메뉴 건너뛰기




Volumn 100, Issue 12, 2016, Pages 5527-5536

NAD+-specific glutamate dehydrogenase (EC.1.4.1.2) in Streptomyces coelicolor; in vivo characterization and the implication for nutrient-dependent secondary metabolism

Author keywords

DasR; Glucose; Glutamate dehydrogenase; N acetylglucosamine; Secondary metabolism

Indexed keywords

ANTIBIOTICS; BACTERIA; BIOCHEMISTRY; GENES; GLUCOSE; NITROGEN; NUTRIENTS; PHYSIOLOGY;

EID: 84960361056     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-016-7433-8     Document Type: Article
Times cited : (9)

References (41)
  • 1
    • 0036526451 scopus 로고    scopus 로고
    • Carbon flux distribution in antibiotic-producing chemostat cultures of Streptomyces lividans
    • COI: 1:STN:280:DC%2BD383ntVGrug%3D%3D
    • Avignone Rossa C, White J, Kuiper A, Postma PW, Bibb M, Teixeira de Mattos MJ (2002) Carbon flux distribution in antibiotic-producing chemostat cultures of Streptomyces lividans. Met Eng. 4(2):138–150. doi:10.1006/mben.2001.0217
    • (2002) Met Eng. , vol.4 , Issue.2 , pp. 138-150
    • Avignone Rossa, C.1    White, J.2    Kuiper, A.3    Postma, P.W.4    Bibb, M.5    Teixeira de Mattos, M.J.6
  • 2
    • 33746606019 scopus 로고    scopus 로고
    • Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry
    • COI: 1:CAS:528:DC%2BD28Xns12nt7k%3D
    • Bajad SU, Lu W, Kimball EH, Yuan J, Peterson C, Rabinowitz JD (2006) Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry. J Chromato A 1125(1):76–88. doi:10.1016/j.chroma.2006.05.019
    • (2006) J Chromato A , vol.1125 , Issue.1 , pp. 76-88
    • Bajad, S.U.1    Lu, W.2    Kimball, E.H.3    Yuan, J.4    Peterson, C.5    Rabinowitz, J.D.6
  • 4
    • 20444397992 scopus 로고    scopus 로고
    • Genome-scale analysis of Streptomyces coelicolor A3(2) metabolism
    • COI: 1:CAS:528:DC%2BD2MXlt1yjsrg%3D
    • Borodina I, Krabben P, Nielsen J (2005) Genome-scale analysis of Streptomyces coelicolor A3(2) metabolism. Gen Res. 15(6):820–829. doi:10.1101/gr.3364705
    • (2005) Gen Res. , vol.15 , Issue.6 , pp. 820-829
    • Borodina, I.1    Krabben, P.2    Nielsen, J.3
  • 5
    • 54449101282 scopus 로고    scopus 로고
    • Antibiotic overproduction in Streptomyces coelicolor A3(2) mediated by phosphofructokinase deletion
    • COI: 1:CAS:528:DC%2BD1cXhtVyisL3I
    • Borodina I, Siebring J, Zhang J, Smith CP, van Keulen G, Dijkhuizen L, Nielsen J (2008) Antibiotic overproduction in Streptomyces coelicolor A3(2) mediated by phosphofructokinase deletion. J Bio Chem 283(37):25186–25199. doi:10.1074/jbc.M803105200
    • (2008) J Bio Chem , vol.283 , Issue.37 , pp. 25186-25199
    • Borodina, I.1    Siebring, J.2    Zhang, J.3    Smith, C.P.4    van Keulen, G.5    Dijkhuizen, L.6    Nielsen, J.7
  • 6
    • 0022649643 scopus 로고
    • Pathways and regulation of ammonium assimilation in Streptomyces clavuligerus
    • COI: 1:CAS:528:DyaL28Xkt1Wnt7o%3D
    • Brana A, Paiva N, Demain A (1986) Pathways and regulation of ammonium assimilation in Streptomyces clavuligerus. J Gen Microbiol 132:1305–1317
    • (1986) J Gen Microbiol , vol.132 , pp. 1305-1317
