Activation of GPER suppresses epithelial mesenchymal transition of triple negative breast cancer cells via NF-κB signals

Molecular Oncology

Volumn 10, Issue 6, 2016, Pages 775-788

  Chen, Zhuo Jia ^a   Wei, Wei ^b   Jiang, Guan Min ^c   Liu, Hao ^d   Wei, Wei Dong ^a   Yang, Xiangling ^b   Wu, Ying Min ^b   Liu, Huanliang ^b   Wong, Chris K C ^e   Du, Jun ^b   Wang, Hong Sheng ^b  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c CENTRAL SOUTH UNIVERSITY   (China)

^d GUANGZHOU MEDICAL UNIVERSITY   (China)

^e HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

Author keywords

EMT; G 1; GPER; NF B; TNBC

Indexed keywords

ANTINEOPLASTIC AGENT; FIBRONECTIN; G PROTEIN COUPLED ESTROGEN RECEPTOR 30 AGONIST; G PROTEIN COUPLED RECEPTOR 30; GLYCOGEN SYNTHASE KINASE 3BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; ESTROGEN RECEPTOR; G PROTEIN COUPLED RECEPTOR; GPER PROTEIN, HUMAN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL LINE; CANCER INHIBITION; CANCER PROGNOSIS; CANCER SPECIFIC SURVIVAL; CELL INVASION; CELL MIGRATION; CELL NUCLEUS; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EFFECT; DRUG MECHANISM; DRUG TARGETING; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRIPLE NEGATIVE BREAST CANCER; TUMOR XENOGRAFT; ANIMAL; BREAST; CELL MOTION; GENE EXPRESSION REGULATION; GENETICS; MAPK SIGNALING; METABOLISM; MIDDLE AGED; NUDE MOUSE; PATHOLOGY; PHOSPHORYLATION; TUMOR CELL LINE;

ANIMALS; BREAST; CELL LINE, TUMOR; CELL MOVEMENT; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; FIBRONECTINS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOGEN SYNTHASE KINASE 3 BETA; HUMANS; MAP KINASE SIGNALING SYSTEM; MICE, NUDE; MIDDLE AGED; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, ESTROGEN; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; TRIPLE NEGATIVE BREAST NEOPLASMS;

EID: 84960830547     PISSN: 15747891     EISSN: 18780261     Source Type: Journal    
DOI: 10.1016/j.molonc.2016.01.002     Document Type: Article

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