-
1
-
-
84877329207
-
PPARgamma signaling and metabolism: The good, the bad and the future
-
Ahmadian M, Suh JM, Hah N, Liddle C, Atkins AR, Downes M, Evans RM. PPARgamma signaling and metabolism: the good, the bad and the future. Nat Med 19: 557-566, 2013.
-
(2013)
Nat Med
, vol.19
, pp. 557-566
-
-
Ahmadian, M.1
Suh, J.M.2
Hah, N.3
Liddle, C.4
Atkins, A.R.5
Downes, M.6
Evans, R.M.7
-
2
-
-
0942276496
-
PPARgamma activation, by reducing oxidative stress, increases NO bioavailability in coronary arterioles of mice with Type 2 diabetes
-
Bagi Z, Koller A, Kaley G. PPARgamma activation, by reducing oxidative stress, increases NO bioavailability in coronary arterioles of mice with Type 2 diabetes. Am J Physiol Heart Circ Physiol 286: H742-H748, 2004.
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.286
, pp. H742-H748
-
-
Bagi, Z.1
Koller, A.2
Kaley, G.3
-
3
-
-
0033213637
-
PPAR gamma is required for placental, cardiac, and adipose tissue development
-
Barak Y, Nelson MC, Ong ES, Jones YZ, Ruiz-Lozano P, Chien KR, Koder A, Evans RM. PPAR gamma is required for placental, cardiac, and adipose tissue development. Mol Cell 4: 585-595, 1999.
-
(1999)
Mol Cell
, vol.4
, pp. 585-595
-
-
Barak, Y.1
Nelson, M.C.2
Ong, E.S.3
Jones, Y.Z.4
Ruiz-Lozano, P.5
Chien, K.R.6
Koder, A.7
Evans, R.M.8
-
4
-
-
0033599038
-
Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension
-
Barroso I, Gurnell M, Crowley VE, Agostini M, Schwabe JW, Soos MA, Maslen GL, Williams TD, Lewis H, Schafer AJ, Chatterjee VK, O’Rahilly S. Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension. Nature 402: 880-883, 1999.
-
(1999)
Nature
, vol.402
, pp. 880-883
-
-
Barroso, I.1
Gurnell, M.2
Crowley, V.E.3
Agostini, M.4
Schwabe, J.W.5
Soos, M.A.6
Maslen, G.L.7
Williams, T.D.8
Lewis, H.9
Schafer, A.J.10
Chatterjee, V.K.11
O’Rahilly, S.12
-
5
-
-
31744435022
-
Peroxisome proliferator activated receptor gamma regulates angiotensin II-stimulated phosphate dylinositol 3-kinase and mitogen-activated protein kinase in blood vessels in vivo
-
Benkirane K, Viel EC, Amiri F, Schiffrin EL. Peroxisome proliferator activated receptor gamma regulates angiotensin II-stimulated phosphate dylinositol 3-kinase and mitogen-activated protein kinase in blood vessels in vivo. Hypertension 47: 102-108, 2006.
-
(2006)
Hypertension
, vol.47
, pp. 102-108
-
-
Benkirane, K.1
Viel, E.C.2
Amiri, F.3
Schiffrin, E.L.4
-
6
-
-
42049101837
-
Interference with PPARgamma signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling
-
Beyer AM, Baumbach GL, Halabi CM, Modrick ML, Lynch CM, Gerhold TD, Ghoneim SM, de Lange WJ, Keen HL, Tsai YS, Maeda N, Sigmund CD, Faraci FM. Interference with PPARgamma signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling. Hypertension 51: 867-871, 2008.
-
(2008)
Hypertension
, vol.51
, pp. 867-871
-
-
Beyer, A.M.1
Baumbach, G.L.2
Halabi, C.M.3
Modrick, M.L.4
Lynch, C.M.5
Gerhold, T.D.6
Ghoneim, S.M.7
de Lange, W.J.8
Keen, H.L.9
Tsai, Y.S.10
Maeda, N.11
Sigmund, C.D.12
Faraci, F.M.13
-
7
-
-
53249111805
-
Endothelium-specific interference with peroxisome proliferator-activated receptor gamma causes cerebral vascular dysfunction in response to a high-fat diet
-
Beyer AM, de Lange WJ, Halabi CM, Modrick ML, Keen HL, Faraci FM, Sigmund CD. Endothelium-specific interference with peroxisome proliferator-activated receptor gamma causes cerebral vascular dysfunction in response to a high-fat diet. Circ Res 103: 654-661, 2008.
-
(2008)
Circ Res
, vol.103
, pp. 654-661
-
-
Beyer, A.M.1
de Lange, W.J.2
Halabi, C.M.3
Modrick, M.L.4
Keen, H.L.5
Faraci, F.M.6
Sigmund, C.D.7
-
8
-
-
84907598119
-
Interference with peroxisome proliferator-activated receptor-gamma in vascular smooth muscle causes baroreflex impairment and autonomic dysfunction
-
Borges GR, Morgan DA, Ketsawatsomkron P, Mickle AD, Thompson AP, Cassell MD, Mohapatra DP, Rahmouni K, Sigmund CD. Interference with peroxisome proliferator-activated receptor-gamma in vascular smooth muscle causes baroreflex impairment and autonomic dysfunction. Hypertension 64: 590-596, 2014.
