-
1
-
-
84940778278
-
Incidence and predictors of adverse drug events in an African cohort of HIV-infected adults treated with efavirenz
-
Abah, I. O., Akanbi, M., Abah, M. E., Finangwai, A. I., Dady, C. W., Falang, K. D., et al. (2015). Incidence and predictors of adverse drug events in an African cohort of HIV-infected adults treated with efavirenz. Germs 5, 83-91. doi: 10.11599/germs.2015.1075.
-
(2015)
Germs
, vol.5
, pp. 83-91
-
-
Abah, I.O.1
Akanbi, M.2
Abah, M.E.3
Finangwai, A.I.4
Dady, C.W.5
Falang, K.D.6
-
2
-
-
0032441604
-
Efavirenz
-
Discussion: 1065-1056
-
Adkins, J. C., and Noble, S. (1998). Efavirenz. Drugs 56, 1055-1064, Discussion: 1065-1056. doi: 10.2165/00003495-199856060-00014.
-
(1998)
Drugs
, vol.56
, pp. 1055-1064
-
-
Adkins, J.C.1
Noble, S.2
-
3
-
-
67349205036
-
Pharmacogenetics-based population pharmacokinetic analysis of efavirenz in HIV-1-infected individuals
-
Arab-Alameddine, M., Di Iulio, J., Buclin, T., Rotger, M., Lubomirov, R., Cavassini, M., et al. (2009). Pharmacogenetics-based population pharmacokinetic analysis of efavirenz in HIV-1-infected individuals. Clin. Pharmacol. Ther. 85, 485-494. doi: 10.1038/clpt.2008.271.
-
(2009)
Clin. Pharmacol. Ther
, vol.85
, pp. 485-494
-
-
Arab-Alameddine, M.1
Di Iulio, J.2
Buclin, T.3
Rotger, M.4
Lubomirov, R.5
Cavassini, M.6
-
4
-
-
79956364942
-
Identification of human UGT isoforms responsible for glucuronidation of efavirenz and its three hydroxy metabolites
-
Bae, S. K., Jeong, Y. J., Lee, C., and Liu, K. H. (2011). Identification of human UGT isoforms responsible for glucuronidation of efavirenz and its three hydroxy metabolites. Xenobiotica 41, 437-444. doi: 10.3109/00498254.2011.551849.
-
(2011)
Xenobiotica
, vol.41
, pp. 437-444
-
-
Bae, S.K.1
Jeong, Y.J.2
Lee, C.3
Liu, K.H.4
-
5
-
-
84942983022
-
Markov model for characterizing neuropsychologic impairment and Monte Carlo simulation for optimizing efavirenz therapy
-
Bisaso, K. R., Mukonzo, J. K., and Ette, E. I. (2015). Markov model for characterizing neuropsychologic impairment and Monte Carlo simulation for optimizing efavirenz therapy. J. Clin. Pharmacol. 55, 1229-1235. doi: 10.1002/jcph.533.
-
(2015)
J. Clin. Pharmacol
, vol.55
, pp. 1229-1235
-
-
Bisaso, K.R.1
Mukonzo, J.K.2
Ette, E.I.3
-
6
-
-
83755183491
-
Exploration of CYP450 and drug transporter genotypes and correlations with nevirapine exposure in Malawians
-
Brown, K. C., Hosseinipour, M. C., Hoskins, J. M., Thirumaran, R. K., Tien, H. C., Weigel, R., et al. (2012). Exploration of CYP450 and drug transporter genotypes and correlations with nevirapine exposure in Malawians. Pharmacogenomics 13, 113-121. doi: 10.2217/pgs.11.132.
-
(2012)
Pharmacogenomics
, vol.13
, pp. 113-121
-
-
Brown, K.C.1
Hosseinipour, M.C.2
Hoskins, J.M.3
Thirumaran, R.K.4
Tien, H.C.5
Weigel, R.6
-
7
-
-
33644910426
-
Interpatient variability in the pharmacokinetics of the HIV non-nucleoside reverse transcriptase inhibitor efavirenz: the effect of gender, race, and CYP2B6 polymorphism
-
Burger, D., van der Heiden, I., La Porte, C., van der Ende, M., Groeneveld, P., Richter, C., et al. (2006). Interpatient variability in the pharmacokinetics of the HIV non-nucleoside reverse transcriptase inhibitor efavirenz: the effect of gender, race, and CYP2B6 polymorphism. Br. J. Clin. Pharmacol. 61, 148-154. doi: 10.1111/j.1365-2125.2005.02536.x.
-
(2006)
Br. J. Clin. Pharmacol
, vol.61
, pp. 148-154
-
-
Burger, D.1
van der Heiden, I.2
La Porte, C.3
van der Ende, M.4
Groeneveld, P.5
Richter, C.6
-
8
-
-
77957338981
-
No evidence for induction of ABC transporters in peripheral blood mononuclear cells in humans after 14 days of efavirenz treatment
-
Burhenne, J., Matthée, A. K., Pasáková, I., Röder, C., Heinrich, T., Haefeli, W. E., et al. (2010). No evidence for induction of ABC transporters in peripheral blood mononuclear cells in humans after 14 days of efavirenz treatment. Antimicrob. Agents Chemother. 54, 4185-4191. doi: 10.1128/AAC.00283-10.
-
(2010)
Antimicrob. Agents Chemother
, vol.54
, pp. 4185-4191
-
-
Burhenne, J.1
Matthée, A.K.2
Pasáková, I.3
Röder, C.4
Heinrich, T.5
Haefeli, W.E.6
-
9
-
-
21744451835
-
Antimalarial artemisinin drugs induce cytochrome P450 and MDR1 expression by activation of xenosensors pregnane X receptor and constitutive androstane receptor
-
Burk, O., Arnold, K. A., Nussler, A. K., Schaeffeler, E., Efimova, E., Avery, B. A., et al. (2005). Antimalarial artemisinin drugs induce cytochrome P450 and MDR1 expression by activation of xenosensors pregnane X receptor and constitutive androstane receptor. Mol. Pharmacol. 67, 1954-1965. doi: 10.1124/mol.104.009019.
-
(2005)
Mol. Pharmacol
, vol.67
, pp. 1954-1965
-
-
Burk, O.1
Arnold, K.A.2
Nussler, A.K.3
Schaeffeler, E.4
Efimova, E.5
Avery, B.A.6
-
10
-
-
67649960169
-
Influence of the cytochrome P450 2B6 genotype on population pharmacokinetics of efavirenz in human immunodeficiency virus patients
-
Cabrera, S. E., Santos, D., Valverde, M. P., Domínguez-Gil, A., Gonzalez, F., Luna, G., et al. (2009). Influence of the cytochrome P450 2B6 genotype on population pharmacokinetics of efavirenz in human immunodeficiency virus patients. Antimicrob. Agents Chemother. 53, 2791-2798. doi: 10.1128/AAC.01537-08.
-
(2009)
Antimicrob. Agents Chemother
, vol.53
, pp. 2791-2798
-
-
Cabrera, S.E.1
Santos, D.2
Valverde, M.P.3
Domínguez-Gil, A.4
Gonzalez, F.5
Luna, G.6
-
11
-
-
34547229756
-
The safety and efficacy of tenofovir DF in combination with lamivudine and efavirenz through 6 years in antiretroviral-naive HIV-1-infected patients
-
Cassetti, I., Madruga, J. V., Suleiman, J. M., Etzel, A., Zhong, L., Cheng, A. K., et al. (2007). The safety and efficacy of tenofovir DF in combination with lamivudine and efavirenz through 6 years in antiretroviral-naive HIV-1-infected patients. HIV Clin. Trials 8, 164-172. doi: 10.1310/hct0803-164.