    • Brana, A.1    Paiva, N.2    Demain, A.3
  • 7
    • 0001880173 scopus 로고
    • Detection of glutamine synthetase activity in marine phytoplankton: optimization of biosynthetic assay
    • Bressler SaA S (1984) Detection of glutamine synthetase activity in marine phytoplankton: optimization of biosynthetic assay. Marin Eco-progress series 14:207–217
    • (1984) Marin Eco-progress series , vol.14 , pp. 207-217
    • Bressler SaA, S.1
  • 8
    • 0036231769 scopus 로고    scopus 로고
    • The polyphosphate kinase plays a negative role in the control of antibiotic production in Streptomyces lividans
    • COI: 1:CAS:528:DC%2BD38Xit1Gns7Y%3D, PID: 11929542
    • Chouayekh H, Virolle MJ (2002) The polyphosphate kinase plays a negative role in the control of antibiotic production in Streptomyces lividans. Mol Microbiol 43(4):919–930
    • (2002) Mol Microbiol , vol.43 , Issue.4 , pp. 919-930
    • Chouayekh, H.1    Virolle, M.J.2
  • 9
    • 75749085389 scopus 로고    scopus 로고
    • Noncoding RNA of glutamine synthetase I modulates antibiotic production in Streptomyces coelicolor A3(2)
    • PID: 19966003
    • D’Alia D, Nieselt K, Steigele S, Muller J, Verburg I, Takano E (2010) Noncoding RNA of glutamine synthetase I modulates antibiotic production in Streptomyces coelicolor A3(2). J Bacteriol 192(4):1160–1164. doi:10.1128/JB.01374-09
    • (2010) J Bacteriol , vol.192 , Issue.4 , pp. 1160-1164
    • D’Alia, D.1    Nieselt, K.2    Steigele, S.3    Muller, J.4    Verburg, I.5    Takano, E.6
  • 10
    • 18744383916 scopus 로고    scopus 로고
    • Two transcriptional regulators GlnR and GlnRII are involved in regulation of nitrogen metabolism in Streptomyces coelicolor A3(2)
    • COI: 1:CAS:528:DC%2BD38XosVarsb0%3D, PID: 12406212
    • Fink D, Weissschuh N, Reuther J, Wohlleben W, Engels A (2002) Two transcriptional regulators GlnR and GlnRII are involved in regulation of nitrogen metabolism in Streptomyces coelicolor A3(2). Mol Microbiol 46(2):331–347
    • (2002) Mol Microbiol , vol.46 , Issue.2 , pp. 331-347
    • Fink, D.1    Weissschuh, N.2    Reuther, J.3    Wohlleben, W.4    Engels, A.5
  • 11
    • 0024673082 scopus 로고
    • Glutamate synthesis in Streptomyces coelicolor
    • COI: 1:CAS:528:DyaL1MXktVeqsbo%3D, PID: 2708309
    • Fisher SH (1989) Glutamate synthesis in Streptomyces coelicolor. J Bacteriol 171(5):2372–2377
    • (1989) J Bacteriol , vol.171 , Issue.5 , pp. 2372-2377
    • Fisher, S.H.1
  • 12
    • 0024670364 scopus 로고
    • Regulation of glutamine synthetase in Streptomyces coelicolor
    • COI: 1:CAS:528:DyaL1MXktVCjsbY%3D, PID: 2468647
    • Fisher SH, Wray LV Jr (1989) Regulation of glutamine synthetase in Streptomyces coelicolor. J Bacteriol 171(5):2378–2383
    • (1989) J Bacteriol , vol.171 , Issue.5 , pp. 2378-2383
    • Fisher, S.H.1    Wray, L.V.2
  • 13
    • 77955343496 scopus 로고    scopus 로고
    • Deletion of a regulatory gene within the CPK gene cluster reveals novel antibacterial activity in Streptomyces coelicolor A3(2)
    • COI: 1:CAS:528:DC%2BC3cXhtFSltLvJ
