Codon deletions in the influenza A virus PA gene generate temperature-sensitive viruses

Journal of Virology

Volumn 90, Issue 7, 2016, Pages 3684-3693

  Meyer, Léa ^a   Sausset, Alix ^a   Sedano, Laura ^a   Da Costa, Bruno ^a   Le Goffic, Ronan ^a   Delmas, Bernard ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; PA PROTEIN; PB1 PROTEIN; RNA POLYMERASE; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS SIALIDASE; CODON; LIVE VACCINE; MUTANT PROTEIN; PA PROTEIN, INFLUENZA VIRUSES; RNA DIRECTED RNA POLYMERASE; VIRAL PROTEIN; VIRUS ANTIBODY;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; BODY TEMPERATURE; CELLULAR DISTRIBUTION; CODON; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE DELETION; GENETIC TRANSCRIPTION; IN VITRO STUDY; IN VIVO STUDY; INFECTION PREVENTION; INFLUENZA A VIRUS (H1N1); LD50; MORBIDITY; MORTALITY; MOUSE; NONHUMAN; PA GENE; PATHOGENICITY; PB1 GENE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SUBUNIT; SURVIVAL; TEMPERATURE SENSITIVE MUTANT; VIRUS GENE; VIRUS REPLICATION; WEIGHT REDUCTION; ANIMAL; BAGG ALBINO MOUSE; BLOOD; DISEASE MODEL; GENETICS; GENOMIC INSTABILITY; IMMUNOLOGY; INFLUENZA A VIRUS; METABOLISM; MICROBIAL VIABILITY; ORTHOMYXOVIRUS INFECTION; PHYSIOLOGY; TEMPERATURE; VIROLOGY;

ANIMALS; ANTIBODIES, VIRAL; CODON; DISEASE MODELS, ANIMAL; FEMALE; GENOMIC INSTABILITY; INFLUENZA A VIRUS; MICE, INBRED BALB C; MICROBIAL VIABILITY; MUTANT PROTEINS; ORTHOMYXOVIRIDAE INFECTIONS; RNA REPLICASE; SEQUENCE DELETION; TEMPERATURE; VACCINES, ATTENUATED; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84960968379     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03101-15     Document Type: Article

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