-
(2007)
HIV Clin. Trials
, vol.8
, pp. 164-172
-
-
Cassetti, I.1
Madruga, J.V.2
Suleiman, J.M.3
Etzel, A.4
Zhong, L.5
Cheng, A.K.6
-
12
-
-
73549123640
-
Nevirapine-induced hepatotoxicity and pharmacogenetics: a retrospective study in a population from Mozambique
-
Ciccacci, C., Borgiani, P., Ceffa, S., Sirianni, E., Marazzi, M. C., Altan, A. M., et al. (2010). Nevirapine-induced hepatotoxicity and pharmacogenetics: a retrospective study in a population from Mozambique. Pharmacogenomics 11, 23-31. doi: 10.2217/pgs.09.142.
-
(2010)
Pharmacogenomics
, vol.11
, pp. 23-31
-
-
Ciccacci, C.1
Borgiani, P.2
Ceffa, S.3
Sirianni, E.4
Marazzi, M.C.5
Altan, A.M.6
-
13
-
-
84932117610
-
Pharmacogenetics of CYP2B6, CYP2A6 and UGT2B7 in HIV treatment in African populations: focus on efavirenz and nevirapine
-
Colic, A., Alessandrini, M., and Pepper, M. S. (2015). Pharmacogenetics of CYP2B6, CYP2A6 and UGT2B7 in HIV treatment in African populations: focus on efavirenz and nevirapine. Drug Metab. Rev. 47, 111-123. doi: 10.3109/03602532.2014.982864.
-
(2015)
Drug Metab. Rev
, vol.47
, pp. 111-123
-
-
Colic, A.1
Alessandrini, M.2
Pepper, M.S.3
-
14
-
-
33748163469
-
Are plasma levels valid surrogates for cellular concentrations of antiretroviral drugs in HIV-infected patients?
-
Colombo, S., Telenti, A., Buclin, T., Furrer, H., Lee, B. L., Biollaz, J., et al. (2006). Are plasma levels valid surrogates for cellular concentrations of antiretroviral drugs in HIV-infected patients? Ther. Drug Monit. 28, 332-338. doi: 10.1097/01.ftd.0000211807.74192.62.
-
(2006)
Ther. Drug Monit
, vol.28
, pp. 332-338
-
-
Colombo, S.1
Telenti, A.2
Buclin, T.3
Furrer, H.4
Lee, B.L.5
Biollaz, J.6
-
15
-
-
84872843667
-
Correlates of efavirenz exposure in Chilean patients affected with human immunodeficiency virus reveals a novel association with a polymorphism in the constitutive androstane receptor
-
Cortes, C. P., Siccardi, M., Chaikan, A., Owen, A., Zhang, G., and La Porte, C. J. (2013). Correlates of efavirenz exposure in Chilean patients affected with human immunodeficiency virus reveals a novel association with a polymorphism in the constitutive androstane receptor. Ther. Drug Monit. 35, 78-83. doi: 10.1097/FTD.0b013e318274197e.
-
(2013)
Ther. Drug Monit
, vol.35
, pp. 78-83
-
-
Cortes, C.P.1
Siccardi, M.2
Chaikan, A.3
Owen, A.4
Zhang, G.5
La Porte, C.J.6
-
16
-
-
84938885862
-
CYP2B6*6, CYP2B6*18, Body weight and sex are predictors of efavirenz pharmacokinetics and treatment response: population pharmacokinetic modeling in an HIV/AIDS and TB cohort in Zimbabwe
-
Dhoro, M., Zvada, S., Ngara, B., Nhachi, C., Kadzirange, G., Chonzi, P., et al. (2015). CYP2B6*6, CYP2B6*18, Body weight and sex are predictors of efavirenz pharmacokinetics and treatment response: population pharmacokinetic modeling in an HIV/AIDS and TB cohort in Zimbabwe. BMC Pharmacol. Toxicol. 16:4. doi: 10.1186/s40360-015-0004-2.
-
(2015)
BMC Pharmacol. Toxicol
, vol.16
, pp. 4
-
-
Dhoro, M.1
Zvada, S.2
Ngara, B.3
Nhachi, C.4
Kadzirange, G.5
Chonzi, P.6
-
17
-
-
84952787102
-
Pharmacokinetic and pharmacodynamic comparison of once-daily efavirenz (400 mg vs. 600 mg) in treatment-Naive HIV-infected patients: results of the ENCORE1 study
-
Dickinson, L., Amin, J., Else, L., Boffito, M., Egan, D., Owen, A., et al. (2015). Pharmacokinetic and pharmacodynamic comparison of once-daily efavirenz (400 mg vs. 600 mg) in treatment-Naive HIV-infected patients: results of the ENCORE1 study. Clin. Pharmacol. Ther. 98, 406-416. doi: 10.1002/cpt.156.
-
(2015)
Clin. Pharmacol. Ther
, vol.98
, pp. 406-416
-
-
Dickinson, L.1
Amin, J.2
Else, L.3
Boffito, M.4
Egan, D.5
Owen, A.6
-
18
-
-
63849240305
-
In vivo analysis of efavirenz metabolism in individuals with impaired CYP2A6 function
-
di Iulio, J., Fayet, A., Arab-Alameddine, M., Rotger, M., Lubomirov, R., Cavassini, M., et al. (2009). In vivo analysis of efavirenz metabolism in individuals with impaired CYP2A6 function. Pharmacogenet. Genomics 19, 300-309. doi: 10.1097/FPC.0b013e328328d577.
-
(2009)
Pharmacogenet. Genomics
, vol.19
, pp. 300-309
-
-
di Iulio, J.1
Fayet, A.2
Arab-Alameddine, M.3
Rotger, M.4
Lubomirov, R.5
Cavassini, M.6
-
19
-
-
77957145661
-
Influence of host genetic factors on efavirenz plasma and intracellular pharmacokinetics in HIV-1-infected patients
-
Elens, L., Vandercam, B., Yombi, J. C., Lison, D., Wallemacq, P., and Haufroid, V. (2010). Influence of host genetic factors on efavirenz plasma and intracellular pharmacokinetics in HIV-1-infected patients. Pharmacogenomics 11, 1223-1234. doi: 10.2217/pgs.10.94.
-
(2010)
Pharmacogenomics
, vol.11
, pp. 1223-1234
-
-
Elens, L.1
Vandercam, B.2
Yombi, J.C.3
Lison, D.4
Wallemacq, P.5
Haufroid, V.6
-
20
-
-
84930580439
-
A global health diagnostic for personalized medicine in resource-constrained world settings: a simple PCR-RFLP method for genotyping CYP2B6 g.15582C>T and science and policy relevance for optimal use of antiretroviral drug efavirenz
-
Evans, J., Swart, M., Soko, N., Wonkam, A., Huzair, F., and Dandara, C. (2015). A global health diagnostic for personalized medicine in resource-constrained world settings: a simple PCR-RFLP method for genotyping CYP2B6 g.15582C>T and science and policy relevance for optimal use of antiretroviral drug efavirenz. OMICS 19, 332-338. doi: 10.1089/omi.2015.0039.
-
(2015)
OMICS
, vol.19
, pp. 332-338
-
-
Evans, J.1
Swart, M.2
Soko, N.3
Wonkam, A.4
Huzair, F.5
Dandara, C.6
-
21
-
-
0036499964
-
Quality of life, emotional status, and adherence of HIV-1-infected patients treated with efavirenz versus protease inhibitor-containing regimens
-
Fumaz, C. R., Tuldra, A., Ferrer, M. J., Paredes, R., Bonjoch, A., Jou, T., et al. (2002). Quality of life, emotional status, and adherence of HIV-1-infected patients treated with efavirenz versus protease inhibitor-containing regimens. J. Acquir. Immune Defic. Syndr. 29, 244-253. doi: 10.1097/00042560-200203010-00004.