    • Gottelt M, Kol S, Gomez-Escribano JP, Bibb M, Takano E (2010) Deletion of a regulatory gene within the CPK gene cluster reveals novel antibacterial activity in Streptomyces coelicolor A3(2). Microbiol. 156(Pt 8):2343–2353. doi:10.1099/mic.0.038281-0
    • (2010) Microbiol. , vol.156 , pp. 2343-2353
    • Gottelt, M.1    Kol, S.2    Gomez-Escribano, J.P.3    Bibb, M.4    Takano, E.5
  • 14
    • 0037452723 scopus 로고    scopus 로고
    • PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin
    • COI: 1:CAS:528:DC%2BD3sXhsFGktrY%3D, PID: 12563033
    • Gust B, Challis GL, Fowler K, Kieser T, Chater KF (2003) PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin. PNAS 100(4):1541–1546. doi:10.1073/pnas.0337542100
    • (2003) PNAS , vol.100 , Issue.4 , pp. 1541-1546
    • Gust, B.1    Challis, G.L.2    Fowler, K.3    Kieser, T.4    Chater, K.F.5
  • 15
    • 84864093517 scopus 로고    scopus 로고
    • A blue native polyacrylamide gel electrophoretic technology to probe the functional proteomics mediating nitrogen homeostasis in Pseudomonas fluorescens
    • COI: 1:CAS:528:DC%2BC38XotVWjs7Y%3D, PID: 22595184
    • Han S, Auger C, Appanna VP, Lemire J, Castonguay Z, Akbarov E, Appanna VD (2012) A blue native polyacrylamide gel electrophoretic technology to probe the functional proteomics mediating nitrogen homeostasis in Pseudomonas fluorescens. J Microbiol Methods 90(3):206–210. doi:10.1016/j.mimet.2012.05.006
    • (2012) J Microbiol Methods , vol.90 , Issue.3 , pp. 206-210
    • Han, S.1    Auger, C.2    Appanna, V.P.3    Lemire, J.4    Castonguay, Z.5    Akbarov, E.6    Appanna, V.D.7
  • 16
    • 0036430005 scopus 로고    scopus 로고
    • The GlnD and GlnK homologues of Streptomyces coelicolor A3(2) are functionally dissimilar to their nitrogen regulatory system counterparts from enteric bacteria
    • COI: 1:CAS:528:DC%2BD38XosVarsbw%3D, PID: 12406211
    • Hesketh A, Fink D, Gust B, Rexer HU, Scheel B, Chater K, Wohlleben W, Engels A (2002) The GlnD and GlnK homologues of Streptomyces coelicolor A3(2) are functionally dissimilar to their nitrogen regulatory system counterparts from enteric bacteria. Mol Microbiol 46(2):319–330
    • (2002) Mol Microbiol , vol.46 , Issue.2 , pp. 319-330
    • Hesketh, A.1    Fink, D.2    Gust, B.3    Rexer, H.U.4    Scheel, B.5    Chater, K.6    Wohlleben, W.7    Engels, A.8
  • 17
    • 1542677181 scopus 로고    scopus 로고
    • Purification and properties of glutamate synthase from Streptomyces lincolnensis
    • COI: 1:CAS:528:DyaK1cXitVGnu7Y%3D
    • Jin Z, Jiao R (1998) Purification and properties of glutamate synthase from Streptomyces lincolnensis. Sci in China C 41(1):37–46. doi:10.1007/BF02882704
    • (1998) Sci in China C , vol.41 , Issue.1 , pp. 37-46
    • Jin, Z.1    Jiao, R.2
  • 18
    • 84858403229 scopus 로고    scopus 로고
    • GlmS and NagB regulate amino sugar metabolism in opposing directions and affect Streptococcus mutans virulence
    • COI: 1:CAS:528:DC%2BC38XkvVOqtLY%3D, PID: 22438919
    • Kawada-Matsuo M, Mazda Y, Oogai Y, Kajiya M, Kawai T, Yamada S, Miyawaki S, Oho T, Komatsuzawa H (2012) GlmS and NagB regulate amino sugar metabolism in opposing directions and affect Streptococcus mutans virulence. PLoS One 7(3):e33382. doi:10.1371/journal.pone.0033382