-
(2014)
Hypertension
, vol.64
, pp. 590-596
-
-
Borges, G.R.1
Morgan, D.A.2
Ketsawatsomkron, P.3
Mickle, A.D.4
Thompson, A.P.5
Cassell, M.D.6
Mohapatra, D.P.7
Rahmouni, K.8
Sigmund, C.D.9
-
9
-
-
0037231474
-
Peroxisome proliferator-activated receptor gamma ligands increase release of nitric oxide from endothelial cells
-
Calnek DS, Mazzella L, Roser S, Roman J, Hart CM. Peroxisome proliferator-activated receptor gamma ligands increase release of nitric oxide from endothelial cells. Arterioscler Thromb Vasc Biol 23: 52-57, 2003.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 52-57
-
-
Calnek, D.S.1
Mazzella, L.2
Roser, S.3
Roman, J.4
Hart, C.M.5
-
10
-
-
68549118949
-
Estrous cycle-dependent neurovascular dysfunction induced by angiotensin II in the mouse neocortex
-
Capone C, Anrather J, Milner TA, Iadecola C. Estrous cycle-dependent neurovascular dysfunction induced by angiotensin II in the mouse neocortex. Hypertension 54: 302-307, 2009.
-
(2009)
Hypertension
, vol.54
, pp. 302-307
-
-
Capone, C.1
Anrather, J.2
Milner, T.A.3
Iadecola, C.4
-
11
-
-
78651313012
-
The cerebrovascular dysfunction induced by slow pressor doses of angiotensin II precedes the development of hypertension
-
Capone C, Faraco G, Park L, Cao X, Davisson RL, Iadecola C. The cerebrovascular dysfunction induced by slow pressor doses of angiotensin II precedes the development of hypertension. Am J Physiol Heart Circ Physiol 300: H397-H407, 2011.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.300
, pp. H397-H407
-
-
Capone, C.1
Faraco, G.2
Park, L.3
Cao, X.4
Davisson, R.L.5
Iadecola, C.6
-
12
-
-
0028015713
-
Peroxisome proliferator-activated receptor (PPAR) gamma: Adipose-predominant expression and induction early in adipocyte differentiation
-
Chawla A, Schwarz EJ, Dimaculangan DD, Lazar MA. Peroxisome proliferator-activated receptor (PPAR) gamma: adipose-predominant expression and induction early in adipocyte differentiation. Endocrinology 135: 798-800, 1994.
-
(1994)
Endocrinology
, vol.135
, pp. 798-800
-
-
Chawla, A.1
Schwarz, E.J.2
Dimaculangan, D.D.3
Lazar, M.A.4
-
13
-
-
0033527162
-
PPARgamma agonists enhance human vascular endothelial adhesiveness by increasing ICAM-1 expression
-
Chen NG, Sarabia SF, Malloy PJ, Zhao XY, Feldman D, Reaven GM. PPARgamma agonists enhance human vascular endothelial adhesiveness by increasing ICAM-1 expression. Biochem Biophys Res Commun 263: 718-722, 1999.
-
(1999)
Biochem Biophys Res Commun
, vol.263
, pp. 718-722
-
-
Chen, N.G.1
Sarabia, S.F.2
Malloy, P.J.3
Zhao, X.Y.4
Feldman, D.5
Reaven, G.M.6
-
14
-
-
84864242097
-
Role of Nox isoforms in angiotensin II-induced oxidative stress and endothelial dysfunction in brain
-
Chrissobolis S, Banfi B, Sobey CG, Faraci FM. Role of Nox isoforms in angiotensin II-induced oxidative stress and endothelial dysfunction in brain. J Appl Physiol 113: 184-191, 2012.
-
(2012)
J Appl Physiol
, vol.113
, pp. 184-191
-
-
Chrissobolis, S.1
Banfi, B.2
Sobey, C.G.3
Faraci, F.M.4
-
15
-
-
3242746092
-
Cerebral vascular dysfunction mediated by superoxide in hyperhomocysteinemic mice
-
Dayal S, Arning E, Bottiglieri T, Boger RH, Sigmund CD, Faraci FM, Lentz SR. Cerebral vascular dysfunction mediated by superoxide in hyperhomocysteinemic mice. Stroke 35: 1957-1962, 2004.
-
(2004)
Stroke
, vol.35
, pp. 1957-1962
-
-
Dayal, S.1
Arning, E.2
Bottiglieri, T.3
Boger, R.H.4
Sigmund, C.D.5
Faraci, F.M.6
Lentz, S.R.7
-
16
-
-
0036924890
-
Deficiency of glutathione peroxidase-1 sensi- tizes hyperhomocysteinemic mice to endothelial dysfunction
-
Dayal S, Brown KL, Weydert CJ, Oberley LW, Arning E, Bottiglieri T, Faraci FM, Lentz SR. Deficiency of glutathione peroxidase-1 sensi- tizes hyperhomocysteinemic mice to endothelial dysfunction. Arterioscler Thromb Vasc Biol 22: 1996-2002, 2002.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 1996-2002
-
-
Dayal, S.1
Brown, K.L.2
Weydert, C.J.3
Oberley, L.W.4
Arning, E.5
Bottiglieri, T.6
Faraci, F.M.7
Lentz, S.R.8
-
17
-
-
84925770086
-
Role of peroxisome proliferator-activated receptor-gamma in vascular muscle in the cerebral circulation
-
De Silva TM, Modrick ML, Ketsawatsomkron P, Lynch C, Chu Y, Pelham CJ, Sigmund CD, Faraci FM. Role of peroxisome proliferator-activated receptor-gamma in vascular muscle in the cerebral circulation. Hypertension 64: 1088-1093, 2014.
