5789-5791. (doi:10.1073/pnas.94.11.5789)
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 5789-5791
    • Nonaka, M.1    Namikawa, C.2    Kato, Y.3    Sasaki, M.4    Salter-Cid, L.5    Flajnik, M.F.6
  • 39
    • 0032899875 scopus 로고    scopus 로고
    • Insight into the primordial MHC from studies in ectothermic vertebrates
    • Flajnik MF, Ohta Y, Namikawa-Yamada C, Nonaka M. 1999 Insight into the primordial MHC from studies in ectothermic vertebrates. Immunol. Rev. 167, 59-67. (doi:10.1111/j.1600-065X.1999.tb01382.x)
    • (1999) Immunol. Rev , vol.167 , pp. 59-67
    • Flajnik, M.F.1    Ohta, Y.2    Namikawa-Yamada, C.3    Nonaka, M.4
  • 40
    • 80052717965 scopus 로고    scopus 로고
    • A large-scale phylogeny of Amphibia including over 2,800 species, and a revised classification of extant frogs, salamanders, and caecilians
    • Pyron RA, Wiens JJ. 2011 A large-scale phylogeny of Amphibia including over 2,800 species, and a revised classification of extant frogs, salamanders, and caecilians. Mol. Phylog. Evol. 61, 543-583. (doi:10.1016/j.ympev.2011.06.012)
    • (2011) Mol. Phylog. Evol , vol.61 , pp. 543-583
    • Pyron, R.A.1    Wiens, J.J.2
  • 41
    • 77949284466 scopus 로고    scopus 로고
    • Expression profiling the temperature-dependent amphibian response to infection by Batrachochytrium dendrobatidis
    • Ribas L et al. 2009 Expression profiling the temperature-dependent amphibian response to infection by Batrachochytrium dendrobatidis. PLoS ONE 4, e8408. (doi:10.1371/journal.pone.0008408)
    • (2009) Plos ONE , vol.4
    • Ribas, L.1
  • 42
    • 84862732420 scopus 로고    scopus 로고
    • Only skin deep: Shared genetic response to the deadly chytrid fungus in susceptible frog species
    • Rosenblum ET, Poorten TJ, Settles M, Murdoch GK. 2012 Only skin deep: shared genetic response to the deadly chytrid fungus in susceptible frog species. Mol. Ecol. 21, 2110-3120. (doi:10.1111/j.1365-294X.2012.05481.x)
    • (2012) Mol. Ecol , vol.21 , pp. 2110-3120
    • Rosenblum, E.T.1    Poorten, T.J.2    Settles, M.3    Murdoch, G.K.4
  • 43
    • 84925286743 scopus 로고    scopus 로고
    • Fighting a losing battle: Vigorous immune response countered by pathogen suppression of host defenses in a chytridiomycosis-susceptible
    • Ellison AR, Savage AE, DiRenzo GV, Langhammer P, Lips KR, Zamudio KR. 2014 Fighting a losing battle: vigorous immune response countered by pathogen suppression of host defenses in a chytridiomycosis-susceptible Frog. G3 4, 1275-1289. (doi:10.1534/g3.114.010744)
    • (2014) Frog , vol.3 , Issue.4 , pp. 1275-1289
    • Ellison, A.R.1    Savage, A.E.2    Direnzo, G.V.3    Langhammer, P.4    Lips, K.R.5    Zamudio, K.R.6
  • 44
    • 84928265473 scopus 로고    scopus 로고
    • More than skin deep: Functional genomic basis for resistance to amphibian chytridiomycosis
    • Ellison AR et al. 2015 More than skin deep: functional genomic basis for resistance to amphibian chytridiomycosis. Genome Biol. Evol. 7, 286-298. (doi:10.1093/gbe/evu285)
    • (2015) Genome Biol. Evol , vol.7 , pp. 286-298
    • Ellison, A.R.1
  • 45
    • 34247637973 scopus 로고    scopus 로고
    • Molecular characterization of MHC class II in a nonmodel anuran species, the fire-bellied toad Bombina bombina
    • Hauswaldt JS, Stuckas H, Pfautsch S, Tiedemann R. 2007 Molecular characterization of MHC class II in a nonmodel anuran species, the fire-bellied toad Bombina bombina. Immunogenetics 59, 479-491. (doi:10.1007/s00251-007-0210-1)
    • (2007) Immunogenetics , vol.59 , pp. 479-491
    • Hauswaldt, J.S.1    Stuckas, H.2    Pfautsch, S.3    Tiedemann, R.4
  • 46
    • 78649319665 scopus 로고    scopus 로고
    • Selection, trans-species polymorphism and locus identification of major histocompatibility complex class IIb alleles of New World ranid frogs
    • Kiemnec-Tyburczy KM, Richmond JQ, Savage AE, Zamudio KR. 2010 Selection, trans-species polymorphism and locus identification of major histocompatibility complex class IIb alleles of New World ranid frogs. Immunogenetics 62, 741-751. (doi:10.1007/s00251-010-0476-6)
    • (2010) Immunogenetics , vol.62 , pp. 741-751
    • Kiemnec-Tyburczy, K.M.1    Richmond, J.Q.2    Savage, A.E.3    Zamudio, K.R.4
  • 48
    • 0000262278 scopus 로고
    • GENEPOP: Population genetics software for exact tests and ecumenicism
    • Raymond M, Rousset F. 1995 GENEPOP: population genetics software for exact tests and ecumenicism. J. Hered. 86, 248-249.
