-
2
-
-
36849028626
-
Lucifer's labyrinth - Ten years of path finding in cell death
-
Meier, P. & Vousden, K. H. Lucifer's labyrinth - ten years of path finding in cell death. Mol. Cell 28, 746-754 (2007).
-
(2007)
Mol. Cell
, vol.28
, pp. 746-754
-
-
Meier, P.1
Vousden, K.H.2
-
3
-
-
79959870486
-
Apoptotic and non-apoptotic caspase functions in neural development
-
Miura, M. Apoptotic and non-apoptotic caspase functions in neural development. Neurochem. Res. 36, 1253-1260 (2011).
-
(2011)
Neurochem. Res.
, vol.36
, pp. 1253-1260
-
-
Miura, M.1
-
4
-
-
81055125652
-
Programmed cell death in animal development and disease
-
Fuchs, Y. & Steller, H. Programmed cell death in animal development and disease. Cell 147, 742-758 (2011).
-
(2011)
Cell
, vol.147
, pp. 742-758
-
-
Fuchs, Y.1
Steller, H.2
-
5
-
-
33847367323
-
Nonapoptotic functions of caspases: Caspases as regulatory molecules for immunity and cell-fate determination
-
Kuranaga, E. & Miura, M. Nonapoptotic functions of caspases: caspases as regulatory molecules for immunity and cell-fate determination. Trends Cell Biol. 17, 135-144 (2007).
-
(2007)
Trends Cell Biol.
, vol.17
, pp. 135-144
-
-
Kuranaga, E.1
Miura, M.2
-
6
-
-
69249100500
-
Human caspases: Activation, specificity, and regulation
-
Pop, C. & Salvesen, G. S. Human caspases: activation, specificity, and regulation. J. Biol. Chem. 284, 21777-21781 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 21777-21781
-
-
Pop, C.1
Salvesen, G.S.2
-
7
-
-
84919934365
-
Usher syndrome: Hearing loss, retinal degeneration and associated abnormalities
-
Mathur, P. & Yang, J. Usher syndrome: hearing loss, retinal degeneration and associated abnormalities. Biochim. Biophys. Acta 1852, 406-420 (2015).
-
(2015)
Biochim. Biophys. Acta
, vol.1852
, pp. 406-420
-
-
Mathur, P.1
Yang, J.2
-
8
-
-
38749124706
-
Usher syndrome: Animal models, retinal function of Usher proteins, and prospects for gene therapy
-
Williams, D. S. Usher syndrome: animal models, retinal function of Usher proteins, and prospects for gene therapy. Vision Res. 48, 433-441 (2008).
-
(2008)
Vision Res.
, vol.48
, pp. 433-441
-
-
Williams, D.S.1
-
9
-
-
10844264543
-
Drosophila crinkled, mutations of which disrupt morphogenesis and cause lethality, encodes fly myosin VIIA
-
Kiehart, D. P. et al. Drosophila crinkled, mutations of which disrupt morphogenesis and cause lethality, encodes fly myosin VIIA. Genetics 168, 1337-1352 (2004).
-
(2004)
Genetics
, vol.168
, pp. 1337-1352
-
-
Kiehart, D.P.1
-
10
-
-
0034704098
-
An essential role for the caspase dronc in developmentally programmed cell death in Drosophila
-
Quinn, L. M. et al. An essential role for the caspase dronc in developmentally programmed cell death in Drosophila. J. Biol. Chem. 275, 40416-40424 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 40416-40424
-
-
Quinn, L.M.1
-
11
-
-
0034651987
-
The Drosophila caspase DRONC is regulated by DIAP1
-
Meier, P., Silke, J., Leevers, S. J. & Evan, G. I. The Drosophila caspase DRONC is regulated by DIAP1. EMBO J. 19, 598-611 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 598-611
-
-
Meier, P.1
Silke, J.2
Leevers, S.J.3
Evan, G.I.4
-
12
-
-
0034282666
-
The Drosophila caspase DRONC cleaves following glutamate or aspartate and is regulated by DIAP1, HID, and GRIM
-
Hawkins, C. J., Yoo, S. J., Peterson, E. P., Wang, S. L., Vernooy, S. Y. & Hay, B. A. The Drosophila caspase DRONC cleaves following glutamate or aspartate and is regulated by DIAP1, HID, and GRIM. J. Biol. Chem. 275, 27084-27093 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 27084-27093
-
-
Hawkins, C.J.1
Yoo, S.J.2
Peterson, E.P.3
Wang, S.L.4
Vernooy, S.Y.5
Hay, B.A.6
-
13
-
-
0034651791
-
Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function
-
Goyal, L., McCall, K., Agapite, J., Hartwieg, E. & Steller, H. Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function. EMBO J. 19, 589-597 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 589-597
-
-
Goyal, L.1
McCall, K.2
Agapite, J.3
Hartwieg, E.4
Steller, H.5
-
14
-
-
0033588273
-
The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID
-
Wang, S. L., Hawkins, C. J., Yoo, S. J., Muller, H. A. & Hay, B. A. The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID. Cell 98, 453-463 (1999).
