The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis

Phytomedicine

Volumn 21, Issue 11, 2014, Pages 1373-1381

  Wu, Hao ^a   He, Kai ^a   Wang, Yanzhi ^a   Xue, Dongfang ^a   Ning, Na ^a   Zou, Zongyao ^a   Ye, Xiaoli ^a   Li, Xuegang ^a   Wang, Dezhen ^a   Pang, Jie ^a  

^a SOUTHWEST UNIVERSITY   (China)

Author keywords

Antihypercholesterolemia; CYP7A1; Jatrorrhizine; LDLR; Rhizoma Coptidis

Indexed keywords

ANTILIPEMIC AGENT; APICAL SODIUM DEPENDENT BILE SALT TRANSPORTER; BERBERINE; BILE ACID; CHOLESTEROL 7ALPHA MONOOXYGENASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYPOCHOLESTEROLEMIC AGENT; JATRORRHIZINE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; PROTEIN; SIMVASTATIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; CHOLESTEROL; COPTIS RHIZOME EXTRACT; HERBACEOUS AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG ISOLATION; DRUG MECHANISM; DRUG SAFETY; DRUG SCREENING; ENZYME LINKED IMMUNOSORBENT ASSAY; FECES; FEMALE; GENE EXPRESSION; HEMATOLOGICAL PARAMETERS; HISTOLOGY; LD 50; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; RHIZOMA COPTIDIS; SYRIAN HAMSTER; URINALYSIS; WEIGHT GAIN; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; BLOOD; CHEMISTRY; MESOCRICETUS; METABOLISM; PLANT ROOT; RANUNCULACEAE; SPRAGUE DAWLEY RAT; TOXICITY TESTING;

CRICETINAE; MESOCRICETUS AURATUS; MUS; RATTUS;

ANIMALS; ANTICHOLESTEREMIC AGENTS; BERBERINE; BILE ACIDS AND SALTS; CHOLESTEROL; CHOLESTEROL 7-ALPHA-HYDROXYLASE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; FEMALE; MALE; MESOCRICETUS; MICE; PLANT ROOTS; RANUNCULACEAE; RATS, SPRAGUE-DAWLEY; RECEPTORS, LDL; TOXICITY TESTS; TRIGLYCERIDES;

EID: 84906937535     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2014.05.002     Document Type: Article

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