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Volumn 16, Issue 18, 2015, Pages 2007-2018

Cost-effectiveness of CYP2B6 genotyping to optimize efavirenz dosing in HIV clinical practice

Author keywords

antiretroviral therapy; cost effectiveness; dose optimization; genotyping; HIV

Indexed keywords

CYTOCHROME P450 2B6; EFAVIRENZ; EFAVIRENZ PLUS EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; GENERIC DRUG; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; BENZOXAZINE DERIVATIVE;

EID: 84948988283     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/pgs.15.142     Document Type: Article
Times cited : (18)

References (52)
  • 2
    • 33747102040 scopus 로고    scopus 로고
    • Three-vs fourdrug antiretroviral regimens for the initial treatment of HIV-1 infection: A randomized controlled trial
    • Gulick RM, Ribaudo HJ, Shikuma CM et al. Three-vs fourdrug antiretroviral regimens for the initial treatment of HIV-1 infection: a randomized controlled trial. JAMA 296(7), 769-781 (2006).
    • (2006) JAMA , vol.296 , Issue.7 , pp. 769-781
    • Gulick, R.M.1    Ribaudo, H.J.2    Shikuma, C.M.3
  • 3
    • 79955440277 scopus 로고    scopus 로고
    • Atazanavir plus ritonavir or efavirenz as part of a 3-drug regimen for initial treatment of HIV-1
    • Daar ES, Tierney C, Fischl MA et al. Atazanavir plus ritonavir or efavirenz as part of a 3-drug regimen for initial treatment of HIV-1. Ann. Intern. Med. 154(7), 445-456 (2011).
    • (2011) Ann. Intern. Med , vol.154 , Issue.7 , pp. 445-456
    • Daar, E.S.1    Tierney, C.2    Fischl, M.A.3
  • 4
    • 19944428456 scopus 로고    scopus 로고
    • Pharmacogenetics of efavirenz and central nervous system side Effects: An Adult AIDS Clinical Trials Group study
    • Haas DW, Ribaudo HJ, Kim RB et al. Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study. AIDS 18(18), 2391-2400 (2004).
    • (2004) AIDS , vol.18 , Issue.18 , pp. 2391-2400
    • Haas, D.W.1    Ribaudo, H.J.2    Kim, R.B.3
  • 5
    • 20244364148 scopus 로고    scopus 로고
    • Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients
    • Rotger M, Colombo S, Furrer H et al. Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients. Pharmacogenet. Genomics 15(1), 1-5 (2005).
    • (2005) Pharmacogenet. Genomics , vol.15 , Issue.1 , pp. 1-5
    • Rotger, M.1    Colombo, S.2    Furrer, H.3
  • 6
    • 27944460707 scopus 로고    scopus 로고
    • Pharmacogenetics of long-term responses to antiretroviral regimens containing efavirenz and/or nelfinavir: An Adult AIDS Clinical Trials Group Study
    • Haas DW, Smeaton LM, Shafer RW et al. Pharmacogenetics of long-term responses to antiretroviral regimens containing efavirenz and/or nelfinavir: an Adult AIDS Clinical Trials Group Study. J. Infect. Dis. 192(11), 1931-1942 (2005).
    • (2005) J. Infect. Dis , vol.192 , Issue.11 , pp. 1931-1942
    • Haas, D.W.1    Smeaton, L.M.2    Shafer, R.W.3
  • 7
    • 84870335137 scopus 로고    scopus 로고
    • Genome-wide association study of plasma efavirenz pharmacokinetics in AIDS Clinical Trials Group protocols implicates several CYP2B6 variants
    • Holzinger ER, Grady B, Ritchie MD et al. Genome-wide association study of plasma efavirenz pharmacokinetics in AIDS Clinical Trials Group protocols implicates several CYP2B6 variants. Pharmacogenet. Genomics 22(12), 858-867 (2012).
    • (2012) Pharmacogenet. Genomics , vol.22 , Issue.12 , pp. 858-867
    • Holzinger, E.R.1    Grady, B.2    Ritchie, M.D.3
  • 8
    • 33644588715 scopus 로고    scopus 로고
    • Identification of a novel specific CYP2B6 allele in Africans causing impaired metabolism of the HIV drug efavirenz
    • Wang J, Sonnerborg A, Rane A et al. Identification of a novel specific CYP2B6 allele in Africans causing impaired metabolism of the HIV drug efavirenz. Pharmacogenet. Genomics 16(3), 191-198 (2006).
