Roles for NK cells and an NK cell-independent source of intestinal gamma interferon for innate immunity to Cryptosporidium parvum infection

Infection and Immunity

Volumn 77, Issue 11, 2009, Pages 5044-5049

  Barakat, Farah M ^a   McDonald, Vincent ^a   Di Santo, James P ^b   Korbel, Daniel S ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 15 RECEPTOR; MESSENGER RNA; RAG2 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CELL FUNCTION; CELL TYPE; CONTROLLED STUDY; CRYPTOSPORIDIOSIS; INNATE IMMUNITY; INTESTINE; MORBIDITY; MORTALITY; MOUSE; NATURAL KILLER CELL; NEWBORN; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE;

ANIMALS; CRYPTOSPORIDIOSIS; CRYPTOSPORIDIUM PARVUM; IMMUNITY, INNATE; INTERFERON-GAMMA; INTESTINES; KILLER CELLS, NATURAL; MICE; MICE, KNOCKOUT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 70350463563     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00377-09     Document Type: Article

References (30)

1. Aguirre, S. A., P. H. Mason, and L. E. Perryman. 1994. Susceptibility of major histocompatibility complex (MHC) class I- and MHC class II-deficient mice to Cryptosporidium parvum infection. Infect. Immun. 62:697-699.
2. Blanshard, C., A. M. Jackson, D. C. Shanson, N. Francis, and B. G. Gazzard. 1992. Cryptosporidiosis in HIV-seropositive patients. Q. J. Med. 85:813-823.
3. Chen, X. M., J. S. Keithly, C. V. Paya, and N. F. LaRusso. 2002. Cryptosporidiosis. N. Engl. J. Med. 346:1723-1731.
4. Dann, S. M., H. C. Wang, K. J. Gambarin, J. K. Actor, P. Robinson, D. E. Lewis, S. Caillat-Zucman, and A. C. White, Jr. 2005. Interleukin-15 activates human natural killer cells to clear the intestinal protozoan Cryptosporidium. J. Infect. Dis. 192:1294-1302.
5. Di Santo, J. P. 2006. Natural killer cell developmental pathways: a question of balance. Annu. Rev. Immunol. 24:257-286.
6. Gomez Morales, M. A., G. La Rosa, A. Ludovisi, A. M. Onori, and E. Pozio. 1999. Cytokine profile induced by Cryptosporidium antigen in peripheral blood mononuclear cells from immunocompetent and immunosuppressed persons with cryptosporidiosis. J. Infect. Dis. 179:967-973.
7. Hayward, A. R., K. Chmura, and M. Cosyns. 2000. Interferon-gamma is required for innate immunity to Cryptosporidium parvum in mice. J. Infect. Dis. 182:1001-1004.
8. Kirby, A. C., U. Yrlid, and M. J. Wick. 2002. The innate immune response differs in primary and secondary Salmonella infection. J. Immunol. 169:4450-4459.
9. Korbel, D. S., O. C. Finney, and E. M. Riley. 2004. Natural killer cells and innate immunity to protozoan pathogens. Int. J. Parasitol. 34:1517-1528.
10. Lacroix-Lamande, S., R. Mancassola, M. Naciri, and F. Laurent. 2002. Role of gamma interferon in chemokine expression in the ileum of mice and in a murine intestinal epithelial cell line after Cryptosporidium parvum infection. Infect. Immun. 70:2090-2099.
11. Lugo-Villarino, G., R. Maldonado-Lopez, R. Possemato, C. Peneranda, and L. H. Glimcher. 2003. T-bet is required for optimal production of IFN-γ and antigen-specific T cell activation by dendritic cells. Proc. Natl. Acad. Sci. USA 100:7749-7754.
12. McDonald, S. A., J. O'Grady, M. Bajaj-Elliott, C. A. Notley, J. Alexander, F. Brombacher, and V. McDonald. 2004. Protection against the early phase of Cryptosporidium parvum infection conferred by interleukin-4-induced expression of T helper 1 cytokines. J. Infect. Dis. 190:1019-1025.
13. McDonald, V., R. Deer, S. Uni, M. Iseki, and G. J. Bancroft. 1992. Immune responses to Cryptosporidium muris and Cryptosporidium parvum in adult immunocompetent or immunocompromised (nude and SCID) mice. Infect. Immun. 60:3325-3331.
14. McDonald, V., and G. J. Bancroft. 1994. Mechanisms of innate and acquired resistance to Cryptosporidium parvum infection in SCID mice. Parasite Immunol. 16:315-320.
