Early exposure to bio-contaminants and asthma up to 10 years of age: Results of the HITEA study

European Respiratory Journal

Volumn 45, Issue 2, 2015, Pages 328-337

  Tischer, Christina ^a   Casas, Lidia ^b,c,d,e   Wouters, Inge M ^f   Doekes, Gert ^f   Garcia Esteban, Raquel ^c,d,e   Gehring, Ulrike ^f   Hyvärinen, Anne ^g   Oldenwening, Marieke ^f   Kerkhof, Marjan ^h   Sunyer, Jordi ^c,d,e,i   Standl, Marie ^a   Thiering, Elisabeth ^a,j   Torrent, Maties ^k   Heinrich, Joachim ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c CENTRE FOR RESEARCH IN ENVIRONMENTAL EPIDEMIOLOGY CREAL   (Spain)

^d CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

^e HOSPITAL DEL MAR   (Spain)

^f UTRECHT UNIVERSITY   (Netherlands)

^g NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^h UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

ⁱ UNIVERSITAT POMPEU FABRA   (Spain)

^j LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^k IB SALUT ^*  (Spain)

more..

Author keywords

[No Author keywords available]

Indexed keywords

(1,3) BETA DEXTRO GLUCAN; ENDOTOXIN; GLUCAN; IMMUNOGLOBULIN E; POLYSACCHARIDE; UNCLASSIFIED DRUG; AIR POLLUTANT; ALLERGEN; BETA GLUCAN; BETA-1,3-D-GLUCAN; DUST;

ARTICLE; ASTHMA; CHILD; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISEASE ASSOCIATION; DUST; ENVIRONMENTAL EXPOSURE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL INFORMATION; PRESCHOOL CHILD; PROSPECTIVE STUDY; SCHOOL CHILD; SUBURBAN AREA; ADVERSE EFFECTS; AIR POLLUTANT; ANALYSIS; CHEMISTRY; EUROPE; GEOGRAPHY; HYPERSENSITIVITY; IMMEDIATE TYPE HYPERSENSITIVITY; IMMUNOLOGY; NEWBORN; QUESTIONNAIRE; STATISTICAL MODEL; URBAN POPULATION;

AIR POLLUTANTS; ALLERGENS; ASTHMA; BETA-GLUCANS; CHILD; DUST; ENDOTOXINS; ENVIRONMENTAL EXPOSURE; EUROPE; FEMALE; GEOGRAPHY; HUMANS; HYPERSENSITIVITY; HYPERSENSITIVITY, IMMEDIATE; IMMUNOGLOBULIN E; INFANT, NEWBORN; LOGISTIC MODELS; MALE; POLYSACCHARIDES; PROSPECTIVE STUDIES; SURVEYS AND QUESTIONNAIRES; URBAN POPULATION;

EID: 84961289613     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00060214     Document Type: Article

References (38)