    • (2006) Pharmacogenet. Genomics , vol.16 , Issue.3 , pp. 191-198
    • Wang, J.1    Sonnerborg, A.2    Rane, A.3
  • 9
    • 77955685573 scopus 로고    scopus 로고
    • ABCB1, and CYP3A5 polymorphisms on efavirenz pharmacokinetics and treatment response: An AIDS Clinical Trials Group study
    • Effect of CYP2B6
    • Ribaudo HJ, Liu H, Schwab M et al. Effect of CYP2B6, ABCB1, and CYP3A5 polymorphisms on efavirenz pharmacokinetics and treatment response: an AIDS Clinical Trials Group study. J. Infect. Dis. 202(5), 717-722 (2010).
    • (2010) J. Infect. Dis , vol.202 , Issue.5 , pp. 717-722
    • Ribaudo, H.J.1    Liu, H.2    Schwab, M.3
  • 10
    • 35348923463 scopus 로고    scopus 로고
    • Successful efavirenz dose reduction in HIV type 1-infected individuals with cytochrome P450 2B66 and26
    • Gatanaga H, Hayashida T, Tsuchiya K et al. Successful efavirenz dose reduction in HIV type 1-infected individuals with cytochrome P450 2B6∗6 and 26. Clin. Infect. Dis. 45(9), 1230-1237 (2007).
    • (2007) Clin. Infect. Dis , vol.45 , Issue.9 , pp. 1230-1237
    • Gatanaga, H.1    Hayashida, T.2    Tsuchiya, K.3
  • 11
    • 84899620845 scopus 로고    scopus 로고
    • Efficacy of 400 mg efavirenz versus standard 600 mg dose in HIV-infected, antiretroviral-naive adults (ENCORE1): A randomised, double-blind, placebo-controlled, non-inferiority trial
    • Encore Study Group Puls R
    • Encore Study Group, Puls R, Amin J et al. Efficacy of 400 mg efavirenz versus standard 600 mg dose in HIV-infected, antiretroviral-naive adults (ENCORE1): a randomised, double-blind, placebo-controlled, non-inferiority trial. Lancet 383(9927), 1474-1482 (2014).
    • (2014) Lancet , vol.383 , Issue.9927 , pp. 1474-1482
    • Amin, J.1
  • 12
    • 84937512973 scopus 로고    scopus 로고
    • Efficacy and safety of efavirenz 400 mg daily versus 600 mg daily: 96-week data from the randomised, double-blind, placebo-controlled, noninferiority ENCORE1 study
    • Encore1 Study Group. Efficacy and safety of efavirenz 400 mg daily versus 600 mg daily: 96-week data from the randomised, double-blind, placebo-controlled, noninferiority ENCORE1 study. Lancet Infect. Dis. 15(7), 793-802 (2015).
    • (2015) Lancet Infect. Dis , vol.15 , Issue.7 , pp. 793-802
    • Study Group, E.1
  • 13
    • 84904561614 scopus 로고    scopus 로고
    • Functional CYP2B6 variants and virologic response to an efavirenz-containing regimen in Port-au-Prince
    • Haas DW, Severe P, Jean Juste MA, Pape JW, Fitzgerald DW. Functional CYP2B6 variants and virologic response to an efavirenz-containing regimen in Port-au-Prince, Haiti. J. Antimicrob. Chemother. 69(8), 2187-2190 (2014).
    • (2014) Haiti. J. Antimicrob. Chemother , vol.69 , Issue.8 , pp. 2187-2190
    • Haas, D.W.1    Severe, P.2    Jean Juste, M.A.3    Pape, J.W.4    Fitzgerald, D.W.5
  • 14
    • 0035808574 scopus 로고    scopus 로고
    • Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients
    • Marzolini C, Telenti A, Decosterd LA, Greub G, Biollaz J, Buclin T. Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients. AIDS 15(1), 71-75 (2001).
