Risk of cancer in children conceived by assisted reproductive technology

Pediatrics

Volumn 137, Issue 3, 2016, Pages

  Reigstad, Marte Myhre ^a,b   Larsen, Inger Kristin ^b   Myklebust, Tor Åge ^b   Robsahm, Trude Eid ^b   Oldereid, Nan Birgitte ^a   Brinton, Louise A ^c   Storeng, Ritsa ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b CANCER REGISTRY OF NORWAY   (Norway)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE LYMPHOBLASTIC LEUKEMIA; ACUTE MYELOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; ASTROCYTOMA; BONE TUMOR; BURKITT LYMPHOMA; CANCER DIAGNOSIS; CANCER MORTALITY; CANCER REGISTRY; CANCER RISK; CANCER STAGING; CENTRAL NERVOUS SYSTEM TUMOR; CHILD; CHILDBIRTH; COHORT ANALYSIS; CONTROLLED STUDY; EPENDYMOMA; FEMALE; FOLLOW UP; GERM CELL TUMOR; HODGKIN DISEASE; HUMAN; INFERTILITY THERAPY; KIDNEY TUMOR; LEUKEMIA; LIVER TUMOR; LYMPHOMA; MAJOR CLINICAL STUDY; MALE; MIGRATION; MYELOPROLIFERATIVE DISORDER; NEUROBLASTOMA; NONHODGKIN LYMPHOMA; NORWAY; POPULATION RESEARCH; PRIORITY JOURNAL; RETINOBLASTOMA; RISK ASSESSMENT; SOFT TISSUE SARCOMA; CENTRAL NERVOUS SYSTEM NEOPLASMS; INFANT; NEOPLASMS; PRESCHOOL CHILD; REGISTER; RISK FACTOR;

ADOLESCENT; CENTRAL NERVOUS SYSTEM NEOPLASMS; CHILD; CHILD, PRESCHOOL; FEMALE; HODGKIN DISEASE; HUMANS; INFANT; LEUKEMIA; MALE; NEOPLASMS; NORWAY; REGISTRIES; REPRODUCTIVE TECHNIQUES, ASSISTED; RISK FACTORS;

EID: 84960146464     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2015-2061     Document Type: Article

References (62)

