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Volumn 65, Issue 9, 2016, Pages 1522-1534

The microtubule-associated protein PRC1 promotes early recurrence of hepatocellular carcinoma in association with the Wnt/β-catenin signalling pathway

Author keywords

carcinogenesis; Cell proliferation; cell signalling; hepatocellular carcinoma; liver metastases

Indexed keywords

BETA CATENIN; CELL PROTEIN; FANCONI ANEMIA PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; KINESIN; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN FANCI; PROTEIN KIF11; PROTEIN KIF23; PROTEIN REGULATOR OF CYTOKINESIS 1; SPC25 PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN; WNT3A PROTEIN; CELL CYCLE PROTEIN; PRC1 PROTEIN, HUMAN;

EID: 84960944722     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2015-310625     Document Type: Article
Times cited : (190)

References (41)
  • 1
    • 33747830764 scopus 로고    scopus 로고
    • Hepatocellular carcinoma pathogenesis: From genes to environment
    • Farazi PA, DePinho RA. Hepatocellular carcinoma pathogenesis: from genes to environment. Nat Rev Cancer 2006;6:674-87.
    • (2006) Nat Rev Cancer , vol.6 , pp. 674-687
    • Farazi, P.A.1    DePinho, R.A.2
  • 3
    • 84155178981 scopus 로고    scopus 로고
    • Benefit of initial resection of hepatocellular carcinoma followed by transplantation in case of recurrence: An intention-to-treat analysis
    • Fuks D, Dokmak S, Paradis V, et al. Benefit of initial resection of hepatocellular carcinoma followed by transplantation in case of recurrence: an intention-to-treat analysis. Hepatology 2012;55:132-40.
    • (2012) Hepatology , vol.55 , pp. 132-140
    • Fuks, D.1    Dokmak, S.2    Paradis, V.3
  • 4
    • 80053088189 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • El-Serag HB. Hepatocellular carcinoma. N Engl J Med 2011;365:1118-27.
    • (2011) N Engl J Med , vol.365 , pp. 1118-1127
    • El-Serag, H.B.1
  • 5
    • 84891551270 scopus 로고    scopus 로고
    • Recurrent hepatocellular carcinoma: It's the virus!
    • Kim WR, Gores GJ. Recurrent hepatocellular carcinoma: it's the virus!. J Clin Oncol 2013;31:3621-2.
    • (2013) J Clin Oncol , vol.31 , pp. 3621-3622
    • Kim, W.R.1    Gores, G.J.2
  • 6
    • 84929388341 scopus 로고    scopus 로고
    • ECT2 regulates the Rho/ERK signalling axis to promote early recurrence in human hepatocellular carcinoma
    • Chen J, Xia H, Zhang X, et al. ECT2 regulates the Rho/ERK signalling axis to promote early recurrence in human hepatocellular carcinoma. J Hepatol 2015;62:1287-95.
    • (2015) J Hepatol , vol.62 , pp. 1287-1295
    • Chen, J.1    Xia, H.2    Zhang, X.3
  • 7
    • 80052867878 scopus 로고    scopus 로고
    • Upregulation of Rac GTPase-activating protein 1 is significantly associated with the early recurrence of human hepatocellular carcinoma
    • Wang SM, Ooi LL, Hui KM. Upregulation of Rac GTPase-activating protein 1 is significantly associated with the early recurrence of human hepatocellular carcinoma. Clin Cancer Res 2011;17:6040-51.
    • (2011) Clin Cancer Res , vol.17 , pp. 6040-6051
    • Wang, S.M.1    Ooi, L.L.2    Hui, K.M.3
  • 8
    • 1542347695 scopus 로고    scopus 로고
    • Convergence of Wnt, beta-catenin, and cadherin pathways
    • Nelson WJ, Nusse R. Convergence of Wnt, beta-catenin, and cadherin pathways. Science 2004;303:1483-7.
    • (2004) Science , vol.303 , pp. 1483-1487
    • Nelson, W.J.1    Nusse, R.2
  • 9
    • 84861972831 scopus 로고    scopus 로고
    • Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex
    • Li VS, Ng SS, Boersema PJ, et al. Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex. Cell 2012;149:1245-56.
    • (2012) Cell , vol.149 , pp. 1245-1256
    • Li, V.S.1    Ng, S.S.2    Boersema, P.J.3
  • 10
    • 33645016188 scopus 로고    scopus 로고