1. Prescott SL, Macaubas C, Smallacombe T, et al. Development of allergen-specific T-cell memory in atopic and normal children. Lancet 1999;353:196-200.
2. Von Mutius E. Epidemiology of allergic diseases. In: Leung DY, Sampsom, HA, Geha R, et al., eds. Pediatric Allergy: Principles and Practice. St Louis, Mosby, 2010; pp. 1-8.
3. Schram-Bijkerk D, Doekes G, Douwes J, et al. Bacterial and fungal agents in house dust and wheeze in children: the PARSIFAL study. Clin Exp Allergy 2005;35:1272-1278.
4. van Strien RT, Engel R, Holst O, et al. Microbial exposure of rural school children, as assessed by levels of N-acetyl-muramic acid in mattress dust, and its association with respiratory health. J Allergy Clin Immunol 2004;113:860-867.
5. Karvonen AM, Hyvarinen A, Gehring U, et al. Exposure to microbial agents in house dust and wheezing, atopic dermatitis and atopic sensitization in early childhood: a birth cohort study in rural areas. Clin Exp Allergy 2012;42:1246-1256.
6. Braun-Fahrlander C, Riedler J, Herz U, et al. Environmental exposure to endotoxin and its relation to asthma in school-age children. N Engl J Med 2002;347:869-877.
7. Eduard W, Omenaas E, Bakke PS, et al. Atopic and non-atopic asthma in a farming and a general population. Am J Ind Med 2004;46:396-399.
8. Gehring U, Bolte G, Borte M, et al. Exposure to endotoxin decreases the risk of atopic eczema in infancy: a cohort study. J Allergy Clin Immunol 2001;108:847-854.
9. Iossifova YY, Reponen T, Bernstein DI, et al. House dust (1-3)-β-D-glucan and wheezing in infants. Allergy 2007;62:504-513.
10. Douwes J, van Strien R, Doekes G, et al. Does early indoor microbial exposure reduce the risk of asthma? The Prevention and Incidence of Asthma and Mite Allergy birth cohort study. J Allergy Clin Immunol 2006;117:1067-1073.
11. Celedon JC, Milton DK, Ramsey CD, et al. Exposure to dust mite allergen and endotoxin in early life and asthma and atopy in childhood. J Allergy Clin Immunol 2007;120:144-149.
12. Casas L, Tischer C, Wouters IM, et al. Early life microbial exposure and fractional exhaled nitric oxide in school-age children: a prospective birth cohort study. Environ Health 2013;12:103.
13. Park JH, Gold DR, Spiegelman DL, et al. House dust endotoxin and wheeze in the first year of life. Am J Respir Crit Care Med 2001;163:322-328.
14. Litonjua AA, Milton DK, Celedon JC, et al. A longitudinal analysis of wheezing in young children: the independent effects of early life exposure to house dust endotoxin, allergens, and pets. J Allergy Clin Immunol 2002;110:736-742.
15. Bolte G, Bischof W, Borte M, et al. Early endotoxin exposure and atopy development in infants: results of a birth cohort study. Clin Exp Allergy 2003;33:770-776.
16. Torrent M, Sunyer J, Garcia R, et al. Early-life allergen exposure and atopy, asthma, and wheeze up to 6 years of age. Am J Respir Crit Care Med 2007;176:446-453.
17. Wijga AH, Kerkhof M, Gehring U, et al. Cohort profile: the Prevention and Incidence of Asthma and Mite Allergy (PIAMA) birth cohort. Int J Epidemiol 2014;43:527-535.
18. Heinrich J, Bolte G, Hölscher B, et al. Allergens and endotoxin on mothers' mattresses and total immunoglobulin E in cord blood of neonates. Eur Respir J 2002;20:617-623.
19. Casas L, Tischer C, Wouters IM, et al. Endotoxin, extracellular polysaccharides, and β (1-3)-glucan concentrations in dust and their determinants in four European birth cohorts: results from the HITEA project. Indoor Air 2013;23:208-218.
20. Asher MI, Keil U, Anderson HR, et al. International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. Eur Respir J 1995;8:483-491.
21. Lodrup Carlsen KC, Haland G, Devulapalli CS, et al. Asthma in every fifth child in Oslo, Norway: a 10-year follow up of a birth cohort study. Allergy 2006;61:454-460.
22. Lodrup Carlsen KC, Roll S, Carlsen KH, et al. Does pet ownership in infancy lead to asthma or allergy at school age? Pooled analysis of individual participant data from 11 European birth cohorts. PLoS One 2012;7:e43214.
23. Ryan PH, Bernstein DI, Lockey J, et al. Exposure to traffic-related particles and endotoxin during infancy is associated with wheezing at age 3 years. Am J Respir Crit Care Med 2009;180:1068-1075.
24. Gern JE. Viral respiratory infection and the link to asthma. Pediatr Infect Dis J 2008;27:Suppl. 10, S97-S103.
25. Guilbert TW, Gern, JE, Lemanske RF. Infections and asthma. In: Leung DY, Sampsom, HA, Geha R, et al., eds. Pediatric Allergy: Principles and Practice. St Louis, Mosby, 2010; pp. 363-376.
26. Frankel M, Timm M, Hansen EW, et al. Comparison of sampling methods for the assessment of indoor microbial exposure. Indoor Air 2012;22:405-414.
27. Thorne PS, Cohn RD, Mav D, et al. Predictors of endotoxin levels in U. S. housing. Environ Health Perspect 2009;117:763-771.
28. Ege MJ, Mayer M, Normand AC, et al. Exposure to environmental microorganisms and childhood asthma. N Engl J Med 2011;364:701-709.
29. Ege MJ, Mayer M, Schwaiger K, et al. Environmental bacteria and childhood asthma. Allergy 2012;67:1565-1571.
30. Tischer CG, Heinrich J. Exposure assessment of residential mould, fungi and microbial components in relation to children's health: achievements and challenges. Int J Hyg Environ Health 2013;216:109-114.
31. Caudri D, Savenije OE, Smit HA, et al. Perinatal risk factors for wheezing phenotypes in the first 8 years of life. Clin Exp Allergy 2013;43:1395-1405.
32. Institue of Medicine. Damp Indoor Spaces and Health. Washington, D. C., National Academy Press, 2004.
33. Tischer C, Gehring U, Chen CM, et al. Respiratory health in children, and indoor exposure to (1, 3)-β-D-glucan, EPS mould components and endotoxin. Eur Respir J 2011;37:1050-1059.
34. Heinrich J, Holscher B, Douwes J, et al. Reproducibility of allergen, endotoxin and fungi measurements in the indoor environment. J Expo Anal Environ Epidemiol 2003;13:152-160.
35. Sordillo JE, Hoffman EB, Celedon JC, et al. Multiple microbial exposures in the home may protect against asthma or allergy in childhood. Clin Exp Allergy 2010;40:902-910.
36. Jacobs JH, Krop EJ, Borras-Santos A, et al. Endotoxin levels in settled airborne dust in European schools: the HITEA school study. Indoor Air 2014;24:148-157.
37. Jacobs JH, Krop EJ, de Wind S, et al. Endotoxin levels in homes and classrooms of Dutch school children and respiratory health. Eur Respir J 2013;42:314-322.
38. Sheehan WJ, Hoffman EB, Fu C, et al. Endotoxin exposure in inner-city schools and homes of children with asthma. Ann Allergy Asthma Immunol 2012;108:418-422.