-
(2014)
Hypertension
, vol.64
, pp. 1088-1093
-
-
De Silva, T.M.1
Modrick, M.L.2
Ketsawatsomkron, P.3
Lynch, C.4
Chu, Y.5
Pelham, C.J.6
Sigmund, C.D.7
Faraci, F.M.8
-
18
-
-
0033520304
-
Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway
-
Delerive P, Martin-Nizard F, Chinetti G, Trottein F, Fruchart JC, Najib J, Duriez P, Staels B. Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway. Circ Res 85: 394-402, 1999.
-
(1999)
Circ Res
, vol.85
, pp. 394-402
-
-
Delerive, P.1
Martin-Nizard, F.2
Chinetti, G.3
Trottein, F.4
Fruchart, J.C.5
Najib, J.6
Duriez, P.7
Staels, B.8
-
19
-
-
78649905840
-
Vascular endothelial function and hypertension: Insights and directions
-
Dharmashankar K, Widlansky ME. Vascular endothelial function and hypertension: insights and directions. Curr Hypertens Rep 12: 448-455, 2010.
-
(2010)
Curr Hypertens Rep
, vol.12
, pp. 448-455
-
-
Dharmashankar, K.1
Widlansky, M.E.2
-
20
-
-
11144248484
-
Ceramide-induced impairment of endothelial function is prevented by CuZn superoxide dismutase overexpression
-
Didion SP, Faraci FM. Ceramide-induced impairment of endothelial function is prevented by CuZn superoxide dismutase overexpression. Arterioscler Thromb Vasc Biol 25: 90-95, 2005.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 90-95
-
-
Didion, S.P.1
Faraci, F.M.2
-
21
-
-
0036783627
-
Superoxide contributes to vascular dysfunction in mice that express human renin and angiotensinogen
-
Didion SP, Ryan MJ, Baumbach GL, Sigmund CD, Faraci FM. Superoxide contributes to vascular dysfunction in mice that express human renin and angiotensinogen. Am J Physiol Heart Circ Physiol 283: H1569-H1576, 2002.
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.283
, pp. H1569-H1576
-
-
Didion, S.P.1
Ryan, M.J.2
Baumbach, G.L.3
Sigmund, C.D.4
Faraci, F.M.5
-
22
-
-
0037076294
-
Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II-infused rats: Role of peroxisome proliferator-activated receptor-gamma
-
Diep QN, El Mabrouk M, Cohn JS, Endemann D, Amiri F, Virdis A, Neves MF, Schiffrin EL. Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II-infused rats: role of peroxisome proliferator-activated receptor-gamma. Circulation 105: 2296-2302, 2002.
-
(2002)
Circulation
, vol.105
, pp. 2296-2302
-
-
Diep, Q.N.1
El Mabrouk, M.2
Cohn, J.S.3
Endemann, D.4
Amiri, F.5
Virdis, A.6
Neves, M.F.7
Schiffrin, E.L.8
-
23
-
-
26244453309
-
PROactive investigators. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): A randomised controlled trial
-
Dormandy JA, Charbonnel B, Eckland DJ, Erdmann E, Massi-Benedetti M, Moules IK, Skene AM, Tan MH, Lefebvre PJ, Murray GD, Standl E, Wilcox RG, Wilhelmsen L, Betteridge J, Birkeland K, Golay A, Heine RJ, Koranyi L, Laakso M, Mokan M, Norkus A, Pirags V, Podar T, Scheen A, Scherbaum W, Schernthaner G, Schmitz O, Skrha J, Smith U, Taton J; PROactive investigators. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial. Lancet 366: 1279-1289, 2005.
-
(2005)
Lancet
, vol.366
, pp. 1279-1289
-
-
Dormandy, J.A.1
Charbonnel, B.2
Eckland, D.J.3
Erdmann, E.4
Massi-Benedetti, M.5
Moules, I.K.6
Skene, A.M.7
Tan, M.H.8
Lefebvre, P.J.9
Murray, G.D.10
Standl, E.11
Wilcox, R.G.12
Wilhelmsen, L.13
Betteridge, J.14
Birkeland, K.15
Golay, A.16
Heine, R.J.17
Koranyi, L.18
Laakso, M.19
Mokan, M.20
Norkus, A.21
Pirags, V.22
Podar, T.23
Scheen, A.24
Scherbaum, W.25
Schernthaner, G.26
Schmitz, O.27
Skrha, J.28
Smith, U.29
Taton, J.30
more..
-
24
-
-
34250357149
-
Differential regulation of thioredoxin and NAD(P)H oxidase by angiotensin II in male and female mice
-
Ebrahimian T, He Y, Schiffrin EL, Touyz RM. Differential regulation of thioredoxin and NAD(P)H oxidase by angiotensin II in male and female mice. J Hypertens 25: 1263-1271, 2007.