    • (2001) AIDS , vol.15 , Issue.1 , pp. 71-75
    • Marzolini, C.1    Telenti, A.2    Decosterd, L.A.3    Greub, G.4    Biollaz, J.5    Buclin, T.6
  • 15
    • 1042300270 scopus 로고    scopus 로고
    • Analyzing sleep abnormalities in HIV-infected patients treated with efavirenz
    • Gallego L, Barreiro P, Del Rio R et al. Analyzing sleep abnormalities in HIV-infected patients treated with efavirenz. Clin. Infect. Dis. 38(3), 430-432 (2004).
    • (2004) Clin. Infect. Dis , vol.38 , Issue.3 , pp. 430-432
    • Gallego, L.1    Barreiro, P.2    Del Rio, R.3
  • 16
    • 28144452516 scopus 로고    scopus 로고
    • Impact of efavirenz on neuropsychological performance and symptoms in HIVinfected individuals
    • Clifford DB, Evans S, Yang Y et al. Impact of efavirenz on neuropsychological performance and symptoms in HIVinfected individuals. Ann. Intern. Med. 143(10), 714-721 (2005).
    • (2005) Ann. Intern. Med , vol.143 , Issue.10 , pp. 714-721
    • Clifford, D.B.1    Evans, S.2    Yang, Y.3
  • 17
    • 28044459173 scopus 로고    scopus 로고
    • Prediction of neuropsychiatric adverse events associated with long-term efavirenz therapy, using plasma drug level monitoring
    • Gutierrez F, Navarro A, Padilla S et al. Prediction of neuropsychiatric adverse events associated with long-term efavirenz therapy, using plasma drug level monitoring. Clin. Infect. Dis. 41(11), 1648-1653 (2005).
    • (2005) Clin. Infect. Dis , vol.41 , Issue.11 , pp. 1648-1653
    • Gutierrez, F.1    Navarro, A.2    Padilla, S.3
  • 18
    • 79952115077 scopus 로고    scopus 로고
    • Efavirenz plasma concentrations did not predict cessation of therapy due to neuropsychiatric symptoms in a large randomized trial
    • Read TR, Carey D, Mallon P et al. Efavirenz plasma concentrations did not predict cessation of therapy due to neuropsychiatric symptoms in a large randomized trial. AIDS 23(16), 2222-2223 (2009).
    • (2009) AIDS , vol.23 , Issue.16 , pp. 2222-2223
    • Read, T.R.1    Carey, D.2    Mallon, P.3
  • 19
    • 34848907106 scopus 로고    scopus 로고
    • No observable correlation between central nervous system side effects and EFV plasma concentrations in Japanese HIV type 1-infected patients treated with EFV containing HAART
    • Takahashi M, Ibe S, Kudaka Y et al. No observable correlation between central nervous system side effects and EFV plasma concentrations in Japanese HIV type 1-infected patients treated with EFV containing HAART. AIDS Res. Hum. Retroviruses 23(8), 983-987 (2007).
    • (2007) AIDS Res. Hum. Retroviruses , vol.23 , Issue.8 , pp. 983-987
    • Takahashi, M.1    Ibe, S.2    Kudaka, Y.3
  • 20
    • 84903151392 scopus 로고    scopus 로고
    • Dose reduction of efavirenz: An observational study describing cost-effectiveness, pharmacokinetics and pharmacogenetics
    • Martin AS, Gomez AI, Garcia-Berrocal B et al. Dose reduction of efavirenz: an observational study describing cost-effectiveness, pharmacokinetics and pharmacogenetics. Pharmacogenomics 15(7), 997-1006 (2014).
    • (2014) Pharmacogenomics , vol.15 , Issue.7 , pp. 997-1006
    • Martin, A.S.1    Gomez, A.I.2    Garcia-Berrocal, B.3
  • 21
    • 84858259555 scopus 로고    scopus 로고
    • Cost-effectiveness of adding an agent that improves immune responses to initial antiretroviral therapy (ART) in HIV-infected patients: Guidance for drug development
    • Morris BL, Scott CA, Wilkin TJ et al. Cost-effectiveness of adding an agent that improves immune responses to initial antiretroviral therapy (ART) in HIV-infected patients: guidance for drug development. HIV Clin. Trials 13(1), 1-10 (2012).
