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Volumn 75, Issue 3, 2015, Pages 584-593

PDGFRα and β play critical roles in mediating Foxq1-driven breast cancer stemness and chemoresistance

Author keywords

[No Author keywords available]

Indexed keywords

FOXQ1 PROTEIN; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; TUMOR MARKER; TUMOR PROTEIN; TWIST1 PROTEIN; UNCLASSIFIED DRUG; ZEB2 PROTEIN; ANTINEOPLASTIC AGENT; FORKHEAD TRANSCRIPTION FACTOR; FOXQ1 PROTEIN, HUMAN; FOXQ1 PROTEIN, MOUSE; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR TWIST; TWIST1 PROTEIN, HUMAN;

EID: 84961288303     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-3029     Document Type: Article
Times cited : (67)

References (49)
  • 2
    • 75649151387 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cancer development and its clinical significance
    • Iwatsuki M, Mimori K, Yokobori T, Ishi H, Beppu T, Nakamori S, et al. Epithelial-mesenchymal transition in cancer development and its clinical significance. Cancer Sci 2010;101:293-9.
    • (2010) Cancer Sci , vol.101 , pp. 293-299
    • Iwatsuki, M.1    Mimori, K.2    Yokobori, T.3    Ishi, H.4    Beppu, T.5    Nakamori, S.6
  • 3
    • 34247572006 scopus 로고    scopus 로고
    • Src, chemoresistance and epithelial to mesenchymal transition: Are they related?
    • Shah AN, Gallick GE. Src, chemoresistance and epithelial to mesenchymal transition: are they related? Anticancer Drugs 2007;18:371-5.
    • (2007) Anticancer Drugs , vol.18 , pp. 371-375
    • Shah, A.N.1    Gallick, G.E.2
  • 4
    • 84869045299 scopus 로고    scopus 로고
    • Elf5 inhibits the epithelial-mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2
    • Chakrabarti R, Hwang J, Andres Blanco M, Wei Y, Lukacisin M, Romano RA, et al. Elf5 inhibits the epithelial-mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2. Nat Cell Biol 2012;14:1212-22.
    • (2012) Nat Cell Biol , vol.14 , pp. 1212-1222
    • Chakrabarti, R.1    Hwang, J.2    Andres Blanco, M.3    Wei, Y.4    Lukacisin, M.5    Romano, R.A.6
  • 5
    • 84860397754 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition markers expressed in circulating tumour cells of early and metastatic breast cancer patients
    • Kallergi G, Papadaki MA, Politaki E, Mavroudis D, Georgoulias V, Agelaki S. Epithelial to mesenchymal transition markers expressed in circulating tumour cells of early and metastatic breast cancer patients. Breast Cancer Res 2011;13:R59.
    • (2011) Breast Cancer Res , vol.13 , pp. R59
    • Kallergi, G.1    Papadaki, M.A.2    Politaki, E.3    Mavroudis, D.4    Georgoulias, V.5    Agelaki, S.6
  • 6
    • 84867985560 scopus 로고    scopus 로고
    • The rejuvenated scenario of epithelial-mesenchymal transition (EMT) and cancer metastasis
    • Meng F, Wu G. The rejuvenated scenario of epithelial-mesenchymal transition (EMT) and cancer metastasis. Cancer Metastasis Rev 2012;31:455-67.
    • (2012) Cancer Metastasis Rev , vol.31 , pp. 455-467
    • Meng, F.1    Wu, G.2
  • 7
    • 77954860342 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cancer: Parallels between normal development and tumor progression
    • Micalizzi DS, Farabaugh SM, Ford HL. Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression. J Mammary Gland Biol Neoplasia 2010;15:117-34.
    • (2010) J Mammary Gland Biol Neoplasia , vol.15 , pp. 117-134
    • Micalizzi, D.S.1    Farabaugh, S.M.2    Ford, H.L.3
  • 8
    • 84887559834 scopus 로고    scopus 로고
    • Sox4, EMT programs, and the metastatic progression of breast cancers: Mastering the masters of EMT
    • Parvani JG, Schiemann WP. Sox4, EMT programs, and the metastatic progression of breast cancers: mastering the masters of EMT. Breast Cancer Res 2013;15:R72.
    • (2013) Breast Cancer Res , vol.15 , pp. R72
    • Parvani, J.G.1    Schiemann, W.P.2
  • 9
    • 70449697859 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitionwith expression of SNAI1-induced chemoresistance in colorectal cancer
    • Hoshino H, Miyoshi N, Nagai K, Tomimaru Y, Nagano H, Sekimoto M, et al. Epithelial-mesenchymal transitionwith expression of SNAI1-induced chemoresistance in colorectal cancer. Biochem Biophys Res Commun 2009;390:1061-5.