-
(2007)
J Hypertens
, vol.25
, pp. 1263-1271
-
-
Ebrahimian, T.1
He, Y.2
Schiffrin, E.L.3
Touyz, R.M.4
-
25
-
-
79955770689
-
Protecting against vascular disease in brain
-
Faraci FM. Protecting against vascular disease in brain. Am J Physiol Heart Circ Physiol 300: H1566-H1582, 2011.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.300
, pp. H1566-H1582
-
-
Faraci, F.M.1
-
26
-
-
33645849538
-
Cerebral vascular effects of angiotensin II: New insights from genetic models
-
Faraci FM, Lamping KG, Modrick ML, Ryan MJ, Sigmund CD, Didion SP. Cerebral vascular effects of angiotensin II: new insights from genetic models. J Cereb Blood Flow Metab 26: 449-455, 2006.
-
(2006)
J Cereb Blood Flow Metab
, vol.26
, pp. 449-455
-
-
Faraci, F.M.1
Lamping, K.G.2
Modrick, M.L.3
Ryan, M.J.4
Sigmund, C.D.5
Didion, S.P.6
-
27
-
-
33744946795
-
Selective cerebral vascular dysfunction in Mn-SOD-deficient mice
-
Faraci FM, Modrick ML, Lynch CM, Didion LA, Fegan PE, Didion SP. Selective cerebral vascular dysfunction in Mn-SOD-deficient mice. J Appl Physiol 100: 2089-2093, 2006.
-
(2006)
J Appl Physiol
, vol.100
, pp. 2089-2093
-
-
Faraci, F.M.1
Modrick, M.L.2
Lynch, C.M.3
Didion, L.A.4
Fegan, P.E.5
Didion, S.P.6
-
28
-
-
0031952267
-
Responses of carotid artery in mice deficient in expression of the gene for endothelial NO synthase
-
Faraci FM, Sigmund CD, Shesely EG, Maeda N, Heistad DD. Responses of carotid artery in mice deficient in expression of the gene for endothelial NO synthase. Am J Physiol Heart Circ Physiol 274: H564-H570, 1998.
-
(1998)
Am J Physiol Heart Circ Physiol
, vol.274
, pp. H564-H570
-
-
Faraci, F.M.1
Sigmund, C.D.2
Shesely, E.G.3
Maeda, N.4
Heistad, D.D.5
-
29
-
-
0030462770
-
The peroxisome proliferator-activated receptors: Ligands and activators
-
Forman BM, Chen J, Evans RM. The peroxisome proliferator-activated receptors: ligands and activators. Ann NY Acad Sci 804: 266-275, 1996.
-
(1996)
Ann NY Acad Sci
, vol.804
, pp. 266-275
-
-
Forman, B.M.1
Chen, J.2
Evans, R.M.3
-
30
-
-
0028972025
-
15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma
-
Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM, Evans RM. 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell 83: 803-812, 1995.
-
(1995)
Cell
, vol.83
, pp. 803-812
-
-
Forman, B.M.1
Tontonoz, P.2
Chen, J.3
Brun, R.P.4
Spiegelman, B.M.5
Evans, R.M.6
-
31
-
-
60749137151
-
NADPH oxidase-dependent signaling in endothelial cells: Role in physiology and pathophysiology
-
Frey RS, Ushio-Fukai M, Malik AB. NADPH oxidase-dependent signaling in endothelial cells: role in physiology and pathophysiology. Antioxid Redox Signal 11: 791-810, 2009.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 791-810
-
-
Frey, R.S.1
Ushio-Fukai, M.2
Malik, A.B.3
-
32
-
-
0036882135
-
Effects of pioglitazone in nondiabetic patients with arterial hypertension: A double-blind, placebo-controlled study
-
Fullert S, Schneider F, Haak E, Rau H, Badenhoop K, Lubben G, Usadel KH, Konrad T. Effects of pioglitazone in nondiabetic patients with arterial hypertension: a double-blind, placebo-controlled study. J Clin Endocrinol Metab 87: 5503-5506, 2002.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 5503-5506
-
-
Fullert, S.1
Schneider, F.2
Haak, E.3
Rau, H.4
Badenhoop, K.5
Lubben, G.6
Usadel, K.H.7
Konrad, T.8
-
33
-
-
77954988618
-
Risk of acute myocardial infarction, stroke, heart failure, and death in elderly Medicare patients treated with rosiglitazone or pioglitazone
-
Graham DJ, Ouellet-Hellstrom R, MaCurdy TE, Ali F, Sholley C, Worrall C, Kelman JA. Risk of acute myocardial infarction, stroke, heart failure, and death in elderly Medicare patients treated with rosiglitazone or pioglitazone. JAMA 304: 411-418, 2010.
-
(2010)
JAMA
, vol.304
, pp. 411-418
-
-
Graham, D.J.1
Ouellet-Hellstrom, R.2
Macurdy, T.E.3
Ali, F.4
Sholley, C.5
Worrall, C.6
Kelman, J.A.7
-
34
-
-
39649100393
-
Interference with PPAR gamma function in smooth muscle causes vascular dysfunction and hypertension
-
Halabi CM, Beyer AM, de Lange WJ, Keen HL, Baumbach GL, Faraci FM, Sigmund CD. Interference with PPAR gamma function in smooth muscle causes vascular dysfunction and hypertension. Cell Metab 7: 215-226, 2008.