-
(2002)
J. Acquir. Immune Defic. Syndr
, vol.29
, pp. 244-253
-
-
Fumaz, C.R.1
Tuldra, A.2
Ferrer, M.J.3
Paredes, R.4
Bonjoch, A.5
Jou, T.6
-
22
-
-
35348923463
-
Successful efavirenz dose reduction in HIV type 1-infected individuals with cytochrome P450 2B6 *6 and *26
-
Gatanaga, H., Hayashida, T., Tsuchiya, K., Yoshino, M., Kuwahara, T., Tsukada, H., et al. (2007). Successful efavirenz dose reduction in HIV type 1-infected individuals with cytochrome P450 2B6 *6 and *26. Clin. Infect. Dis. 45, 1230-1237. doi: 10.1086/522175.
-
(2007)
Clin. Infect. Dis
, vol.45
, pp. 1230-1237
-
-
Gatanaga, H.1
Hayashida, T.2
Tsuchiya, K.3
Yoshino, M.4
Kuwahara, T.5
Tsukada, H.6
-
23
-
-
77955694290
-
Presence of the CYP2B6 516G> T polymorphism, increased plasma Efavirenz concentrations and early neuropsychiatric side effects in South African HIV-infected patients
-
Gounden, V., van Niekerk, C., Snyman, T., and George, J. A. (2010). Presence of the CYP2B6 516G> T polymorphism, increased plasma Efavirenz concentrations and early neuropsychiatric side effects in South African HIV-infected patients. AIDS Res. Ther. 7:32. doi: 10.1186/1742-6405-7-32.
-
(2010)
AIDS Res. Ther
, vol.7
, pp. 32
-
-
Gounden, V.1
van Niekerk, C.2
Snyman, T.3
George, J.A.4
-
24
-
-
58149145318
-
Slow efavirenz metabolism genotype is common in Botswana
-
Gross, R., Aplenc, R., Tenhave, T., Foulkes, A. S., Thakur, R., Mosepele, M., et al. (2008). Slow efavirenz metabolism genotype is common in Botswana. J. Acquir. Immune Defic. Syndr. 49, 336-337. doi: 10.1097/QAI.0b013e31817c1ed0.
-
(2008)
J. Acquir. Immune Defic. Syndr
, vol.49
, pp. 336-337
-
-
Gross, R.1
Aplenc, R.2
Tenhave, T.3
Foulkes, A.S.4
Thakur, R.5
Mosepele, M.6
-
25
-
-
0037819284
-
Pharmacogenomics of human UDP-glucuronosyltransferase enzymes
-
Guillemette, C. (2003). Pharmacogenomics of human UDP-glucuronosyltransferase enzymes. Pharmacogenomics J. 3, 136-158. doi: 10.1038/sj.tpj.6500171.
-
(2003)
Pharmacogenomics J
, vol.3
, pp. 136-158
-
-
Guillemette, C.1
-
26
-
-
33747102040
-
Three-vs four-drug antiretroviral regimens for the initial treatment of HIV-1 infection: a randomized controlled trial
-
Gulick, R. M., Ribaudo, H. J., Shikuma, C. M., Lalama, C., Schackman, B. R., Meyer, W. A., et al. (2006). Three-vs four-drug antiretroviral regimens for the initial treatment of HIV-1 infection: a randomized controlled trial. JAMA 296, 769-781. doi: 10.1001/jama.296.7.769.
-
(2006)
JAMA
, vol.296
, pp. 769-781
-
-
Gulick, R.M.1
Ribaudo, H.J.2
Shikuma, C.M.3
Lalama, C.4
Schackman, B.R.5
Meyer, W.A.6
-
27
-
-
32944468048
-
Will pharmacogenomic discoveries improve HIV therapeutics?
-
Haas, D. W. (2005). Will pharmacogenomic discoveries improve HIV therapeutics? Top. HIV Med. 13, 90-95.
-
(2005)
Top. HIV Med
, vol.13
, pp. 90-95
-
-
Haas, D.W.1
-
28
-
-
65649091303
-
Associations between CYP2B6 polymorphisms and pharmacokinetics after a single dose of nevirapine or efavirenz in African americans
-
Haas, D. W., Gebretsadik, T., Mayo, G., Menon, U. N., Acosta, E. P., Shintani, A., et al. (2009). Associations between CYP2B6 polymorphisms and pharmacokinetics after a single dose of nevirapine or efavirenz in African americans. J. Infect. Dis. 199, 872-880. doi: 10.1086/597125.
-
(2009)
J. Infect. Dis
, vol.199
, pp. 872-880
-
-
Haas, D.W.1
Gebretsadik, T.2
Mayo, G.3
Menon, U.N.4
Acosta, E.P.5
Shintani, A.6
-
29
-
-
84904581820
-
Secondary metabolism pathway polymorphisms and plasma efavirenz concentrations in HIV-infected adults with CYP2B6 slow metabolizer genotypes
-
Haas, D. W., Kwara, A., Richardson, D. M., Baker, P., Papageorgiou, I., Acosta, E. P., et al. (2014a). Secondary metabolism pathway polymorphisms and plasma efavirenz concentrations in HIV-infected adults with CYP2B6 slow metabolizer genotypes. J. Antimicrob. Chemother. 69, 2175-2182. doi: 10.1093/jac/dku110.
-
(2014)
J. Antimicrob. Chemother
, vol.69
, pp. 2175-2182
-
-
Haas, D.W.1
Kwara, A.2
Richardson, D.M.3
Baker, P.4
Papageorgiou, I.5
Acosta, E.P.6
-
30
-
-
19944428456
-
Pharmacogenetics of efavirenz and central nervous system side effects: an adult AIDS clinical trials group study
-
Haas, D. W., Ribaudo, H. J., Kim, R. B., Tierney, C., Wilkinson, G. R., Gulick, R. M., et al. (2004). Pharmacogenetics of efavirenz and central nervous system side effects: an adult AIDS clinical trials group study. AIDS 18, 2391-2400.
-
(2004)
AIDS
, vol.18
, pp. 2391-2400
-
-
Haas, D.W.1
Ribaudo, H.J.2
Kim, R.B.3
Tierney, C.4
Wilkinson, G.R.5
Gulick, R.M.6
-
31
-
-
84904561614
-
Functional CYP2B6 variants and virologic response to an efavirenz-containing regimen in Port-au-Prince, Haiti
-
Haas, D. W., Severe, P., Jean Juste, M. A., Pape, J. W., and Fitzgerald, D. W. (2014b). Functional CYP2B6 variants and virologic response to an efavirenz-containing regimen in Port-au-Prince, Haiti. J. Antimicrob. Chemother. 69, 2187-2190. doi: 10.1093/jac/dku088.
-
(2014)
J. Antimicrob. Chemother
, vol.69
, pp. 2187-2190
-
-
Haas, D.W.1
Severe, P.2
Jean Juste, M.A.3
Pape, J.W.4
Fitzgerald, D.W.5
-
32
-
-
27944460707
-
Pharmacogenetics of long-term responses to antiretroviral regimens containing Efavirenz and/or Nelfinavir: an Adult Aids Clinical Trials Group Study
-
Haas, D. W., Smeaton, L. M., Shafer, R. W., Robbins, G. K., Morse, G. D., Labbe, L., et al. (2005). Pharmacogenetics of long-term responses to antiretroviral regimens containing Efavirenz and/or Nelfinavir: an Adult Aids Clinical Trials Group Study. J. Infect. Dis. 192, 1931-1942. doi: 10.1086/497610.
