메뉴 건너뛰기




Volumn 6, Issue 1, 2014, Pages 28-42

Transcriptomic changes induced by mycophenolic acid in gastric cancer cells

Author keywords

Drug repurposing; Microarray; MPA; Regulatory networks

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; AURORA A KINASE; AURORA B KINASE; BUB1 RELATED PROTEIN; CELL CYCLE PROTEIN 20; CYCLIN A2; CYCLIN B1; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 5; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN E; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FAS ANTIGEN; MYCOPHENOLIC ACID; PROTEIN P53; PROTEIN TYROSINE PHOSPHATASE; RIBONUCLEOTIDE REDUCTASE; SMAD3 PROTEIN; THIOREDOXIN INTERACTING PROTEIN; TRANSCRIPTION FACTOR E2F7; TRANSCRIPTOME;

EID: 84889689705     PISSN: None     EISSN: 19438141     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (32)

References (35)
  • 2
    • 0034045586 scopus 로고    scopus 로고
    • Mycophenolate mofetil and its mechanisms of action
    • Allison AC and Eugui EM. Mycophenolate mofetil and its mechanisms of action. Immunopharmacology 2000; 47: 85-118.
    • (2000) Immunopharmacology , vol.47 , pp. 85-118
    • Allison, A.C.1    Eugui, E.M.2
  • 3
    • 0016823448 scopus 로고
    • IMP dehydrogenase, an enzyme linked with proliferation and malignancy
    • Jackson RC, Weber G and Morris HP. IMP dehydrogenase, an enzyme linked with proliferation and malignancy. Nature 1975; 256: 331-333.
    • (1975) Nature , vol.256 , pp. 331-333
    • Jackson, R.C.1    Weber, G.2    Morris, H.P.3
  • 5
    • 77957859532 scopus 로고    scopus 로고
    • Overexpression of inosine 5'-monophosphate dehydrogenase type II mediates chemoresistance to human osteosarcoma cells
    • Fellenberg J, Kunz P, Sahr H and Depeweg D. Overexpression of inosine 5'-monophosphate dehydrogenase type II mediates chemoresistance to human osteosarcoma cells. PLoS One 2010; 5: e12179.
    • (2010) PLoS One , vol.5
    • Fellenberg, J.1    Kunz, P.2    Sahr, H.3    Depeweg, D.4
  • 7
    • 27644566143 scopus 로고    scopus 로고
    • Mechanisms of action of mycophenolate mofetil in preventing acute and chronic allograft rejection
    • Allison AC and Eugui EM. Mechanisms of action of mycophenolate mofetil in preventing acute and chronic allograft rejection. Transplantation 2005; 80: S181-190.
    • (2005) Transplantation , vol.80
    • Allison, A.C.1    Eugui, E.M.2
  • 8
  • 9
    • 14044257924 scopus 로고    scopus 로고
    • Cell cycle specific induction of HL-60 cell differentiation and apoptosis by mycophenolic acid
    • Gortz A, Franklin TJ, Dive C and Hickman JA. Cell cycle specific induction of HL-60 cell differentiation and apoptosis by mycophenolic acid. Cell Death Differ 1997; 4: 787-795.
    • (1997) Cell Death Differ , vol.4 , pp. 787-795
    • Gortz, A.1    Franklin, T.J.2    Dive, C.3    Hickman, J.A.4
  • 10
    • 34249891363 scopus 로고    scopus 로고
    • Antiproliferative and apoptotic effects of mycophenolic acid in human B-cell non-Hodgkin lymphomas
    • Vegso G, Sebestyen A, Paku S, Barna G, Hajdu M, Toth M, Jaray J and Kopper L. Antiproliferative and apoptotic effects of mycophenolic acid in human B-cell non-Hodgkin lymphomas. Leuk Res 2007; 31: 1003-1008.
    • (2007) Leuk Res , vol.31 , pp. 1003-1008
    • Vegso, G.1    Sebestyen, A.2    Paku, S.3    Barna, G.4    Hajdu, M.5    Toth, M.6    Jaray, J.7    Kopper, L.8
  • 13
    • 0028181387 scopus 로고
    • Anti-tumor activity of mycophenolate mofetil against human and mouse tumors in vivo
    • Tressler RJ, Garvin LJ and Slate DL. Anti-tumor activity of mycophenolate mofetil against human and mouse tumors in vivo. Int J Cancer 1994; 57: 568-573.
    • (1994) Int J Cancer , vol.57 , pp. 568-573
    • Tressler, R.J.1    Garvin, L.J.2    Slate, D.L.3
  • 14
    • 84888811354 scopus 로고    scopus 로고
    • Delineation of biological and molecular mechanisms underlying the anticancer activities of mycophenolic acid
    • Epub ahead of print
    • Dun B, Xu H, Sharma A, Liu H, Yu H, Yi B, Liu X, He M, Zeng L and She JX. Delineation of biological and molecular mechanisms underlying the anticancer activities of mycophenolic acid. Int J Clin Exp Pathol 2013; [Epub ahead of print].
    • (2013) Int J Clin Exp Pathol