-
(1999)
Cell
, vol.98
, pp. 453-463
-
-
Wang, S.L.1
Hawkins, C.J.2
Yoo, S.J.3
Muller, H.A.4
Hay, B.A.5
-
15
-
-
0031738898
-
Distinct cell killing properties of the Drosophila reaper, head involution defective, and grim genes
-
Wing, J. P., Zhou, L., Schwartz, L. M. & Nambu, J. R. Distinct cell killing properties of the Drosophila reaper, head involution defective, and grim genes. Cell Death Differ. 5, 930-939 (1998).
-
(1998)
Cell Death Differ.
, vol.5
, pp. 930-939
-
-
Wing, J.P.1
Zhou, L.2
Schwartz, L.M.3
Nambu, J.R.4
-
16
-
-
0032582662
-
The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling
-
Bergmann, A., Agapite, J., McCall, K. & Steller, H. The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling. Cell 95, 331-341 (1998).
-
(1998)
Cell
, vol.95
, pp. 331-341
-
-
Bergmann, A.1
Agapite, J.2
McCall, K.3
Steller, H.4
-
17
-
-
0029161958
-
The head involution defective gene of Drosophila melanogaster functions in programmed cell death
-
Grether, M. E., Abrams, J. M., Agapite, J., White, K. & Steller, H. The head involution defective gene of Drosophila melanogaster functions in programmed cell death. Genes Dev. 9, 1694-1708 (1995).
-
(1995)
Genes Dev.
, vol.9
, pp. 1694-1708
-
-
Grether, M.E.1
Abrams, J.M.2
Agapite, J.3
White, K.4
Steller, H.5
-
18
-
-
19444366944
-
The CARD-carrying caspase Dronc is essential for most, but not all, developmental cell death in Drosophila
-
Xu, D., Li, Y., Arcaro, M., Lackey, M. & Bergmann, A. The CARD-carrying caspase Dronc is essential for most, but not all, developmental cell death in Drosophila. Development 132, 2125-2134 (2005).
-
(2005)
Development
, vol.132
, pp. 2125-2134
-
-
Xu, D.1
Li, Y.2
Arcaro, M.3
Lackey, M.4
Bergmann, A.5
-
19
-
-
34447628492
-
The Drosophila caspases Strica and Dronc function redundantly in programmed cell death during oogenesis
-
Baum, J. S., Arama, E., Steller, H. & McCall, K. The Drosophila caspases Strica and Dronc function redundantly in programmed cell death during oogenesis. Cell Death Differ. 14, 1508-1517 (2007).
-
(2007)
Cell Death Differ.
, vol.14
, pp. 1508-1517
-
-
Baum, J.S.1
Arama, E.2
Steller, H.3
McCall, K.4
-
20
-
-
33746570157
-
Drosophila IKK-related kinase regulates nonapoptotic function of caspases via degradation of IAPs
-
Kuranaga, E. et al. Drosophila IKK-related kinase regulates nonapoptotic function of caspases via degradation of IAPs. Cell 126, 583-596 (2006).
-
(2006)
Cell
, vol.126
, pp. 583-596
-
-
Kuranaga, E.1
-
21
-
-
33746574519
-
IKK epsilon regulates F actin assembly and interacts with Drosophila IAP1 in cellular morphogenesis
-
Oshima, K. et al. IKK epsilon regulates F actin assembly and interacts with Drosophila IAP1 in cellular morphogenesis. Curr. Biol. 16, 1531-1537 (2006).
-
(2006)
Curr. Biol.
, vol.16
, pp. 1531-1537
-
-
Oshima, K.1
-
22
-
-
4644350173
-
Role of programmed cell death in patterning the Drosophila antennal arista
-
Cullen, K. & McCall, K. Role of programmed cell death in patterning the Drosophila antennal arista. Dev. Biol. 275, 82-92 (2004).
-
(2004)
Dev. Biol.
, vol.275
, pp. 82-92
-
-
Cullen, K.1
McCall, K.2
-
23
-
-
0025990093
-
The beginning of pattern formation in the Drosophila compound eye: The morphogenetic furrow and the second mitotic wave
-
Wolff, T. & Ready, D. F. The beginning of pattern formation in the Drosophila compound eye: the morphogenetic furrow and the second mitotic wave. Development 113, 841-850 (1991).