-
(2005)
J. Infect. Dis
, vol.192
, pp. 1931-1942
-
-
Haas, D.W.1
Smeaton, L.M.2
Shafer, R.W.3
Robbins, G.K.4
Morse, G.D.5
Labbe, L.6
-
33
-
-
27744483263
-
Comparison of neuropsychiatric side effects in an observational cohort of efavirenz-and protease inhibitor-treated patients
-
Hawkins, T., Geist, C., Young, B., Giblin, A., Mercier, R. C., Thornton, K., et al. (2005). Comparison of neuropsychiatric side effects in an observational cohort of efavirenz-and protease inhibitor-treated patients. HIV Clin. Trials 6, 187-196. doi: 10.1310/92VR-FP24-J8GA-B49Q.
-
(2005)
HIV Clin. Trials
, vol.6
, pp. 187-196
-
-
Hawkins, T.1
Geist, C.2
Young, B.3
Giblin, A.4
Mercier, R.C.5
Thornton, K.6
-
34
-
-
40849083767
-
A human immunodeficiency virus protease inhibitor is a novel functional inhibitor of human pregnane X receptor
-
Healan-Greenberg, C., Waring, J. F., Kempf, D. J., Blomme, E. A., Tirona, R. G., and Kim, R. B. (2008). A human immunodeficiency virus protease inhibitor is a novel functional inhibitor of human pregnane X receptor. Drug Metab. Dispos. 36, 500-507. doi: 10.1124/dmd.107.019547.
-
(2008)
Drug Metab. Dispos
, vol.36
, pp. 500-507
-
-
Healan-Greenberg, C.1
Waring, J.F.2
Kempf, D.J.3
Blomme, E.A.4
Tirona, R.G.5
Kim, R.B.6
-
35
-
-
84870335137
-
Genome-wide association study of plasma efavirenz pharmacokinetics in AIDS Clinical Trials Group protocols implicates several CYP2B6 variants
-
Holzinger, E. R., Grady, B., Ritchie, M. D., Ribaudo, H. J., Acosta, E. P., Morse, G. D., et al. (2012). Genome-wide association study of plasma efavirenz pharmacokinetics in AIDS Clinical Trials Group protocols implicates several CYP2B6 variants. Pharmacogenet. Genomics. 22, 858-867. doi: 10.1097/FPC.0b013e32835a450b.
-
(2012)
Pharmacogenet. Genomics
, vol.22
, pp. 858-867
-
-
Holzinger, E.R.1
Grady, B.2
Ritchie, M.D.3
Ribaudo, H.J.4
Acosta, E.P.5
Morse, G.D.6
-
36
-
-
80054025177
-
Analysis of pharmacogenetic traits in two distinct South African populations
-
Ikediobi, O., Aouizerat, B., Xiao, Y., Gandhi, M., Gebhardt, S., and Warnich, L. (2011). Analysis of pharmacogenetic traits in two distinct South African populations. Hum. Genomics 5, 265-282. doi: 10.1186/1479-7364-5-4-265.
-
(2011)
Hum. Genomics
, vol.5
, pp. 265-282
-
-
Ikediobi, O.1
Aouizerat, B.2
Xiao, Y.3
Gandhi, M.4
Gebhardt, S.5
Warnich, L.6
-
37
-
-
78149477745
-
Tribal ethnicity and CYP2B6 genetics in Ugandan and Zimbabwean populations in the UK: implications for efavirenz dosing in HIV infection
-
Jamshidi, Y., Moreton, M., McKeown, D. A., Andrews, S., Nithiyananthan, T., Tinworth, L., et al. (2010). Tribal ethnicity and CYP2B6 genetics in Ugandan and Zimbabwean populations in the UK: implications for efavirenz dosing in HIV infection. J. Antimicrob. Chemother. 65, 2614-2619. doi: 10.1093/jac/dkq369.
-
(2010)
J. Antimicrob. Chemother
, vol.65
, pp. 2614-2619
-
-
Jamshidi, Y.1
Moreton, M.2
McKeown, D.A.3
Andrews, S.4
Nithiyananthan, T.5
Tinworth, L.6
-
38
-
-
84555203868
-
A systematic review of the psychiatric side-effects of efavirenz
-
Kenedi, C. A., and Goforth, H. W. (2011). A systematic review of the psychiatric side-effects of efavirenz. AIDS Behav. 15, 1803-1818. doi: 10.1007/s10461-011-9939-5.
-
(2011)
AIDS Behav
, vol.15
, pp. 1803-1818
-
-
Kenedi, C.A.1
Goforth, H.W.2
-
39
-
-
84890582219
-
Comprehensive variant screening of the UGT gene family
-
Kim, J. Y., Cheong, H. S., Park, B. L., Kim, L. H., Namgoong, S., Kim, J. O., et al. (2014). Comprehensive variant screening of the UGT gene family. Yonsei Med. J. 55, 232-239. doi: 10.3349/ymj.2014.55.1.232.
-
(2014)
Yonsei Med. J
, vol.55
, pp. 232-239
-
-
Kim, J.Y.1
Cheong, H.S.2
Park, B.L.3
Kim, L.H.4
Namgoong, S.5
Kim, J.O.6
-
40
-
-
27944492382
-
Genetic variability of CYP2B6 in populations of African and Asian origin: allele frequencies, novel functional variants, and possible implications for anti-HIV therapy with efavirenz
-
Klein, K., Lang, T., Saussele, T., Barbosa-Sicard, E., Schunck, W. H., Eichelbaum, M., et al. (2005). Genetic variability of CYP2B6 in populations of African and Asian origin: allele frequencies, novel functional variants, and possible implications for anti-HIV therapy with efavirenz. Pharmacogenet. Genomics 15, 861-873. doi: 10.1097/01213011-200512000-00004.
-
(2005)
Pharmacogenet. Genomics
, vol.15
, pp. 861-873
-
-
Klein, K.1
Lang, T.2
Saussele, T.3
Barbosa-Sicard, E.4
Schunck, W.H.5
Eichelbaum, M.6
-
41
-
-
84893910819
-
Sleep quality in efavirenz-treated Chinese HIV patients-comparing between GT and GG genotype of CYP2B6-516 G/T polymorphisms
-
Lee, S. S., To, K. W., Lee, M. P., Wong, N. S., Chan, D. P., Li, P. C., et al. (2014). Sleep quality in efavirenz-treated Chinese HIV patients-comparing between GT and GG genotype of CYP2B6-516 G/T polymorphisms. Int. J. STD AIDS 25, 193-200. doi: 10.1177/0956462413498581.
-
(2014)
Int. J. STD AIDS
, vol.25
, pp. 193-200
-
-
Lee, S.S.1
To, K.W.2
Lee, M.P.3
Wong, N.S.4
Chan, D.P.5
Li, P.C.6
-
42
-
-
84880291960
-
Discontinuation of efavirenz therapy in HIV patients due to neuropsychiatric adverse effects
-
Leutscher, P. D., Stecher, C., Storgaard, M., and Larsen, C. S. (2013). Discontinuation of efavirenz therapy in HIV patients due to neuropsychiatric adverse effects. Scand. J. Infect. Dis. 45, 645-651. doi: 10.3109/00365548.2013.773067.
-
(2013)
Scand. J. Infect. Dis
, vol.45
, pp. 645-651
-
-
Leutscher, P.D.1
Stecher, C.2
Storgaard, M.3
Larsen, C.S.4
-
43
-
-
84859236749
-
Worldwide variation in human drug-metabolism enzyme genes CYP2B6 and UGT2B7: implications for HIV/AIDS treatment
-
Li, J., Menard, V., Benish, R. L., Jurevic, R. J., Guillemette, C., Stoneking, M., et al. (2012). Worldwide variation in human drug-metabolism enzyme genes CYP2B6 and UGT2B7: implications for HIV/AIDS treatment. Pharmacogenomics 13, 555-570. doi: 10.2217/pgs.11.160.
