Staphylococcus aureus α toxin potentiates opportunistic bacterial lung infections

Science Translational Medicine

Volumn 8, Issue 329, 2016, Pages

  Cohen, Taylor S ^a   Hilliard, Jamese J ^a   Jones Nelson, Omari ^a   Keller, Ashley E ^a   O'Day, Terrence ^a   Tkaczyk, Christine ^a   Digiandomenico, Antonio ^a   Hamilton, Melissa ^a   Pelletier, Mark ^a   Wang, Qun ^a   Diep, Binh An ^b,c   Le, Vien T M ^b   Cheng, Lily ^a   Suzich, Joann ^a   Stover, C Kendall ^a   Sellman, Bret R ^a  

^a MEDIMMUNE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

STAPHYLOCOCCUS ALPHA TOXIN; ACID; BACTERIAL TOXIN; BACTERIUM ANTIBODY; CALPAIN; HEMOLYSIN; MONOCLONAL ANTIBODY; STAPHYLOCOCCAL ALPHA-TOXIN;

ACIDIFICATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL GROWTH; CONTROLLED STUDY; DISEASE SEVERITY; LUNG ALVEOLUS CELL; LUNG INFECTION; LYSOSOME; MIXED INFECTION; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; TOXIN ANALYSIS; ANIMAL; BIOLOGICAL MODEL; DRUG EFFECTS; ENZYME ACTIVATION; GROWTH, DEVELOPMENT AND AGING; HUMAN; IMMUNOLOGY; LUNG ALVEOLUS MACROPHAGE; METABOLISM; MICROBIAL VIABILITY; MICROBIOLOGY; NATURAL KILLER CELL; NEUTROPHIL; OPPORTUNISTIC INFECTION; PATHOLOGY; PNEUMONIA; PSEUDOMONAS AERUGINOSA; RESPIRATORY TRACT INFECTION; STAPHYLOCOCCUS INFECTION;

ACIDS; ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODIES, MONOCLONAL; BACTERIAL TOXINS; CALPAIN; COINFECTION; ENZYME ACTIVATION; HEMOLYSIN PROTEINS; HUMANS; KILLER CELLS, NATURAL; LYSOSOMES; MACROPHAGES, ALVEOLAR; MICE; MICROBIAL VIABILITY; MODELS, BIOLOGICAL; NEUTROPHILS; OPPORTUNISTIC INFECTIONS; PNEUMONIA; PSEUDOMONAS AERUGINOSA; RESPIRATORY TRACT INFECTIONS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 84960435725     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aad9922     Document Type: Article

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