메뉴 건너뛰기




Volumn 123, Issue 6, 2009, Pages

CD4+CD25+ regulatory T cells suppress contact hypersensitivity reactions through a CD39, adenosine-dependent mechanism

Author keywords

adenosine; Contact hypersensitivity; endothelial cells; regulatory T cells; skinfold chamber

Indexed keywords

ADENOSINE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE TRIPHOSPHATE; CD39 ANTIGEN; TUMOR NECROSIS FACTOR ALPHA; APYRASE; CD4 ANTIGEN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERLEUKIN 2 RECEPTOR ALPHA; LEUKOCYTE ANTIGEN; PADGEM PROTEIN;

EID: 67649197277     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2009.03.022     Document Type: Article
Times cited : (93)

References (44)
  • 2
    • 0033985780 scopus 로고    scopus 로고
    • Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific
    • Thornton A.M., and Shevach E.M. Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific. J Immunol 164 (2000) 183-190
    • (2000) J Immunol , vol.164 , pp. 183-190
    • Thornton, A.M.1    Shevach, E.M.2
  • 3
    • 1642577126 scopus 로고    scopus 로고
    • TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice
    • Nakamura K., Kitani A., Fuss I., et al. TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice. J Immunol 172 (2004) 834-842
    • (2004) J Immunol , vol.172 , pp. 834-842
    • Nakamura, K.1    Kitani, A.2    Fuss, I.3
  • 4
    • 0033523607 scopus 로고    scopus 로고
    • An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
    • Asseman C., Mauze S., Leach M.W., Coffman R.L., and Powrie F. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J Exp Med 190 (1999) 995-1004
    • (1999) J Exp Med , vol.190 , pp. 995-1004
    • Asseman, C.1    Mauze, S.2    Leach, M.W.3    Coffman, R.L.4    Powrie, F.5
  • 5
    • 0029956024 scopus 로고    scopus 로고
    • A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells
    • Powrie F., Carlino J., Leach M.W., Mauze S., and Coffman R.L. A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells. J Exp Med 183 (1996) 2669-2674
    • (1996) J Exp Med , vol.183 , pp. 2669-2674
    • Powrie, F.1    Carlino, J.2    Leach, M.W.3    Mauze, S.4    Coffman, R.L.5
  • 6
    • 0034679567 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
    • Read S., Malmstrom V., and Powrie F. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J Exp Med 192 (2000) 295-302
    • (2000) J Exp Med , vol.192 , pp. 295-302
    • Read, S.1    Malmstrom, V.2    Powrie, F.3
  • 7
    • 36549030784 scopus 로고    scopus 로고
    • The inhibitory cytokine IL-35 contributes to regulatory T-cell function
    • Collison L.W., Workman C.J., Kuo T.T., et al. The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature 450 (2007) 566-569
    • (2007) Nature , vol.450 , pp. 566-569
    • Collison, L.W.1    Workman, C.J.2    Kuo, T.T.3
  • 8
    • 34548463435 scopus 로고    scopus 로고
    • Expanded murine regulatory T cells: analysis of phenotype and function in contact hypersensitivity reactions
    • Ring S., Thome M., Pretsch L., Enk A.H., and Mahnke K. Expanded murine regulatory T cells: analysis of phenotype and function in contact hypersensitivity reactions. J Immunol Methods 326 (2007) 10-21
    • (2007) J Immunol Methods , vol.326 , pp. 10-21
    • Ring, S.1    Thome, M.2    Pretsch, L.3    Enk, A.H.4    Mahnke, K.5
  • 9
    • 33751238500 scopus 로고    scopus 로고
    • CD4+ CD25+ regulatory T cells suppress contact hypersensitivity reactions by blocking influx of effector T cells into inflamed tissue
    • Ring S., Schafer S.C., Mahnke K., Lehr H.A., and Enk A.H. CD4+ CD25+ regulatory T cells suppress contact hypersensitivity reactions by blocking influx of effector T cells into inflamed tissue. Eur J Immunol 36 (2006) 2981-2992