-
(2012)
Pharmacogenomics
, vol.13
, pp. 555-570
-
-
Li, J.1
Menard, V.2
Benish, R.L.3
Jurevic, R.J.4
Guillemette, C.5
Stoneking, M.6
-
44
-
-
64149129845
-
A partition-ligation-combination-subdivision EM algorithm for haplotype inference with multiallelic markers: update of the SHEsis
-
Li, Z., Zhang, Z., He, Z., Tang, W., Li, T., Zeng, Z., et al. (2009). A partition-ligation-combination-subdivision EM algorithm for haplotype inference with multiallelic markers: update of the SHEsis (http://analysis.bio-x.cn). Cell Res. 19, 519-523. doi: 10.1038/cr.2009.33.
-
(2009)
Cell Res
, vol.19
, pp. 519-523
-
-
Li, Z.1
Zhang, Z.2
He, Z.3
Tang, W.4
Li, T.5
Zeng, Z.6
-
45
-
-
79851482408
-
Association of pharmacogenetic markers with premature discontinuation of first-line anti-HIV therapy: an observational cohort study
-
Lubomirov, R., Colombo, S., di Iulio, J., Ledergerber, B., Martinez, R., Cavassini, M., et al. (2011). Association of pharmacogenetic markers with premature discontinuation of first-line anti-HIV therapy: an observational cohort study. J. Infect. Dis. 203, 246-257. doi: 10.1093/infdis/jiq043.
-
(2011)
J. Infect. Dis
, vol.203
, pp. 246-257
-
-
Lubomirov, R.1
Colombo, S.2
di Iulio, J.3
Ledergerber, B.4
Martinez, R.5
Cavassini, M.6
-
46
-
-
84857062673
-
CYP2B6 genotype is a strong predictor of systemic exposure to efavirenz in HIV-infected Zimbabweans
-
Maimbo, M., Kiyotani, K., Mushiroda, T., Masimirembwa, C., and Nakamura, Y. (2012). CYP2B6 genotype is a strong predictor of systemic exposure to efavirenz in HIV-infected Zimbabweans. Eur. J. Clin. Pharmacol. 68, 267-271. doi: 10.1007/s00228-011-1118-0.
-
(2012)
Eur. J. Clin. Pharmacol
, vol.68
, pp. 267-271
-
-
Maimbo, M.1
Kiyotani, K.2
Mushiroda, T.3
Masimirembwa, C.4
Nakamura, Y.5
-
47
-
-
0035875828
-
Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients
-
Marzolini, C., Telenti, A., Decosterd, L. A., Greub, G., Biollaz, J., and Buclin, T. (2001). Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients. AIDS 15, 71-75. doi: 10.1097/00002030-200101050-00011.
-
(2001)
AIDS
, vol.15
, pp. 71-75
-
-
Marzolini, C.1
Telenti, A.2
Decosterd, L.A.3
Greub, G.4
Biollaz, J.5
Buclin, T.6
-
48
-
-
34548033928
-
CYP2B6 983T>C polymorphism is prevalent in West Africa but absent in Papua New Guinea: implications for HIV/AIDS treatment
-
Mehlotra, R. K., Bockarie, M. J., and Zimmerman, P. A. (2007). CYP2B6 983T>C polymorphism is prevalent in West Africa but absent in Papua New Guinea: implications for HIV/AIDS treatment. Br. J. Clin. Pharmacol. 64, 391-395. doi: 10.1111/j.1365-2125.2007.02884.x.
-
(2007)
Br. J. Clin. Pharmacol
, vol.64
, pp. 391-395
-
-
Mehlotra, R.K.1
Bockarie, M.J.2
Zimmerman, P.A.3
-
49
-
-
33645683551
-
Prevalence of CYP2B6 alleles in malaria-endemic populations of West Africa and Papua New Guinea
-
Mehlotra, R. K., Ziats, M. N., Bockarie, M. J., and Zimmerman, P. A. (2006). Prevalence of CYP2B6 alleles in malaria-endemic populations of West Africa and Papua New Guinea. Eur. J. Clin. Pharmacol. 62, 267-275. doi: 10.1007/s00228-005-0092-9.
-
(2006)
Eur. J. Clin. Pharmacol
, vol.62
, pp. 267-275
-
-
Mehlotra, R.K.1
Ziats, M.N.2
Bockarie, M.J.3
Zimmerman, P.A.4
-
50
-
-
0032585914
-
Efavirenz: practicalities, considerations and new issues
-
Moyle, G. (1999a). Efavirenz: practicalities, considerations and new issues. Int. J. Clin. Pract. Suppl. 103, 30-34.
-
(1999)
Int. J. Clin. Pract. Suppl
, vol.103
, pp. 30-34
-
-
Moyle, G.1
-
51
-
-
0032960877
-
Efavirenz: shifting the HAART paradigm in adult HIV-1 infection
-
Moyle, G. J. (1999b). Efavirenz: shifting the HAART paradigm in adult HIV-1 infection. Expert Opin. Investig. Drugs 8, 473-486.
-
(1999)
Expert Opin. Investig. Drugs
, vol.8
, pp. 473-486
-
-
Moyle, G.J.1
-
52
-
-
84878378977
-
Influence of efavirenz pharmacokinetics and pharmacogenetics on neuropsychological disorders in Ugandan HIV-positive patients with or without tuberculosis: a prospective cohort study
-
Mukonzo, J. K., Okwera, A., Nakasujja, N., Luzze, H., Sebuwufu, D., Ogwal-Okeng, J., et al. (2013). Influence of efavirenz pharmacokinetics and pharmacogenetics on neuropsychological disorders in Ugandan HIV-positive patients with or without tuberculosis: a prospective cohort study. BMC Infect. Dis. 13:261. doi: 10.1186/1471-2334-13-261.
-
(2013)
BMC Infect. Dis
, vol.13
, pp. 261
-
-
Mukonzo, J.K.1
Okwera, A.2
Nakasujja, N.3
Luzze, H.4
Sebuwufu, D.5
Ogwal-Okeng, J.6
-
53
-
-
84900337388
-
Pharmacogenetic-based efavirenz dose modification: suggestions for an African population and the different CYP2B6 genotypes
-
Mukonzo, J. K., Owen, J. S., Ogwal-Okeng, J., Kuteesa, R. B., Nanzigu, S., Sewankambo, N., et al. (2014). Pharmacogenetic-based efavirenz dose modification: suggestions for an African population and the different CYP2B6 genotypes. PLoS ONE 9:e86919. doi: 10.1371/journal.pone.0086919.
-
(2014)
PLoS ONE
, vol.9
-
-
Mukonzo, J.K.1
Owen, J.S.2
Ogwal-Okeng, J.3
Kuteesa, R.B.4
Nanzigu, S.5
Sewankambo, N.6
-
54
-
-
70449334327
-
A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans
-
Mukonzo, J. K., Röshammar, D., Waako, P., Andersson, M., Fukasawa, T., Milani, L., et al. (2009). A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans. Br. J. Clin. Pharmacol. 68, 690-699. doi: 10.1111/j.1365-2125.2009.03516.x.
-
(2009)
Br. J. Clin. Pharmacol
, vol.68
, pp. 690-699
-
-
Mukonzo, J.K.1
Röshammar, D.2
Waako, P.3
Andersson, M.4
Fukasawa, T.5
Milani, L.6
-
55
-
-
84896491775
-
Impact of CYP polymorphisms, ethnicity and sex differences in metabolism on dosing strategies: the case of efavirenz
-
Naidoo, P., Chetty, V. V., and Chetty, M. (2014). Impact of CYP polymorphisms, ethnicity and sex differences in metabolism on dosing strategies: the case of efavirenz. Eur. J. Clin. Pharmacol. 70, 379-389. doi: 10.1007/s00228-013-1634-1.