    • (2012) HIV Clin. Trials , vol.13 , Issue.1 , pp. 1-10
    • Morris, B.L.1    Scott, C.A.2    Wilkin, T.J.3
  • 22
    • 84872577181 scopus 로고    scopus 로고
    • Economic savings versus health losses: The cost-effectiveness of generic antiretroviral therapy in the United States
    • Walensky RP, Sax PE, Nakamura YM et al. Economic savings versus health losses: the cost-effectiveness of generic antiretroviral therapy in the United States. Ann. Intern. Med. 158(2), 84-92 (2013).
    • (2013) Ann. Intern. Med , vol.158 , Issue.2 , pp. 84-92
    • Walensky, R.P.1    Sax, P.E.2    Nakamura, Y.M.3
  • 23
    • 84949049575 scopus 로고    scopus 로고
    • Bristol-Myers Squibb Statement on Sustiva (efavirenz) in the U.S.
    • Bristol-Myers Squibb Statement on Sustiva (efavirenz) in the U.S. (2014). http://news.bms.com/press-release/bristol-myers-squibb
    • , vol.2014
  • 25
    • 52649156033 scopus 로고    scopus 로고
    • Quantifying the decrement in utility from perceived side effects of combination antiretroviral therapies in patients with HIV
    • Braithwaite RS, Goulet J, Kudel I, Tsevat J, Justice AC. Quantifying the decrement in utility from perceived side effects of combination antiretroviral therapies in patients with HIV. Value Health 11(5), 975-979 (2008).
    • (2008) Value Health , vol.11 , Issue.5 , pp. 975-979
    • Braithwaite, R.S.1    Goulet, J.2    Kudel, I.3    Tsevat, J.4    Justice, A.C.5
  • 26
    • 69249104215 scopus 로고    scopus 로고
    • Cost effectiveness of pharmacogenetic testing for uridine diphosphate glucuronosyltransferase 1A1 before irinotecan administration for metastatic colorectal cancer
    • Gold HT, Hall MJ, Blinder V, Schackman BR. Cost effectiveness of pharmacogenetic testing for uridine diphosphate glucuronosyltransferase 1A1 before irinotecan administration for metastatic colorectal cancer. Cancer 115(17), 3858-3867 (2009).
    • (2009) Cancer , vol.115 , Issue.17 , pp. 3858-3867
    • Gold, H.T.1    Hall, M.J.2    Blinder, V.3    Schackman, B.R.4
  • 27
    • 0035869435 scopus 로고    scopus 로고
    • The cost effectiveness of combination antiretroviral therapy for HIV disease
    • Freedberg KA, Losina E, Weinstein MC et al. The cost effectiveness of combination antiretroviral therapy for HIV disease. N. Engl. J. Med. 344(11), 824-831 (2001).
    • (2001) N. Engl. J. Med , vol.344 , Issue.11 , pp. 824-831
    • Freedberg, K.A.1    Losina, E.2    Weinstein, M.C.3
  • 28
    • 53549095195 scopus 로고    scopus 로고
    • The cost-effectiveness of HLA-B∗5701 genetic screening to guide initial antiretroviral therapy for HIV
    • Schackman BR, Scott CA, Walensky RP, Losina E, Freedberg KA, Sax PE. The cost-effectiveness of HLA-B∗5701 genetic screening to guide initial antiretroviral therapy for HIV. AIDS 22(15), 2025-2033 (2008).
    • (2008) AIDS , vol.22 , Issue.15 , pp. 2025-2033
    • Schackman, B.R.1    Scott, C.A.2    Walensky, R.P.3    Losina, E.4    Freedberg, K.A.5    Sax, P.E.6
  • 29
    • 84925953518 scopus 로고    scopus 로고
    • The lifetime medical cost savings from preventing HIV in the United States
    • Schackman BR, Fleishman JA, Su AE et al. The lifetime medical cost savings from preventing HIV in the United States. Med. Care 53(4), 293-301 (2015).
    • (2015) Med. Care , vol.53 , Issue.4 , pp. 293-301
    • Schackman, B.R.1    Fleishman, J.A.2    Su, A.E.3
  • 30
    • 1842296349 scopus 로고    scopus 로고
    • Plasma viral load and CD4+ lymphocytes as prognostic markers of HIV-1 infection
    • Mellors JW, Munõz A, Giorgi JV et al. Plasma viral load and CD4+ lymphocytes as prognostic markers of HIV-1 infection. Ann. Intern. Med. 126(12), 946-954 (1997).
