The Aspergillus fumigatus damage resistance protein family coordinately regulates ergosterol biosynthesis and azole susceptibility

mBio

Volumn 7, Issue 1, 2016, Pages

  Song, Jinxing ^a   Zhai, Pengfei ^a   Zhang, Yuanwei ^a   Zhang, Caiyun ^b   Sang, Hong ^b   Han, Guanzhu ^a   Keller, Nancy P ^c   Lu, Ling ^a  

^a NANJING NORMAL UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; DAMAGE RESISTANCE PROTEIN; DAPA PROTEIN; DAPB PROTEIN; DAPC PROTEIN; ERG5 PROTEIN; ERGOSTEROL; FUNGAL PROTEIN; HEME; HEMIN; ITRACONAZOLE; PYRROLE DERIVATIVE; STEROL 14ALPHA DEMETHYLASE; UNCLASSIFIED DRUG; VORICONAZOLE; ANTIFUNGAL AGENT; CARRIER PROTEIN; CYB5 PROTEIN, RAT; FUNGAL DNA; HEMOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIFUNGAL RESISTANCE; ANTIFUNGAL SUSCEPTIBILITY; ARTICLE; ASPERGILLUS FUMIGATUS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FEMALE; FUNGAL VIRULENCE; LUNG ASPERGILLOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; STEROL SYNTHESIS; SURVIVAL RATE; ANIMAL; BIOSYNTHESIS; DISEASE MODEL; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOCOMPROMISED PATIENT; METABOLISM; MICROBIOLOGY; MUTATION;

ANIMALS; ANTIFUNGAL AGENTS; ASPERGILLUS FUMIGATUS; AZOLES; CARRIER PROTEINS; CYTOCHROME P-450 ENZYME SYSTEM; DISEASE MODELS, ANIMAL; DNA, FUNGAL; DRUG RESISTANCE, FUNGAL; ERGOSTEROL; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; HEME; HEME-BINDING PROTEINS; HEMEPROTEINS; IMMUNOCOMPROMISED HOST; MICE; MUTATION; PULMONARY ASPERGILLOSIS;

EID: 84960193502     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.01919-15     Document Type: Article

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