    • No exit strategy? No problem: APC inhibits beta-catenin inside the nucleus
    • Xiong Y, Kotake Y. No exit strategy? No problem: APC inhibits beta-catenin inside the nucleus. Genes Dev 2006;20:637-42.
    • (2006) Genes Dev , vol.20 , pp. 637-642
    • Xiong, Y.1    Kotake, Y.2
  • 12
    • 54449083925 scopus 로고    scopus 로고
    • Molecular targeted therapies in hepatocellular carcinoma
    • Llovet JM, Bruix J. Molecular targeted therapies in hepatocellular carcinoma. Hepatology 2008;48:1312-27.
    • (2008) Hepatology , vol.48 , pp. 1312-1327
    • Llovet, J.M.1    Bruix, J.2
  • 13
    • 0034995765 scopus 로고    scopus 로고
    • Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis
    • Laurent-Puig P, Legoix P, Bluteau O, et al. Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis. Gastroenterology 2001;120:1763-73.
    • (2001) Gastroenterology , vol.120 , pp. 1763-1773
    • Laurent-Puig, P.1    Legoix, P.2    Bluteau, O.3
  • 14
    • 0037130449 scopus 로고    scopus 로고
    • Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas
    • Taniguchi K, Roberts LR, Aderca IN, et al. Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas. Oncogene 2002;21:4863-71.
    • (2002) Oncogene , vol.21 , pp. 4863-4871
    • Taniguchi, K.1    Roberts, L.R.2    Aderca, I.N.3
  • 15
    • 58149376548 scopus 로고    scopus 로고
    • Molecular mechanisms of hepatocellular carcinoma
    • Aravalli RN, Steer CJ, Cressman EN. Molecular mechanisms of hepatocellular carcinoma. Hepatology 2008;48:2047-63.
    • (2008) Hepatology , vol.48 , pp. 2047-2063
    • Aravalli, R.N.1    Steer, C.J.2    Cressman, E.N.3
  • 16
    • 10344254872 scopus 로고    scopus 로고
    • Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas
    • Colnot S, Decaens T, Niwa-Kawakita M, et al. Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas. Proc Natl Acad Sci USA 2004;101:17216-21.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 17216-17221
    • Colnot, S.1    Decaens, T.2    Niwa-Kawakita, M.3
  • 17
    • 84870555449 scopus 로고    scopus 로고
    • SOX1 functions as a tumor suppressor by antagonizing the WNT/β-catenin signaling pathway in hepatocellular carcinoma
    • Tsao CM, Yan MD, Shih YL, et al. SOX1 functions as a tumor suppressor by antagonizing the WNT/β-catenin signaling pathway in hepatocellular carcinoma. Hepatology 2012;56:2277-87.
    • (2012) Hepatology , vol.56 , pp. 2277-2287
    • Tsao, C.M.1    Yan, M.D.2    Shih, Y.L.3
  • 18
    • 84921506774 scopus 로고    scopus 로고
    • β II-Spectrin (SPTBN1) suppresses progression of hepatocellular carcinoma and Wnt signaling by regulation of Wnt inhibitor kallistatin
    • Zhi X, Lin L, Yang S, et al. βII-Spectrin (SPTBN1) suppresses progression of hepatocellular carcinoma and Wnt signaling by regulation of Wnt inhibitor kallistatin. Hepatology 2015;61:598-612.
    • (2015) Hepatology , vol.61 , pp. 598-612
    • Zhi, X.1    Lin, L.2    Yang, S.3
  • 19
    • 84904744848 scopus 로고    scopus 로고
    • Inactivation of Wnt signaling by a human antibody that recognizes the heparan sulfate chains of glypican-3 for liver cancer therapy
    • Gao W, Kim H, Feng M, et al. Inactivation of Wnt signaling by a human antibody that recognizes the heparan sulfate chains of glypican-3 for liver cancer therapy. Hepatology 2014;60:576-87.
    • (2014) Hepatology , vol.60 , pp. 576-587
    • Gao, W.1    Kim, H.2    Feng, M.3
  • 20
    • 0033536185 scopus 로고    scopus 로고
    • Beta-catenin mutations in hepatocellular carcinoma correlate with a low rate of loss of heterozygosity
    • Legoix P, Bluteau O, Bayer J, et al. Beta-catenin mutations in hepatocellular carcinoma correlate with a low rate of loss of heterozygosity. Oncogene 1999;18:4044-6.
    • (1999) Oncogene , vol.18 , pp. 4044-4046
    • Legoix, P.1    Bluteau, O.2    Bayer, J.3
  • 21
    • 34547116880 scopus 로고    scopus 로고
