Structure of glycosylated NPC1 luminal domain C reveals insights into NPC2 and Ebola virus interactions

FEBS Letters

Volumn 590, Issue 5, 2016, Pages 605-612

  Zhao, Yuguang ^a   Ren, Jingshan ^a   Harlos, Karl ^a   Stuart, David I ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b DIAMOND LIGHT SOURCE LTD   (United Kingdom)

Author keywords

cholesterol transport; Ebola virus receptor; Ebola virus susceptibility; Niemann Pick disease type C; NPC1; NPC2

Indexed keywords

MEMBRANE PROTEIN; NIEMANN PICK TYPE C1; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN; CARRIER PROTEIN; GLYCOPROTEIN; NPC1 PROTEIN, HUMAN; NPC2 PROTEIN, HUMAN; PROTEIN BINDING;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; EBOLAVIRUS; FILOVIRUS; MOLECULAR DOCKING; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN GLYCOSYLATION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RESIDUE ANALYSIS; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; GLYCOSYLATION; HEK293 CELL LINE; HUMAN; METABOLISM; MOLECULAR GENETICS; MOLECULAR MODEL; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; CARRIER PROTEINS; EBOLAVIRUS; GLYCOPROTEINS; GLYCOSYLATION; HEK293 CELLS; HUMANS; MEMBRANE GLYCOPROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

EID: 84960797910     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1002/1873-3468.12089     Document Type: Article

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