    • Dun, B.1    Xu, H.2    Sharma, A.3    Liu, H.4    Yu, H.5    Yi, B.6    Liu, X.7    He, M.8    Zeng, L.9    She, J.X.10
  • 15
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Article3
    • Smyth GK. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 2004; 3: Article3.
    • (2004) Stat Appl Genet Mol Biol , pp. 3
    • Smyth, G.K.1
  • 16
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Statist Soc B 1995; 57: 289-300.
    • (1995) J R Statist Soc B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 17
    • 65449124221 scopus 로고    scopus 로고
    • A modified hyperplane clustering algorithm allows for efficient and accurate clustering of extremely large datasets
    • Sharma A, Podolsky R, Zhao J and McIndoe RA. A modified hyperplane clustering algorithm allows for efficient and accurate clustering of extremely large datasets. Bioinformatics 2009; 25: 1152-1157.
    • (2009) Bioinformatics , vol.25 , pp. 1152-1157
    • Sharma, A.1    Podolsky, R.2    Zhao, J.3    McIndoe, R.A.4
  • 18
    • 33846689706 scopus 로고    scopus 로고
    • Using GOstats to test gene lists for GO term association
    • Falcon S and Gentleman R. Using GOstats to test gene lists for GO term association. Bioinformatics 2007; 23: 257-258.
    • (2007) Bioinformatics , vol.23 , pp. 257-258
    • Falcon, S.1    Gentleman, R.2
  • 22
    • 0029317904 scopus 로고
    • Cyclin-dependent protein kinases: Key regulators of the eukaryotic cell cycle
    • Nigg EA. Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle. Bioessays 1995; 17: 471-480.
    • (1995) Bioessays , vol.17 , pp. 471-480
    • Nigg, E.A.1
  • 23
    • 1842591945 scopus 로고    scopus 로고
    • Redefining clinical response in psoriasis: Targeting the pathological basis of disease
    • Ortonne JP. Redefining clinical response in psoriasis: targeting the pathological basis of disease. J Drugs Dermatol 2004; 3: 13-20.
    • (2004) J Drugs Dermatol , vol.3 , pp. 13-20
    • Ortonne, J.P.1
  • 24
    • 36248990364 scopus 로고    scopus 로고
    • FOXM1, a typical proliferation-associated transcription factor
    • Wierstra I and Alves J. FOXM1, a typical proliferation-associated transcription factor. Biol Chem 2007; 388: 1257-1274.
    • (2007) Biol Chem , vol.388 , pp. 1257-1274
    • Wierstra, I.1    Alves, J.2
  • 27
    • 84865164864 scopus 로고    scopus 로고
    • TP53INP1, a tumor suppressor, interacts with LC3 and ATG8-family proteins through the LC3-interacting region (LIR) and promotes autophagy-dependent cell death
    • Seillier M, Peuget S, Gayet O, Gauthier C, N'Guessan P, Monte M, Carrier A, Iovanna JL and Dusetti NJ. TP53INP1, a tumor suppressor, interacts with LC3 and ATG8-family proteins through the LC3-interacting region (LIR) and promotes autophagy-dependent cell death. Cell Death Differ 2012; 19: 1525-153
    • (2012) Cell Death Differ , vol.19 , pp. 1525-1531
    • Seillier, M.1    Peuget, S.2    Gayet, O.3    Gauthier, C.4    N'Guessan, P.5    Monte, M.6    Carrier, A.7    Iovanna, J.L.8    Dusetti, N.J.9
  • 30
    • 79954627742 scopus 로고    scopus 로고
    • The cancer/testis antigen prostate-associated gene 4 (PAGE4) is a highly intrinsically disordered protein
    • Zeng Y, He Y, Yang F, Mooney SM, Getzenberg RH, Orban J and Kulkarni P. The cancer/testis antigen prostate-associated gene 4 (PAGE4) is a highly intrinsically disordered protein. J Biol Chem 2011; 286: 13985-13994.
    • (2011) J Biol Chem , vol.286 , pp. 13985-13994
    • Zeng, Y.1    He, Y.2    Yang, F.3    Mooney, S.M.4    Getzenberg, R.H.5    Orban, J.6    Kulkarni, P.7
  • 31
    • 24044551995 scopus 로고    scopus 로고
    • PI3K/Akt/mTOR pathway as a target for cancer therapy
    • Morgensztern D and McLeod HL. PI3K/Akt/mTOR pathway as a target for cancer therapy. Anticancer Drugs 2005; 16: 797-803.
    • (2005) Anticancer Drugs , vol.16 , pp. 797-803
    • Morgensztern, D.1    McLeod, H.L.2
  • 34
    • 0037204952 scopus 로고    scopus 로고
    • The Fas signaling pathway: More than a paradigm
    • Wajant H. The Fas signaling pathway: more than a paradigm. Science 2002; 296: 1635-1636.
    • (2002) Science , vol.296 , pp. 1635-1636
    • Wajant, H.1
  • 35


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.