    • (2009) Biochem Biophys Res Commun , vol.390 , pp. 1061-1065
    • Hoshino, H.1    Miyoshi, N.2    Nagai, K.3    Tomimaru, Y.4    Nagano, H.5    Sekimoto, M.6
  • 10
    • 70349859809 scopus 로고    scopus 로고
    • Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells
    • Kurrey NK, Jalgaonkar SP, Joglekar AV, Ghanate AD, Chaskar PD, Doiphode RY, et al. Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells. Stem Cells 2009;27:2059-68.
    • (2009) Stem Cells , vol.27 , pp. 2059-2068
    • Kurrey, N.K.1    Jalgaonkar, S.P.2    Joglekar, A.V.3    Ghanate, A.D.4    Chaskar, P.D.5    Doiphode, R.Y.6
  • 11
    • 34347358621 scopus 로고    scopus 로고
    • Upregulation of Twist-1 by NF-kappaB blocks cytotoxicity induced by chemotherapeutic drugs
    • Pham CG, Bubici C, Zazzeroni F, Knabb JR, Papa S, Kuntzen C, et al. Upregulation of Twist-1 by NF-kappaB blocks cytotoxicity induced by chemotherapeutic drugs. Mol Cell Biol 2007;27:3920-35.
    • (2007) Mol Cell Biol , vol.27 , pp. 3920-3935
    • Pham, C.G.1    Bubici, C.2    Zazzeroni, F.3    Knabb, J.R.4    Papa, S.5    Kuntzen, C.6
  • 12
    • 84875473628 scopus 로고    scopus 로고
    • FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer
    • Hollier BG, Tinnirello AA, Werden SJ, Evans KW, Taube JH, Sarkar TR, et al. FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer. Cancer Res 2013;73:1981-92.
    • (2013) Cancer Res , vol.73 , pp. 1981-1992
    • Hollier, B.G.1    Tinnirello, A.A.2    Werden, S.J.3    Evans, K.W.4    Taube, J.H.5    Sarkar, T.R.6
  • 13
    • 44649163918 scopus 로고    scopus 로고
    • A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
    • Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna S, et al. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 2008;9:582-9.
    • (2008) EMBO Rep , vol.9 , pp. 582-589
    • Burk, U.1    Schubert, J.2    Wellner, U.3    Schmalhofer, O.4    Vincan, E.5    Spaderna, S.6
  • 14
    • 84895924719 scopus 로고    scopus 로고
    • Loss of the polycomb protein Mel-18 enhances the epithelial-mesenchymal transition by ZEB1 and ZEB2 expression through the downregulation of miR-205 in breast cancer
    • Lee JY, Park MK, Park JH, Lee HJ, Shin DH, Kang Y, et al. Loss of the polycomb protein Mel-18 enhances the epithelial-mesenchymal transition by ZEB1 and ZEB2 expression through the downregulation of miR-205 in breast cancer. Oncogene 2014;33:1325-35.
    • (2014) Oncogene , vol.33 , pp. 1325-1335
    • Lee, J.Y.1    Park, M.K.2    Park, J.H.3    Lee, H.J.4    Shin, D.H.5    Kang, Y.6
  • 15
    • 0036387193 scopus 로고    scopus 로고
    • Forkhead transcription factors: Key players in development and metabolism
    • Carlsson P, Mahlapuu M. Forkhead transcription factors: key players in development and metabolism. Dev Biol 2002;250:1-23.
    • (2002) Dev Biol , vol.250 , pp. 1-23
    • Carlsson, P.1    Mahlapuu, M.2
  • 16
    • 15044366139 scopus 로고    scopus 로고
    • Forkhead transcription factors in immunology
    • Jonsson H, Peng SL. Forkhead transcription factors in immunology. Cell Mol Life Sci 2005;62:397-409.
    • (2005) Cell Mol Life Sci , vol.62 , pp. 397-409
    • Jonsson, H.1    Peng, S.L.2
  • 17
    • 16644382513 scopus 로고    scopus 로고
    • Human FOX gene family (Review)
    • Katoh M, Katoh M. Human FOX gene family (Review). Int J Oncol 2004;25:1495-500.