    • Modulation of the microtubule cytoskeleton: A role for a divergent canonical Wnt pathway
    • Salinas PC. Modulation of the microtubule cytoskeleton: a role for a divergent canonical Wnt pathway. Trends Cell Biol 2007;17:333-42.
    • (2007) Trends Cell Biol , vol.17 , pp. 333-342
    • Salinas, P.C.1
  • 22
    • 0032252037 scopus 로고    scopus 로고
    • PRC1: A human mitotic spindle-associated CDK substrate protein required for cytokinesis
    • Jiang W, Jimenez G, Wells NJ, et al. PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis. Mol Cell 1998;2:877-85.
    • (1998) Mol Cell , vol.2 , pp. 877-885
    • Jiang, W.1    Jimenez, G.2    Wells, N.J.3
  • 23
    • 77955322029 scopus 로고    scopus 로고
    • Insights into antiparallel microtubule crosslinking by PRC1, a conserved nonmotor microtubule binding protein
    • Subramanian R, Wilson-Kubalek EM, Arthur CP, et al. Insights into antiparallel microtubule crosslinking by PRC1, a conserved nonmotor microtubule binding protein. Cell 2010;142:433-43.
    • (2010) Cell , vol.142 , pp. 433-443
    • Subramanian, R.1    Wilson-Kubalek, E.M.2    Arthur, C.P.3
  • 24
    • 84880565937 scopus 로고    scopus 로고
    • Marking and measuring single microtubules by PRC1 and kinesin-4
    • Subramanian R, Ti SC, Tan L, et al. Marking and measuring single microtubules by PRC1 and kinesin-4. Cell 2013;154:377-90.
    • (2013) Cell , vol.154 , pp. 377-390
    • Subramanian, R.1    Ti, S.C.2    Tan, L.3
  • 25
    • 79957987053 scopus 로고    scopus 로고
    • Proteomic screening of anaerobically regulated promoters from Salmonella and its antitumor applications
    • Chen J, Wei D, Zhuang H, et al. Proteomic screening of anaerobically regulated promoters from Salmonella and its antitumor applications. Mol Cell Proteomics 2011;10:M111.
    • (2011) Mol Cell Proteomics , vol.10 , pp. M111
    • Chen, J.1    Wei, D.2    Zhuang, H.3
  • 26
    • 19944422429 scopus 로고    scopus 로고
    • Differential roles for the coactivators CBP and p300 on TCF/beta-catenin-mediated survivin gene expression
    • Ma H, Nguyen C, Lee KS, et al. Differential roles for the coactivators CBP and p300 on TCF/beta-catenin-mediated survivin gene expression. Oncogene 2005;24:3619-31.
    • (2005) Oncogene , vol.24 , pp. 3619-3631
    • Ma, H.1    Nguyen, C.2    Lee, K.S.3
  • 27
    • 0345006147 scopus 로고    scopus 로고
    • Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas
    • de La CA, Romagnolo B, Billuart P, et al. Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas. Proc Natl Acad Sci USA 1998;95:8847-51.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8847-8851
    • De La, C.A.1    Romagnolo, B.2    Billuart, P.3
  • 28
    • 70349695861 scopus 로고    scopus 로고
    • Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
    • Huang SM, Mishina YM, Liu S, et al. Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature 2009;461:614-20.
    • (2009) Nature , vol.461 , pp. 614-620
    • Huang, S.M.1    Mishina, Y.M.2    Liu, S.3
  • 29
    • 84877156945 scopus 로고    scopus 로고
    • Cancer stem cells in the development of liver cancer
    • Yamashita T, Wang XW. Cancer stem cells in the development of liver cancer. J Clin Invest 2013;123:1911-18.
    • (2013) J Clin Invest , vol.123 , pp. 1911-1918
    • Yamashita, T.1    Wang, X.W.2
  • 30
    • 84880515015 scopus 로고    scopus 로고
    • TRIB2 acts downstream of Wnt/TCF in liver cancer cells to regulate YAP and C/EBPα function
    • Wang J, Park JS, Wei Y, et al. TRIB2 acts downstream of Wnt/TCF in liver cancer cells to regulate YAP and C/EBPα function. Mol Cell 2013;51:211-25.
    • (2013) Mol Cell , vol.51 , pp. 211-225
    • Wang, J.1    Park, J.S.2    Wei, Y.3
  • 31
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006;127:469-80.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 32