    • (1997) Ann. Intern. Med , vol.126 , Issue.12 , pp. 946-954
    • Mellors, J.W.1    Munõz, A.2    Giorgi, J.V.3
  • 31
    • 0032515391 scopus 로고    scopus 로고
    • Seage GR III the cost-effectiveness of preventing AIDS-related opportunistic infections
    • Freedberg KA, Scharfstein JA, Seage GR III The cost-effectiveness of preventing AIDS-related opportunistic infections. JAMA 279(2), 130-136 (1998).
    • (1998) JAMA , vol.279 , Issue.2 , pp. 130-136
    • Freedberg, K.A.1    Scharfstein, J.A.2
  • 33
    • 72849122861 scopus 로고    scopus 로고
    • Racial and sex disparities in life expectancy losses among HIV-infected persons in the United States: Impact of risk behavior, late initiation, and early discontinuation of antiretroviral therapy
    • Losina E, Schackman BR, Sadownik SN et al. Racial and sex disparities in life expectancy losses among HIV-infected persons in the United States: impact of risk behavior, late initiation, and early discontinuation of antiretroviral therapy. Clin. Infect. Dis. 49(10), 1570-1578 (2009).
    • (2009) Clin. Infect. Dis. , vol.49 , Issue.10 , pp. 1570-1578
    • Losina, E.1    Schackman, B.R.2    Sadownik, S.N.3
  • 34
    • 84926658499 scopus 로고    scopus 로고
    • The clinical role and cost-effectiveness of long-acting antiretroviral therapy
    • Ross EL, Weinstein MC, Schackman BR et al. The clinical role and cost-effectiveness of long-acting antiretroviral therapy. Clin. Infect. Dis. 60(7), 1102-1110 (2015).
    • (2015) Clin. Infect. Dis , vol.60 , Issue.7 , pp. 1102-1110
    • Ross, E.L.1    Weinstein, M.C.2    Schackman, B.R.3
  • 35
    • 84857529579 scopus 로고    scopus 로고
    • Adherence to antiretroviral treatment and correlation with risk of hospitalization among commercially insured HIV patients in the United States
    • Sax PE, Meyers JL, Mugavero M, Davis KL. Adherence to antiretroviral treatment and correlation with risk of hospitalization among commercially insured HIV patients in the United States. PLoS ONE 7(2), e31591 (2012).
    • (2012) PLoS ONE , vol.7 , Issue.2 , pp. e31591
    • Sax, P.E.1    Meyers, J.L.2    Mugavero, M.3    Davis, K.L.4
  • 36
    • 33845354174 scopus 로고    scopus 로고
    • Tenofovir disoproxil fumarate, emtricitabine, and efavirenz versus fixed-dose zidovudine/lamivudine and efavirenz in antiretroviral-naive patients: Virologic, immunologic, and morphologic changes-A 96-week analysis
    • Pozniak AL, Gallant JE, Dejesus E et al. Tenofovir disoproxil fumarate, emtricitabine, and efavirenz versus fixed-dose zidovudine/lamivudine and efavirenz in antiretroviral-naive patients: virologic, immunologic, and morphologic changes-a 96-week analysis. J. Acquir. Immune Defic. Syndr. 43(5), 535-540 (2006).
    • (2006) J. Acquir. Immune Defic. Syndr , vol.43 , Issue.5 , pp. 535-540
    • Pozniak, A.L.1    Gallant, J.E.2    Dejesus, E.3
  • 37
    • 84862876886 scopus 로고    scopus 로고
    • Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir versus co-formulated efavirenz, emtricitabine, and tenofovir for initial treatment of HIV-1 infection: A randomised, double-blind, Phase 3 trial, analysis of results after 48 weeks
    • Sax PE, Dejesus E, Mills A et al. Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir versus co-formulated efavirenz, emtricitabine, and tenofovir for initial treatment of HIV-1 infection: a randomised, double-blind, Phase 3 trial, analysis of results after 48 weeks. Lancet 379(9835), 2439-2448 (2012).