1. Sunderam S, Kissin DM, Crawford S, et al; Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, CDC. Assisted reproductive technology surveillance-United States, 2010. MMWR Surveill Summ. 2013;62(9):1-24
2. Talaulikar VS, Arulkumaran S. Reproductive outcomes after assisted conception. Obstet Gynecol Surv. 2012;67(9):566-583
3. Tararbit K, Houyel L, Bonnet D, et al. Risk of congenital heart defects associated with assisted reproductive technologies: a populationbased evaluation. Eur Heart J. 2011;32(4):500-508
4. Rudant J, Amigou A, Orsi L, et al. Fertility treatments, congenital malformations, fetal loss, and childhood acute leukemia: the ESCALE study (SFCE). Pediatr Blood Cancer. 2013;60(2):301-308
5. Mayor S. Risk of congenital malformations in children born after assisted reproduction is higher than previously thought. BMJ. 2010;340:c3191
6. Hansen M, Kurinczuk JJ, Milne E, De Klerk N, Bower C. Assisted reproductive technology and birth defects: a systematic review and meta-analysis. Hum Reprod Update. 2013;19(4):330-353
7. Kettner LO, Henriksen TB, Bay B, Ramlau-Hansen CH, Kesmodel US. Assisted reproductive technology and somatic morbidity in childhood: a systematic review. Fertil Steril. 2015;103(3):707-719
8. Melamed I, Bujanover Y, Hammer J, Spirer Z. Hepatoblastoma in an infant born to a mother after hormonal treatment for sterility. N Engl J Med. 1982;307(13):820
9. White L, Giri N, Vowels MR, Lancaster PA. Neuroectodermal tumours in children born after assisted conception. Lancet. 1990;336(8730):1577
10. Kobayashi N, Matsui I, Tanimura M, et al. Childhood neuroectodermal tumours and malignant lymphoma after maternal ovulation induction. Lancet. 1991;338(8772):955
11. Toren A, Sharon N, Mandel M, et al. Two embryonal cancers after in vitro fertilization. Cancer. 1995;76(11):2372-2374
12. Fraumeni JF Jr, Miller RW, Hill JA. Primary carcinoma of the liver in childhood: an epidemiologic study. J Natl Cancer Inst. 1968;40(5):1087-1099
13. Inbar-Feigenberg M, Choufani S, Butcher DT, Roifman M, Weksberg R. Basic concepts of epigenetics. Fertil Steril. 2013;99(3):607-615
14. Odom LN, Taylor HS. Environmental induction of the fetal epigenome. Expert Rev Obstet Gynecol. 2010;5(6):657-664
15. Källén B, Finnström O, Lindam A, Nilsson E, Nygren KG, Olausson PO. Cancer risk in children and young adults conceived by in vitro fertilization. Pediatrics. 2010;126(2):270-276
16. Hargreave M, Jensen A, Deltour I, Brinton LA, Andersen KK, Kjaer SK. Increased risk for cancer among offspring of women with fertility problems. Int J Cancer. 2013;133(5):1180-1186
17. Hargreave M, Jensen A, Toender A, Andersen KK, Kjaer SK. Fertility treatment and childhood cancer risk: a systematic meta-analysis. Fertil Steril. 2013;100(1):150-161
18. Hargreave M, Jensen A, Nielsen TS, et al. Maternal use of fertility drugs and risk of cancer in children-a nationwide population-based cohort study in Denmark. Int J Cancer. 2015;136(8):1931-1939
19. Petridou ET, Sergentanis TN, Panagopoulou P, et al. In vitro fertilization and risk of childhood leukemia in Greece and Sweden. Pediatr Blood Cancer. 2012;58(6):930-936
20. Sundh KJ, Henningsen AK, Källen K, et al. Cancer in children and young adults born after assisted reproductive technology: a Nordic cohort study from the Committee of Nordic ART and Safety (CoNARTaS). Hum Reprod. 2014;29(9):2050-2057
21. McLaughlin CC, Baptiste MS, Schymura MJ, Nasca PC, Zdeb MS. Maternal and infant birth characteristics and hepatoblastoma. Am J Epidemiol. 2006;163(9):818-828
22. Marees T, Dommering CJ, Imhof SM, et al. Incidence of retinoblastoma in Dutch children conceived by IVF: an expanded study. Hum Reprod. 2009;24(12):3220-3224
23. Michalek AM, Buck GM, Nasca PC, Freedman AN, Baptiste MS, Mahoney MC. Gravid health status, medication use, and risk of neuroblastoma. Am J Epidemiol. 1996;143(10):996-1001
24. Klip H, Burger CW, De Kraker J, Van Leeuwen FE; OMEGA-project group. Risk of cancer in the offspring of women who underwent ovarian stimulation for IVF. Hum Reprod. 2001;16(11):2451-2458
25. Brinton LA, Krüger Kjaer S, Thomsen BL, et al. Childhood tumor risk after treatment with ovulationstimulating drugs. Fertil Steril. 2004;81(4):1083-1091
26. Puumala SE, Ross JA, Olshan AF, Robison LL, Smith FO, Spector LG. Reproductive history, infertility treatment, and the risk of acute leukemia in children with down syndrome: a report from the Children's Oncology Group. Cancer. 2007;110(9):2067-2074
27. Bruinsma F, Venn A, Lancaster P, Speirs A, Healy D. Incidence of cancer in children born after in-vitro fertilization. Hum Reprod. 2000;15(3):604-607
28. Larsen IK, Småstuen M, Johannesen TB, et al. Data quality at the Cancer Registry of Norway: an overview of comparability, completeness, validity and timeliness. Eur J Cancer. 2009;45(7):1218-1231
29. Zegers-Hochschild F, Adamson GD, De Mouzon J, et al; International Committee for Monitoring Assisted Reproductive Technology; World Health Organization. The International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) revised glossary on ART terminology, 2009. Hum Reprod. 2009;24(11):2683-2687
30. Steliarova-Foucher E, Stiller C, Lacour B, Kaatsch P. International Classification of Childhood Cancer, Third Edition. Cancer. 2005;103(7):1457-1467
31. Johnson KJ, Carozza SE, Chow EJ, et al. Parental age and risk of childhood cancer: a pooled analysis. Epidemiology. 2009;20(4):475-483
