Connectivity mapping using a combined gene signature from multiple colorectal cancer datasets identified candidate drugs including existing chemotherapies

BMC Systems Biology

Volumn 9, Issue 5, 2015, Pages

  Wen, Qing ^a   O'Reilly, Paul ^a   Dunne, Philip D ^a   Lawler, Mark ^a   Van Schaeybroeck, Sandra ^a   Salto Tellez, Manuel ^a   Hamilton, Peter ^a   Zhang, Shu Dong ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Colorectal cancer; Connectivity mapping; Etoposide; Gene signature; Irinotecan; Multiple datasets; Systems approach

Indexed keywords

ANTINEOPLASTIC AGENT;

BIOLOGY; CHROMOSOMAL MAPPING; COLORECTAL NEOPLASMS; DRUG DEVELOPMENT; GENETIC DATABASE; GENETICS; HUMAN; PROCEDURES;

ANTINEOPLASTIC AGENTS; CHROMOSOME MAPPING; COLORECTAL NEOPLASMS; COMPUTATIONAL BIOLOGY; DATABASES, GENETIC; DRUG DISCOVERY; HUMANS;

EID: 84961637001     PISSN: None     EISSN: 17520509     Source Type: Journal    
DOI: 10.1186/1752-0509-9-S5-S4     Document Type: Article

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