    • (2012) PLoS One , vol.7 , Issue.3
    • Kawada-Matsuo, M.1    Mazda, Y.2    Oogai, Y.3    Kajiya, M.4    Kawai, T.5    Yamada, S.6    Miyawaki, S.7    Oho, T.8    Komatsuzawa, H.9
  • 20
    • 84870687706 scopus 로고    scopus 로고
    • NdgR, a common transcriptional activator for methionine and leucine biosynthesis in Streptomyces coelicolor
    • COI: 1:CAS:528:DC%2BC38XhvVahtLjK, PID: 23065973
    • Kim SH, Lee BR, Kim JN, Kim BG (2012) NdgR, a common transcriptional activator for methionine and leucine biosynthesis in Streptomyces coelicolor. J Bacteriol 194(24):6837–6846. doi:10.1128/JB.00695-12
    • (2012) J Bacteriol , vol.194 , Issue.24 , pp. 6837-6846
    • Kim, S.H.1    Lee, B.R.2    Kim, J.N.3    Kim, B.G.4
  • 21
    • 0026715777 scopus 로고
    • A method for the determination of changes of glycolytic metabolites in yeast on a subsecond time scale using extraction at neutral pH
    • PID: 1514678
    • de Koning W, van Dam K (1992) A method for the determination of changes of glycolytic metabolites in yeast on a subsecond time scale using extraction at neutral pH. Anal Biochem 204(1):118–123
    • (1992) Anal Biochem , vol.204 , Issue.1 , pp. 118-123
    • de Koning, W.1    van Dam, K.2
  • 22
    • 0037136238 scopus 로고    scopus 로고
    • Stress-response sigma factor sigma (H) directs expression of the gltB gene encoding glutamate synthase in Streptomyces coelicolor A3(2)
    • COI: 1:CAS:528:DC%2BD38XlvVeqs70%3D
    • Kormanec J, Sevcikova B (2002) Stress-response sigma factor sigma (H) directs expression of the gltB gene encoding glutamate synthase in Streptomyces coelicolor A3(2). Biochim et Biophys Acta. 1577(1):149–154
    • (2002) Biochim et Biophys Acta. , vol.1577 , Issue.1 , pp. 149-154
    • Kormanec, J.1    Sevcikova, B.2
  • 23
    • 0021888766 scopus 로고
    • Pathway of ammonium assimilation in Streptomyces venezuelae examined by amino acid analyses and 15 N nuclear magnetic resonance spectroscopy
    • COI: 1:STN:280:DyaL2M3otFygsQ%3D%3D, PID: 2862983
    • Laycock M, McInnes AG, Walter JA, Shapiro S, Vining LC (1985) Pathway of ammonium assimilation in Streptomyces venezuelae examined by amino acid analyses and 15 N nuclear magnetic resonance spectroscopy. Can J Microbiol 31(7):629–634
    • (1985) Can J Microbiol , vol.31 , Issue.7 , pp. 629-634
    • Laycock, M.1    McInnes, A.G.2    Walter, J.A.3    Shapiro, S.4    Vining, L.C.5
  • 24
    • 33646082272 scopus 로고    scopus 로고
    • Rational strain improvement for enhanced clavulanic acid production by genetic engineering of the glycolytic pathway in Streptomyces clavuligerus
    • COI: 1:CAS:528:DC%2BD28XjvVGgsbw%3D
    • Li R, Townsend CA (2006) Rational strain improvement for enhanced clavulanic acid production by genetic engineering of the glycolytic pathway in Streptomyces clavuligerus. Met Eng. 8(3):240–252. doi:10.1016/j.ymben.2006.01.003
    • (2006) Met Eng. , vol.8 , Issue.3 , pp. 240-252
    • Li, R.1    Townsend, C.A.2
  • 25
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(−delta delta C(T)) method