-
(1991)
Development
, vol.113
, pp. 841-850
-
-
Wolff, T.1
Ready, D.F.2
-
24
-
-
33749521656
-
Cytochrome c-d regulates developmental apoptosis in the Drosophila retina
-
Mendes, C. S. et al. Cytochrome c-d regulates developmental apoptosis in the Drosophila retina. EMBO Rep. 7, 933-939 (2006).
-
(2006)
EMBO Rep.
, vol.7
, pp. 933-939
-
-
Mendes, C.S.1
-
25
-
-
0032440288
-
Mechanisms and control of programmed cell death in invertebrates
-
Bergmann, A., Agapite, J. & Steller, H. Mechanisms and control of programmed cell death in invertebrates. Oncogene 17, 3215-3223 (1998).
-
(1998)
Oncogene
, vol.17
, pp. 3215-3223
-
-
Bergmann, A.1
Agapite, J.2
Steller, H.3
-
26
-
-
0027453109
-
Programmed cell death during Drosophila embryogenesis
-
Abrams, J. M., White, K., Fessler, L. I. & Steller, H. Programmed cell death during Drosophila embryogenesis. Development 117, 29-43 (1993).
-
(1993)
Development
, vol.117
, pp. 29-43
-
-
Abrams, J.M.1
White, K.2
Fessler, L.I.3
Steller, H.4
-
27
-
-
27744511564
-
Drosophila caspase transduces Shaggy/GSK-3beta kinase activity in neural precursor development
-
Kanuka, H. et al. Drosophila caspase transduces Shaggy/GSK-3beta kinase activity in neural precursor development. EMBO J. 24, 3793-3806 (2005).
-
(2005)
EMBO J.
, vol.24
, pp. 3793-3806
-
-
Kanuka, H.1
-
28
-
-
18944408058
-
Myosin VIIA defects, which underlie the Usher 1B syndrome in humans, lead to deafness in Drosophila
-
Todi, S. V., Franke, J. D., Kiehart, D. P. & Eberl, D. F. Myosin VIIA defects, which underlie the Usher 1B syndrome in humans, lead to deafness in Drosophila. Curr. Biol. 15, 862-868 (2005).
-
(2005)
Curr. Biol.
, vol.15
, pp. 862-868
-
-
Todi, S.V.1
Franke, J.D.2
Kiehart, D.P.3
Eberl, D.F.4
-
29
-
-
3142598843
-
A role for Drosophila IAP1-mediated caspase inhibition in Rac-dependent cell migration
-
Geisbrecht, E. R. & Montell, D. J. A role for Drosophila IAP1-mediated caspase inhibition in Rac-dependent cell migration. Cell 118, 111-125 (2004).
-
(2004)
Cell
, vol.118
, pp. 111-125
-
-
Geisbrecht, E.R.1
Montell, D.J.2
-
30
-
-
79952761364
-
Drosophila Ras/MAPK signalling regulates innate immune responses in immune and intestinal stem cells
-
Ragab, A., Buechling, T., Gesellchen, V., Spirohn, K., Boettcher, A. L. & Boutros, M. Drosophila Ras/MAPK signalling regulates innate immune responses in immune and intestinal stem cells. EMBO J. 30, 1123-1136 (2011).
-
(2011)
EMBO J.
, vol.30
, pp. 1123-1136
-
-
Ragab, A.1
Buechling, T.2
Gesellchen, V.3
Spirohn, K.4
Boettcher, A.L.5
Boutros, M.6
-
31
-
-
84900444834
-
Complexes of Usher proteins preassemble at the endoplasmic reticulum and are required for trafficking and ER homeostasis
-
Blanco-Sanchez, B., Clement, A., Fierro, Jr J., Washbourne, P. &Westerfield, M. Complexes of Usher proteins preassemble at the endoplasmic reticulum and are required for trafficking and ER homeostasis. Dis. Model Mech. 7, 547-559 (2014).
-
(2014)
Dis. Model Mech.
, vol.7
, pp. 547-559
-
-
Blanco-Sanchez, B.1
Clement, A.2
Fierro, J.3
Washbourne, P.4
Westerfield, M.5
-
32
-
-
33751252292
-
Direct observation of individual endogenous protein complexes in situ by proximity ligation
-
Soderberg, O. et al. Direct observation of individual endogenous protein complexes in situ by proximity ligation. Nat. Methods 3, 995-1000 (2006).
-
(2006)
Nat. Methods
, vol.3
, pp. 995-1000
-
-
Soderberg, O.1
-
33
-
-
79960921946
-
The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs
-
Tenev, T. et al. The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs. Mol. Cell 43, 432-448 (2011).
-
(2011)
Mol. Cell
, vol.43
, pp. 432-448
-
-
Tenev, T.1
-
34
-
-
79960922705
-
CIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms
-
Feoktistova, M. et al. cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms. Mol. Cell 43, 449-463 (2011).
