Synergistic defects of different molecules in the cytotoxic pathway lead to clinical familial hemophagocytic lymphohistiocytosis

Blood

Volumn 124, Issue 8, 2014, Pages 1331-1334

  Zhang, Kejian ^a   Chandrakasan, Shanmuganathan ^a   Chapman, Heather ^a   Valencia, C Alexander ^a   Husami, Ammar ^a   Kissell, Diane ^a   Johnson, Judith A ^a   Filipovich, Alexandra H ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MUCIN 13; PERFORIN; PROTEIN; RAB27A PROTEIN; STXBP2 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CYTOTOXIC LYMPHOCYTE; DEGRANULATION; GENE MUTATION; HEMOPHAGOCYTIC SYNDROME; HETEROZYGOSITY; HETEROZYGOTE; HUMAN; INHERITANCE; MAJOR CLINICAL STUDY; MEDICAL RECORD REVIEW; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROSPECTIVE STUDY;

ADOLESCENT; ADULT; CELL DEGRANULATION; CHILD; CHILD, PRESCHOOL; EPISTASIS, GENETIC; FEMALE; HUMANS; INFANT; LYMPHOCYTES; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 1; MALE; MODELS, GENETIC; MUTATION; PORE FORMING CYTOTOXIC PROTEINS; RETROSPECTIVE STUDIES;

EID: 84907348494     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-05-573105     Document Type: Article

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