-
(2008)
Cell Metab
, vol.7
, pp. 215-226
-
-
Halabi, C.M.1
Beyer, A.M.2
De Lange, W.J.3
Keen, H.L.4
Baumbach, G.L.5
Faraci, F.M.6
Sigmund, C.D.7
-
35
-
-
0035074065
-
Carotid plaque and intima-media thickness assessed by b-mode ultrasonography in subjects ranging from young adults to centenarians
-
Homma S, Hirose N, Ishida H, Ishii T, Araki G. Carotid plaque and intima-media thickness assessed by b-mode ultrasonography in subjects ranging from young adults to centenarians. Stroke 32: 830-835, 2001.
-
(2001)
Stroke
, vol.32
, pp. 830-835
-
-
Homma, S.1
Hirose, N.2
Ishida, H.3
Ishii, T.4
Araki, G.5
-
36
-
-
0035180319
-
The ligands/activators for peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma increase Cu2,Zn2 -superoxide dismutase and decrease p22phox message expressions in primary endothelial cells
-
Inoue I, Goto S, Matsunaga T, Nakajima T, Awata T, Hokari S, Komoda T, Katayama S. The ligands/activators for peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma increase Cu2,Zn2 -superoxide dismutase and decrease p22phox message expressions in primary endothelial cells. Metabolism 50: 3-11, 2001.
-
(2001)
Metabolism
, vol.50
, pp. 3-11
-
-
Inoue, I.1
Goto, S.2
Matsunaga, T.3
Nakajima, T.4
Awata, T.5
Hokari, S.6
Komoda, T.7
Katayama, S.8
-
37
-
-
61749083559
-
PPARgamma in the endothelium regulates metabolic responses to high-fat diet in mice
-
Kanda T, Brown JD, Orasanu G, Vogel S, Gonzalez FJ, Sartoretto J, Michel T, Plutzky J. PPARgamma in the endothelium regulates metabolic responses to high-fat diet in mice. J Clin Invest 119: 110-124, 2009.
-
(2009)
J Clin Invest
, vol.119
, pp. 110-124
-
-
Kanda, T.1
Brown, J.D.2
Orasanu, G.3
Vogel, S.4
Gonzalez, F.J.5
Sartoretto, J.6
Michel, T.7
Plutzky, J.8
-
38
-
-
84870039725
-
PPAR gamma regulates resistance vessel tone through a mechanism involving RGS5-mediated control of protein kinase C and BKCa channel activity
-
Ketsawatsomkron P, Lorca RA, Keen HL, Weatherford ET, Liu X, Pelham CJ, Grobe JL, Faraci FM, England SK, Sigmund CD. PPAR gamma regulates resistance vessel tone through a mechanism involving RGS5-mediated control of protein kinase C and BKCa channel activity. Circ Res 111: 1446-1458, 2012.
-
(2012)
Circ Res
, vol.111
, pp. 1446-1458
-
-
Ketsawatsomkron, P.1
Lorca, R.A.2
Keen, H.L.3
Weatherford, E.T.4
Liu, X.5
Pelham, C.J.6
Grobe, J.L.7
Faraci, F.M.8
England, S.K.9
Sigmund, C.D.10
-
39
-
-
70350433697
-
Disruption of endothelial peroxisome proliferator-activated receptor-gamma reduces vascular nitric oxide production
-
Kleinhenz JM, Kleinhenz DJ, You S, Ritzenthaler JD, Hansen JM, Archer DR, Sutliff RL, Hart CM. Disruption of endothelial peroxisome proliferator-activated receptor-gamma reduces vascular nitric oxide production. Am J Physiol Heart Circ Physiol 297: H1647-H1654, 2009.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
, pp. H1647-H1654
-
-
Kleinhenz, J.M.1
Kleinhenz, D.J.2
You, S.3
Ritzenthaler, J.D.4
Hansen, J.M.5
Archer, D.R.6
Sutliff, R.L.7
Hart, C.M.8
-
40
-
-
79955586590
-
Cellular senescence, vascular disease, and aging: Part 2 of a 2-part review: Clinical vascular disease in the elderly
-
Kovacic JC, Moreno P, Nabel EG, Hachinski V, Fuster V. Cellular senescence, vascular disease, and aging: part 2 of a 2-part review: clinical vascular disease in the elderly. Circulation 123: 1900-1910, 2011.
-
(2011)
Circulation
, vol.123
, pp. 1900-1910
-
-
Kovacic, J.C.1
Moreno, P.2
Nabel, E.G.3
Hachinski, V.4
Fuster, V.5
-
41
-
-
84881022773
-
Peroxisome proliferator-activated receptor gamma, coactivator 1alpha deletion induces angiotensin II-associated vascular dysfunction by increasing mitochondrial oxidative stress and vascular inflammation
-
Kröller-Schön S, Jansen T, Schuler A, Oelze M, Wenzel P, Hausding M, Kerahrodi JG, Beisele M, Lackner KJ, Daiber A, Münzel T, Schulz E. Peroxisome proliferator-activated receptor gamma, coactivator 1alpha deletion induces angiotensin II-associated vascular dysfunction by increasing mitochondrial oxidative stress and vascular inflammation. Arterioscler Thromb Vasc Biol 33: 1928-1935, 2013.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 1928-1935
-
-
Kröller-Schön, S.1
Jansen, T.2
Schuler, A.3
Oelze, M.4
Wenzel, P.5
Hausding, M.6
Kerahrodi, J.G.7
Beisele, M.8
Lackner, K.J.9
Daiber, A.10
Münzel, T.11
Schulz, E.12
-
42
-
-
0032929229
-
Agonist-specific impairment of coronary vascular function in genetically altered, hyperlipidemic mice
-
Lamping KG, Nuno DW, Chappell DA, Faraci FM. Agonist-specific impairment of coronary vascular function in genetically altered, hyperlipidemic mice. Am J Physiol Regul Integr Comp Physiol 276: R1023-R1029, 1999.