    • (2004) Int J Oncol , vol.25 , pp. 1495-1500
    • Katoh, M.1    Katoh, M.2
  • 18
    • 0034613386 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor-3 homologue 1 (HFH-1) represses transcription of smooth muscle-specific genes
    • Hoggatt AM, Kriegel AM, Smith AF, Herring BP. Hepatocyte nuclear factor-3 homologue 1 (HFH-1) represses transcription of smooth muscle-specific genes. J Biol Chem 2000;275:31162-70.
    • (2000) J Biol Chem , vol.275 , pp. 31162-31170
    • Hoggatt, A.M.1    Kriegel, A.M.2    Smith, A.F.3    Herring, B.P.4
  • 19
    • 18144403832 scopus 로고    scopus 로고
    • Differences in gene expression between wild type and Hoxa1 knockout embryonic stem cells after retinoic acid treatment or leukemia inhibitory factor (LIF) removal
    • Martinez-Ceballos E, Chambon P, Gudas LJ. Differences in gene expression between wild type and Hoxa1 knockout embryonic stem cells after retinoic acid treatment or leukemia inhibitory factor (LIF) removal. J Biol Chem 2005;280:16484-98.
    • (2005) J Biol Chem , vol.280 , pp. 16484-16498
    • Martinez-Ceballos, E.1    Chambon, P.2    Gudas, L.J.3
  • 20
    • 33749417322 scopus 로고    scopus 로고
    • Evidence that the satin hair mutant gene Foxq1 is among multiple and functionally diverse regulatory targets for Hoxc13 during hair follicle differentiation
    • Potter CS, Peterson RL, Barth JL, Pruett ND, Jacobs DF, Kern MJ, et al. Evidence that the satin hair mutant gene Foxq1 is among multiple and functionally diverse regulatory targets for Hoxc13 during hair follicle differentiation. J Biol Chem 2006;281:29245-55.
    • (2006) J Biol Chem , vol.281 , pp. 29245-29255
    • Potter, C.S.1    Peterson, R.L.2    Barth, J.L.3    Pruett, N.D.4    Jacobs, D.F.5    Kern, M.J.6
  • 22
    • 22144450017 scopus 로고    scopus 로고
    • Identification of novel highly expressed genes in pancreatic ductal adenocarcinomas through a bioinformatics analysis of expressed sequence tags
    • Cao D, Hustinx SR, Sui G, Bala P, Sato N, Martin S, et al. Identification of novel highly expressed genes in pancreatic ductal adenocarcinomas through a bioinformatics analysis of expressed sequence tags. Cancer Biol Ther 2004;3:1081-9.
    • (2004) Cancer Biol Ther , vol.3 , pp. 1081-1089
    • Cao, D.1    Hustinx, S.R.2    Sui, G.3    Bala, P.4    Sato, N.5    Martin, S.6
  • 23
    • 77950219816 scopus 로고    scopus 로고
    • FOXQ1 is overexpressed in colorectal cancer and enhances tumorigenicity and tumor growth
    • Kaneda H, Arao T, Tanaka K, Tamura D, Aomatsu K, Kudo K, et al. FOXQ1 is overexpressed in colorectal cancer and enhances tumorigenicity and tumor growth. Cancer Res 2010;70:2053-63.
    • (2010) Cancer Res , vol.70 , pp. 2053-2063
    • Kaneda, H.1    Arao, T.2    Tanaka, K.3    Tamura, D.4    Aomatsu, K.5    Kudo, K.6
  • 24
    • 67651005826 scopus 로고    scopus 로고
    • Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancer
    • Bierie B, Chung CH, Parker JS, Stover DG, Cheng N, Chytil A, et al. Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancer. J Clin Invest 2009;119:1571-82.
    • (2009) J Clin Invest , vol.119 , pp. 1571-1582
    • Bierie, B.1    Chung, C.H.2    Parker, J.S.3    Stover, D.G.4    Cheng, N.5    Chytil, A.6
  • 26
    • 79951849322 scopus 로고    scopus 로고
    • Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis
    • Zhang H, Meng F, Liu G, Zhang B, Zhu J, Wu F, et al. Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis. Cancer Res 2011;71:1292-301.
    • (2011) Cancer Res , vol.71 , pp. 1292-1301
    • Zhang, H.1    Meng, F.2    Liu, G.3    Zhang, B.4    Zhu, J.5    Wu, F.6
  • 27
    • 79954577486 scopus 로고    scopus 로고
    • FOXQ1 regulates epithelial-mesenchymal transition in human cancers
    • Qiao Y, Jiang X, Lee ST, Karuturi RK, Hooi SC, Yu Q. FOXQ1 regulates epithelial-mesenchymal transition in human cancers. Cancer Res 2011;71:3076-86.