    • (2012) Lancet , vol.379 , Issue.9835 , pp. 2439-2448
    • Sax, P.E.1    Dejesus, E.2    Mills, A.3
  • 39
    • 77951852447 scopus 로고    scopus 로고
    • Late presentation for human immunodeficiency virus care in the United States and Canada
    • Althoff KN, Gange SJ, Klein MB et al. Late presentation for human immunodeficiency virus care in the United States and Canada. Clin. Infect. Dis. 50(11), 1512-1520 (2010).
    • (2010) Clin. Infect. Dis. , vol.50 , Issue.11 , pp. 1512-1520
    • Althoff, K.N.1    Gange, S.J.2    Klein, M.B.3
  • 40
    • 79954488050 scopus 로고    scopus 로고
    • Antiretroviral therapy adherence, medication use, and health care costs during 3 years of a community pharmacy medication therapy management program for Medi-Cal beneficiaries with HIV/AIDS
    • Hirsch JD, Gonzales M, Rosenquist A, Miller TA, Gilmer TP, Best BM. Antiretroviral therapy adherence, medication use, and health care costs during 3 years of a community pharmacy medication therapy management program for Medi-Cal beneficiaries with HIV/AIDS. J. Manag. Care Pharm. 17(3), 213-223 (2011).
    • (2011) J. Manag. Care Pharm , vol.17 , Issue.3 , pp. 213-223
    • Hirsch, J.D.1    Gonzales, M.2    Rosenquist, A.3    Miller, T.A.4    Gilmer, T.P.5    Best, B.M.6
  • 41
    • 84885216903 scopus 로고    scopus 로고
    • Increasing rate of TAMs and etravirine resistance in HIV-1-infected adults between 12 and 24 months of treatment: The VOLTART cohort study in Côte d'Ivoire
    • Messou E, Chaix ML, Gabillard D et al. Increasing rate of TAMs and etravirine resistance in HIV-1-infected adults between 12 and 24 months of treatment: the VOLTART cohort study in Côte d'Ivoire, West Africa. J. Acquir. Immune Defic. Syndr. 64(2), 211-219 (2013).
    • (2013) West Africa. J. Acquir. Immune Defic. Syndr , vol.64 , Issue.2 , pp. 211-219
    • Messou, E.1    Chaix, M.L.2    Gabillard, D.3
  • 42
    • 18344385139 scopus 로고    scopus 로고
    • Hospital and outpatient health services utilization among HIV-infected patients in care in 1999
    • HIV Research Network
    • HIV Research Network. Hospital and outpatient health services utilization among HIV-infected patients in care in 1999. J. Acquir. Immune Defic. Syndr. 30(1), 21-26 (2002).
    • (2002) J. Acquir. Immune Defic. Syndr , vol.30 , Issue.1 , pp. 21-26
  • 43
    • 84878098923 scopus 로고    scopus 로고
    • Cost-effectiveness analysis of UGT1A1 genetic testing to inform antiretroviral prescribing in HIV disease
    • Schackman BR, Haas DW, Becker JE et al. Cost-effectiveness analysis of UGT1A1 genetic testing to inform antiretroviral prescribing in HIV disease. Antivir. Ther. 18(3), 399-408 (2013).
    • (2013) Antivir. Ther , vol.18 , Issue.3 , pp. 399-408
    • Schackman, B.R.1    Haas, D.W.2    Becker, J.E.3
  • 44
    • 84863722466 scopus 로고    scopus 로고
    • Discontinuation of Atripla as first-line therapy in HIV-1 infected individuals
    • Scourfield A, Zheng J, Chinthapalli S et al. Discontinuation of Atripla as first-line therapy in HIV-1 infected individuals. AIDS 26(11), 1399-1401 (2012).
    • (2012) AIDS , vol.26 , Issue.11 , pp. 1399-1401
    • Scourfield, A.1    Zheng, J.2    Chinthapalli, S.3
  • 45
    • 84949049577 scopus 로고    scopus 로고
    • Medicare Physician Fee Schedule
    • Medicare Physician Fee Schedule (2013). www.cms.gov/apps/physician-fee-schedule/overview.aspx
    • (2013)
  • 46
    • 79851482408 scopus 로고    scopus 로고
    • Association of pharmacogenetic markers with premature discontinuation of first-line anti-HIV therapy: An observational cohort study
    • Lubomirov R, Colombo S, Di Iulio J et al. Association of pharmacogenetic markers with premature discontinuation of first-line anti-HIV therapy: an observational cohort study. J. Infect. Dis. 203(2), 246-257 (2011).