    • 84861986053 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling and disease
    • Clevers H, Nusse R. Wnt/β-catenin signaling and disease. Cell 2012;149:1192-205.
    • (2012) Cell , vol.149 , pp. 1192-1205
    • Clevers, H.1    Nusse, R.2
  • 33
    • 77149158796 scopus 로고    scopus 로고
    • Characterisation of the liver progenitor cell niche in liver diseases: Potential involvement of Wnt and Notch signalling
    • Spee B, Carpino G, Schotanus BA, et al. Characterisation of the liver progenitor cell niche in liver diseases: potential involvement of Wnt and Notch signalling. Gut 2010;59:247-57.
    • (2010) Gut , vol.59 , pp. 247-257
    • Spee, B.1    Carpino, G.2    Schotanus, B.A.3
  • 34
    • 84898767802 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Clinical frontiers and perspectives
    • Bruix J, Gores GJ, Mazzaferro V. Hepatocellular carcinoma: clinical frontiers and perspectives. Gut 2014;63:844-55.
    • (2014) Gut , vol.63 , pp. 844-855
    • Bruix, J.1    Gores, G.J.2    Mazzaferro, V.3
  • 35
    • 73949099275 scopus 로고    scopus 로고
    • Nuclear beta-catenin induces an early liver progenitor phenotype in hepatocellular carcinoma and promotes tumor recurrence
    • Zulehner G, Mikula M, Schneller D, et al. Nuclear beta-catenin induces an early liver progenitor phenotype in hepatocellular carcinoma and promotes tumor recurrence. Am J Pathol 2010;176:472-81.
    • (2010) Am J Pathol , vol.176 , pp. 472-481
    • Zulehner, G.1    Mikula, M.2    Schneller, D.3
  • 36
    • 84867161026 scopus 로고    scopus 로고
    • Oncogenic activation of glypican-3 by c-Myc in human hepatocellular carcinoma
    • Li L, Jin R, Zhang X, et al. Oncogenic activation of glypican-3 by c-Myc in human hepatocellular carcinoma. Hepatology 2012;56:1380-90.
    • (2012) Hepatology , vol.56 , pp. 1380-1390
    • Li, L.1    Jin, R.2    Zhang, X.3
  • 37
    • 0036890030 scopus 로고    scopus 로고
    • Prognostic significance of c-myc and AIB1 amplification in hepatocellular carcinoma. A broad survey using high-throughput tissue microarray
    • Wang Y, Wu MC, Sham JS, et al. Prognostic significance of c-myc and AIB1 amplification in hepatocellular carcinoma. A broad survey using high-throughput tissue microarray. Cancer 2002;95:2346-52.
    • (2002) Cancer , vol.95 , pp. 2346-2352
    • Wang, Y.1    Wu, M.C.2    Sham, J.S.3
  • 38
    • 34347385893 scopus 로고    scopus 로고
    • Cholestasis is a marker for hepatocellular carcinomas displaying beta-catenin mutations
    • Audard V, Grimber G, Elie C, et al. Cholestasis is a marker for hepatocellular carcinomas displaying beta-catenin mutations. J Pathol 2007;212:345-52.
    • (2007) J Pathol , vol.212 , pp. 345-352
    • Audard, V.1    Grimber, G.2    Elie, C.3
  • 39
    • 70349739285 scopus 로고    scopus 로고
    • Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma
    • Hoshida Y, Nijman SM, Kobayashi M, et al. Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma. Cancer Res 2009;69:7385-92.
    • (2009) Cancer Res , vol.69 , pp. 7385-7392
    • Hoshida, Y.1    Nijman, S.M.2    Kobayashi, M.3
  • 40
    • 33746058994 scopus 로고    scopus 로고
    • The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway
    • Chen HJ, Lin CM, Lin CS, et al. The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway. Genes Dev 2006;20:1933-45.
    • (2006) Genes Dev , vol.20 , pp. 1933-1945
    • Chen, H.J.1    Lin, C.M.2    Lin, C.S.3
  • 41
    • 70349437416 scopus 로고    scopus 로고
    • Kinesin superfamily motor proteins and intracellular transport
    • Hirokawa N, Noda Y, Tanaka Y, et al. Kinesin superfamily motor proteins and intracellular transport. Nat Rev Mol Cell Biol 2009;10:682-96.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 682-696
    • Hirokawa, N.1    Noda, Y.2    Tanaka, Y.3


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