15. McDonald, V., R. Smith, H. Robinson, and G. Bancroft. 2000. Host immune responses against Cryptosporidium. Contrib. Microbiol. 6:75-91.
16. McDonald, V., R. C. Pollok, W. Dhaliwal, S. Naik, M. J. Farthing, and M. Bajaj-Elliott. 2006. A potential role for interleukin-18 in inhibition of the development of Cryptosporidium parvum. Clin. Exp. Immunol. 145:555-562.
17. Mead, J. R., M. J. Arrowood, R. W. Sidwell, and M. C. Healey. 1991. Chronic Cryptosporidium parvum infections in congenitally immunodeficient SCID and nude mice. J. Infect. Dis. 163:1297-1304.
18. Mead, J. R., and X. You. 1998. Susceptibility differences to Cryptosporidium parvum infection in two strains of gamma interferon knockout mice. J. Parasitol. 84:1045-1048.
19. Pollok, R. C., M. J. Farthing, M. Bajaj-Elliott, I. R. Sanderson, and V. McDonald. 2001. Interferon gamma induces enterocyte resistance against infection by the intracellular pathogen Cryptosporidium parvum. Gastroenterology 120:99-107.
20. Robinson, P., P. C. Okhusen, C. L. Chappell, D. E. Lewis, I. Shahab, and A. C. White, Jr. 2001. Expression of IL-15 and IL-4 in IFN-γ-independent control of experimental human Cryptosporidium parvum infection. Cytokine 15:39-46.
21. Rothfuchs, A. G., M. R. Kreuger, H. Wigzell, and M. E. Rottenberg. 2004. Macrophages, CD4+ or CD8+ cells are each sufficient for protection against Chlamydia pneumoniae infection through their ability to secrete IFN-gamma. J. Immunol. 172:2407-2415.
22. Schindler, H., M. B. Lutz, M. Rollinghoff, and C. Bogdan. 2001. The production of IFN-gamma by IL-12/IL-18-activated macrophages requires STAT4 signaling and is inhibited by IL-4. J. Immunol. 166:3075-3082. (Pubitemid 33117303)
23. Schmidt, W., U. Wahnschaffe, M. Schafer, T. Zippel, M. Arvand, A. Meyerhans, E. O. Riecken, and R. Ullrich. 2001. Rapid increase of mucosal CD4 T cells followed by clearance of intestinal cryptosporidiosis in an AIDS patient receiving highly active antiretroviral therapy. Gastroenterology 120: 984-987. (Pubitemid 32193195)
24. Sherwood, D., K. W. Angus, D. R. Snodgrass, and S. Tzipori. 1982. Experimental cryptosporidiosis in laboratory mice. Infect. Immun. 38:471-475.
25. Takeuchi, D., V. C. Jones, M. Kobayashi, and F. Suzuki. 2008. Cooperative role of macrophages and neutrophils in host antiprotozoan resistance in mice acutely infected with Cryptosporidium parvum. Infect. Immun. 76:3657-3663.
26. Tessema, T. S., B. Schwamb, M. Lochner, I. Forster, V. Jakobi, and F. Petry. 2009. Dynamics of gut mucosal and systemic Th1/Th2 cytokine responses in interferon-gamma and interleukin-12p40 knockout mice during primary and challenge Cryptosporidium parvum infection. Immunobiology 214:454-466.
27. Ungar, B. L., T. C. Kao, J. A. Burris, and F. D. Finkelman. 1991. Cryptosporidium infection in an adult mouse model. Independent roles for IFNgamma and CD4+ T lymphocytes in protective immunity. J. Immunol. 147:1014-1022.
28. Urban, J. F., Jr., R. Fayer, S. J. Chen, W. C. Gause, M. K. Gately, and F. D. Finkelman. 1996. IL-12 protects immunocompetent and immunodeficient neonatal mice against infection with Cryptosporidium parvum. J. Immunol. 156:263-268.
29. Wald, O., I. D. Weiss, H. Wald, H. Shoham, Y. Bar-Shavit, K. Beider, E. Galun, L. Weiss, L. Flaishon, I. Shachar, A. Nagler, B. Lu, C. Gerard, J. L. Gao, E. Mishani, J. Farber, and A. Peled. 2006. IFN-gamma acts on T cells to induce NK cell mobilization and accumulation in target organs. J. Immunol. 176:4716-4729.
30. Yoshihara, K., T. Yajima, C. Kubo, and Y. Yoshikai. 2006. Role of interleukin 15 in colitis induced by dextran sulphate sodium in mice. Gut 55:334-341. (Pubitemid 43268270)