Plasmin cleaves fibrinogen and the human complement proteins C3b and C5 in the presence of Leptospira interrogans proteins: A new role of LigA and LigB in invasion and complement immune evasion

Immunobiology

Volumn 221, Issue 5, 2016, Pages 679-689

  Castiblanco Valencia, Mónica Marcela ^a   Fraga, Tatiana Rodrigues ^a   Pagotto, Ana Helena ^b   de Toledo Serrano, Solange Maria ^b   Abreu, Patricia Antonia Estima ^b   Barbosa, Angela Silva ^b   Isaac, Lourdes ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTO BUTANTAN   (Brazil)

Author keywords

Complement; Immune evasion; Leptospira; Lig proteins; Plasminogen

Indexed keywords

BACTERIAL PROTEIN; COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C5; FIBRINOGEN; LEPTOSPIRAL IMMUNOGLOBULIN LIKE PROTEIN A; LEPTOSPIRAL IMMUNOGLOBULIN LIKE PROTEIN B; LYSINE; PLASMIN; PLASMINOGEN; UNCLASSIFIED DRUG; UROKINASE; BACTERIAL ANTIGEN; C4BPA PROTEIN, HUMAN; COMPLEMENT COMPONENT C4B BINDING PROTEIN; PROTEIN BINDING;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; HOST PATHOGEN INTERACTION; IMMUNE EVASION; IONIC STRENGTH; LEPTOSPIRA INTERROGANS; MICROBIAL ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; ENZYME ACTIVATION; HUMAN; IMMUNOLOGY; LEPTOSPIROSIS; METABOLISM; OSMOLARITY;

ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BINDING SITES; COMPLEMENT C3B; COMPLEMENT C4B-BINDING PROTEIN; COMPLEMENT C5; ENZYME ACTIVATION; FIBRINOGEN; FIBRINOLYSIN; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNE EVASION; LEPTOSPIRA INTERROGANS; LEPTOSPIROSIS; OSMOLAR CONCENTRATION; PROTEIN BINDING; PROTEOLYSIS;

EID: 84960503773     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2016.01.001     Document Type: Article

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