-
(2011)
Mol. Cell
, vol.43
, pp. 449-463
-
-
Feoktistova, M.1
-
35
-
-
43049152912
-
TNF-alpha induces two distinct caspase-8 activation pathways
-
Wang, L., Du, F. & Wang, X. TNF-alpha induces two distinct caspase-8 activation pathways. Cell 133, 693-703 (2008).
-
(2008)
Cell
, vol.133
, pp. 693-703
-
-
Wang, L.1
Du, F.2
Wang, X.3
-
36
-
-
0347065342
-
A role for tumor necrosis factor receptor-2 and receptorinteracting protein in programmed necrosis and antiviral responses
-
Chan, F. K. et al. A role for tumor necrosis factor receptor-2 and receptorinteracting protein in programmed necrosis and antiviral responses. J. Biol. Chem. 278, 51613-51621 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 51613-51621
-
-
Chan, F.K.1
-
37
-
-
0033214236
-
Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis
-
Lin, Y., Devin, A., Rodriguez, Y. & Liu, Z. G. Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev. 13, 2514-2526 (1999).
-
(1999)
Genes Dev.
, vol.13
, pp. 2514-2526
-
-
Lin, Y.1
Devin, A.2
Rodriguez, Y.3
Liu, Z.G.4
-
38
-
-
79952810024
-
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
-
Oberst, A. et al. Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature 471, 363-367 (2011).
-
(2011)
Nature
, vol.471
, pp. 363-367
-
-
Oberst, A.1
-
39
-
-
80053580530
-
RIPK-dependent necrosis and its regulation by caspases: A mystery in five acts
-
Green, D. R., Oberst, A., Dillon, C. P., Weinlich, R. & Salvesen, G. S. RIPK-dependent necrosis and its regulation by caspases: a mystery in five acts. Mol. Cell 44, 9-16 (2011).
-
(2011)
Mol. Cell
, vol.44
, pp. 9-16
-
-
Green, D.R.1
Oberst, A.2
Dillon, C.P.3
Weinlich, R.4
Salvesen, G.S.5
-
40
-
-
84875138006
-
Inhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammation
-
Silke, J. & Meier, P. Inhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammation. Cold Spring Harb. Perspect. Biol. 5 (2013).
-
(2013)
Cold Spring Harb. Perspect. Biol.
, vol.5
-
-
Silke, J.1
Meier, P.2
-
41
-
-
80054852212
-
TNF and ubiquitin at the crossroads of gene activation, cell death, inflammation, and cancer
-
Walczak, H. TNF and ubiquitin at the crossroads of gene activation, cell death, inflammation, and cancer. Immunol. Rev. 244, 9-28 (2011).
-
(2011)
Immunol. Rev.
, vol.244
, pp. 9-28
-
-
Walczak, H.1
-
42
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
Micheau, O. & Tschopp, J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114, 181-190 (2003).
-
(2003)
Cell
, vol.114
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
43
-
-
67349162130
-
Tumour necrosis factor and cancer
-
Balkwill, F. Tumour necrosis factor and cancer. Nat. Rev. Cancer 9, 361-371 (2009).
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 361-371
-
-
Balkwill, F.1
-
44
-
-
84922602504
-
Necroptosis and its role in inflammation
-
Pasparakis, M. & Vandenabeele, P. Necroptosis and its role in inflammation. Nature 517, 311-320 (2015).
-
(2015)
Nature
, vol.517
, pp. 311-320
-
-
Pasparakis, M.1
Vandenabeele, P.2
-
45
-
-
84878105372
-
Contribution of TNF-alpha to the development of retinal neurodegenerative disorders
-
Al-Gayyar, M. M. & Elsherbiny, N. M. Contribution of TNF-alpha to the development of retinal neurodegenerative disorders. Eur. Cytokine Netw. 24, 27-36 (2013).
-
(2013)
Eur. Cytokine Netw.
, vol.24
, pp. 27-36
-
-
Al-Gayyar, M.M.1
Elsherbiny, N.M.2
-
46
-
-
80053342176
-
The many different cellular functions of MYO7A in the retina
-
Williams, D. S. & Lopes, V. S. The many different cellular functions of MYO7A in the retina. Biochem. Soc. Trans. 39, 1207-1210 (2011).
-
(2011)
Biochem. Soc. Trans.
, vol.39
, pp. 1207-1210
-
-
Williams, D.S.1
Lopes, V.S.2
-
47
-
-
84864318803
-
A death effector domain chain DISC model reveals a crucial role for caspase-8 chain assembly in mediating apoptotic cell death
-
Dickens, L. S. et al. A death effector domain chain DISC model reveals a crucial role for caspase-8 chain assembly in mediating apoptotic cell death. Mol. Cell 47, 291-305 (2012).
-
(2012)
Mol. Cell
, vol.47
, pp. 291-305
-
-
Dickens, L.S.1
|