Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain

FASEB Journal

Volumn 30, Issue 1, 2016, Pages 54-65

  Zarpelon, Ana C ^a   Rodrigues, Francielle C ^a   Lopes, Alexandre H ^b   Souza, Guilherme R ^b   Carvalho, Thacyana T ^a   Pinto, Larissa G ^b   Xu, Damo ^c   Ferreira, Sergio H ^b   Alves Filho, Jose C ^b   McInnes, Iain B ^c   Ryffel, Bernhard ^d,e   Quesniaux, Valérie F J ^d,e   Reverchon, Flora ^d,e   Mortaud, Stéphane ^d,e   Menuet, Arnaud ^d,e   Liew, Foo Y ^c,f   Cunha, Fernando Q ^b   Cunha, Thiago M ^b   Verri, Waldiceu A ^a  

^a STATE UNIVERSITY OF LONDRINA   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

^d Laboratoire d'Immunologie et Embryologie Moleculaires Orleans   (France)

^e UNIVERSITÉ D'ORLÉANS   (France)

^f SOOCHOW UNIVERSITY   (China)

Author keywords

Glial cells; Hyperalgesia; MAPK; mTOR; NF B

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 AMINOADIPIC ACID; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALARMIN; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; FLUOROCITRIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN; MINOCYCLINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PYRROLIDINE DITHIOCARBAMATE; RAPAMYCIN; RECOMBINANT CYTOKINE; RECOMBINANT INTERLEUKIN 33; RECOMBINANT INTERLEUKIN 33 RECEPTOR; RECOMBINANT RECEPTOR; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; WORTMANNIN; IL33 PROTEIN, MOUSE; INTERLEUKIN 33;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CHRONIC CONSTRICTION INJURY; CONTROLLED STUDY; CYTOKINE PRODUCTION; EXPERIMENTAL MODEL; MALE; MECHANICAL HYPERALGESIA; MICROGLIA; MOUSE; NEUROPATHIC PAIN; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; SCIATIC NERVE; SIGNAL TRANSDUCTION; SPINAL CORD; SPINAL CORD CELL CULTURE; ANIMAL; GENETICS; HYPERALGESIA; KNOCKOUT MOUSE; METABOLISM; NEURALGIA; PAIN THRESHOLD; PATHOPHYSIOLOGY; PHYSIOLOGY;

ALARMINS; ANIMALS; ASTROCYTES; HYPERALGESIA; INTERLEUKIN-33; MICE, KNOCKOUT; MICROGLIA; NEURALGIA; OLIGODENDROGLIA; PAIN THRESHOLD; PHOSPHATIDYLINOSITOL 3-KINASES; SIGNAL TRANSDUCTION; SPINAL CORD;

EID: 84961566047     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.14-267146     Document Type: Article

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