PXR and CAR single nucleotide polymorphisms influence plasma efavirenz levels in South African HIV/AIDS patients

BMC Medical Genetics

Volumn 13, Issue , 2012, Pages

  Swart, Marelize ^a   Whitehorn, Heather ^a   Ren, Yuan ^a   Smith, Peter ^a   Ramesar, Rajkumar S ^a   Dandara, Collet ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

CAR; Efavirenz; HIV AIDS; Pharmacogenetics; PXR; South Africa

Indexed keywords

CONSTITUTIVE ANDROSTANE RECEPTOR; EFAVIRENZ; PREGNANE X RECEPTOR;

ADULT; AIDS PATIENT; ARTICLE; ASIAN; CAUCASIAN; CONTROLLED STUDY; DNA BINDING; DNA SEQUENCE; DRUG BLOOD LEVEL; FEMALE; GENE; GENE IDENTIFICATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; MAJOR CLINICAL STUDY; MALE; NUCLEAR RECEPTOR NR1I2 GENE; NUCLEAR RECEPTOR NR1I3 GENE; NUCLEOTIDE SEQUENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SOUTH AFRICA;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; BENZOXAZINES; GENE FREQUENCY; HAPLOTYPES; HIV INFECTIONS; HUMANS; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID;

EID: 84869862527     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-13-112     Document Type: Article

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