    • COI: 1:CAS:528:DC%2BD38XhtFelt7s%3D, PID: 11846609
    • Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(−delta delta C(T)) method. Methods 25(4):402–408. doi:10.1006/meth.2001.1262
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 26
    • 0036010144 scopus 로고    scopus 로고
    • The role of glutamine synthetase and glutamate dehydrogenase in nitrogen assimilation and possibilities for improvement in the nitrogen utilization of crops
    • COI: 1:CAS:528:DC%2BD38XivFSnur8%3D
    • Miflin BJ, Habash DZ (2002) The role of glutamine synthetase and glutamate dehydrogenase in nitrogen assimilation and possibilities for improvement in the nitrogen utilization of crops. J Exp Botany. 53(370):979–987
    • (2002) J Exp Botany. , vol.53 , Issue.370 , pp. 979-987
    • Miflin, B.J.1    Habash, D.Z.2
  • 27
    • 0034671553 scopus 로고    scopus 로고
    • A new class of glutamate dehydrogenases (GDH). Biochemical and genetic characterization of the first member, the AMP-requiring NAD-specific GDH of Streptomyces clavuligerus
    • COI: 1:CAS:528:DC%2BD3cXptFSrt7s%3D, PID: 10924516
    • Minambres B, Olivera ER, Jensen RA, Luengo JM (2000) A new class of glutamate dehydrogenases (GDH). Biochemical and genetic characterization of the first member, the AMP-requiring NAD-specific GDH of Streptomyces clavuligerus. J Biol Chem. 275(50):39529–39542. doi:10.1074/jbc.M005136200
    • (2000) J Biol Chem. , vol.275 , Issue.50 , pp. 39529-39542
    • Minambres, B.1    Olivera, E.R.2    Jensen, R.A.3    Luengo, J.M.4
  • 29
    • 15744405123 scopus 로고    scopus 로고
    • PII signal transduction proteins: sensors of alpha-ketoglutarate that regulate nitrogen metabolism
    • COI: 1:CAS:528:DC%2BD2MXivFSlsbg%3D, PID: 15802248
    • Ninfa AJ, Jiang P (2005) PII signal transduction proteins: sensors of alpha-ketoglutarate that regulate nitrogen metabolism. Curr Opin Microbiol 8(2):168–173. doi:10.1016/j.mib.2005.02.011
    • (2005) Curr Opin Microbiol , vol.8 , Issue.2 , pp. 168-173
    • Ninfa, A.J.1    Jiang, P.2
  • 30
    • 71049184750 scopus 로고    scopus 로고
    • Analysis and identification of ADP-ribosylated proteins of Streptomyces coelicolor M145
    • COI: 1:CAS:528:DC%2BD1MXhtlWisLjP, PID: 19851727
    • Penyige A, Keseru J, Fazakas F, Schmelczer I, Szirak K, Barabas G, Biro S (2009) Analysis and identification of ADP-ribosylated proteins of Streptomyces coelicolor M145. J Microbiol 47(5):549–556. doi:10.1007/s12275-009-0032-y
    • (2009) J Microbiol , vol.47 , Issue.5 , pp. 549-556
    • Penyige, A.1    Keseru, J.2    Fazakas, F.3    Schmelczer, I.4    Szirak, K.5    Barabas, G.6    Biro, S.7
  • 31
    • 84876325985 scopus 로고    scopus 로고
    • Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer
    • COI: 1:CAS:528:DC%2BC3sXotl2kt70%3D, PID: 23401619
    • Ratcliffe PJ (2013) Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer. J Physiol 591(Pt 8):2027–2042. doi:10.1113/jphysiol.2013.251470
    • (2013) J Physiol , vol.591 , pp. 2027-2042
    • Ratcliffe, P.J.1
  • 32
    • 33751394705 scopus 로고    scopus 로고