    • (1995) J. Hered , vol.86 , pp. 248-249
    • Raymond, M.1    Rousset, F.2
  • 49
    • 33847009097 scopus 로고    scopus 로고
    • Diagnostic assays and sampling protocols for the detection of Batrachochytrium dendrobatidis
    • Hyatt AD et al. 2007 Diagnostic assays and sampling protocols for the detection of Batrachochytrium dendrobatidis. Dis. Aquat. Org. 73, 175-192. (doi:10.3354/dao073175)
    • (2007) Dis. Aquat. Org , vol.73 , pp. 175-192
    • Hyatt, A.D.1
  • 50
    • 0001072895 scopus 로고
    • The use of confidence or fiducial limits illustrated in the case of the binomial
    • Clopper C, Pearson S. 1934 The use of confidence or fiducial limits illustrated in the case of the binomial. Biometrika 26, 404-413. (doi:10.1093/biomet/26.4.404)
    • (1934) Biometrika , vol.26 , pp. 404-413
    • Clopper, C.1    Pearson, S.2
  • 51
    • 58949089268 scopus 로고    scopus 로고
    • Isolation and characterization of microsatellite markers in the lowland leopard frog (Rana yavapaiensis) and the relict leopard frog (R. Onca), two declining frogs of the North American desert southwest
    • Savage AE, Jaeger JR. 2009 Isolation and characterization of microsatellite markers in the lowland leopard frog (Rana yavapaiensis) and the relict leopard frog (R. onca), two declining frogs of the North American desert southwest. Mol. Ecol. Res. 9, 199-202. (doi:10.1111/j.1755-0998.2008.02343.x)
    • (2009) Mol. Ecol. Res , vol.9 , pp. 199-202
    • Savage, A.E.1    Jaeger, J.R.2
  • 52
    • 0026689178 scopus 로고
    • Performing the exact test of Hardy-Weinberg proportion for multiple alleles
    • Guo SW, Thompson EA. 1992 Performing the exact test of Hardy-Weinberg proportion for multiple alleles. Biometrics 48, 361-372. (doi:10.2307/2532296)
    • (1992) Biometrics , vol.48 , pp. 361-372
    • Guo, S.W.1    Thompson, E.A.2
  • 54
    • 45849154165 scopus 로고    scopus 로고
    • JModelTest: Phylogenetic model averaging
    • Posada D. 2008 jModelTest: phylogenetic model averaging. Mol. Biol. Evol. 25, 1253-1256. (doi:10.1093/molbev/msn083)
    • (2008) Mol. Biol. Evol , vol.25 , pp. 1253-1256
    • Posada, D.1
  • 55
    • 0041386108 scopus 로고    scopus 로고
    • MrBayes 3: Bayesian phylogenetic inference under mixed models
    • Ronquist F, Huelsenbeck JP. 2003 MrBayes 3: Bayesian phylogenetic inference under mixed models. Bioinformatics 19, 1572-1574. (doi:10.1093/bioinformatics/btg180)
    • (2003) Bioinformatics , vol.19 , pp. 1572-1574
    • Ronquist, F.1    Huelsenbeck, J.P.2
  • 56
    • 15844406550 scopus 로고    scopus 로고
    • HyPhy: Hypothesis testing using phylogenies
    • Kosakovsky Pond SL, Frost SDW, Muse SV. 2005 HyPhy: Hypothesis testing using phylogenies. Bioinformatics 21, 6760-6779. (doi:10.1093/bioinformatics/bti079)
    • (2005) Bioinformatics , vol.21 , pp. 6760-6779
    • Kosakovsky Pond, S.L.1    Frost, S.2    Muse, S.V.3
  • 57
    • 33749827106 scopus 로고    scopus 로고
    • Robust inference of positive selection from recombining coding sequences
    • Scheffler K, Martin DP, Seoighe C. 2006 Robust inference of positive selection from recombining coding sequences. Bioinformatics 22, 2493-2499. (doi:10.1093/bioinformatics/btl427)
    • (2006) Bioinformatics , vol.22 , pp. 2493-2499
    • Scheffler, K.1    Martin, D.P.2    Seoighe, C.3
  • 59
    • 17744396121 scopus 로고    scopus 로고