-
(1999)
Am J Physiol Regul Integr Comp Physiol
, vol.276
, pp. R1023-R1029
-
-
Lamping, K.G.1
Nuno, D.W.2
Chappell, D.A.3
Faraci, F.M.4
-
43
-
-
0035844030
-
Novel gp91(Phox) homologues in vascular smooth muscle cells: Nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways
-
Lassegue B, Sorescu D, Szocs K, Yin Q, Akers M, Zhang Y, Grant SL, Lambeth JD, Griendling KK. Novel gp91(phox) homologues in vascular smooth muscle cells: nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways. Circ Res 88: 888-894, 2001.
-
(2001)
Circ Res
, vol.88
, pp. 888-894
-
-
Lassegue, B.1
Sorescu, D.2
Szocs, K.3
Yin, Q.4
Akers, M.5
Zhang, Y.6
Grant, S.L.7
Lambeth, J.D.8
Griendling, K.K.9
-
44
-
-
0034696412
-
Expression and function of PPARgamma in rat and human vascular smooth muscle cells
-
Law RE, Goetze S, Xi XP, Jackson S, Kawano Y, Demer L, Fishbein MC, Meehan WP, Hsueh WA. Expression and function of PPARgamma in rat and human vascular smooth muscle cells. Circulation 101: 1311-1318, 2000.
-
(2000)
Circulation
, vol.101
, pp. 1311-1318
-
-
Law, R.E.1
Goetze, S.2
Xi, X.P.3
Jackson, S.4
Kawano, Y.5
Demer, L.6
Fishbein, M.C.7
Meehan, W.P.8
Hsueh, W.A.9
-
45
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
-
Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem 270: 12953-12956, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkison, W.O.4
Willson, T.M.5
Kliewer, S.A.6
-
46
-
-
34447523496
-
NADPH oxidase-derived superoxide anion mediates angiotensin II-enhanced carotid body chemo-receptor sensitivity in heart failure rabbits
-
Li YL, Gao L, Zucker IH, Schultz HD. NADPH oxidase-derived superoxide anion mediates angiotensin II-enhanced carotid body chemo-receptor sensitivity in heart failure rabbits. Cardiovasc Res 75: 546-554, 2007.
-
(2007)
Cardiovasc Res
, vol.75
, pp. 546-554
-
-
Li, Y.L.1
Gao, L.2
Zucker, I.H.3
Schultz, H.D.4
-
47
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2-delta delta C(T) method
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2-delta delta C(T) method. Methods 25: 402-408, 2001.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
48
-
-
84874251583
-
Protective role of vascular smooth muscle cell PPARgamma in angiotensin II-induced vascular disease
-
Marchesi C, Rehman A, Rautureau Y, Kasal DA, Briet M, Leibowitz A, Simeone SM, Ebrahimian T, Neves MF, Offermanns S, Gonzalez FJ, Paradis P, Schiffrin EL. Protective role of vascular smooth muscle cell PPARgamma in angiotensin II-induced vascular disease. Cardiovasc Res 97: 562-570, 2013.
-
(2013)
Cardiovasc Res
, vol.97
, pp. 562-570
-
-
Marchesi, C.1
Rehman, A.2
Rautureau, Y.3
Kasal, D.A.4
Briet, M.5
Leibowitz, A.6
Simeone, S.M.7
Ebrahimian, T.8
Neves, M.F.9
Offermanns, S.10
Gonzalez, F.J.11
Paradis, P.12
Schiffrin, E.L.13
-
49
-
-
0032587328
-
PPARgamma activation in human endothelial cells increases plasminogen activator inhibitor type-1 expression: PPARgamma as a potential mediator in vascular disease
-
Marx N, Bourcier T, Sukhova GK, Libby P, Plutzky J. PPARgamma activation in human endothelial cells increases plasminogen activator inhibitor type-1 expression: PPARgamma as a potential mediator in vascular disease. Arterioscler Thromb Vasc Biol 19: 546-551, 1999.
-
(1999)
Arterioscler Thromb Vasc Biol
, vol.19
, pp. 546-551
-
-
Marx, N.1
Bourcier, T.2
Sukhova, G.K.3
Libby, P.4
Plutzky, J.5
-
50
-
-
0034660182
-
Peroxisome proliferator-activated receptor-gamma activators inhibit IFN-gamma-induced expression of the T cell-active CXC chemokines IP-10, Mig, and I-TAC in human endothelial cells
-
Marx N, Mach F, Sauty A, Leung JH, Sarafi MN, Ransohoff RM, Libby P, Plutzky J, Luster AD. Peroxisome proliferator-activated receptor-gamma activators inhibit IFN-gamma-induced expression of the T cell-active CXC chemokines IP-10, Mig, and I-TAC in human endothelial cells. J Immunol 164: 6503-6508, 2000.