    • Investigation of the functional properties and regulation of three glutamine synthetase-like genes in Streptomyces coelicolor A3(2)
    • COI: 1:CAS:528:DC%2BD28Xht1elsbjL, PID: 16932908
    • Rexer HU, Schaberle T, Wohlleben W, Engels A (2006) Investigation of the functional properties and regulation of three glutamine synthetase-like genes in Streptomyces coelicolor A3(2). Arch Microbiol 186(6):447–458. doi:10.1007/s00203-006-0159-8
    • (2006) Arch Microbiol , vol.186 , Issue.6 , pp. 447-458
    • Rexer, H.U.1    Schaberle, T.2    Wohlleben, W.3    Engels, A.4
  • 33
    • 46449120734 scopus 로고    scopus 로고
    • Feast or famine: the global regulator DasR links nutrient stress to antibiotic production by Streptomyces
    • COI: 1:CAS:528:DC%2BD1cXnvV2rs7Y%3D, PID: 18511939
    • Rigali S, Titgemeyer F, Barends S, Mulder S, Thomae AW, Hopwood DA, van Wezel GP (2008) Feast or famine: the global regulator DasR links nutrient stress to antibiotic production by Streptomyces. EMBO Rep 9(7):670–675. doi:10.1038/embor.2008.83
    • (2008) EMBO Rep , vol.9 , Issue.7 , pp. 670-675
    • Rigali, S.1    Titgemeyer, F.2    Barends, S.3    Mulder, S.4    Thomae, A.W.5    Hopwood, D.A.6    van Wezel, G.P.7
  • 34
    • 33750969392 scopus 로고    scopus 로고
    • Engineering of primary carbohydrate metabolism for increased production of actinorhodin in Streptomyces coelicolor
    • COI: 1:CAS:528:DC%2BD28Xht1Gksr%2FI
    • Ryu YG, Butler MJ, Chater KF, Lee KJ (2006) Engineering of primary carbohydrate metabolism for increased production of actinorhodin in Streptomyces coelicolor. App Environ Microbiol. 72(11):7132–7139. doi:10.1128/AEM.01308-06
    • (2006) App Environ Microbiol. , vol.72 , Issue.11 , pp. 7132-7139
    • Ryu, Y.G.1    Butler, M.J.2    Chater, K.F.3    Lee, K.J.4
  • 35
    • 84873620230 scopus 로고    scopus 로고
    • Competition between the GlnR and PhoP regulators for the glnA and amtB promoters in Streptomyces coelicolor
    • COI: 1:CAS:528:DC%2BC3sXhvV2msLk%3D
    • Sola-Landa A, Rodriguez-Garcia A, Amin R, Wohlleben W, Martin JF (2013) Competition between the GlnR and PhoP regulators for the glnA and amtB promoters in Streptomyces coelicolor. NA Research 41(3):1767–1782. doi:10.1093/nar/gks1203
    • (2013) NA Research , vol.41 , Issue.3 , pp. 1767-1782
    • Sola-Landa, A.1    Rodriguez-Garcia, A.2    Amin, R.3    Wohlleben, W.4    Martin, J.F.5
  • 36
    • 11844250010 scopus 로고    scopus 로고
    • The bkdR gene of Streptomyces coelicolor is required for morphogenesis and antibiotic production and encodes a transcriptional regulator of a branched-chain amino acid dehydrogenase complex
    • COI: 1:CAS:528:DC%2BD2MXmtVCrug%3D%3D, PID: 15629937
    • Sprusansky O, Stirrett K, Skinner D, Denoya C, Westpheling J (2005) The bkdR gene of Streptomyces coelicolor is required for morphogenesis and antibiotic production and encodes a transcriptional regulator of a branched-chain amino acid dehydrogenase complex. J Bacteriol 187(2):664–671. doi:10.1128/JB.187.2.664-671.2005
    • (2005) J Bacteriol , vol.187 , Issue.2 , pp. 664-671