    • Not so different after all: Comparison of various methods for detecting amino-acid sites under selection
    • Kosakovsky Pond SL, Frost SDW. 2005 Not so different after all: comparison of various methods for detecting amino-acid sites under selection. Mol. Biol. Evol. 22, 1208-1222. (doi:10.1093/molbev/msi105)
    • (2005) Mol. Biol. Evol , vol.22 , pp. 1208-1222
    • Kosakovsky Pond, S.L.1    Frost, S.D.W.2
  • 60
    • 77957919360 scopus 로고    scopus 로고
    • Discriminant analysis of principal components: A new method for the analysis of genetically structured populations
    • Jombart T, Devillard S, Balloux F. 2010 Discriminant analysis of principal components: a new method for the analysis of genetically structured populations. BMC Genet. 11, 94. (doi:10.1186/1471-2156-11-94)
    • (2010) BMC Genet , vol.11
    • Jombart, T.1    Devillard, S.2    Balloux, F.3
  • 61
    • 0032474777 scopus 로고    scopus 로고
    • New chemical descriptors relevant for the design of biologically active peptides. A multivariate characterization of 87 amino acids
    • Sandberg M, Eriksson L, Jonsson J, Sjostrom M, Wold S. 1998 New chemical descriptors relevant for the design of biologically active peptides. A multivariate characterization of 87 amino acids. J. Med. Chem. 41, 2481-2491. (doi:10.1021/jm9700575)
    • (1998) J. Med. Chem , vol.41 , pp. 2481-2491
    • Sandberg, M.1    Eriksson, L.2    Jonsson, J.3    Sjostrom, M.4    Wold, S.5
  • 62
    • 77953067304 scopus 로고    scopus 로고
    • SMOGD: Software for the measurement of genetic diversity
    • Crawford NG. 2010 SMOGD: Software for the measurement of genetic diversity. Mol. Ecol. Res. 10, 556-557. (doi:10.1111/j.1755-0998.2009.02801.x)
    • (2010) Mol. Ecol. Res , vol.10 , pp. 556-557
    • Crawford, N.G.1
  • 63
    • 51649095312 scopus 로고    scopus 로고
    • GST and its relatives do not measure differentiation
    • Jost LOU. 2008 GST and its relatives do not measure differentiation. Mol. Ecol. 17, 4015-4026. (doi:10.1111/j.1365-294X.2008.03887.x)
    • (2008) Mol. Ecol , vol.17 , pp. 4015-4026
    • Jost, L.O.U.1
  • 64
    • 77953032930 scopus 로고    scopus 로고
    • Arlequin suite ver 3.5: A new series of programs to perform population genetics analyses under Linux and Windows
    • Excoffier L, Lischer HEL. 2010 Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Mol. Ecol. Res. 10, 564-567. (doi:10.1111/j.1755-0998.2010.02847.x)
    • (2010) Mol. Ecol. Res , vol.10 , pp. 564-567
    • Excoffier, L.1    Lischer, H.E.L.2
  • 66
    • 84918743166 scopus 로고
    • Influential observations in linear regression
    • Cook RD. 1979 Influential observations in linear regression. J. Am. Stat. Assoc. 74, 169-174. (doi:10.2307/2286747)
    • (1979) J. Am. Stat. Assoc , vol.74 , pp. 169-174
    • Cook, R.D.1
  • 67
    • 41849098071 scopus 로고    scopus 로고
    • Epidemiologic analysis of factors associated with local disappearances of native ranid frogs in Arizona. Conserv
    • Witte CL, Sredl MJ, Kane AS, Hungerford LL. 2008 Epidemiologic analysis of factors associated with local disappearances of native ranid frogs in Arizona. Conserv. Biol. 22, 375-383. (doi:10.1111/j.1523-1739.2007.00878.x)
    • (2008) Biol , vol.22 , pp. 375-383
    • Witte, C.L.1    Sredl, M.J.2    Kane, A.S.3    Hungerford, L.L.4
  • 68