-
(2014)
Eur. J. Clin. Pharmacol
, vol.70
, pp. 379-389
-
-
Naidoo, P.1
Chetty, V.V.2
Chetty, M.3
-
56
-
-
84879813185
-
Importance of ethnicity, CYP2B6 and ABCB1 genotype for efavirenz pharmacokinetics and treatment outcomes: a parallel-group prospective cohort study in two sub-Saharan Africa populations
-
Ngaimisi, E., Habtewold, A., Minzi, O., Makonnen, E., Mugusi, S., Amogne, W., et al. (2013). Importance of ethnicity, CYP2B6 and ABCB1 genotype for efavirenz pharmacokinetics and treatment outcomes: a parallel-group prospective cohort study in two sub-Saharan Africa populations. PLoS ONE 8:e67946. doi: 10.1371/journal.pone.0067946.
-
(2013)
PLoS ONE
, vol.8
-
-
Ngaimisi, E.1
Habtewold, A.2
Minzi, O.3
Makonnen, E.4
Mugusi, S.5
Amogne, W.6
-
57
-
-
31044453437
-
Efavirenz and CYP2B6 polymorphism: implications for drug toxicity and resistance
-
Nolan, D., Phillips, E., and Mallal, S. (2006). Efavirenz and CYP2B6 polymorphism: implications for drug toxicity and resistance. Clin. Infect. Dis. 42, 408-410. doi: 10.1086/499369.
-
(2006)
Clin. Infect. Dis
, vol.42
, pp. 408-410
-
-
Nolan, D.1
Phillips, E.2
Mallal, S.3
-
58
-
-
40049092364
-
High prevalence of the CYP2B6 516G->T(*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe
-
Nyakutira, C., Röshammar, D., Chigutsa, E., Chonzi, P., Ashton, M., Nhachi, C., et al. (2008). High prevalence of the CYP2B6 516G->T(*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe. Eur. J. Clin. Pharmacol. 64, 357-365. doi: 10.1007/s00228-007-0412-3.
-
(2008)
Eur. J. Clin. Pharmacol
, vol.64
, pp. 357-365
-
-
Nyakutira, C.1
Röshammar, D.2
Chigutsa, E.3
Chonzi, P.4
Ashton, M.5
Nhachi, C.6
-
59
-
-
77953756056
-
Efavirenz primary and secondary metabolism in vitro and in vivo: identification of novel metabolic pathways and cytochrome P450 2A6 as the principal catalyst of efavirenz 7-hydroxylation
-
Ogburn, E. T., Jones, D. R., Masters, A. R., Xu, C., Guo, Y., and Desta, Z. (2010). Efavirenz primary and secondary metabolism in vitro and in vivo: identification of novel metabolic pathways and cytochrome P450 2A6 as the principal catalyst of efavirenz 7-hydroxylation. Drug Metab. Dispos. 38, 1218-1229. doi: 10.1124/dmd.109.031393.
-
(2010)
Drug Metab. Dispos
, vol.38
, pp. 1218-1229
-
-
Ogburn, E.T.1
Jones, D.R.2
Masters, A.R.3
Xu, C.4
Guo, Y.5
Desta, Z.6
-
60
-
-
67649517091
-
A pharmacogenetic study of CD4 recovery in response to HIV antiretroviral therapy in two South African population groups
-
Parathyras, J., Gebhardt, S., Hillermann-Rebello, R., Grobbelaar, N., Venter, M., and Warnich, L. (2009). A pharmacogenetic study of CD4 recovery in response to HIV antiretroviral therapy in two South African population groups. J. Hum. Genet. 54, 261-265. doi: 10.1038/jhg.2009.20.
-
(2009)
J. Hum. Genet
, vol.54
, pp. 261-265
-
-
Parathyras, J.1
Gebhardt, S.2
Hillermann-Rebello, R.3
Grobbelaar, N.4
Venter, M.5
Warnich, L.6
-
61
-
-
33847793822
-
Cytochrome P450 2B6 (CYP2B6) G516T influences nevirapine plasma concentrations in HIV-infected patients in Uganda
-
Penzak, S. R., Kabuye, G., Mugyenyi, P., Mbamanya, F., Natarajan, V., Alfaro, R. M., et al. (2007). Cytochrome P450 2B6 (CYP2B6) G516T influences nevirapine plasma concentrations in HIV-infected patients in Uganda. HIV Med. 8, 86-91. doi: 10.1111/j.1468-1293.2007.00432.x.
-
(2007)
HIV Med
, vol.8
, pp. 86-91
-
-
Penzak, S.R.1
Kabuye, G.2
Mugyenyi, P.3
Mbamanya, F.4
Natarajan, V.5
Alfaro, R.M.6
-
62
-
-
80054702221
-
Plasma concentrations of efavirenz are associated with body weight in HIV-positive individuals
-
Poeta, J., Linden, R., Antunes, M. V., Real, L., Menezes, A. M., Ribeiro, J. P., et al. (2011). Plasma concentrations of efavirenz are associated with body weight in HIV-positive individuals. J. Antimicrob. Chemother. 66, 2601-2604. doi: 10.1093/jac/dkr360.
-
(2011)
J. Antimicrob. Chemother
, vol.66
, pp. 2601-2604
-
-
Poeta, J.1
Linden, R.2
Antunes, M.V.3
Real, L.4
Menezes, A.M.5
Ribeiro, J.P.6
-
63
-
-
84902516981
-
Has the time come to abandon efavirenz for first-line antiretroviral therapy?
-
Raffi, F., Pozniak, A. L., and Wainberg, M. A. (2014). Has the time come to abandon efavirenz for first-line antiretroviral therapy? J. Antimicrob. Chemother. 69, 1742-1747. doi: 10.1093/jac/dku058.
-
(2014)
J. Antimicrob. Chemother
, vol.69
, pp. 1742-1747
-
-
Raffi, F.1
Pozniak, A.L.2
Wainberg, M.A.3
-
64
-
-
34548552964
-
Pharmacogenetics of antiretroviral therapy
-
Rotger, M., Lubomirov, R., Rodriguez-Novoa, S., and Barreiro, P. (2006). [Pharmacogenetics of antiretroviral therapy.]. Enferm. Infecc. Microbiol. Clin. 24(Suppl. 2), 13-18. doi: 10.1157/13096045.
-
(2006)
Enferm. Infecc. Microbiol. Clin
, vol.24
, pp. 13-18
-
-
Rotger, M.1
Lubomirov, R.2
Rodriguez-Novoa, S.3
Barreiro, P.4
-
65
-
-
33947382259
-
Predictive value of known and novel alleles of CYP2B6 for efavirenz plasma concentrations in HIV-infected individuals
-
Rotger, M., Tegude, H., Colombo, S., Cavassini, M., Furrer, H., Décosterd, L., et al. (2007). Predictive value of known and novel alleles of CYP2B6 for efavirenz plasma concentrations in HIV-infected individuals. Clin. Pharmacol. Ther. 81, 557-566. doi: 10.1038/sj.clpt.6100072.
-
(2007)
Clin. Pharmacol. Ther
, vol.81
, pp. 557-566
-
-
Rotger, M.1
Tegude, H.2
Colombo, S.3
Cavassini, M.4
Furrer, H.5
Décosterd, L.6
-
66
-
-
40049094339
-
Optimizing efavirenz treatment: CYP2B6 genotyping or therapeutic drug monitoring?
-
Rotger, M., and Telenti, A. (2008). Optimizing efavirenz treatment: CYP2B6 genotyping or therapeutic drug monitoring? Eur. J. Clin. Pharmacol. 64, 335-336. doi: 10.1007/s00228-007-0440-z.
