Search for the potential "second-hit" mechanism underlying the onset of familial hemophagocytic lymphohistiocytosis type 2 by whole-exome sequencing analysis

Translational Research

Volumn 170, Issue , 2016, Pages 26-39

  Gao, Lili ^a   Dang, Xiao ^b,c   Huang, Liang ^a   Zhu, Li ^a   Fang, Mingyan ^c   Zhang, Jianguo ^c   Xu, Xun ^c   Zhu, Lijun ^a   Li, Tongjuan ^a   Zhao, Lei ^a   Wei, Jia ^a   Zhou, Jianfeng ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c BGI SHENZHEN   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CD2 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD5 ANTIGEN; CD7 ANTIGEN; CD8 ANTIGEN; FERRITIN; FIBRINOGEN; HEMOGLOBIN; LACTATE DEHYDROGENASE; LEUKOSIALIN; PERFORIN; PROTEIN; PROTEIN PCDH18; UNCLASSIFIED DRUG; CADHERIN; PCDH18 PROTEIN, HUMAN; PRF1 PROTEIN, HUMAN;

ADULT; APOPTOSIS; ARTICLE; AXILLARY LYMPH NODE; CASE REPORT; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; EPSTEIN BARR VIRUS INFECTION; FAMILIAL HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS TYPE 2; FEMALE; FERRITIN BLOOD LEVEL; FEVER; FRAMESHIFT MUTATION; GENE SEQUENCE; GERMLINE MUTATION; HEMOPHAGOCYTIC SYNDROME; HETEROZYGOTE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERPLASIA; LACTATE DEHYDROGENASE BLOOD LEVEL; LYMPHADENOPATHY; LYMPHOMA; MISSENSE MUTATION; NEXT GENERATION SEQUENCING; PLEURA EFFUSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; SOMATIC MUTATION; SPLENECTOMY; TARGET CELL; YOUNG ADULT; EXOME; GENETICS; HIGH THROUGHPUT SEQUENCING; IMMUNOLOGY; MALE; MUTATION; NATURAL KILLER CELL; PATHOLOGY; PHYSIOLOGY; VIROLOGY;

ADULT; CADHERINS; CD8-POSITIVE T-LYMPHOCYTES; EPSTEIN-BARR VIRUS INFECTIONS; EXOME; FEMALE; GERM-LINE MUTATION; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; KILLER CELLS, NATURAL; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; MALE; MUTATION; MUTATION, MISSENSE; PERFORIN;

EID: 84960801029     PISSN: 19315244     EISSN: 18781810     Source Type: Journal    
DOI: 10.1016/j.trsl.2015.12.004     Document Type: Article

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