    • (2011) Cancer Res , vol.71 , pp. 3076-3086
    • Qiao, Y.1    Jiang, X.2    Lee, S.T.3    Karuturi, R.K.4    Hooi, S.C.5    Yu, Q.6
  • 28
    • 51449085561 scopus 로고    scopus 로고
    • Generation of breast cancer stem cells through epithelial-mesenchymal transition
    • Morel AP, Lievre M, Thomas C, Hinkal G, Ansieau S, Puisieux A. Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLoS ONE 2008;3:e2888.
    • (2008) PLoS ONE , vol.3 , pp. e2888
    • Morel, A.P.1    Lievre, M.2    Thomas, C.3    Hinkal, G.4    Ansieau, S.5    Puisieux, A.6
  • 29
    • 77952829803 scopus 로고    scopus 로고
    • Disulfiram treatment facilitates phosphoinositide 3-kinase inhibition in human breast cancer cells in vitro and in vivo
    • Zhang H, Chen D, Ringler J, Chen W, Cui QC, Ethier SP, et al. Disulfiram treatment facilitates phosphoinositide 3-kinase inhibition in human breast cancer cells in vitro and in vivo. Cancer Res 2010;70:3996-4004.
    • (2010) Cancer Res , vol.70 , pp. 3996-4004
    • Zhang, H.1    Chen, D.2    Ringler, J.3    Chen, W.4    Cui, Q.C.5    Ethier, S.P.6
  • 30
    • 53949099847 scopus 로고    scopus 로고
    • Comprehensive analysis of oncogenic effects of PIK3CA mutations in human mammary epithelial cells
    • Zhang H, Liu G, Dziubinski M, Yang Z, Ethier SP, Wu G. Comprehensive analysis of oncogenic effects of PIK3CA mutations in human mammary epithelial cells. Breast Cancer Res Treat 2008;112:217-27.
    • (2008) Breast Cancer Res Treat , vol.112 , pp. 217-227
    • Zhang, H.1    Liu, G.2    Dziubinski, M.3    Yang, Z.4    Ethier, S.P.5    Wu, G.6
  • 31
    • 79960415851 scopus 로고    scopus 로고
    • Engagement of I-branching {beta}-1, 6-N-acetylglucosaminyltransferase 2 in breast cancer metastasis and TGF-{beta} signaling
    • Zhang H, Meng F, Wu S, Kreike B, Sethi S, Chen W, et al. Engagement of I-branching {beta}-1, 6-N-acetylglucosaminyltransferase 2 in breast cancer metastasis and TGF-{beta} signaling. Cancer Res 2011;71:4846-56.
    • (2011) Cancer Res , vol.71 , pp. 4846-4856
    • Zhang, H.1    Meng, F.2    Wu, S.3    Kreike, B.4    Sethi, S.5    Chen, W.6
  • 32
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008;133:704-15.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.J.3    Eaton, E.N.4    Ayyanan, A.5    Zhou, A.Y.6
  • 34
    • 33750470097 scopus 로고    scopus 로고
    • CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells
    • Sleeman KE, Kendrick H, Ashworth A, Isacke CM, Smalley MJ. CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells. Breast Cancer Res 2006;8:R7.
    • (2006) Breast Cancer Res , vol.8 , pp. R7
    • Sleeman, K.E.1    Kendrick, H.2    Ashworth, A.3    Isacke, C.M.4    Smalley, M.J.5
  • 35
    • 12144261476 scopus 로고    scopus 로고
    • Oncogenic derivatives of platelet-derived growth factor receptors
    • Jones AV, Cross NC. Oncogenic derivatives of platelet-derived growth factor receptors. Cell Mol Life Sci 2004;61:2912-23.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 2912-2923
    • Jones, A.V.1    Cross, N.C.2
  • 36
    • 84861789402 scopus 로고    scopus 로고
    • Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity
    • Kim Y, Kim E, Wu Q, Guryanova O, Hitomi M, Lathia JD, et al. Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity. Genes Dev 2012;26:1247-62.
    • (2012) Genes Dev , vol.26 , pp. 1247-1262
    • Kim, Y.1    Kim, E.2    Wu, Q.3    Guryanova, O.4    Hitomi, M.5    Lathia, J.D.6
  • 37
    • 84869221316 scopus 로고    scopus 로고
    • PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas
    • Laimer D, Dolznig H, Kollmann K, Vesely PW, Schlederer M, Merkel O, et al. PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas. Nat Med 2012;18:1699-704.
