The evolving landscape of imprinted genes in humans and mice: Conflict among alleles, genes, tissues, and kin

BioEssays

Volumn 38, Issue 5, 2016, Pages 482-489

  Wilkins, Jon F ^a   Úbeda, Francisco ^b   Van Cleve, Jeremy ^c  

^a RONIN INSTITUTE   (United States)

^b UNIVERSITY OF LONDON   (United Kingdom)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Genome wide map; Genomic imprinting; Grb10; Igf2; Intragenomic conflict; Kinship theory; RNA seq

Indexed keywords

GROWTH FACTOR RECEPTOR BOUND PROTEIN 10; SOMATOMEDIN; GRB10 PROTEIN, HUMAN; IGF2 PROTEIN, HUMAN; SOMATOMEDIN B;

ADULT; ALLELISM; ARTICLE; CONSANGUINITY; EMBRYO; GENE EXPRESSION; GENE LOCUS; GENETIC ASSOCIATION; GENOME IMPRINTING; HUMAN; MOUSE; NONHUMAN; ALLELE; ANIMAL; ANTIBODY SPECIFICITY; BIOLOGICAL MODEL; EVOLUTION; FEMALE; GENETICS; GENOME; GENOME-WIDE ASSOCIATION STUDY; MALE; SPECIES DIFFERENCE;

ALLELES; ANIMALS; BIOLOGICAL EVOLUTION; FEMALE; GENETIC LOCI; GENOME; GENOME-WIDE ASSOCIATION STUDY; GENOMIC IMPRINTING; GRB10 ADAPTOR PROTEIN; HUMANS; INSULIN-LIKE GROWTH FACTOR II; MALE; MICE; MODELS, GENETIC; ORGAN SPECIFICITY; SPECIES SPECIFICITY;

EID: 84961267002     PISSN: 02659247     EISSN: 15211878     Source Type: Journal    
DOI: 10.1002/bies.201500198     Document Type: Article

References (53)

