Endotoxin, extracellular polysaccharides, and β(1-3)-glucan concentrations in dust and their determinants in four European birth cohorts: Results from the HITEA project

Indoor Air

Volumn 23, Issue 3, 2013, Pages 208-218

  Casas, Lidia ^a,b,c   Tischer, C ^d   Wouters, I M ^e   Valkonen, M ^f   Gehring, U ^e   Doekes, G ^e   Torrent, M ^g   Pekkanen, J ^f,h   Garcia Esteban, R ^a,b,c   Hyvarinen A ^f   Heinrich, J ^d   Sunyer, J ^a,b,c,i  

^a CENTRE FOR RESEARCH IN ENVIRONMENTAL EPIDEMIOLOGY CREAL   (Spain)

^b INST MUNIC D INVESTIGACIO MEDICA   (Spain)

^c CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

^e UTRECHT UNIVERSITY   (Netherlands)

^f NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^g IB SALUT   (Spain)

^h UNIVERSITY OF EASTERN FINLAND   (Finland)

ⁱ UNIVERSITAT POMPEU FABRA   (Spain)

Author keywords

Cohort studies; Endotoxin; Extracellular polysaccharide; Indoor; Microbial agents; (1 3) Glucan

Indexed keywords

POLYSACCHARIDES; POPULATION STATISTICS;

COHORT STUDIES; EARLIEST LIFE; ENDOTOXIN; EXTRACELLULAR POLYSACCHARIDES; GLUCANS; INDOOR; LIVING ROOM; MICROBIAL AGENT; NETHERLANDS; Β(1-3)-GLUCAN;

DUST;

CANIS FAMILIARIS;

EID: 84876708823     PISSN: 09056947     EISSN: 16000668     Source Type: Journal    
DOI: 10.1111/ina.12017     Document Type: Article

References (28)

