FLT1 signaling in metastasis-associated macrophages activates an inflammatory signature that promotes breast cancer metastasis

Journal of Experimental Medicine

Volumn 212, Issue 9, 2015, Pages 1433-1448

  Qian, Bin Zhi ^a,b   Zhang, Hui ^c   Li, Jiufeng ^c   He, Tianfang ^c   Yeo, Eun Jin ^d,e   Soong, Daniel Y H ^a   Carragher, Neil O ^b   Munro, Alison ^b   Chang, Alvin ^c   Bresnick, Anne R ^c   Lang, Richard A ^d,e   Pollard, Jeffrey W ^a,c  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c ALBERT EINSTEIN CANCER CENTER   (United States)

^d CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^e UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD163 ANTIGEN; CD86 ANTIGEN; COLONY STIMULATING FACTOR 1; CRE RECOMBINASE; FOCAL ADHESION KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; VASCULOTROPIN RECEPTOR 1; FLT1 PROTEIN, HUMAN; FLT1 PROTEIN, MOUSE; TUMOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOCRINE EFFECT; BREAST CARCINOMA; BREAST METASTASIS; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; GAIN OF FUNCTION MUTATION; GENE EXPRESSION; GENETIC MODEL; HETEROZYGOSITY; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; INTRACELLULAR SIGNALING; LUNG METASTASIS; MACROPHAGE ACTIVATION; METASTASIS ASSOCIATED MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; TUMOR ASSOCIATED LEUKOCYTE; TUMOR CELL INOCULATION; TUMOR GROWTH; TUMOR PROMOTION; TUMOR SEEDING; TUMOR VOLUME; ANIMAL; BREAST TUMOR; EXPERIMENTAL MAMMARY NEOPLASM; GENETICS; MACROPHAGE; METABOLISM; METASTASIS; PATHOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ANIMALS; AUTOCRINE COMMUNICATION; BREAST NEOPLASMS; FEMALE; HUMANS; MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGES; MAMMARY NEOPLASMS, ANIMAL; MICE; MICE, TRANSGENIC; NEOPLASM METASTASIS; NEOPLASM PROTEINS; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

EID: 84961145493     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20141555     Document Type: Article

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