32. Johnson KJ, Soler JT, Puumala SE, Ross JA, Spector LG. Parental and infant characteristics and childhood leukemia in Minnesota. BMC Pediatr. 2008;8:7
33. Dunson DB, Colombo B, Baird DD. Changes with age in the level and duration of fertility in the menstrual cycle. Hum Reprod. 2002;17(5):1399-1403
34. Dockerty JD, Draper G, Vincent T, Rowan SD, Bunch KJ. Case-control study of parental age, parity and socioeconomic level in relation to childhood cancers. Int J Epidemiol. 2001;30(6):1428-1437
35. Schüz J, Luta G, Erdmann F, et al. Birth order and risk of childhood cancer in the Danish birth cohort of 1973-2010. Cancer Causes Control. 2015;26(11):1575-1582
36. Oksuzyan S, Crespi CM, Cockburn M, Mezei G, Kheifets L. Birth weight and other perinatal characteristics and childhood leukemia in California. Cancer Epidemiol. 2012;36(6):e359-e365
37. O'Neill KA, Murphy MF, Bunch KJ, et al. Infant birthweight and risk of childhood cancer: international population-based case control studies of 40 000 cases. Int J Epidemiol. 2015;44(1):153-168
38. Crump C, Sundquist J, Sieh W, Winkleby MA, Sundquist K. Perinatal and familial risk factors for brain tumors in childhood through young adulthood. Cancer Res. 2015;75(3):576-583
39. Bjørge T, Sørensen HT, Grotmol T, et al. Fetal growth and childhood cancer: a population-based study. Pediatrics. 2013;132 (5). Available at: www.pediatrics.org/cgi/content/full/132/5/e1265
40. Petridou ET, Sergentanis TN, Skalkidou A, et al. Maternal and birth anthropometric characteristics in relation to the risk of childhood lymphomas: a Swedish nationwide cohort study. Eur J Cancer Prev. 2015;24(6):535-541
41. Williams CL, Bunch KJ, Stiller CA, et al. Cancer risk among children born after assisted conception. N Engl J Med. 2013;369(19):1819-1827
42. Ericson A, Nygren KG, Olausson PO, Källén B. Hospital care utilization of infants born after IVF. Hum Reprod. 2002;17(4):929-932
43. Bergh T, Ericson A, Hillensjö T, Nygren KG, Wennerholm UB. Deliveries and children born after in-vitro fertilisation in Sweden 1982-95: a retrospective cohort study. Lancet. 1999;354(9190):1579-1585
44. Doyle P, Bunch KJ, Beral V, Draper GJ. Cancer incidence in children conceived with assisted reproduction technology. Lancet. 1998;352(9126):452-453
45. Lerner-Geva L, Toren A, Chetrit A, et al. The risk for cancer among children of women who underwent in vitro fertilization. Cancer. 2000;88(12):2845-2847
46. Schüz J, Kaatsch P, Kaletsch U, Meinert R, Michaelis J. Association of childhood cancer with factors related to pregnancy and birth. Int J Epidemiol. 1999;28(4):631-639
47. Bradbury BD, Jick H. In vitro fertilization and childhood retinoblastoma. Br J Clin Pharmacol. 2004;58(2):209-211
48. Foix-L'Hélias L, Aerts I, Marchand L, et al. Are children born after infertility treatment at increased risk of retinoblastoma? Hum Reprod. 2012;27(7):2186-2192
49. Moll AC, Imhof SM, Cruysberg JR, Schouten-Van Meeteren AY, Boers M, Van Leeuwen FE. Incidence of retinoblastoma in children born after in-vitro fertilisation. Lancet. 2003;361(9354):309-310
50. Cancer Registry of Norway, Institute of Population-Based Cancer Research. Cancer in Norway 2013-Cancer incidence, mortality, survival and prevalence in Norway. Available at: http://www.kreftregisteret.no/en/General/Publications/Cancer-in-Norway/Cancer-in-Norway-2013/. Accessed August 1, 2016
51. Puumala SE, Ross JA, Feusner JH, et al. Parental infertility, infertility treatment and hepatoblastoma: a report from the Children's Oncology Group. Hum Reprod. 2012;27(6):1649-1656
52. Heck JE, Lombardi CA, Cockburn M, Meyers TJ, Wilhelm M, Ritz B. Epidemiology of rhabdoid tumors of early childhood. Pediatr Blood Cancer. 2013;60(1):77-81
53. Belson M, Kingsley B, Holmes A. Risk factors for acute leukemia in children: a review. Environ Health Perspect. 2007;115(1):138-145
54. Spycher BD, Lupatsch JE, Zwahlen M, et al. Background ionizing radiation and the risk of childhood cancer: a census-based nationwide cohort study. Environ Health Perspect. 2015;123(6):622-628
55. Wrensch M, Minn Y, Chew T, Bondy M, Berger MS. Epidemiology of primary brain tumors: current concepts and review of the literature. Neuro-oncol. 2002;4(4):278-299
56. Herbst AL. Diethylstilbestrol and adenocarcinoma of the vagina. Am J Obstet Gynecol. 1999;181(6):1576-1578, discussion 1579
57. Keegan TJ, Bunch KJ, Vincent TJ, et al. Case-control study of paternal occupation and social class with risk of childhood central nervous system tumours in Great Britain, 1962-2006. Br J Cancer. 2013;108(9):1907-1914
58. Sharma R, Agarwal A, Rohra VK, Assidi M, Abu-Elmagd M, Turki RF. Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspring. Reprod Biol Endocrinol. 2015;13(1):35
59. Van Steensel-Moll HA, Valkenburg HA, Vandenbroucke JP, Van Zanen GE. Are maternal fertility problems related to childhood leukaemia? Int J Epidemiol. 1985;14(4):555-559
60. Odom LN, Segars J. Imprinting disorders and assisted reproductive technology. Curr Opin Endocrinol Diabetes Obes. 2010;17(6):517-522
61. De Baun MR, Tucker MA. Risk of cancer during the first four years of life in children from the Beckwith-Wiedemann Syndrome Registry. J Pediatr. 1998;132(3 pt 1):398-400
62. Bjørge T, Cnattingius S, Lie RT, Tretli S, Engeland A. Cancer risk in children with birth defects and in their families: a population based cohort study of 5.2 million children from Norway and Sweden. Cancer Epidemiol Biomarkers Prev. 2008;17(3):500-506