1. Brunekreef, B., Smit, J., de Jongste, J., Neijens, H., Gerritsen, J., Postma, D., Aalberse, R., Koopman, L., Kerkhof, M., Wilga, A. and van Strien, R. (2002) The prevention and incidence of asthma and mite allergy (PIAMA) birth cohort study: design and first results, Pediatr. Allergy Immunol., 13(Suppl 15), 55-60.
2. Celedón, J.C., Milton, D.K., Ramsey, C.D., Litonjua, A.A., Ryan, L., Platts-Mills, T.A.E. and Gold, D.R. (2007) Exposure to dust mite allergen and endotoxin in early life and asthma and atopy in childhood, J. Allergy Clin. Immunol., 120, 144-149.
3. Chen, C.-M., Thiering, E., Doekes, G., Zock, J.-P., Bakolis, I., Norbäck, D., Sunyer, J., Villani, S., Verlato, G., Täubel, M., Jarvis, D. and Heinrich, J. (2012) Geographical variation and the determinants of domestic endotoxin levels in mattress dust in Europe, Indoor Air, 22, 24-32.
4. Douwes, J., Versloot, P., Hollander, A., Heederik, D. and Doekes, G. (1995) Influence of various dust sampling and extraction methods on the measurement of airborne endotoxin, Appl. Environ. Microbiol., 61, 1763-1769.
5. Douwes, J., van der Sluis, B., Doekes, G., van Leusden, F., Wijnands, L., van Strien, R., Verhoeff, A. and Brunekreef, B. (1999) Fungal extracellular polysaccharides in house dust as a marker for exposure to fungi: relations with culturable fungi, reported home dampness, and respiratory symptoms, J. Allergy Clin. Immunol., 103, 494-500.
6. Douwes, J., Siebers, R., Wouters, I., Doekes, G., Fitzharris, P. and Crane, J. (2006a) Endotoxin, (1 -> 3)-beta-d-glucans and fungal extra-cellular polysaccharides in New Zealand homes: a pilot study, Ann. Agric. Environ. Med., 13, 361-365.
7. Douwes, J., van Strien, R., Doekes, G., Smit, J., Kerkhof, M., Gerritsen, J., Postma, D., de Jongste, J., Travier, N. and Brunekreef, B. (2006b) Does early indoor microbial exposure reduce the risk of asthma? The Prevention and Incidence of Asthma and Mite Allergy birth cohort study, J. Allergy Clin. Immunol., 117, 1067-1073.
8. Fahlbusch, B., Koch, A., Douwes, J., Bischof, W., Gehring, U., Richter, K., Wichmann, H.-E. and Heinrich, J. (2003) The effect of storage on allergen and microbial agent levels in frozen house dust, Allergy, 58, 150-153.
9. Gehring, U., Douwes, J., Doekes, G., Koch, A., Bischof, W., Fahlbusch, B., Richter, K., Wichmann, H.E. and Heinrich, J. (2001) Beta(1->3)-glucan in house dust of German homes: housing characteristics, occupant behavior, and relations with endotoxins, allergens, and molds, Environ. Health Perspect., 109, 139-144.
10. Gehring, U., Bischof, W., Borte, M., Herbarth, O., Wichmann, H.-E. and Heinrich, J. (2004) Levels and predictors of endotoxin in mattress dust samples from East and West German homes, Indoor Air, 14, 284-292.
11. Gehring, U., Heinrich, J., Hoek, G., Giovannangelo, M., Nordling, E., Bellander, T., Gerritsen, J., de Jongste, J.C., Smit, H.A., Wichmann, H.-E., Wickman, M. and Brunekreef, B. (2007) Bacteria and mould components in house dust and children's allergic sensitisation, Eur. Respir. J., 29, 1144-1153.
12. Gehring, U., Strikwold, M., Schram-Bijkerk, D., Weinmayr, G., Genuneit, J., Nagel, G., Wickens, K., Siebers, R., Crane, J., Doekes, G., Di Domenicantonio, R., Nilsson, L., Priftanji, A., Sandin, A., El-Sharif, N., Strachan, D., van Hage, M., von Mutius, E. and Brunekreef, B. (2008) Asthma and allergic symptoms in relation to house dust endotoxin: Phase Two of the International Study on Asthma and Allergies in Childhood (ISAAC II), Clin. Exp. Allergy, 38, 1911-1920.
13. Gereda, J.E., Leung, D.Y., Thatayatikom, A., Streib, J.E., Price, M.R., Klinnert, M.D. and Liu, A.H. (2000) Relation between house-dust endotoxin exposure, type 1 T-cell development, and allergen sensitisation in infants at high risk of asthma, Lancet, 355, 1680-1683.
14. Gereda, J.E., Klinnert, M.D., Price, M.R., Leung, D.Y. and Liu, A.H. (2001) Metropolitan home living conditions associated with indoor endotoxin levels, J. Allergy Clin. Immunol., 107, 790-796.
15. Giovannangelo, M., Gehring, U., Nordling, E., Oldenwening, M., Terpstra, G., Bellander, T., Hoek, G., Heinrich, J. and Brunekreef, B. (2007a) Determinants of house dust endotoxin in three European countries - the AIRALLERG study, Indoor Air, 17, 70-79.
16. Giovannangelo, M., Nordling, E., Gehring, U., Oldenwening, M., Bellander, T., Heinrich, J., Hoek, G. and Brunekreef, B. (2007b) Variation of biocontaminant levels within and between homes-the AIRALLERG study, J. Eposure Sci. Environ. Epidemiol., 17, 134-140.
17. Giovannangelo, M.E.C.A., Gehring, U., Nordling, E., Oldenwening, M., van Rijswijk, K., de Wind, S., Hoek, G., Heinrich, J., Bellander, T. and Brunekreef, B. (2007c) Levels and determinants of beta(1->3)-glucans and fungal extracellular polysaccharides in house dust of (pre-)school children in three European countries, Environ. Int., 33, 9-16.
18. Heinrich, J., Gehring, U., Douwes, J., Koch, A., Fahlbusch, B., Bischof, W. and Wichmann, H.E. (2001) Pets and vermin are associated with high endotoxin levels in house dust, Clin. Exp. Allergy, 31, 1839-1845.
19. Heinrich, J., Bolte, G., Hölscher, B., Douwes, J., Lehmann, I., Fahlbusch, B., Bischof, W., Weiss, M., Borte, M. and Wichmann, H.E. (2002) Allergens and endotoxin on mothers' mattresses and total immunoglobulin E in cord blood of neonates, Eur. Respir. J., 20, 617-623.
20. Lappalainen, M.H.J., Huttunen, K., Roponen, M., Remes, S., Hirvonen, M.-R. and Pekkanen, J. (2010) Exposure to dogs is associated with a decreased tumour necrosis factor-α-producing capacity in early life, Clin. Exp. Allergy, 40, 1498-1506.
21. Schram, D., Doekes, G., Boeve, M., Douwes, J., Riedler, J., Ublagger, E., von Mutius, E., Budde, J., Pershagen, G., Nyberg, F., Alm, J., Braun-Fahrländer, C., Waser, M. and Brunekreef, B. (2005) Bacterial and fungal components in house dust of farm children. Rudolf Steiner school children and reference children-the PARSIFAL Study, Allergy, 60, 611-618.
22. Sordillo, J.E., Alwis, U.K., Hoffman, E., Gold, D.R. and Milton, D.K. (2011) Home characteristics as predictors of bacterial and fungal microbial biomarkers in house dust, Environ. Health Perspect., 119, 189-195.
23. Spaan, S., Smit, L.A., Eduard, W., Larsson, L., Arts, H.J., Wouters, I.M. and Heederik, D.J. (2008) Endotoxin exposure in sewage treatment workers: investigation of exposure variability and comparison of analytical techniques, Ann. Agric. Environ. Med., 15, 1050-1059.
24. Strachan, D.P. (1989) Hay fever, hygiene, and household size, BMJ (Clin Res Ed.), 299, 1259-1260.
25. Thorne, P.S., Cohn, R.D., Mav, D., Arbes, S.J. and Zeldin, D.C. (2009) Predictors of endotoxin levels in U.S. housing, Environ. Health Perspect., 117, 763-771.
26. Tischer, C., Gehring, U., Chen, C.-M., Kerkhof, M., Koppelman, G., Sausenthaler, S., Herbarth, O., Schaaf, B., Lehmann, I., Krämer, U., Berdel, D., von Berg, A., Bauer, C.P., Koletzko, S., Wichmann, H.-E., Brunekreef, B. and Heinrich, J. (2011) Respiratory health in children, and indoor exposure to (1, 3)-β-D-glucan. EPS mould components and endotoxin, Eur. Respir. J., 37, 1050-1059.
27. Torrent, M., Sunyer, J., Garcia, R., Harris, J., Iturriaga, M.V., Puig, C., Vall, O., Anto, J.M., Newman Taylor, A.J. and Cullinan, P. (2007) Early-life allergen exposure and atopy, asthma, and wheeze up to 6 years of age, Am. J. Respir. Crit. Care Med., 176, 446-453.
28. Waser, M., Schierl, R., von Mutius, E., Maisch, S., Carr, D., Riedler, J., Eder, W., Schreuer, M., Nowak, D. and Braun-Fahrländer, C. (2004) Determinants of endotoxin levels in living environments of farmers' children and their peers from rural areas, Clin. Exp. Allergy, 34, 389-397.