    • (2006) Eur J Immunol , vol.36 , pp. 2981-2992
    • Ring, S.1    Schafer, S.C.2    Mahnke, K.3    Lehr, H.A.4    Enk, A.H.5
  • 10
    • 34250351459 scopus 로고    scopus 로고
    • Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
    • Deaglio S., Dwyer K.M., Gao W., et al. Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J Exp Med 204 (2007) 1257-1265
    • (2007) J Exp Med , vol.204 , pp. 1257-1265
    • Deaglio, S.1    Dwyer, K.M.2    Gao, W.3
  • 11
    • 0345540629 scopus 로고    scopus 로고
    • Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation
    • Enjyoji K., Sévigny J., Lin Y., et al. Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation. Nat Med 5 (1999) 1010-1017
    • (1999) Nat Med , vol.5 , pp. 1010-1017
    • Enjyoji, K.1    Sévigny, J.2    Lin, Y.3
  • 12
    • 0032528562 scopus 로고    scopus 로고
    • CD4+ T cells migrate into inflamed skin only if they express ligands for E- and P-selectin
    • Tietz W., Allemand Y., Borges E., et al. CD4+ T cells migrate into inflamed skin only if they express ligands for E- and P-selectin. J Immunol 161 (1998) 963-970
    • (1998) J Immunol , vol.161 , pp. 963-970
    • Tietz, W.1    Allemand, Y.2    Borges, E.3
  • 13
    • 0026481133 scopus 로고
    • Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
    • Inaba K., Inaba M., Romani N., et al. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J Exp Med 176 (1992) 1693-1702
    • (1992) J Exp Med , vol.176 , pp. 1693-1702
    • Inaba, K.1    Inaba, M.2    Romani, N.3
  • 14
    • 33847492835 scopus 로고
    • Adenosine and the concept of "retaliatory metabolites"
    • Newby A.C. Adenosine and the concept of "retaliatory metabolites". Trends Biochem Sci 9 (1984) 42-44
    • (1984) Trends Biochem Sci , vol.9 , pp. 42-44
    • Newby, A.C.1
  • 15
    • 22344435384 scopus 로고    scopus 로고
    • Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel disease
    • Odashima M., Bamias G., Rivera-Nieves J., et al. Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel disease. Gastroenterology 129 (2005) 26-33
    • (2005) Gastroenterology , vol.129 , pp. 26-33
    • Odashima, M.1    Bamias, G.2    Rivera-Nieves, J.3
  • 16
    • 33747785278 scopus 로고    scopus 로고
    • Cutting edge: critical role for A2A adenosine receptors in the T cell-mediated regulation of colitis
    • Naganuma M., Wiznerowicz E.B., Lappas C.M., et al. Cutting edge: critical role for A2A adenosine receptors in the T cell-mediated regulation of colitis. J Immunol 177 (2006) 2765-2769
    • (2006) J Immunol , vol.177 , pp. 2765-2769
    • Naganuma, M.1    Wiznerowicz, E.B.2    Lappas, C.M.3
  • 17
    • 34547773217 scopus 로고    scopus 로고
    • Adenosine receptor activation ameliorates type 1 diabetes
    • Nemeth Z.H., Bleich D., Csoka B., et al. Adenosine receptor activation ameliorates type 1 diabetes. FASEB J 21 (2007) 2379-2388
    • (2007) FASEB J , vol.21 , pp. 2379-2388
    • Nemeth, Z.H.1    Bleich, D.2    Csoka, B.3
  • 18
    • 29144501467 scopus 로고    scopus 로고
    • Adenosine augments IL-10 production by macrophages through an A2B receptor-mediated posttranscriptional mechanism
    • Nemeth Z.H., Lutz C.S., Csoka B., et al. Adenosine augments IL-10 production by macrophages through an A2B receptor-mediated posttranscriptional mechanism. J Immunol 175 (2005) 8260-8270
    • (2005) J Immunol , vol.175 , pp. 8260-8270
    • Nemeth, Z.H.1    Lutz, C.S.2    Csoka, B.3
  • 19
    • 11844262735 scopus 로고    scopus 로고
