A novel splenic B1 regulatory cell subset suppresses allergic disease through phosphatidylinositol 3-kinase–Akt pathway activation

Journal of Allergy and Clinical Immunology

Volumn 138, Issue 4, 2016, Pages 1170-1182.e9

  Matsushita, Takashi ^a   Le Huu, Doanh ^a,b   Kobayashi, Tadahiro ^a   Hamaguchi, Yasuhito ^a   Hasegawa, Minoru ^c   Naka, Kazuhito ^d   Hirao, Atsushi ^d   Muramatsu, Masamichi ^a   Takehara, Kazuhiko ^a   Fujimoto, Manabu ^e  

^a KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

^b HANOI MEDICAL UNIVERSITY   (Viet Nam)

^c UNIVERSITY OF FUKUI   (Japan)

^d KANAZAWA UNIVERSITY   (Japan)

^e UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

autoimmunity; B cells; B1 B cell; IL 10; marginal zone B cell; phosphatase and tensin homolog; phosphatidylinositol 3 kinase; regulatory B cell; Rodent

Indexed keywords

B7 ANTIGEN; CD9 ANTIGEN; INTERLEUKIN 10; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; ENZYME INHIBITOR;

ALLERGIC DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CONTACT ALLERGY; CONTROLLED STUDY; ENZYME ACTIVATION; IN VITRO STUDY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; ANIMAL; CLASSIFICATION; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; HUMAN; HYPERSENSITIVITY; IMMUNOLOGY; LYMPHOCYTE SUBPOPULATION; METABOLISM; SPLEEN;

ANIMALS; B-LYMPHOCYTES; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; HYPERSENSITIVITY; INTERLEUKIN-10; LYMPHOCYTE SUBSETS; MICE; MICROARRAY ANALYSIS; PHOSPHATIDYLINOSITOL 3-KINASE; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SPLEEN;

EID: 84961174187     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2015.12.1319     Document Type: Article

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