Deacetylation of MnSOD by PARP-regulated SIRT3 protects retinal capillary endothelial cells from hyperglycemia-induced damage

Biochemical and Biophysical Research Communications

Volumn 472, Issue 3, 2016, Pages 425-431

  Gao, Jian ^a   Zheng, Zhi ^a   Gu, Qing ^a   Chen, Xia ^a   Liu, Xiaoxiao ^a   Xu, Xun ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Diabetic retinopathy; MnSOD; PARP; Reactive oxygen species; SIRT3

Indexed keywords

GLUCOSE; HISTONE DEACETYLASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; N (5,6 DIHYDRO 6 OXO 2 PHENANTHRIDINYL) 2 DIMETHYLAMINOACETAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; SIRTUIN 3; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DEACETYLATION; DIABETIC RETINOPATHY; DOWN REGULATION; ENZYME ACTIVITY; FLOW CYTOMETRY; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ACETYLATION; PROTEIN EXPRESSION; RAT; RETINA CAPILLARY; WESTERN BLOTTING; ACETYLATION; ANIMAL; BOVINE; CAPILLARY; CELL CULTURE; ENDOTHELIUM CELL; ENZYME ACTIVATION; METABOLISM; PATHOLOGY; RETINA BLOOD VESSEL;

ACETYLATION; ANIMALS; CAPILLARIES; CATTLE; CELLS, CULTURED; DIABETIC RETINOPATHY; ENDOTHELIAL CELLS; ENZYME ACTIVATION; GLUCOSE; HYPERGLYCEMIA; POLY(ADP-RIBOSE) POLYMERASES; RETINAL VESSELS; SIRTUIN 3; SUPEROXIDE DISMUTASE;

EID: 84960371324     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.12.037     Document Type: Article

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