Pioneering Activity of the C-Terminal Domain of EBF1 Shapes the Chromatin Landscape for B Cell Programming

Immunity

Volumn 44, Issue 3, 2016, Pages 527-541

  Boller, Sören ^a   Ramamoorthy, Senthilkumar ^a   Akbas, Duygu ^a   Nechanitzky, Robert ^a   Burger, Lukas ^b,c   Murr, Rabih ^b   Schübeler, Dirk ^b   Grosschedl, Rudolf ^a  

^a MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^b FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^c SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

Author keywords

B lymphopoiesis; Chromatin; DNA methylation; DNaseI hypersensitivity; EBF1; Pioneer transcription factor

Indexed keywords

DEOXYRIBONUCLEASE I; DNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EBF1; UNCLASSIFIED DRUG; CHROMATIN; EBF1 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CARBOXY TERMINAL SEQUENCE; CELL FATE; CELL SPECIFICITY; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOARCHITECTURE; DEMETHYLATION; DNA METHYLATION; GENE EXPRESSION; GENE REPRESSION; GENE TARGETING; GENETIC ASSOCIATION; HYPERSENSITIVITY; IN VITRO STUDY; LYMPHOCYTE DIFFERENTIATION; NONHUMAN; NUCLEAR REPROGRAMMING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; STEM CELL; TRANSACTIVATION; TRANSCRIPTION INITIATION; WILD TYPE; ANIMAL; CELL CULTURE; CELL DIFFERENTIATION; CELL LINEAGE; GENE REGULATORY NETWORK; GENETICS; KNOCKOUT MOUSE; LYMPHOID PROGENITOR CELL; LYMPHOPOIESIS; METABOLISM; MOUSE; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; TRANSGENIC MOUSE;

ANIMALS; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; CHROMATIN; DNA METHYLATION; GENE REGULATORY NETWORKS; LYMPHOID PROGENITOR CELLS; LYMPHOPOIESIS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PROTEIN STRUCTURE, TERTIARY; TRANS-ACTIVATORS;

EID: 84960370159     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2016.02.021     Document Type: Article

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