    • (2012) Nat Med , vol.18 , pp. 1699-1704
    • Laimer, D.1    Dolznig, H.2    Kollmann, K.3    Vesely, P.W.4    Schlederer, M.5    Merkel, O.6
  • 38
    • 34047127376 scopus 로고    scopus 로고
    • PDGF receptors as targets in tumor treatment
    • Ostman A, Heldin CH. PDGF receptors as targets in tumor treatment. Adv Cancer Res 2007;97:247-74.
    • (2007) Adv Cancer Res , vol.97 , pp. 247-274
    • Ostman, A.1    Heldin, C.H.2
  • 39
    • 4644276702 scopus 로고    scopus 로고
    • Imatinib targets other than bcr/abl and their clinical relevance in myeloid disorders
    • Pardanani A, Tefferi A. Imatinib targets other than bcr/abl and their clinical relevance in myeloid disorders. Blood 2004;104:1931-9.
    • (2004) Blood , vol.104 , pp. 1931-1939
    • Pardanani, A.1    Tefferi, A.2
  • 40
    • 46849094734 scopus 로고    scopus 로고
    • Molecular mechanisms of action of imatinib mesylate in human ovarian cancer: A proteomic analysis
    • Patel BB, He YA, Li XM, Frolov A, Vanderveer L, Slater C, et al. Molecular mechanisms of action of imatinib mesylate in human ovarian cancer: a proteomic analysis. Cancer Genomics Proteomics 2008;5:137-49.
    • (2008) Cancer Genomics Proteomics , vol.5 , pp. 137-149
    • Patel, B.B.1    He, Y.A.2    Li, X.M.3    Frolov, A.4    Vanderveer, L.5    Slater, C.6
  • 43
    • 0027980975 scopus 로고
    • Inhibition of glioma cell growth by a truncated platelet-derived growth factor-beta receptor
    • Strawn LM, Mann E, Elliger SS, Chu LM, Germain LL, Niederfellner G, et al. Inhibition of glioma cell growth by a truncated platelet-derived growth factor-beta receptor. J Biol Chem 1994;269:21215-22.
    • (1994) J Biol Chem , vol.269 , pp. 21215-21222
    • Strawn, L.M.1    Mann, E.2    Elliger, S.S.3    Chu, L.M.4    Germain, L.L.5    Niederfellner, G.6
  • 44
    • 10744227995 scopus 로고    scopus 로고
    • Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases
    • Uehara H, Kim SJ, Karashima T, Shepherd DL, Fan D, Tsan R, et al. Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases. J Natl Cancer Inst 2003;95:458-70.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 458-470
    • Uehara, H.1    Kim, S.J.2    Karashima, T.3    Shepherd, D.L.4    Fan, D.5    Tsan, R.6
  • 45
    • 0026597964 scopus 로고
    • Platelet-derived growth factor: Isoform-specific signalling via heterodimeric or homodimeric receptor complexes
    • Heldin CH, Ostman A, Eriksson A, Siegbahn A, Claesson-Welsh L, Westermark B. Platelet-derived growth factor: isoform-specific signalling via heterodimeric or homodimeric receptor complexes. Kidney Int 1992;41:571-4.
    • (1992) Kidney Int , vol.41 , pp. 571-574
    • Heldin, C.H.1    Ostman, A.2    Eriksson, A.3    Siegbahn, A.4    Claesson-Welsh, L.5    Westermark, B.6
  • 46
    • 0026583942 scopus 로고
    • PDGF alpha- and beta-receptors activate unique and common signal transduction pathways
    • Eriksson A, Siegbahn A, Westermark B, Heldin CH, Claesson-Welsh L. PDGF alpha- and beta-receptors activate unique and common signal transduction pathways. EMBO J 1992;11:543-50.
    • (1992) EMBO J , vol.11 , pp. 543-550
    • Eriksson, A.1    Siegbahn, A.2    Westermark, B.3    Heldin, C.H.4    Claesson-Welsh, L.5
  • 48
    • 0035106689 scopus 로고    scopus 로고
    • The two PDGF receptors maintain conserved signaling in vivo despite divergent embryological functions
    • Klinghoffer RA, Mueting-Nelsen PF, Faerman A, Shani M, Soriano P. The two PDGF receptors maintain conserved signaling in vivo despite divergent embryological functions. Mol Cell 2001;7:343-54.
    • (2001) Mol Cell , vol.7 , pp. 343-354
    • Klinghoffer, R.A.1    Mueting-Nelsen, P.F.2    Faerman, A.3    Shani, M.4    Soriano, P.5


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