SB-431542, a specific inhibitor of the TGF-β type I receptor inhibits hypoxia-induced proliferation of pulmonary artery adventitial fibroblasts

Pharmazie

Volumn 71, Issue 2, 2016, Pages 94-100

  Yuan, Wendan ^a   Liu, Wei ^a   Cai, Hongjing ^a   Sun, Xuhong ^a   Yang, Dongxia ^a   Xu, Fang ^a   Jin, Changzhu ^a  

^a BINZHOU MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; CYTOKINE; HYDROXYPROLINE; OXYGEN; 1,3 DIOXOLANE DERIVATIVE; 4-(5-BENZO(1,3)DIOXOL-5-YL-4-PYRIDIN-2-YL-1H-IMIDAZOL-2-YL)BENZAMIDE; ACTA2 PROTEIN, HUMAN; ACTIN; BENZAMIDE DERIVATIVE; COLLAGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERSTITIAL COLLAGENASE; MMP1 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; TGF-BETA TYPE I RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL WALL; CELL HYPOXIA; CELL PROLIFERATION; CELL STRUCTURE; COLLAGEN SYNTHESIS; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; HYPOXIA; HYPOXIA-INDUCED PULMONARY HYPERTENSION; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LUNG FIBROBLAST; LUNG PARENCHYMA; MALE; MTT ASSAY; NONHUMAN; PROTEIN EXPRESSION; PULMONARY ARTERY ADVENTITIAL FIBROBLAST; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULAR REMODELING; ANIMAL; ANOXIA; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL CULTURE; DOWN REGULATION; DRUG EFFECTS; FIBROBLAST; METABOLISM; PATHOLOGY; PULMONARY ARTERY; SPRAGUE DAWLEY RAT;

ACTINS; ANIMALS; ANOXIA; BENZAMIDES; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN; CYTOKINES; DIOXOLES; DOWN-REGULATION; FIBROBLASTS; HYDROXYPROLINE; MALE; MATRIX METALLOPROTEINASE 1; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; PULMONARY ARTERY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA;

EID: 84961160396     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2016.5709     Document Type: Article

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