    • A2A adenosine receptor induction inhibits IFN-gamma production in murine CD4+ T cells
    • Lappas C.M., Rieger J.M., and Linden J. A2A adenosine receptor induction inhibits IFN-gamma production in murine CD4+ T cells. J Immunol 174 (2005) 1073-1080
    • (2005) J Immunol , vol.174 , pp. 1073-1080
    • Lappas, C.M.1    Rieger, J.M.2    Linden, J.3
  • 20
    • 22944470530 scopus 로고    scopus 로고
    • Low-dose methotrexate: a mainstay in the treatment of rheumatoid arthritis
    • Cronstein B.N. Low-dose methotrexate: a mainstay in the treatment of rheumatoid arthritis. Pharmacol Rev 57 (2005) 163-172
    • (2005) Pharmacol Rev , vol.57 , pp. 163-172
    • Cronstein, B.N.1
  • 21
    • 34248524004 scopus 로고    scopus 로고
    • The antiinflammatory mechanism of methotrexate depends on extracellular conversion of adenine nucleotides to adenosine by ecto-5′-nucleotidase: findings in a study of ecto-5′-nucleotidase gene-deficient mice
    • Montesinos M.C., Takedachi M., Thompson L.F., et al. The antiinflammatory mechanism of methotrexate depends on extracellular conversion of adenine nucleotides to adenosine by ecto-5′-nucleotidase: findings in a study of ecto-5′-nucleotidase gene-deficient mice. Arthritis Rheum 56 (2007) 1440-1445
    • (2007) Arthritis Rheum , vol.56 , pp. 1440-1445
    • Montesinos, M.C.1    Takedachi, M.2    Thompson, L.F.3
  • 22
    • 33748357735 scopus 로고    scopus 로고
    • A2A adenosine receptor protects tumors from antitumor T cells
    • Ohta A., Gorelik E., Prasad S.J., et al. A2A adenosine receptor protects tumors from antitumor T cells. Proc Natl Acad Sci U S A 103 (2006) 13132-13137
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 13132-13137
    • Ohta, A.1    Gorelik, E.2    Prasad, S.J.3
  • 23
    • 0035021866 scopus 로고    scopus 로고
    • Complex regulation of nucleoside transporter expression in epithelial and immune system cells
    • Pastor-Anglada M., Casado F.J., Valdes R., et al. Complex regulation of nucleoside transporter expression in epithelial and immune system cells. Mol Membr Biol 18 (2001) 81-85
    • (2001) Mol Membr Biol , vol.18 , pp. 81-85
    • Pastor-Anglada, M.1    Casado, F.J.2    Valdes, R.3
  • 24
    • 34547098277 scopus 로고    scopus 로고
    • Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression
    • Borsellino G., Kleinewietfeld M., Di M.D., et al. Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression. Blood 110 (2007) 1225-1232
    • (2007) Blood , vol.110 , pp. 1225-1232
    • Borsellino, G.1    Kleinewietfeld, M.2    Di, M.D.3
  • 25
    • 41549159660 scopus 로고    scopus 로고
    • Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces
    • Rubtsov Y.P., Rasmussen J.P., Chi E.Y., et al. Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces. Immunity 28 (2008) 546-558
    • (2008) Immunity , vol.28 , pp. 546-558
    • Rubtsov, Y.P.1    Rasmussen, J.P.2    Chi, E.Y.3
  • 26
    • 33847144180 scopus 로고    scopus 로고
    • Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection
    • Jankovic D., Kullberg M.C., Feng C.G., et al. Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection. J Exp Med 204 (2007) 273-283
    • (2007) J Exp Med , vol.204 , pp. 273-283
    • Jankovic, D.1    Kullberg, M.C.2    Feng, C.G.3
  • 27
    • 33847163271 scopus 로고    scopus 로고
    • CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis
    • Anderson C.F., Oukka M., Kuchroo V.J., and Sacks D. CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis. J Exp Med 204 (2007) 285-297
    • (2007) J Exp Med , vol.204 , pp. 285-297
    • Anderson, C.F.1    Oukka, M.2    Kuchroo, V.J.3    Sacks, D.4
  • 28
    • 33749261659 scopus 로고    scopus 로고