-
(2000)
J Immunol
, vol.164
, pp. 6503-6508
-
-
Marx, N.1
Mach, F.2
Sauty, A.3
Leung, J.H.4
Sarafi, M.N.5
Ransohoff, R.M.6
Libby, P.7
Plutzky, J.8
Luster, A.D.9
-
51
-
-
0344333464
-
Peroxisome proliferator-activated receptor gamma activators inhibit gene expression and migration in human vascular smooth muscle cells
-
Marx N, Schonbeck U, Lazar MA, Libby P, Plutzky J. Peroxisome proliferator-activated receptor gamma activators inhibit gene expression and migration in human vascular smooth muscle cells. Circ Res 83: 1097-1103, 1998.
-
(1998)
Circ Res
, vol.83
, pp. 1097-1103
-
-
Marx, N.1
Schonbeck, U.2
Lazar, M.A.3
Libby, P.4
Plutzky, J.5
-
52
-
-
27444441677
-
Nox1 is involved in angiotensin II-mediated hypertension: A study in Nox1-deficient mice
-
Matsuno K, Yamada H, Iwata K, Jin D, Katsuyama M, Matsuki M, Takai S, Yamanishi K, Miyazaki M, Matsubara H, Yabe-Nishimura C. Nox1 is involved in angiotensin II-mediated hypertension: a study in Nox1-deficient mice. Circulation 112: 2677-2685, 2005.
-
(2005)
Circulation
, vol.112
, pp. 2677-2685
-
-
Matsuno, K.1
Yamada, H.2
Iwata, K.3
Jin, D.4
Katsuyama, M.5
Matsuki, M.6
Takai, S.7
Yamanishi, K.8
Miyazaki, M.9
Matsubara, H.10
Yabe-Nishimura, C.11
-
53
-
-
0025883342
-
Nitric oxide: Physiology, patho-physiology, and pharmacology
-
Moncada S, Palmer RM, Higgs EA. Nitric oxide: physiology, patho-physiology, and pharmacology. Pharmacol Rev 43: 109-142, 1991.
-
(1991)
Pharmacol Rev
, vol.43
, pp. 109-142
-
-
Moncada, S.1
Palmer, R.M.2
Higgs, E.A.3
-
54
-
-
79959704368
-
Role of endothelial Nox2 NADPH oxidase in angiotensin II-induced hypertension and vasomotor dysfunction
-
Murdoch CE, Alom-Ruiz SP, Wang M, Zhang M, Walker S, Yu B, Brewer A, Shah AM. Role of endothelial Nox2 NADPH oxidase in angiotensin II-induced hypertension and vasomotor dysfunction. Basic Res Cardiol 106: 527-538, 2011.
-
(2011)
Basic Res Cardiol
, vol.106
, pp. 527-538
-
-
Murdoch, C.E.1
Alom-Ruiz, S.P.2
Wang, M.3
Zhang, M.4
Walker, S.5
Yu, B.6
Brewer, A.7
Shah, A.M.8
-
55
-
-
17044430286
-
PPARgamma in endothelial cells influences high fat diet-induced hypertension
-
Nicol CJ, Adachi M, Akiyama TE, Gonzalez FJ. PPARgamma in endothelial cells influences high fat diet-induced hypertension. Am J Hypertens 18: 549-556, 2005.
-
(2005)
Am J Hypertens
, vol.18
, pp. 549-556
-
-
Nicol, C.J.1
Adachi, M.2
Akiyama, T.E.3
Gonzalez, F.J.4
-
56
-
-
41649084422
-
Comparison of pioglitazone vs glimepiride on progression of coronary atherosclerosis in patients with type 2 diabetes: The PERISCOPE randomized controlled trial
-
Nissen SE, Nicholls SJ, Wolski K, Nesto R, Kupfer S, Perez A, Jure H, De Larochelliere R, Staniloae CS, Mavromatis K, Saw J, Hu B, Lincoff AM, Tuzcu EM; PERISCOPE Investigators. Comparison of pioglitazone vs glimepiride on progression of coronary atherosclerosis in patients with type 2 diabetes: the PERISCOPE randomized controlled trial. JAMA 299: 1561-1573, 2008.
-
(2008)
JAMA
, vol.299
, pp. 1561-1573
-
-
Nissen, S.E.1
Nicholls, S.J.2
Wolski, K.3
Nesto, R.4
Kupfer, S.5
Perez, A.6
Jure, H.7
De Larochelliere, R.8
Staniloae, C.S.9
Mavromatis, K.10
Saw, J.11
Hu, B.12
Lincoff, A.M.13
Tuzcu, E.M.14
Investigators, P.15
-
57
-
-
84867084491
-
Cullin-3 regulates vascular smooth muscle function and arterial blood pressure via PPARgamma and RhoA/Rho-kinase
-
Pelham CJ, Ketsawatsomkron P, Groh S, Grobe JL, de Lange WJ, Ibeawuchi SR, Keen HL, Weatherford ET, Faraci FM, Sigmund CD. Cullin-3 regulates vascular smooth muscle function and arterial blood pressure via PPARgamma and RhoA/Rho-kinase. Cell Metab 16: 462-472, 2012.
-
(2012)
Cell Metab
, vol.16
, pp. 462-472
-
-
Pelham, C.J.1
Ketsawatsomkron, P.2
Groh, S.3
Grobe, J.L.4
De Lange, W.J.5
Ibeawuchi, S.R.6
Keen, H.L.7
Weatherford, E.T.8
Faraci, F.M.9
Sigmund, C.D.10
-
58
-
-
0038220757
-
Rosigli- tazone improves insulin sensitivity and lowers blood pressure in hypertensive patients
-
Raji A, Seely EW, Bekins SA, Williams GH, Simonson DC. Rosigli- tazone improves insulin sensitivity and lowers blood pressure in hypertensive patients. Diabetes Care 26: 172-178, 2003.
