Active enhancers are delineated de novo during hematopoiesis, with limited lineage fidelity among specified primary blood cells

Genes and Development

Volumn 28, Issue 16, 2014, Pages 1827-1839

  Luyten, Annouck ^a,d   Zang, Chongzhi ^b,d   Liu, X Shirley ^b   Shivdasani, Ramesh A ^a,c,d  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

Chromatin dynamics; Hematopoiesis; Nucleosome dynamics; Tissue differentiation; Tissue selective enhancers

Indexed keywords

ERYTHROPOIETIN; HISTONE H3; HISTONE H3K4ME1; HISTONE H3K4ME2; STEM CELL FACTOR; THROMBOPOIETIN; TRANSCRIPTION FACTOR GATA 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BLOOD CELL; CELL DIFFERENTIATION; CELL LINEAGE; CELL RENEWAL; CHROMATIN IMMUNOPRECIPITATION; COLONY FORMING UNIT GM; CONTROLLED STUDY; ENHANCER REGION; ERYTHROID CELL; GENE ACTIVITY; GENE EXPRESSION; GRANULOCYTE; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; INTESTINE CRYPT; MEGAKARYOCYTE ERYTHROID PROGENITOR; MOUSE; MULTIPOTENT STEM CELL; MYELOID PROGENITOR CELL; NONHUMAN; NUCLEOSOME; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROGENY; PROMOTER REGION; QUANTITATIVE ANALYSIS;

CHROMATIN DYNAMICS; HEMATOPOIESIS; NUCLEOSOME DYNAMICS; TISSUE DIFFERENTIATION; TISSUE-SELECTIVE ENHANCERS;

ANIMALS; BLOOD CELLS; CELL DIFFERENTIATION; CELL LINEAGE; ENHANCER ELEMENTS, GENETIC; EPIGENESIS, GENETIC; HEMATOPOIESIS; HISTONES; MICE; STEM CELLS;

EID: 84906098540     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.240101.114     Document Type: Article

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