    • Adenosine 5′-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation
    • Bours M.J., Swennen E.L., Di V.F., Cronstein B.N., and Dagnelie P.C. Adenosine 5′-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther 112 (2006) 358-404
    • (2006) Pharmacol Ther , vol.112 , pp. 358-404
    • Bours, M.J.1    Swennen, E.L.2    Di, V.F.3    Cronstein, B.N.4    Dagnelie, P.C.5
  • 30
    • 34547655975 scopus 로고    scopus 로고
    • Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells
    • Idzko M., Hammad H., van Nimwegen M., et al. Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells. Nat Med 13 (2007) 913-919
    • (2007) Nat Med , vol.13 , pp. 913-919
    • Idzko, M.1    Hammad, H.2    van Nimwegen, M.3
  • 31
    • 0036102125 scopus 로고    scopus 로고
    • CD39 is the dominant Langerhans cell-associated ecto-NTPDase: modulatory roles in inflammation and immune responsiveness
    • Mizumoto N., Kumamoto T., Robson S.C., et al. CD39 is the dominant Langerhans cell-associated ecto-NTPDase: modulatory roles in inflammation and immune responsiveness. Nat Med 8 (2002) 358-365
    • (2002) Nat Med , vol.8 , pp. 358-365
    • Mizumoto, N.1    Kumamoto, T.2    Robson, S.C.3
  • 32
    • 0242658509 scopus 로고    scopus 로고
    • Keratinocyte ATP release assay for testing skin-irritating potentials of structurally diverse chemicals
    • Mizumoto N., Mummert M.E., Shalhevet D., and Takashima A. Keratinocyte ATP release assay for testing skin-irritating potentials of structurally diverse chemicals. J Invest Dermatol 121 (2003) 1066-1072
    • (2003) J Invest Dermatol , vol.121 , pp. 1066-1072
    • Mizumoto, N.1    Mummert, M.E.2    Shalhevet, D.3    Takashima, A.4
  • 33
    • 0032547817 scopus 로고    scopus 로고
    • Neutrophil-derived 5′-adenosine monophosphate promotes endothelial barrier function via CD73-mediated conversion to adenosine and endothelial A2B receptor activation
    • Lennon P.F., Taylor C.T., Stahl G.L., and Colgan S.P. Neutrophil-derived 5′-adenosine monophosphate promotes endothelial barrier function via CD73-mediated conversion to adenosine and endothelial A2B receptor activation. J Exp Med 188 (1998) 1433-1443
    • (1998) J Exp Med , vol.188 , pp. 1433-1443
    • Lennon, P.F.1    Taylor, C.T.2    Stahl, G.L.3    Colgan, S.P.4
  • 34
    • 33748149076 scopus 로고    scopus 로고
    • Endothelial catabolism of extracellular adenosine during hypoxia: the role of surface adenosine deaminase and CD26
    • Eltzschig H.K., Faigle M., Knapp S., et al. Endothelial catabolism of extracellular adenosine during hypoxia: the role of surface adenosine deaminase and CD26. Blood 108 (2006) 1602-1610
    • (2006) Blood , vol.108 , pp. 1602-1610
    • Eltzschig, H.K.1    Faigle, M.2    Knapp, S.3
  • 35
    • 0029968687 scopus 로고    scopus 로고
    • Adenosine inhibits cytokine release and expression of adhesion molecules by activated human endothelial cells
    • Bouma M.G., van den Wildenberg F.A., and Buurman W.A. Adenosine inhibits cytokine release and expression of adhesion molecules by activated human endothelial cells. Am J Physiol Cell Physiol 270 (1996) C522-C529
    • (1996) Am J Physiol Cell Physiol , vol.270
    • Bouma, M.G.1    van den Wildenberg, F.A.2    Buurman, W.A.3
  • 36
    • 0026507232 scopus 로고
    • Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors
    • Cronstein B.N., Levin R.I., Philips M., et al. Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors. J Immunol 148 (1992) 2201-2206
    • (1992) J Immunol , vol.148 , pp. 2201-2206
    • Cronstein, B.N.1    Levin, R.I.2    Philips, M.3
  • 37