-
(2008)
Eur. J. Clin. Pharmacol
, vol.64
, pp. 335-336
-
-
Rotger, M.1
Telenti, A.2
-
67
-
-
84880456997
-
Impact of pharmacogenetics on CNS side effects related to efavirenz
-
Sanchez Martin, A., Cabrera Figueroa, S., Cruz Guerrero, R., Hurtado, L. P., Hurle, A. D., and Carracedo Alvarez, A. (2013). Impact of pharmacogenetics on CNS side effects related to efavirenz. Pharmacogenomics 14, 1167-1178. doi: 10.2217/pgs.13.111.
-
(2013)
Pharmacogenomics
, vol.14
, pp. 1167-1178
-
-
Sanchez Martin, A.1
Cabrera Figueroa, S.2
Cruz Guerrero, R.3
Hurtado, L.P.4
Hurle, A.D.5
Carracedo Alvarez, A.6
-
68
-
-
84892471332
-
Pharmacogenetic associations with plasma efavirenz concentrations and clinical correlates in a retrospective cohort of Ghanaian HIV-infected patients
-
Sarfo, F. S., Zhang, Y., Egan, D., Tetteh, L. A., Phillips, R., Bedu-Addo, G., et al. (2013). Pharmacogenetic associations with plasma efavirenz concentrations and clinical correlates in a retrospective cohort of Ghanaian HIV-infected patients. J. Antimicrob. Chemother. 69, 491-499. doi: 10.1093/jac/dkt372.
-
(2013)
J. Antimicrob. Chemother
, vol.69
, pp. 491-499
-
-
Sarfo, F.S.1
Zhang, Y.2
Egan, D.3
Tetteh, L.A.4
Phillips, R.5
Bedu-Addo, G.6
-
69
-
-
84892471332
-
Pharmacogenetic associations with plasma efavirenz concentrations and clinical correlates in a retrospective cohort of Ghanaian HIV-infected patients
-
Sarfo, F. S., Zhang, Y., Egan, D., Tetteh, L. A., Phillips, R., Bedu-Addo, G., et al. (2014). Pharmacogenetic associations with plasma efavirenz concentrations and clinical correlates in a retrospective cohort of Ghanaian HIV-infected patients. J. Antimicrob. Chemother. 69, 491-499. doi: 10.1093/jac/dkt372.
-
(2014)
J. Antimicrob. Chemother
, vol.69
, pp. 491-499
-
-
Sarfo, F.S.1
Zhang, Y.2
Egan, D.3
Tetteh, L.A.4
Phillips, R.5
Bedu-Addo, G.6
-
70
-
-
84948988283
-
Cost-effectiveness of CYP2B6 genotyping to optimize efavirenz dosing in HIV clinical practice
-
Schackman, B. R., Haas, D. W., Park, S. S., Li, X. C., and Freedberg, K. A. (2015). Cost-effectiveness of CYP2B6 genotyping to optimize efavirenz dosing in HIV clinical practice. Pharmacogenomics 16, 2007-2018. doi: 10.2217/pgs.15.142.
-
(2015)
Pharmacogenomics
, vol.16
, pp. 2007-2018
-
-
Schackman, B.R.1
Haas, D.W.2
Park, S.S.3
Li, X.C.4
Freedberg, K.A.5
-
71
-
-
79956053313
-
Integration of population pharmacokinetics and pharmacogenetics: an aid to optimal nevirapine dose selection in HIV-infected individuals
-
Schipani, A., Wyen, C., Mahungu, T., Hendra, H., Egan, D., Siccardi, M., et al. (2011). Integration of population pharmacokinetics and pharmacogenetics: an aid to optimal nevirapine dose selection in HIV-infected individuals. J. Antimicrob. Chemother. 66, 1332-1339. doi: 10.1093/jac/dkr087.
-
(2011)
J. Antimicrob. Chemother
, vol.66
, pp. 1332-1339
-
-
Schipani, A.1
Wyen, C.2
Mahungu, T.3
Hendra, H.4
Egan, D.5
Siccardi, M.6
-
72
-
-
18944381751
-
SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci
-
Shi, Y. Y., and He, L. (2005). SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci. Cell Res. 15, 97-98. doi: 10.1038/sj.cr.7290272.
-
(2005)
Cell Res
, vol.15
, pp. 97-98
-
-
Shi, Y.Y.1
He, L.2
-
73
-
-
84933040566
-
Pharmacogenetics of plasma efavirenz exposure in HIV-infected adults and children in South Africa
-
Sinxadi, P. Z., Leger, P. D., McIlleron, H. M., Smith, P. J., Dave, J. A., Levitt, N. S., et al. (2015). Pharmacogenetics of plasma efavirenz exposure in HIV-infected adults and children in South Africa. Br. J. Clin. Pharmacol. 80, 146-156. doi: 10.1111/bcp.12590.
-
(2015)
Br. J. Clin. Pharmacol
, vol.80
, pp. 146-156
-
-
Sinxadi, P.Z.1
Leger, P.D.2
McIlleron, H.M.3
Smith, P.J.4
Dave, J.A.5
Levitt, N.S.6
-
74
-
-
2542549644
-
Efavirenz plasma concentrations in HIV-infected patients: inter-and intraindividual variability and clinical effects
-
Ståhle, L., Moberg, L., Svensson, J. O., and Sönnerborg, A. (2004). Efavirenz plasma concentrations in HIV-infected patients: inter-and intraindividual variability and clinical effects. Ther. Drug Monit. 26, 267-270. doi: 10.1097/00007691-200406000-00008.
-
(2004)
Ther. Drug Monit
, vol.26
, pp. 267-270
-
-
Ståhle, L.1
Moberg, L.2
Svensson, J.O.3
Sönnerborg, A.4
-
75
-
-
49949084478
-
Factors influencing efavirenz and nevirapine plasma concentration: effect of ethnicity, weight and co-medication
-
Stöhr, W., Back, D., Dunn, D., Sabin, C., Winston, A., Gilson, R., et al. (2008). Factors influencing efavirenz and nevirapine plasma concentration: effect of ethnicity, weight and co-medication. Antivir. Ther. 13, 675-685.
-
(2008)
Antivir. Ther
, vol.13
, pp. 675-685
-
-
Stöhr, W.1
Back, D.2
Dunn, D.3
Sabin, C.4
Winston, A.5
Gilson, R.6
-
76
-
-
84901648608
-
Low level of efavirenz in HIV-1-infected Thai adults is associated with the CYP2B6 polymorphism
-
Sukasem, C., Manosuthi, W., Koomdee, N., Santon, S., Jantararoungtong, T., Prommas, S., et al. (2014). Low level of efavirenz in HIV-1-infected Thai adults is associated with the CYP2B6 polymorphism. Infection 42, 469-474. doi: 10.1007/s15010-013-0560-6.
-
(2014)
Infection
, vol.42
, pp. 469-474
-
-
Sukasem, C.1
Manosuthi, W.2
Koomdee, N.3
Santon, S.4
Jantararoungtong, T.5
Prommas, S.6
-
77
-
-
84906279761
-
Genetic variation in the 3'-UTR of CYP1A2, CYP2B6, CYP2D6, CYP3A4, NR1I2, and UGT2B7: potential effects on regulation by microRNA and pharmacogenomics relevance
-
Swart, M., and Dandara, C. (2014). Genetic variation in the 3'-UTR of CYP1A2, CYP2B6, CYP2D6, CYP3A4, NR1I2, and UGT2B7: potential effects on regulation by microRNA and pharmacogenomics relevance. Front. Genet. 5:167. doi: 10.3389/fgene.2014.00167.
-
(2014)
Front. Genet
, vol.5
, pp. 167
-
-
Swart, M.1
Dandara, C.2
-
78
-
-
84876108975
-
ABCB1 4036A>G and 1236C>T polymorphisms affect plasma efavirenz levels in South African HIV/AIDS patients
-
Swart, M., Ren, Y., Smith, P., and Dandara, C. (2012a). ABCB1 4036A>G and 1236C>T polymorphisms affect plasma efavirenz levels in South African HIV/AIDS patients. Front. Genet. 3:236. doi: 10.3389/fgene.2012.00236.