1. Bartolomei MS, Tilghman SM. 1997. Genomic imprinting in mammals. Annu Rev Genet 31: 493-525.
2. Barlow DP, Bartolomei MS. 2014. Genomic imprinting in mammals. Cold Spring Harb Perspect Biol 6: a018382.
3. Babak T, DeVeale B, Tsang EK, Zhou Y, et al. 2015. Genetic conflict reflected in tissue-specific maps of genomic imprinting in human and mouse. Nat Genet 47: 544-9.
4. Baran Y, Subramaniam M, Biton A, Tukiainen T, et al. 2015. The landscape of genomic imprinting across diverse adult human tissues. Genome Res 25: 927-36.
5. Crowley JJ, Zhabotynsky V, Sun W, Huang S, et al. 2015. Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance. Nat Genet 47: 353-60.
6. Patten MM, Ross L, Curley JP, Queller DC, et al. 2014. The evolution of genomic imprinting: theories, predictions, and empirical tests. Heredity 113: 119-28.
7. Babak T, Deveale B, Armour C, Raymond C, et al. 2008. Global survey of genomic imprinting by transcriptome sequencing. Curr Biol 18: 1735-41.
8. Wang X, Sun Q, McGrath SD, Mardis ER, et al. 2008. Transcriptome-wide identification of novel imprinted genes in neonatal mouse brain. PLoS ONE 3: e3839.
9. Morison IM, Ramsay JP, Spencer HG. 2005. A census of mammalian imprinting. Trends Genet 21: 457-65.
10. Gregg C, Zhang J, Weissbourd B, Luo S, et al. 2010. High-resolution analysis of parent-of-origin allelic expression in the mouse brain. Science 329: 643-8.
11. DeVeale B, van der Kooy D, Babak T. 2012. Critical evaluation of imprinted gene expression by RNA-Seq: a new perspective. PLoS Genet 8: e1002600.
12. Lonsdale J, Thomas J, Salvatore M, Phillips R, et al. 2013. The genotype-tissue expression (GTEx) project. Nat Genet 45: 580-5.
13. Kelsey G, Feil R. 2013. New insights into establishment and maintenance of DNA methylation imprints in mammals. Philos Trans R Soc B 368:20110336.
14. Spencer HG, Clark AG. 2014. Non-conflict theories for the evolution of genomic imprinting. Heredity 113: 112-8.
15. Van Cleve J, Feldman MW. 2007. Sex-specific viability, sex linkage, and dominance in genomic imprinting. Genetics 176: 1101-18.
16. Haig D. 2000. The kinship theory of genomic imprinting. Annu Rev Ecol Syst 31: 9-32.
17. Wilkins JF, Haig D. 2003. What good is genomic imprinting: the function of parent-specific gene expression. Nat Rev Genet 4: 359-68.
18. Úbeda F, Gardner A. 2010. A model for genomic imprinting in the social brain: juveniles. Evolution 64: 2587-600.
19. Van Cleve J, Feldman MW, Lehmann L. 2010. How demography, life history, and kinship shape the evolution of genomic imprinting. Am Nat 176: 440-55.
20. Úbeda F, Gardner A. 2011. A model for genomic imprinting in the social brain: adults. Evolution 65: 462-75.
21. Úbeda F, Gardner A. 2012. A model for genomic imprinting in the social brain: elders. Evolution 66: 1567-81.
22. Haig D. 1992. Genomic imprinting and the theory of parent-offspring conflict. Semin Dev Biol 3: 153-60.
23. Haig D. 1997. Parental antagonism, relatedness asymmetries, and genomic imprinting. Proc R Soc B 264: 1657-62.
24. Brandvain Y, Van Cleve J, Úbeda F, Wilkins JF. 2011. Demography, kinship, and the evolving theory of genomic imprinting. Trends Genet 27: 251-7.
25. Úbeda F, Gardner A. 2015. Mother and offspring in conflict: why not? PLoS Biol 13: e1002084.
26. Sibley CP, Coan PM, Ferguson-Smith AC, Dean W, et al. 2004. Placental-specific insulin-like growth factor 2 (Igf2) regulates the diffusional exchange characteristics of the mouse placenta. Proc Natl Acad Sci USA 101: 8204-8.
27. Reik W, Walter J. 2001. Genomic imprinting: parental influence on the genome. Nat Rev Genet 2: 21-32.
28. Wilkins JF, Haig D. 2001. Genomic imprinting of two antagonistic loci. Proc R Soc B 268: 1861-7.
29. Wilkins JF. 2010. Antagonistic coevolution of two imprinted loci with pleiotropic effects. Evolution 64: 142-51.
30. Wilkins JF. 2011. Genomic imprinting and conflict-induced decanalization. Evolution 65: 537-53.
31. Madon-Simon M, Cowley M, Garfield AS, Moorwood K, et al. 2014. Antagonistic roles in fetal development and adult physiology for the oppositely imprinted Grb10 and Dlk1 genes. BMC Biol 12: 771.
32. Keverne EB, Martel FL, Nevison CM. 1996. Primate brain evolution: genetic and functional considerations. Proc R Soc B 263: 689-96.
33. Úbeda F. 2008. Evolution of genomic imprinting with biparental care: implications for Prader-Willi and Angelman syndromes. PLoS Biol 6: e208.
34. DeChiara TM, Robertson EJ, Efstratiadis A. 1991. Parental imprinting of the mouse insulin-like growth factor II gene. Cell 64: 849-59.
35. Ferguson-Smith AC, Cattanach BM, Barton SC, Beechey CV, et al. 1991. Embryological and molecular investigations of parental imprinting on mouse chromosome 7. Nature 351: 667-70.
36. Constância M, Hemberger M, Hughes J, Dean W, et al. 2002. Placental-specific IGF-II is a major modulator of placental and fetal growth. Nature 417: 945-8.
37. Ye X, Kohtz A, Pollonini G, Riccio A, et al. 2015. Insulin like growth factor 2 expression in the rat brain both in basal condition and following learning predominantly derives from the maternal allele. PLoS ONE 10: e0141078.
38. Bracko O, Singer T, Aigner S, Knobloch M, et al. 2012. Gene expression profiling of neural stem cells and their neuronal progeny reveals IGF2 as a regulator of adult hippocampal neurogenesis. J Neurosci 32: 3376-87.
39. Ferrón SR, Radford EJ, Domingo-Muelas A, Kleine I, et al. 2015. Differential genomic imprinting regulates paracrine and autocrine roles of IGF2 in mouse adult neurogenesis. Nat Commun 6: 8265.
40. Charalambous M, Smith FM, Bennett WR, Crew TE, et al. 2003. Disruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanism. Proc Natl Acad Sci USA 100: 8292-7.
41. Charalambous M, Cowley M, Geoghegan F, Smith FM, et al. 2010. Maternally-inherited Grb10 reduces placental size and efficiency. Dev Biol 337: 1-8.
42. Garfield AS, Cowley M, Smith FM, Moorwood K, et al. 2011. Distinct physiological and behavioural functions for parental alleles of imprinted Grb10. Nature 469: 534-8.
43. Arnaud P, Monk D, Hitchins M, Gordon E, et al. 2003. Conserved methylation imprints in the human and mouse GRB10 genes with divergent allelic expression suggests differential reading of the same mark. Hum Mol Genet 12: 1005-19.
44. Monk D, Arnaud P, Frost J, Hills FA, et al. 2009. Reciprocal imprinting of human GRB10 in placental trophoblast and brain: evolutionary conservation of reversed allelic expression. Hum Mol Genet 18: 3066-74.
45. Úbeda F, Haig D. 2003. Dividing the child. Genetica 117: 103-10.
46. Burt A, Trivers R. 1998. Genetic conflicts in genomic imprinting. Proc R Soc B 265: 2393-7.
47. Wilkins JF. 2005. Genomic imprinting and methylation: epigenetic canalization and conflict. Trends Genet 21: 356-65.
48. Wilkins JF, Haig D. 2002. Parental modifiers, antisense transcripts and loss of imprinting. Proc R Soc B 269: 1841-6.
49. Arnaud P. 2010. Genomic imprinting in germ cells: imprints are under control. Reproduction 140: 411-23.
50. Court F, Tayama C, Romanelli V, Martin-Trujillo A, et al. 2014. Genome-wide parent-of-origin DNA methylation analysis reveals the intricacies of human imprinting and suggests a germline methylation-independent mechanism of establishment. Genome Res 24: 554-69.
51. Davies JR, Dent CL, McNamara GI, Isles AR. 2015. Behavioural effects of imprinted genes. Curr Opin Behav Sci 2: 28-33.
52. Wilkins JF. 2006. Tissue-specific reactivation of gene expression at an imprinted locus. J Theor Biol 240: 277-87.
53. Spencer HG, Williams MJ. 1997. The evolution of genomic imprinting: two modifier-locus models. Theor Popul Biol 51: 23-35.