    • (2011) J. Infect. Dis. , vol.203 , Issue.2 , pp. 246-257
    • Lubomirov, R.1    Colombo, S.2    Di Iulio, J.3
  • 47
    • 77749271329 scopus 로고    scopus 로고
    • Maraviroc versus efavirenz, both in combination with zidovudine-lamivudine, for the treatment of antiretroviral-naive subjects with CCR5-tropic HIV-1 infection
    • Cooper DA, Heera J, Goodrich J et al. Maraviroc versus efavirenz, both in combination with zidovudine-lamivudine, for the treatment of antiretroviral-naive subjects with CCR5-tropic HIV-1 infection. J. Infect. Dis. 201(6), 803-813 (2010).
    • (2010) J. Infect. Dis , vol.201 , Issue.6 , pp. 803-813
    • Cooper, D.A.1    Heera, J.2    Goodrich, J.3
  • 48
    • 11144357656 scopus 로고    scopus 로고
    • Comparison of first-line antiretroviral therapy with regimens including nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: A randomised open-label trial, the 2NN Study
    • Van Leth F, Phanuphak P, Ruxrungtham K et al. Comparison of first-line antiretroviral therapy with regimens including nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: a randomised open-label trial, the 2NN Study. Lancet 363(9417), 1253-1263 (2004).
    • (2004) Lancet , vol.363 , Issue.9417 , pp. 1253-1263
    • Van Leth, F.1    Phanuphak, P.2    Ruxrungtham, K.3
  • 49
    • 63849240305 scopus 로고    scopus 로고
    • Vivo analysis of efavirenz metabolism in individuals with impaired CYP2A6 function
    • Di Iulio J, Fayet A, Arab-Alameddine M et al. In vivo analysis of efavirenz metabolism in individuals with impaired CYP2A6 function. Pharmacogenet. Genomics 19(4), 300-309 (2009).
    • (2009) Pharmacogenet. Genomics , vol.19 , Issue.4 , pp. 300-309
    • Di Iulio, J.1    Fayet, A.2    Arab-Alameddine, M.3
  • 50
    • 84904581820 scopus 로고    scopus 로고
    • Secondary metabolism pathway polymorphisms and plasma efavirenz concentrations in HIV-infected adults with CYP2B6 slow metabolizer genotypes
    • Haas DW, Kwara A, Richardson DM et al. Secondary metabolism pathway polymorphisms and plasma efavirenz concentrations in HIV-infected adults with CYP2B6 slow metabolizer genotypes. J. Antimicrob. Chemother. 69(8), 2175-2182 (2014).
    • (2014) J. Antimicrob. Chemother , vol.69 , Issue.8 , pp. 2175-2182
    • Haas, D.W.1    Kwara, A.2    Richardson, D.M.3
  • 51
    • 63849281439 scopus 로고    scopus 로고
    • CYP2B6 (c516G->T) and CYP2A6 (∗9B and/or∗17) polymorphisms are independent predictors of efavirenz plasma concentrations in HIV-infected patients
    • Kwara A, Lartey M, Sagoe KW, Rzek NL, Court MH. CYP2B6 (c.516G->T) and CYP2A6 (∗9B and/or∗17) polymorphisms are independent predictors of efavirenz plasma concentrations in HIV-infected patients. Br. J. Clin. Pharmacol. 67(4), 427-436 (2009).
    • (2009) Br. J. Clin. Pharmacol , vol.67 , Issue.4 , pp. 427-436
    • Kwara, A.1    Lartey, M.2    Sagoe, K.W.3    Rzek, N.L.4    Court, M.H.5
  • 52
    • 84898050780 scopus 로고    scopus 로고
    • Lower pill burden and once-daily antiretroviral treatment regimens for HIV Infection: A meta-analysis of randomized controlled trials
    • Nachega JB, Parienti JJ, Uthman OA et al. Lower pill burden and once-daily antiretroviral treatment regimens for HIV infection: a meta-analysis of randomized controlled trials. Clin. Infect. Dis. 58(9), 1297-1307 (2014).
    • (2014) Clin. Infect. Dis , vol.58 , Issue.9 , pp. 1297-1307
    • Nachega, J.B.1    Parienti, J.J.2    Uthman, O.A.3


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