    • Sprusansky, O.1    Stirrett, K.2    Skinner, D.3    Denoya, C.4    Westpheling, J.5
  • 37
    • 0026030777 scopus 로고
    • The stringent response in Streptomyces coelicolor A3(2)
    • COI: 1:CAS:528:DyaK3MXhvVWqsrY%3D, PID: 1710311
    • Strauch E, Takano E, Baylis HA, Bibb MJ (1991) The stringent response in Streptomyces coelicolor A3(2). Mol Microbiol 5(2):289–298
    • (1991) Mol Microbiol , vol.5 , Issue.2 , pp. 289-298
    • Strauch, E.1    Takano, E.2    Baylis, H.A.3    Bibb, M.J.4
  • 38
    • 84874681854 scopus 로고    scopus 로고
    • The ROK family regulator Rok7B7 pleiotropically affects xylose utilization, carbon catabolite repression, and antibiotic production in Streptomyces coelicolor
    • COI: 1:CAS:528:DC%2BC3sXlsFWgsr0%3D, PID: 23292782
    • Swiatek MA, Gubbens J, Bucca G, Song E, Yang YH, Laing E, Kim BG, Smith CP, van Wezel GP (2013) The ROK family regulator Rok7B7 pleiotropically affects xylose utilization, carbon catabolite repression, and antibiotic production in Streptomyces coelicolor. J Bacteriol 195(6):1236–1248. doi:10.1128/JB.02191-12
    • (2013) J Bacteriol , vol.195 , Issue.6 , pp. 1236-1248
    • Swiatek, M.A.1    Gubbens, J.2    Bucca, G.3    Song, E.4    Yang, Y.H.5    Laing, E.6    Kim, B.G.7    Smith, C.P.8    van Wezel, G.P.9
  • 39
    • 0024828702 scopus 로고
    • Purification and properties of NADP-dependent glutamate dehydrogenase from Streptomyces fradiae
    • COI: 1:CAS:528:DyaK3cXpsVersw%3D%3D, PID: 2561488
    • Vancurova I, Vancura A, Volc J, Kopecky J, Neuzil J, Basarova G, Behal V (1989) Purification and properties of NADP-dependent glutamate dehydrogenase from Streptomyces fradiae. J Gen Microbiol 135(12):3311–3318
    • (1989) J Gen Microbiol , vol.135 , Issue.12 , pp. 3311-3318
    • Vancurova, I.1    Vancura, A.2    Volc, J.3    Kopecky, J.4    Neuzil, J.5    Basarova, G.6    Behal, V.7
  • 40
    • 0036333349 scopus 로고    scopus 로고
    • Effects of alpha-ketoglutarate on lipid peroxidation and antioxidant status during chronic ethanol administration in Wistar rats
    • COI: 1:CAS:528:DC%2BD38XotV2msrk%3D
    • Velvizhi S, Nagalashmi T, Essa MM, Dakshayani KB, Subramanian P (2002) Effects of alpha-ketoglutarate on lipid peroxidation and antioxidant status during chronic ethanol administration in Wistar rats. Polish J Pharmacol. 54(3):231–236
    • (2002) Polish J Pharmacol. , vol.54 , Issue.3 , pp. 231-236
    • Velvizhi, S.1    Nagalashmi, T.2    Essa, M.M.3    Dakshayani, K.B.4    Subramanian, P.5
  • 41
    • 84865616728 scopus 로고    scopus 로고
    • Intracellular metabolite pool changes in response to nutrient depletion induced metabolic switching in Streptomyces coelicolor
    • COI: 1:CAS:528:DC%2BC38Xlt1Ciu7Y%3D, PID: 24957373
    • Wentzel A, S. H, Consortium SE, Bruheim P (2012) Intracellular metabolite pool changes in response to nutrient depletion induced metabolic switching in Streptomyces coelicolor. Metabolites 2(1):178–194. doi:10.3390/metabo2010178
    • (2012) Metabolites , vol.2 , Issue.1 , pp. 178-194
    • Wentzel, A.1    Consortium, S.E.2    Bruheim, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.