-
(2012)
Front. Genet
, vol.3
, pp. 236
-
-
Swart, M.1
Ren, Y.2
Smith, P.3
Dandara, C.4
-
79
-
-
84880922434
-
High predictive value of CYP2B6 SNPs for steady-state plasma efavirenz levels in South African HIV/AIDS patients
-
Swart, M., Skelton, M., Ren, Y., Smith, P., Takuva, S., and Dandara, C. (2013). High predictive value of CYP2B6 SNPs for steady-state plasma efavirenz levels in South African HIV/AIDS patients. Pharmacogenet. Genomics 23, 415-427. doi: 10.1097/FPC.0b013e328363176f.
-
(2013)
Pharmacogenet. Genomics
, vol.23
, pp. 415-427
-
-
Swart, M.1
Skelton, M.2
Ren, Y.3
Smith, P.4
Takuva, S.5
Dandara, C.6
-
80
-
-
84860266612
-
CYP1A2, CYP2A6, CYP2B6, CYP3A4 and CYP3A5 polymorphisms in two bantu-speaking populations from cameroon and South Africa: implications for global pharmacogenetics
-
Swart, M., Skelton, M., Wonkam, A., Kannemeyer, L., Chin'Ombe, N., and Dandara, C. (2012b). CYP1A2, CYP2A6, CYP2B6, CYP3A4 and CYP3A5 polymorphisms in two bantu-speaking populations from cameroon and South Africa: implications for global pharmacogenetics. Curr. Pharmacogenomics Person. Med. 10, 43-53. doi: 10.2174/1875692111201010043.
-
(2012)
Curr. Pharmacogenomics Person. Med
, vol.10
, pp. 43-53
-
-
Swart, M.1
Skelton, M.2
Wonkam, A.3
Kannemeyer, L.4
Chin'Ombe, N.5
Dandara, C.6
-
81
-
-
84869862527
-
PXR and CAR single nucleotide polymorphisms influence plasma efavirenz levels in South African HIV/AIDS patients
-
Swart, M., Whitehorn, H., Ren, Y., Smith, P., Ramesar, R. S., and Dandara, C. (2012c). PXR and CAR single nucleotide polymorphisms influence plasma efavirenz levels in South African HIV/AIDS patients. BMC Med. Genet. 13:112. doi: 10.1186/1471-2350-13-112.
-
(2012)
BMC Med. Genet
, vol.13
, pp. 112
-
-
Swart, M.1
Whitehorn, H.2
Ren, Y.3
Smith, P.4
Ramesar, R.S.5
Dandara, C.6
-
82
-
-
53149086277
-
A pharmacokinetic and pharmacogenetic study of efavirenz in children: dosing guidelines can result in subtherapeutic concentrations
-
ter Heine, R., Scherpbier, H. J., Crommentuyn, K. M., Bekker, V., Beijnen, J. H., Kuijpers, T. W., et al. (2008). A pharmacokinetic and pharmacogenetic study of efavirenz in children: dosing guidelines can result in subtherapeutic concentrations. Antivir. Ther. 13, 779-787.
-
(2008)
Antivir. Ther
, vol.13
, pp. 779-787
-
-
ter Heine, R.1
Scherpbier, H.J.2
Crommentuyn, K.M.3
Bekker, V.4
Beijnen, J.H.5
Kuijpers, T.W.6
-
83
-
-
84862020111
-
UGT2B7 genetic polymorphisms are associated with the withdrawal symptoms in methadone maintenance patients
-
Tian, J. N., Ho, I. K., Tsou, H. H., Fang, C. P., Hsiao, C. F., Chen, C. H., et al. (2012). UGT2B7 genetic polymorphisms are associated with the withdrawal symptoms in methadone maintenance patients. Pharmacogenomics 13, 879-888. doi: 10.2217/pgs.12.69.
-
(2012)
Pharmacogenomics
, vol.13
, pp. 879-888
-
-
Tian, J.N.1
Ho, I.K.2
Tsou, H.H.3
Fang, C.P.4
Hsiao, C.F.5
Chen, C.H.6
-
85
-
-
0038002981
-
The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity
-
Ward, B. A., Gorski, J. C., Jones, D. R., Hall, S. D., Flockhart, D. A., and Desta, Z. (2003). The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity. J. Pharmacol. Exp. Ther. 306, 287-300. doi: 10.1124/jpet.103.049601.
-
(2003)
J. Pharmacol. Exp. Ther
, vol.306
, pp. 287-300
-
-
Ward, B.A.1
Gorski, J.C.2
Jones, D.R.3
Hall, S.D.4
Flockhart, D.A.5
Desta, Z.6
-
86
-
-
33748874526
-
Switch from efavirenz to nevirapine associated with resolution of efavirenz-related neuropsychiatric adverse events and improvement in lipid profiles
-
Ward, D. J., and Curtin, J. M. (2006). Switch from efavirenz to nevirapine associated with resolution of efavirenz-related neuropsychiatric adverse events and improvement in lipid profiles. AIDS Patient Care STDS 20, 542-548. doi: 10.1089/apc.2006.20.542.
-
(2006)
AIDS Patient Care STDS
, vol.20
, pp. 542-548
-
-
Ward, D.J.1
Curtin, J.M.2
-
87
-
-
80051685348
-
Cytochrome P450 2B6 (CYP2B6) and constitutive androstane receptor (CAR) polymorphisms are associated with early discontinuation of efavirenz-containing regimens
-
Wyen, C., Hendra, H., Siccardi, M., Platten, M., Jaeger, H., Harrer, T., et al. (2011). Cytochrome P450 2B6 (CYP2B6) and constitutive androstane receptor (CAR) polymorphisms are associated with early discontinuation of efavirenz-containing regimens. J. Antimicrob. Chemother. 66, 2092-2098. doi: 10.1093/jac/dkr272.
-
(2011)
J. Antimicrob. Chemother
, vol.66
, pp. 2092-2098
-
-
Wyen, C.1
Hendra, H.2
Siccardi, M.3
Platten, M.4
Jaeger, H.5
Harrer, T.6
-
88
-
-
41149092923
-
Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients
-
Wyen, C., Hendra, H., Vogel, M., Hoffmann, C., Knechten, H., Brockmeyer, N. H., et al. (2008). Impact of CYP2B6 983T>C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients. J. Antimicrob. Chemother. 61, 914-918. doi: 10.1093/jac/dkn029.
-
(2008)
J. Antimicrob. Chemother
, vol.61
, pp. 914-918
-
-
Wyen, C.1
Hendra, H.2
Vogel, M.3
Hoffmann, C.4
Knechten, H.5
Brockmeyer, N.H.6
-
89
-
-
55549110397
-
Influence of uridine diphosphate (UDP)-glucuronosyltransferases and ABCC2 genetic polymorphisms on the pharmacokinetics of mycophenolic acid and its metabolites in Chinese renal transplant recipients
-
Zhang, W. X., Chen, B., Jin, Z., Yu, Z., Wang, X., Chen, H., et al. (2008). Influence of uridine diphosphate (UDP)-glucuronosyltransferases and ABCC2 genetic polymorphisms on the pharmacokinetics of mycophenolic acid and its metabolites in Chinese renal transplant recipients. Xenobiotica 38, 1422-1436. doi: 10.1080/00498250802488585.
-
(2008)
Xenobiotica
, vol.38
, pp. 1422-1436
-
-
Zhang, W.X.1
Chen, B.2
Jin, Z.3
Yu, Z.4
Wang, X.5
Chen, H.6
|