    • 0034120188 scopus 로고    scopus 로고
    • Influence of HLA supertypes on susceptibility and resistance to human immunodeficiency virus type 1 infection
    • MacDonald KS et al. 2000 Influence of HLA supertypes on susceptibility and resistance to human immunodeficiency virus type 1 infection. J. Infect. Dis. 181, 1581-1589. (doi:10.1086/315472)
    • (2000) J. Infect. Dis , vol.181 , pp. 1581-1589
    • Macdonald, K.S.1
  • 69
    • 69549110251 scopus 로고    scopus 로고
    • On the origin and spread of an adaptive allele in deer mice
    • Linnen CR, Kingsley EP, Jensen JD, Hoekstra HE. 2009 On the origin and spread of an adaptive allele in deer mice. Science 325, 1095-1098. (doi:10.1126/science.1175826)
    • (2009) Science , vol.325 , pp. 1095-1098
    • Linnen, C.R.1    Kingsley, E.P.2    Jensen, J.D.3    Hoekstra, H.E.4
  • 70
    • 84856700596 scopus 로고    scopus 로고
    • Rapid and adaptive evolution of MHC genes under parasite selection in experimental vertebrate populations
    • Eizaguirre C, Lenz TL, Kalbe M, Milinski M. 2012 Rapid and adaptive evolution of MHC genes under parasite selection in experimental vertebrate populations. Nat. Comm. 3, 621. (doi:10.1038/ncomms1632)
    • (2012) Nat. Comm , vol.3 , pp. 621
    • Eizaguirre, C.1    Lenz, T.L.2    Kalbe, M.3    Milinski, M.4
  • 71
    • 12444253043 scopus 로고    scopus 로고
    • Association between MHC Class II DRB alleles and parasite load in the hairy-footed gerbil, Gerbillurus paeba, in the Southern Kalahari
    • Harf R, Sommer S. 2005 Association between MHC Class II DRB alleles and parasite load in the hairy-footed gerbil, Gerbillurus paeba, in the Southern Kalahari. Mol. Ecol. 14, 85-91. (doi:10.1111/j.1365-294X.2004.02402.x)
    • (2005) Mol. Ecol. , vol.14 , pp. 85-91
    • Harf, R.1    Sommer, S.2
  • 72
    • 0032584199 scopus 로고    scopus 로고
    • Major histocompatibility complex variation associated with juvenile survival and parasite resistance in a large unmanaged ungulate population (Ovis aries L.)
    • Paterson S, Wilson K, Pemberton J. 1998 Major histocompatibility complex variation associated with juvenile survival and parasite resistance in a large unmanaged ungulate population (Ovis aries L.). Proc. Natl Acad. Sci. USA 95, 3714-3719. (doi:10.1073/pnas.95.7.3714)
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 3714-3719
    • Paterson, S.1    Wilson, K.2    Pemberton, J.3
  • 73
    • 80053243192 scopus 로고    scopus 로고
    • Amphibian immune defenses against chytridiomycosis: Impacts of changing environments
    • Rollins-Smith LA, Ramsey JP, Pask JD, Woodhams DC. 2011 Amphibian immune defenses against chytridiomycosis: impacts of changing environments. Int. Comp. Biol. 51, 552-562. (doi:10.1093/icb/icr095)
    • (2011) Int. Comp. Biol , vol.51 , pp. 552-562
    • Rollins-Smith, L.A.1    Ramsey, J.P.2    Pask, J.D.3    Woodhams, D.C.4
  • 74
    • 84923810602 scopus 로고    scopus 로고
    • Widespread presence of the pathogenic fungus Batrachochytrium dendrobatidis in wild amphibian communities in Madagascar
    • Bletz MC et al. 2015 Widespread presence of the pathogenic fungus Batrachochytrium dendrobatidis in wild amphibian communities in Madagascar. Sci. Rep. 5, 8633. (doi:10.1038/srep08633)
    • (2015) Sci. Rep , vol.5
    • Bletz, M.C.1


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