Demethyleneberberine attenuates non-alcoholic fatty liver disease with activation of AMPK and inhibition of oxidative stress

Biochemical and Biophysical Research Communications

Volumn 472, Issue 4, 2016, Pages 603-609

  Qiang, Xiaoyan ^a,b   Xu, Lulu ^a   Zhang, Miao ^a   Zhang, Pengcheng ^a   Wang, Yinhang ^a   Wang, Yongchen ^a   Zhao, Zheng ^a   Chen, Huan ^a   Liu, Xie ^c   Zhang, Yubin ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c JIANGSU PROVINCIAL CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

Author keywords

AMPK; Demethyeneberberine; Hepatosteatosis; Inflammation; Non alcoholic liver disease; Oxidative stress

Indexed keywords

ABC TRANSPORTER G5; BERBERINE DERIVATIVE; CHOLINE; DEMETHYLENEBERBERINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INTERLEUKIN 1BETA; LIVER PROTECTIVE AGENT; MALONALDEHYDE; MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE; MESSENGER RNA; METHIONINE; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; NATURAL PRODUCT; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIOXIDANT; BERBERINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG MEGADOSE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FATTY ACID OXIDATION; GENE EXPRESSION; GENE FUNCTION; HEPATITIS; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPID DIET; LIPID LIVER LEVEL; LIPID METABOLISM; LIPID PEROXIDATION; LIPID STORAGE; LIVER PROTECTION; LOW DRUG DOSE; MALE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; DRUG EFFECTS; INSTITUTE FOR CANCER RESEARCH MOUSE; LIVER; METABOLISM; NON-ALCOHOLIC FATTY LIVER DISEASE; PATHOLOGY;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTIOXIDANTS; BERBERINE; ENZYME ACTIVATION; HEP G2 CELLS; HUMANS; LIPID METABOLISM; LIVER; MALE; MICE, INBRED C57BL; MICE, INBRED ICR; NON-ALCOHOLIC FATTY LIVER DISEASE; OXIDATIVE STRESS;

EID: 84961186751     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2016.03.019     Document Type: Article

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