-
(2003)
Diabetes Care
, vol.26
, pp. 172-178
-
-
Raji, A.1
Seely, E.W.2
Bekins, S.A.3
Williams, G.H.4
Simonson, D.C.5
-
59
-
-
1442288375
-
PPAR- (Gamma) agonist rosiglitazone improves vascular function and lowers blood pressure in hypertensive transgenic mice
-
Ryan MJ, Didion SP, Mathur S, Faraci FM, Sigmund CD. PPAR- (gamma) agonist rosiglitazone improves vascular function and lowers blood pressure in hypertensive transgenic mice. Hypertension 43: 661-666, 2004.
-
(2004)
Hypertension
, vol.43
, pp. 661-666
-
-
Ryan, M.J.1
Didion, S.P.2
Mathur, S.3
Faraci, F.M.4
Sigmund, C.D.5
-
60
-
-
0034724305
-
Expression of angiotensin II and interleukin 6 in human coronary atherosclerotic plaques: Potential implications for inflammation and plaque instability
-
Schieffer B, Schieffer E, Hilfiker-Kleiner D, Hilfiker A, Kovanen PT, Kaartinen M, Nussberger J, Harringer W, Drexler H. Expression of angiotensin II and interleukin 6 in human coronary atherosclerotic plaques: potential implications for inflammation and plaque instability. Circulation 101: 1372-1378, 2000.
-
(2000)
Circulation
, vol.101
, pp. 1372-1378
-
-
Schieffer, B.1
Schieffer, E.2
Hilfiker-Kleiner, D.3
Hilfiker, A.4
Kovanen, P.T.5
Kaartinen, M.6
Nussberger, J.7
Harringer, W.8
Drexler, H.9
-
61
-
-
84862776938
-
Nox4 is a protective reactive oxygen species generating vascular NADPH oxidase
-
Schroder K, Zhang M, Benkhoff S, Mieth A, Pliquett R, Kosowski J, Kruse C, Luedike P, Michaelis UR, Weissmann N, Dimmeler S, Shah AM, Brandes RP. Nox4 is a protective reactive oxygen species generating vascular NADPH oxidase. Circ Res 110: 1217-1225, 2012.
-
(2012)
Circ Res
, vol.110
, pp. 1217-1225
-
-
Schroder, K.1
Zhang, M.2
Benkhoff, S.3
Mieth, A.4
Pliquett, R.5
Kosowski, J.6
Kruse, C.7
Luedike, P.8
Michaelis, U.R.9
Weissmann, N.10
Dimmeler, S.11
Shah, A.M.12
Brandes, R.P.13
-
62
-
-
0034633847
-
Peroxisome proliferator-activated receptor gamma activators downregulate angiotensin II type 1 receptor in vascular smooth muscle cells
-
Takeda K, Ichiki T, Tokunou T, Funakoshi Y, Iino N, Hirano K, Kanaide H, Takeshita A. Peroxisome proliferator-activated receptor gamma activators downregulate angiotensin II type 1 receptor in vascular smooth muscle cells. Circulation 102: 1834-1839, 2000.
-
(2000)
Circulation
, vol.102
, pp. 1834-1839
-
-
Takeda, K.1
Ichiki, T.2
Tokunou, T.3
Funakoshi, Y.4
Iino, N.5
Hirano, K.6
Kanaide, H.7
Takeshita, A.8
-
63
-
-
0037076798
-
Expression of a functionally active gp91phox-containing neutrophil-type NAD(P)H oxidase in smooth muscle cells from human resistance arteries: Regulation by angiotensin II
-
Touyz RM, Chen X, Tabet F, Yao G, He G, Quinn MT, Pagano PJ, Schiffrin EL. Expression of a functionally active gp91phox-containing neutrophil-type NAD(P)H oxidase in smooth muscle cells from human resistance arteries: regulation by angiotensin II. Circ Res 90: 1205-1213, 2002.
-
(2002)
Circ Res
, vol.90
, pp. 1205-1213
-
-
Touyz, R.M.1
Chen, X.2
Tabet, F.3
Yao, G.4
He, G.5
Quinn, M.T.6
Pagano, P.J.7
Schiffrin, E.L.8
-
64
-
-
0026097787
-
Hypertension and vascular disease
-
Vanhoutte PM. Serotonin, hypertension and vascular disease. Neth J Med 38: 35-42, 1991.
-
(1991)
Neth J Med
, vol.38
, pp. 35-42
-
-
Serotonin, V.P.1
-
65
-
-
0032993428
-
The thiazolidinedione rosiglitazone (BRL-49653) lowers blood pressure and protects against impairment of endothelial function in Zucker fatty rats
-
Walker AB, Chattington PD, Buckingham RE, Williams G. The thiazolidinedione rosiglitazone (BRL-49653) lowers blood pressure and protects against impairment of endothelial function in Zucker fatty rats. Diabetes 48: 1448-1453, 1999.
-
(1999)
Diabetes
, vol.48
, pp. 1448-1453
-
-
Walker, A.B.1
Chattington, P.D.2
Buckingham, R.E.3
Williams, G.4
|