    • 0842326088 scopus 로고    scopus 로고
    • Activation of A2A adenosine receptors inhibits expression of alpha 4/beta 1 integrin (very late antigen-4) on stimulated human neutrophils
    • Sullivan G.W., Lee D.D., Ross W.G., et al. Activation of A2A adenosine receptors inhibits expression of alpha 4/beta 1 integrin (very late antigen-4) on stimulated human neutrophils. J Leukoc Biol 75 (2004) 127-134
    • (2004) J Leukoc Biol , vol.75 , pp. 127-134
    • Sullivan, G.W.1    Lee, D.D.2    Ross, W.G.3
  • 38
    • 0035117347 scopus 로고    scopus 로고
    • Effects of interleukin-10 on monocyte/endothelial cell adhesion and MMP-9/TIMP-1 secretion
    • Mostafa M.E., Chollet-Martin S., Oudghiri M., et al. Effects of interleukin-10 on monocyte/endothelial cell adhesion and MMP-9/TIMP-1 secretion. Cardiovasc Res 49 (2001) 882-890
    • (2001) Cardiovasc Res , vol.49 , pp. 882-890
    • Mostafa, M.E.1    Chollet-Martin, S.2    Oudghiri, M.3
  • 39
    • 0036745077 scopus 로고    scopus 로고
    • Interleukin-10 inhibits proinflammatory activation of endothelium in response to Borrelia burgdorferi or lipopolysaccharide but not interleukin-1 beta or tumor necrosis factor alpha
    • Lisinski T.J., and Furie M.B. Interleukin-10 inhibits proinflammatory activation of endothelium in response to Borrelia burgdorferi or lipopolysaccharide but not interleukin-1 beta or tumor necrosis factor alpha. J Leukoc Biol 72 (2002) 503-511
    • (2002) J Leukoc Biol , vol.72 , pp. 503-511
    • Lisinski, T.J.1    Furie, M.B.2
  • 40
    • 6344283049 scopus 로고    scopus 로고
    • Targeted disruption of cd73/ecto-5′-nucleotidase alters thromboregulation and augments vascular inflammatory response
    • Koszalka P., Ozuyaman B., Huo Y., et al. Targeted disruption of cd73/ecto-5′-nucleotidase alters thromboregulation and augments vascular inflammatory response. Circ Res 95 (2004) 814-821
    • (2004) Circ Res , vol.95 , pp. 814-821
    • Koszalka, P.1    Ozuyaman, B.2    Huo, Y.3
  • 41
    • 20444414184 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells impaired for intestinal homing can prevent colitis
    • Denning T.L., Kim G., and Kronenberg M. CD4+CD25+ regulatory T cells impaired for intestinal homing can prevent colitis. J Immunol 174 (2005) 7487-7491
    • (2005) J Immunol , vol.174 , pp. 7487-7491
    • Denning, T.L.1    Kim, G.2    Kronenberg, M.3
  • 42
    • 21044449573 scopus 로고    scopus 로고
    • Lymph node occupancy is required for the peripheral development of alloantigen-specific Foxp3+ regulatory T cells
    • Ochando J.C., Yopp A.C., Yang Y., et al. Lymph node occupancy is required for the peripheral development of alloantigen-specific Foxp3+ regulatory T cells. J Immunol 174 (2005) 6993-7005
    • (2005) J Immunol , vol.174 , pp. 6993-7005
    • Ochando, J.C.1    Yopp, A.C.2    Yang, Y.3
  • 43
    • 34249710939 scopus 로고    scopus 로고
    • Induction of organ-selective CD4+ regulatory T cell homing
    • Siewert C., Menning A., Dudda J., et al. Induction of organ-selective CD4+ regulatory T cell homing. Eur J Immunol 37 (2007) 978-989
    • (2007) Eur J Immunol , vol.37 , pp. 978-989
    • Siewert, C.1    Menning, A.2    Dudda, J.3
  • 44
    • 46949111560 scopus 로고    scopus 로고
    • FoxP3+ regulatory T cells maintain immune homeostasis in the skin
    • Dudda J.C., Perdue N., Bachtanian E., and Campell D.J. FoxP3+ regulatory T cells maintain immune homeostasis in the skin. J Exp Med 205 (2008) 1559-1565
    • (2008) J Exp Med , vol.205 , pp. 1559-1565
    • Dudda, J.C.1    Perdue, N.2    Bachtanian, E.3    Campell, D.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.